{"info":{"_postman_id":"cdbb35e0-9b62-42c7-93aa-54230abb31b2","name":"LifeDNA API","schema":"https://schema.getpostman.com/json/collection/v2.0.0/collection.json","toc":[],"description":"","owner":"9155408","collectionId":"cdbb35e0-9b62-42c7-93aa-54230abb31b2","publishedId":"Tz5p4wwv","public":true,"customColor":{"top-bar":"FFFFFF","right-sidebar":"303030","highlight":"41C752"},"publishDate":"2021-03-10T22:11:25.000Z"},"item":[{"name":"Customer","item":[{"name":"Create Customer","id":"363b9ee0-6dfe-4236-bbe8-2f42e8bada83","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"email\": \"testendpoint@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"test\", //Required\r\n \"gender\": \"man\", //Required allowed values (man,woman,male,female)\r\n \"hashed_password\": \"$2y$12$dUxVbNbS27KMIwMmZz2mJO.VnzytaLmzIBIxaoXQJ9AKYh9jYzrPe\" // Optional\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/create/customer","description":"

Description: This Endpoint is used to create a customer on our API server

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type	Notes
public_key	Required	String
partner_id	Required	String
email	Required	String
first_name	Required	String
last_name	Required	String
gender	Required	String	Allowed values (man, woman, male, female)

hashed_password	Optional	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

customer_id

String

","urlObject":{"path":["create","customer"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"07e9c3f2-7bf0-4a4a-9b07-d0ee386329e7","name":"Create Customer - Customer Already Exists Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"email\": \"test1@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"test\", //Required\r\n \"gender\": \"male\" //Required allowed values (man,woman,male,female)\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/create/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"e1fff4c0bd484e3867e1bcf55d94e02f\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"3fb287ef-a22c-4e19-b77d-809cc74859ee"},{"key":"X-Runtime","value":"0.008706"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Customer Already Exists\",\n \"customer_id\": \"cus_10d3d1f24ed5_7e9840ae90b5_a5b9b5b6cff9\"\n}"},{"id":"336423d2-1153-4fbf-bb43-3032ac007fff","name":"Create Customer - Missing Paramter Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"email\": \"test1@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"test\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/create/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"765f793306b26fbc693dd60b1ea0667f\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"b9738ea8-504c-4500-bbc8-cdfff952b150"},{"key":"X-Runtime","value":"0.004095"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Required parameter 'gender' missing\",\n \"customer_id\": \"\"\n}"},{"id":"81ef61b3-e576-4010-95e0-77db71591ab4","name":"Create Customer - Invalid Partner ID/ Public Key","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"invalid partner id\", //Required\r\n \"email\": \"test@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"test\", //Required\r\n \"gender\": \"male\" //Required allowed values (man,woman,male,female)\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/create/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"5e92882028117ba008341b726e54b2ed\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"6b8e5dfb-9fd2-4cd3-8b70-ab86073f168c"},{"key":"X-Runtime","value":"0.005172"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\",\n \"customer_id\": \"\"\n}"},{"id":"dd7b3708-d1c2-4779-9b18-ea7361ee08aa","name":"Create Customer Successful Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"email\": \"test1@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"test\", //Required\r\n \"gender\": \"male\" //Required allowed values (man,woman,male,female)\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/create/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"beb056852cb9a7e89316a07fd0cdee39\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"076072a5-3f21-4b8c-8653-6aaa0d7a0b39"},{"key":"X-Runtime","value":"0.021978"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Customer Created\",\n \"customer_id\": \"cus_10d3d1f24ed5_7e9840ae90b5_a5b9b5b6cff9\"\n}"},{"id":"f2647548-a10e-446e-990c-0e858059a84c","name":"Create Customer - Invalid gender format response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"email\": \"test12@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"test\", //Required\r\n \"gender\": \"other\" //Required allowed values (man,woman,male,female)\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/create/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"de2b27e686543271c42203605fc8f502\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"54bb6205-0c74-47a3-a855-c4a599d1dab8"},{"key":"X-Runtime","value":"0.008314"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Unsupported gender (should be man/woman)\",\n \"customer_id\": \"\"\n}"}],"_postman_id":"363b9ee0-6dfe-4236-bbe8-2f42e8bada83"},{"name":"Update Customer","id":"22640348-fff1-44e2-84e9-4e4917d56b1f","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_a1f4bdb1afb2_2f662c373548_56ad0b098cdc\", //Required\r\n \"email\": \"test@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"lifedna\", //Required\r\n \"gender\": \"male\", //Required\r\n \"hashed_password\": \"$2y$12$dUxVbNbS27KMIwMmZz2mJO.VnzytaLmzIBIxaoXQJ9AKYh9jYzrPe\" // Optional\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/update/customer","description":"

Description: This endpoint is used for updating customer's personal info.

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type	Notes
public_key	Required	String
partner_id	Required	String
email	Required	String
first_name	Required	String
last_name	Required	String
gender	Required	String	Allowed values (man, woman, male, female)
customer_id	Required	String
hashed_password	Optional	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

","urlObject":{"path":["update","customer"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"150efd3c-5210-4dfc-89a8-d43fedf1b925","name":"Update Customer - Invalid Partner ID/ Public Key","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"invalid partner id\", //Required\r\n \"customer_id\": \"cus_a1f4bdb1afb2_2f662c373548_56ad0b098cdc\", //Required\r\n \"email\": \"test@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"lifedna\", //Required\r\n \"gender\": \"male\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/update/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"c6f639ed6cc5dfa888c7fd5e1a8b57c6\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"b2f74502-c3ed-4cde-9d7a-84841561765c"},{"key":"X-Runtime","value":"0.005454"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\"\n}"},{"id":"231018bd-699e-4a04-abbc-18d95c3503ec","name":"Update Customer - Email Already Exists Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_a1f4bdb1afb2_2f662c373548_56ad0b098cdc\", //Required\r\n \"email\": \"test1@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"lifedna\", //Required\r\n \"gender\": \"male\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/update/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"cc4ca5f15c4a853e4759686d6e6d6c63\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"3d0de3f2-2cc5-4c14-96c2-2293add1eddb"},{"key":"X-Runtime","value":"0.014329"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"403\",\n \"message\": \"Email Already exists\"\n}"},{"id":"483ddb4a-78fd-4418-888b-d062393730fc","name":"Update Customer - Successful Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_a1f4bdb1afb2_2f662c373548_56ad0b098cdc\", //Required\r\n \"email\": \"test@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"lifedna\", //Required\r\n \"gender\": \"male\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/update/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"6dbc3904ef4ec234c70ab5848e2159a1\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"4fa3eda9-423b-4cd3-8217-8206f83c224f"},{"key":"X-Runtime","value":"0.012395"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Customer Updated\"\n}"},{"id":"9d3b1b71-ed21-4719-ba58-69d5820a1bbb","name":"Update Customer - Missing Paramter Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_a1f4bdb1afb2_2f662c373548_56ad0b098cdc\", //Required\r\n \"email\": \"test@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"lifedna\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/update/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"c4d847ab4be55e17f74671ff99896119\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"f7b9c133-6a3e-497c-b1ce-31c1895ded7e"},{"key":"X-Runtime","value":"0.004226"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Required parameter 'gender' missing\"\n}"},{"id":"d317531d-64b4-4371-a0ac-b689592bdf6f","name":"Update Customer - Invalid gender response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_a1f4bdb1afb2_2f662c373548_56ad0b098cdc\", //Required\r\n \"email\": \"test@lifedna.com\", //Required\r\n \"first_name\": \"test\", //Required\r\n \"last_name\": \"lifedna\", //Required\r\n \"gender\": \"other\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/update/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"3daebcf0dc002c411272689a5b8f7bc0\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"5385adf1-35f1-482e-b5a5-8f97df54c96b"},{"key":"X-Runtime","value":"0.007150"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Unsupported gender (should be man/woman)\"\n}"}],"_postman_id":"22640348-fff1-44e2-84e9-4e4917d56b1f"},{"name":"Get customer","id":"77395cd8-4e63-467f-b251-92c9b936cc5a","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1e1d545b04d8_6df480781379_babcc1e2cca8\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/get/customer","description":"

Description: This endpoint retrieves all info about the customer (personal info , shipping address, customer accesses, and whether the customer has uploaded a DNA already or not).

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

customer

JSON Object

-id
-email
-first_name
-last_name
-gender
-has_shipping_address
-address_line_1
-address_line_2
-country
-state
-zip_code
-user_accesses
-has_dna

","urlObject":{"path":["get","customer"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"1259b6a8-e3ac-41b3-ac38-1020f16d6554","name":"Get customer - Successful Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1e1d545b04d8_6df480781379_babcc1e2cca8\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/get/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"3a26cd7dd865ca76da83bed2eb0d7a89\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"1fc870bb-b643-4947-afcf-2142bbaa2d92"},{"key":"X-Runtime","value":"0.010736"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Customer Retrieved\",\n \"customer\": {\n \"id\": \"cus_1e1d545b04d8_6df480781379_babcc1e2cca8\",\n \"email\": \"dnatest33@lifedna.com\",\n \"first_name\": \"dna\",\n \"last_name\": \"test\",\n \"gender\": \"man\",\n \"has_shipping_address\": false,\n \"address_line_1\": null,\n \"address_line_2\": null,\n \"country\": null,\n \"state\": null,\n \"zip_code\": null,\n \"user_accesses\": [],\n \"has_dna\": true\n }\n}"},{"id":"5f3bce3e-b2be-4f93-8cf7-85ac04d366dc","name":"Get customer - Invalid Partner ID/ Public Key","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1e1d545b04d8_6df480781379_babcc1e2cca8\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/get/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"bb6131102f94f71e9f33663d1d90238f\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"d0b4e7c1-6fa7-47d5-8f12-fcfe2b95e0cb"},{"key":"X-Runtime","value":"0.005419"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\",\n \"customer\": {}\n}"},{"id":"b7014d37-7d7e-474e-82b1-7e70ed38de25","name":"Get customer - Customer Not Found Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1e1d545b04d8_6df480781379_babcc1e2cca8\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/get/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"2299ad575503c6804e87e72a54ac79f5\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"f41569da-1fdd-4dfc-80f1-2e951eda435a"},{"key":"X-Runtime","value":"0.006439"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Customer Not Found\",\n \"customer\": {}\n}"},{"id":"fbc6ede0-4d43-492d-a684-247780941afb","name":"Get customer - Missing Paramter Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1e1d545b04d8_6df480781379_babcc1e2cca8\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/get/customer"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"7f71b373a48301d79579a9ea825902cc\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"3b6a2743-b823-479d-a52f-989de1650577"},{"key":"X-Runtime","value":"0.004135"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Required parameter 'customer_id' missing\",\n \"customer\": {}\n}"}],"_postman_id":"77395cd8-4e63-467f-b251-92c9b936cc5a"}],"id":"035f4079-1b26-4bd9-96a7-419d97a478c9","_postman_id":"035f4079-1b26-4bd9-96a7-419d97a478c9","description":""},{"name":"Shipping Address","item":[{"name":"Shipping Address","id":"d74be1b4-4423-4912-898a-969c3bba6a66","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_4f5a9ad88e24_2870fd77cabd_926e72ab332d\", //Required\r\n \"address_line_1\": \"test street\", //Required\r\n \"country\": \"US\", //Required\r\n \"state\": \"HI\", //Required\r\n \"zip_code\": \"4934809234\", //Required\r\n \"address_line_2\": \"\" //Optional\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/update/shipping/address","description":"

Description: This endpoint creates or update customer's billing/shipping address

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String
address_line_1	Required	String
country	Required	String
state	Required	String
zip_code	Required	String
address_line_2	Optional	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

","urlObject":{"path":["update","shipping","address"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"544dceb6-a6d8-4d40-b060-83999be7bbed","name":"Shipping Address - Customer Not Found Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_4f5a9ad88e24_2870fd77cabd_926e72ab332d1\", //Required\r\n \"address_line_1\": \"test street\", //Required\r\n \"country\": \"US\", //Required\r\n \"state\": \"HI\", //Required\r\n \"zip_code\": \"4934809234\", //Required\r\n \"address_line_2\": \"\" //Optional\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/update/shipping/address"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"3b13c279e93bf88695a1ce6c61348f7e\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"d4098e51-ef66-4fc7-9964-f096d8c778d1"},{"key":"X-Runtime","value":"0.007573"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Customer Not Found\"\n}"},{"id":"8569a638-aec7-4de5-9bca-0fd488fc6f13","name":"Shipping Address - Successful Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_4f5a9ad88e24_2870fd77cabd_926e72ab332d\", //Required\r\n \"address_line_1\": \"test street\", //Required\r\n \"country\": \"US\", //Required\r\n \"state\": \"HI\", //Required\r\n \"zip_code\": \"4934809234\", //Required\r\n \"address_line_2\": \"\" //Optional\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/update/shipping/address"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"3b1094a0f88cdd99489c97b8a1323ca8\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"71de9f7c-b5d4-403e-9a89-e3950209c929"},{"key":"X-Runtime","value":"0.050299"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Shipping Address Updated\"\n}"},{"id":"bcfc355b-bbf8-464f-82ee-f74076c0f15e","name":"Shipping Address - Invalid Partner ID/ Public Key","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"invalid partner id\", //Required\r\n \"customer_id\": \"cus_4f5a9ad88e24_2870fd77cabd_926e72ab332d\", //Required\r\n \"address_line_1\": \"test street\", //Required\r\n \"country\": \"US\", //Required\r\n \"state\": \"HI\", //Required\r\n \"zip_code\": \"4934809234\", //Required\r\n \"address_line_2\": \"\" //Optional\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/update/shipping/address"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"c6f639ed6cc5dfa888c7fd5e1a8b57c6\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"945105b7-505f-40b1-aa23-d8ae74198ef0"},{"key":"X-Runtime","value":"0.005707"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\"\n}"},{"id":"e36cb15b-6b93-4fc7-8e4b-348b1655abd7","name":"Shipping Address - Missing Required Paramter","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_4f5a9ad88e24_2870fd77cabd_926e72ab332d\", //Required\r\n \"address_line_1\": \"test street\", //Required\r\n \"country\": \"US\", //Required\r\n \"state\": \"HI\", //Required\r\n \"address_line_2\": \"\" //Optional\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/update/shipping/address"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"26ec069467956be4fc421e2f8c0990ba\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"06b50053-05bc-4749-95fe-c24602c2c10d"},{"key":"X-Runtime","value":"0.003489"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Required parameter 'zip_code' missing\"\n}"}],"_postman_id":"d74be1b4-4423-4912-898a-969c3bba6a66"}],"id":"df77c44b-5173-4b5b-aac2-10caad2e1445","_postman_id":"df77c44b-5173-4b5b-aac2-10caad2e1445","description":""},{"name":"DNA Endpoints","item":[{"name":"Upload DNA","id":"29872d6e-5489-4124-94b6-807f7f5ee1e0","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1c2b7b12b289_709f9fd16bb5_8aafce768660\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/dna/upload","description":"

Description: This endpoint stores the customer's sent DNA to our servers and use it for generating the report

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

","urlObject":{"path":["dna","upload"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"43c62daf-2e57-49fc-ab69-040b4bb5ccac","name":"Upload DNA - Invalid Partner ID/ Public Key","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"invalid partner id\", //Required\r\n \"customer_id\": \"cus_85d77fdbbd79_9d7f1b7a153c_1bc7f0df697c\" //Required\r\n\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/dna/upload"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"30f503a48cf2acac390836c5ae8f3e6b\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"949dd26d-343c-4b2c-8b64-fa4299c34ec2"},{"key":"X-Runtime","value":"0.012902"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\",\n \"dna_data\": []\n}"},{"id":"738499de-58d0-4a02-85ca-b5f2e261dbd9","name":"Upload DNA - Customer Already Has A DNA Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_85d77fdbbd79_9d7f1b7a153c_1bc7f0df697c\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/dna/upload"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"beaf46fad420fc75ee1c41c06dec2276\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"b04efacb-ac40-4cf6-8eea-269bb5e263e5"},{"key":"X-Runtime","value":"0.015484"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Customer already has DNA\",\n \"dna_data\": []\n}"},{"id":"7f2b28e9-cc2b-4d9f-a768-4e8b55b11703","name":"Upload DNA - Successful Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required \r\n \"customer_id\": \"cus_85d77fdbbd79_9d7f1b7a153c_1bc7f0df697c\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/dna/upload"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"5d53936eb4c90fab2a7a482f85094460\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"a42ff9db-d218-4a61-9bc4-f9b0bad3f796"},{"key":"X-Runtime","value":"0.074645"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"DNA uploaded\",\n \"dna_data\": []\n}"},{"id":"e5584f2b-9f55-4241-b6b9-202d16f1cb94","name":"Upload DNA - Missing Required Parameter Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/dna/upload"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"f925f0e3a8055614e5f57ef2b357552c\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"5478231d-ab1f-47d5-8219-f051448b3531"},{"key":"X-Runtime","value":"0.012891"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Required parameter 'customer_id' missing\",\n \"dna_data\": []\n}"},{"id":"ef61bd81-4fb9-4281-8291-43073c5d24fe","name":"Upload DNA - Customer Not Found Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\",\r\n \"partner_id\": \"{{partner_id}}\",\r\n \"customer_id\": \"cus_85d77fdbbd79_9d7f1b7a153c_1bc7f0df697c1\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/dna/upload"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"f1198860a3e27eeea6b2f78e194edadc\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"6d797721-e1eb-437d-bef0-1a7e74208107"},{"key":"X-Runtime","value":"0.024781"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Customer Not Found\",\n \"dna_data\": []\n}"}],"_postman_id":"29872d6e-5489-4124-94b6-807f7f5ee1e0"},{"name":"DNA Reset","id":"f4b803d3-f2e3-4816-b761-31dfd1de54d8","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required \r\n \"customer_id\": \"cus_e6e375632f09_c911da689ed5_004b766fb831\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/reset/customer/dna","description":"

Description: This endpoint deletes customer’s DNA

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

","urlObject":{"path":["reset","customer","dna"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"b4475900-b3b9-4564-a41a-fc26c4d2d496","name":"DNA Reset - Invalid Partner ID/ Public Key","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"invalid partner id\", //Required \r\n \"customer_id\": \"cus_85d77fdbbd79_9d7f1b7a153c_1bc7f0df697c\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/reset/customer/dna"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"c6f639ed6cc5dfa888c7fd5e1a8b57c6\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"24d5d254-16a3-4ad1-9c92-5dfa1b2bdc57"},{"key":"X-Runtime","value":"0.011465"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\"\n}"},{"id":"db8b5bc9-0261-43ec-a957-b311cb8154d5","name":"DNA Reset - Successful Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required \r\n \"customer_id\": \"cus_85d77fdbbd79_9d7f1b7a153c_1bc7f0df697c\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/reset/customer/dna"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"dd8f232f07dbc0ea59ff13668381f88d\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"a1594568-83e2-4599-81ae-3b4919705c86"},{"key":"X-Runtime","value":"0.020618"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"DNA Deleted\"\n}"},{"id":"e3401d00-3971-4a87-b378-37b2dcfb8a5f","name":"DNA Reset - Missing Parameter Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\" //Required \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/reset/customer/dna"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"725a59dec71af82bedba0dddfb50f591\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"b1ef70ba-9473-4549-9816-6ae467e5258f"},{"key":"X-Runtime","value":"0.003225"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Required parameter 'customer_id' missing\"\n}"},{"id":"fa0ef3ec-bac0-4d9d-81f7-14ab64b7246b","name":"DNA Reset - Customer Not Found Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required \r\n \"customer_id\": \"cus_85d77fdbbd79_9d7f1b7a153c_1bc7f0df697c1\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/reset/customer/dna"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"3b13c279e93bf88695a1ce6c61348f7e\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"8e22e459-8017-4464-af47-ae8878f7d4e9"},{"key":"X-Runtime","value":"0.008050"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Customer Not Found\"\n}"}],"_postman_id":"f4b803d3-f2e3-4816-b761-31dfd1de54d8"}],"id":"77d6a70e-f276-422c-9383-2ed4fcd7c28e","_postman_id":"77d6a70e-f276-422c-9383-2ed4fcd7c28e","description":""},{"name":"Kits Endpoints","item":[{"name":"Request Kit Endpoint","id":"18485911-8bf0-464a-a09b-1532513d15c6","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/kit","description":"

Description: This endpoint requests a DNA kit for the customer

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

","urlObject":{"path":["request","kit"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"2956253c-29bb-4f6a-ad08-c931801fdd20","name":"Request Kit Endpoint - Successful Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/kit"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"Date","value":"Wed, 17 Mar 2021 16:20:23 GMT"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"Transfer-Encoding","value":"chunked"},{"key":"Connection","value":"keep-alive"},{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"ETag","value":"W/\"b1d6d7252ba8c404f0618afcd724754f\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"70e3c583-51ec-443e-8f43-e7b17e62144e"},{"key":"X-Runtime","value":"0.039016"},{"key":"CF-Cache-Status","value":"DYNAMIC"},{"key":"cf-request-id","value":"08e2960f0b0000ee71ce2cb000000001"},{"key":"Expect-CT","value":"max-age=604800, report-uri=\"https://report-uri.cloudflare.com/cdn-cgi/beacon/expect-ct\""},{"key":"Report-To","value":"{\"group\":\"cf-nel\",\"max_age\":604800,\"endpoints\":[{\"url\":\"https:\\/\\/a.nel.cloudflare.com\\/report?s=9uHSfnUr9wHnMqdd%2BHKsaiQT6cHGAZ0VoOmnt6do70XUYgO%2BgxuGqw3klE2YjbfebzFiP%2FmJPj%2B2bTujcBxrJV3Mqt%2FgTJZl7Q2lOJWnTYnDPQ9Wbet1\"}]}"},{"key":"NEL","value":"{\"report_to\":\"cf-nel\",\"max_age\":604800}"},{"key":"Server","value":"cloudflare"},{"key":"CF-RAY","value":"63178c5e7a7aee71-CDG"},{"key":"Content-Encoding","value":"br"},{"key":"alt-svc","value":"h3-27=\":443\"; ma=86400, h3-28=\":443\"; ma=86400, h3-29=\":443\"; ma=86400"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Kit Requested\",\n \"sample_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec\"\n}"},{"id":"6a65e170-fdb2-4c3b-981f-fe63e3d6cdc1","name":"Request Kit Endpoint - Already Has A Kit Or Uploaded DNA","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/kit"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"Date","value":"Wed, 17 Mar 2021 16:20:42 GMT"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"Transfer-Encoding","value":"chunked"},{"key":"Connection","value":"keep-alive"},{"key":"x-frame-options","value":"SAMEORIGIN"},{"key":"x-xss-protection","value":"1; mode=block"},{"key":"x-content-type-options","value":"nosniff"},{"key":"x-download-options","value":"noopen"},{"key":"x-permitted-cross-domain-policies","value":"none"},{"key":"referrer-policy","value":"strict-origin-when-cross-origin"},{"key":"etag","value":"W/\"43a6f5644d0a94fcefcdda1c349c1af3\""},{"key":"cache-control","value":"max-age=0, private, must-revalidate"},{"key":"x-request-id","value":"15b68457-af1d-413b-a2fb-a69e3b1be2cb"},{"key":"x-runtime","value":"0.009616"},{"key":"CF-Cache-Status","value":"DYNAMIC"},{"key":"cf-request-id","value":"08e29658560000ee71b1a48000000001"},{"key":"Expect-CT","value":"max-age=604800, report-uri=\"https://report-uri.cloudflare.com/cdn-cgi/beacon/expect-ct\""},{"key":"Report-To","value":"{\"group\":\"cf-nel\",\"max_age\":604800,\"endpoints\":[{\"url\":\"https:\\/\\/a.nel.cloudflare.com\\/report?s=gPrKtn%2B%2FVUvUOsNgN7cmDDHq0WlaofAycH3VIgGpRpqhn4XqPMajM4v4JjuGyWEXLBCUQ7P0gJ6YKBRz9F72tT8hE9bMi7s3pWFHFA4Zg9xkHrEFA%2Bnz\"}]}"},{"key":"NEL","value":"{\"report_to\":\"cf-nel\",\"max_age\":604800}"},{"key":"Server","value":"cloudflare"},{"key":"CF-RAY","value":"63178cd3ba7bee71-CDG"},{"key":"Content-Encoding","value":"br"},{"key":"alt-svc","value":"h3-27=\":443\"; ma=86400, h3-28=\":443\"; ma=86400, h3-29=\":443\"; ma=86400"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Customer already has DNA Or Requested a DNA Kit\"\n}"},{"id":"812e5c37-c853-4091-9a8d-50ca2294e761","name":"Request Kit Endpoint - Shipping Country Oustide US or Canada","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/kit"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"Date","value":"Wed, 17 Mar 2021 16:19:49 GMT"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"Transfer-Encoding","value":"chunked"},{"key":"Connection","value":"keep-alive"},{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"ETag","value":"W/\"4799aa967c5fc78ffa01874b5bb83cba\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"047481b7-a3a9-4615-9f87-1466dd61e593"},{"key":"X-Runtime","value":"0.012324"},{"key":"CF-Cache-Status","value":"DYNAMIC"},{"key":"cf-request-id","value":"08e29588f40000ee71cda58000000001"},{"key":"Expect-CT","value":"max-age=604800, report-uri=\"https://report-uri.cloudflare.com/cdn-cgi/beacon/expect-ct\""},{"key":"Report-To","value":"{\"group\":\"cf-nel\",\"max_age\":604800,\"endpoints\":[{\"url\":\"https:\\/\\/a.nel.cloudflare.com\\/report?s=MZx6KILU%2FOEYHECi1x%2FYBNkK3jvYuidV8p%2F4DaQQkreY7aBTZ1WpVhpPamHK7OTUDOb0ahhhGpLZQEehYeUTz7O1B0nEv9ti3i0Hb%2F5V%2BlS6acYzBG56\"}]}"},{"key":"NEL","value":"{\"report_to\":\"cf-nel\",\"max_age\":604800}"},{"key":"Server","value":"cloudflare"},{"key":"CF-RAY","value":"63178b87e8e0ee71-CDG"},{"key":"Content-Encoding","value":"br"},{"key":"alt-svc","value":"h3-27=\":443\"; ma=86400, h3-28=\":443\"; ma=86400, h3-29=\":443\"; ma=86400"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Customer is located outside supported countries\"\n}"},{"id":"888de373-374b-49c7-878a-d8df6f2053e6","name":"Request Kit Endpoint - Invalid Partner / Public key","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"invalid partner id\", //Required\r\n \"customer_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/kit"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"Date","value":"Wed, 17 Mar 2021 16:21:23 GMT"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"Transfer-Encoding","value":"chunked"},{"key":"Connection","value":"keep-alive"},{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"ETag","value":"W/\"c6f639ed6cc5dfa888c7fd5e1a8b57c6\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"eea95ba5-38b5-4b3f-96c3-d9f7685dc39f"},{"key":"X-Runtime","value":"0.005592"},{"key":"CF-Cache-Status","value":"DYNAMIC"},{"key":"cf-request-id","value":"08e296f6d90000ee71dc3d4000000001"},{"key":"Expect-CT","value":"max-age=604800, report-uri=\"https://report-uri.cloudflare.com/cdn-cgi/beacon/expect-ct\""},{"key":"Report-To","value":"{\"group\":\"cf-nel\",\"max_age\":604800,\"endpoints\":[{\"url\":\"https:\\/\\/a.nel.cloudflare.com\\/report?s=yl1ZxS6lgisNXL0LV21QoK80RyEVCyCtmAFDcL%2BkQSEfPhQWLMdiEK91gkbas2lMSShZKHeDpZdVD1DmnBZMp7za9KRyNLTVqCwZ1k4gJI4BmkKoGTW6\"}]}"},{"key":"NEL","value":"{\"report_to\":\"cf-nel\",\"max_age\":604800}"},{"key":"Server","value":"cloudflare"},{"key":"CF-RAY","value":"63178dd15d4fee71-CDG"},{"key":"Content-Encoding","value":"br"},{"key":"alt-svc","value":"h3-27=\":443\"; ma=86400, h3-28=\":443\"; ma=86400, h3-29=\":443\"; ma=86400"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\"\n}"},{"id":"8af7745e-6947-467c-ab0d-f46bd348eea6","name":"Request Kit Endpoint - Customer Not Found","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec1\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/kit"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"Date","value":"Wed, 17 Mar 2021 16:21:00 GMT"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"Transfer-Encoding","value":"chunked"},{"key":"Connection","value":"keep-alive"},{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"ETag","value":"W/\"3b13c279e93bf88695a1ce6c61348f7e\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"fe690d62-c828-446b-abce-34d8afb1dee9"},{"key":"X-Runtime","value":"0.007526"},{"key":"CF-Cache-Status","value":"DYNAMIC"},{"key":"cf-request-id","value":"08e2969faa0000ee71ed9f0000000001"},{"key":"Expect-CT","value":"max-age=604800, report-uri=\"https://report-uri.cloudflare.com/cdn-cgi/beacon/expect-ct\""},{"key":"Report-To","value":"{\"group\":\"cf-nel\",\"max_age\":604800,\"endpoints\":[{\"url\":\"https:\\/\\/a.nel.cloudflare.com\\/report?s=2JomaV0FQaGX%2BPuv658VihLccTQ0faHNowZbb1KqBy9xT8wchlSMnfRmbegxU1zCQNHCh%2Fc%2Bk4IvNSLuQBZN9GoIhZ4cujzGDaet0vMgBxvL28B2dHgg\"}]}"},{"key":"NEL","value":"{\"report_to\":\"cf-nel\",\"max_age\":604800}"},{"key":"Server","value":"cloudflare"},{"key":"CF-RAY","value":"63178d45dbe0ee71-CDG"},{"key":"Content-Encoding","value":"br"},{"key":"alt-svc","value":"h3-27=\":443\"; ma=86400, h3-28=\":443\"; ma=86400, h3-29=\":443\"; ma=86400"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Customer Not Found\"\n}"},{"id":"f516d1c3-5d3f-4c0c-b253-7a72564d3fdb","name":"Request Kit Endpoint - Custome Has No Shipping Address","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/kit"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"Date","value":"Wed, 17 Mar 2021 16:19:01 GMT"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"Transfer-Encoding","value":"chunked"},{"key":"Connection","value":"keep-alive"},{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"ETag","value":"W/\"9f84ed0668dc3967b50b856bdfd15e99\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"00176abd-5df8-4df6-8a98-80eb5f5e32b6"},{"key":"X-Runtime","value":"0.106281"},{"key":"CF-Cache-Status","value":"DYNAMIC"},{"key":"cf-request-id","value":"08e294cc300000ee71dcb53000000001"},{"key":"Expect-CT","value":"max-age=604800, report-uri=\"https://report-uri.cloudflare.com/cdn-cgi/beacon/expect-ct\""},{"key":"Report-To","value":"{\"group\":\"cf-nel\",\"max_age\":604800,\"endpoints\":[{\"url\":\"https:\\/\\/a.nel.cloudflare.com\\/report?s=Ml42Sc74p8lf9yYUegm%2BUVbyMsul8ERhmWjERFY1PfWTC%2FH%2BRdSmyxCZ57VjcFry540e19fNfmzQMCThE%2FDlJJZURD%2B2K4hHNAgEZXqcaCxCDHWXKqfm\"}]}"},{"key":"NEL","value":"{\"report_to\":\"cf-nel\",\"max_age\":604800}"},{"key":"Server","value":"cloudflare"},{"key":"CF-RAY","value":"63178a59eb48ee71-CDG"},{"key":"Content-Encoding","value":"br"},{"key":"alt-svc","value":"h3-27=\":443\"; ma=86400, h3-28=\":443\"; ma=86400, h3-29=\":443\"; ma=86400"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Shipping Address Not Found\"\n}"}],"_postman_id":"18485911-8bf0-464a-a09b-1532513d15c6"},{"name":"Kit Status","id":"851d77e3-e15b-4122-96bd-712c30266f02","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/kit/status","description":"

Description: This endpoint checks for customer's DNA kit status

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

","urlObject":{"path":["kit","status"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"3964a45e-f2cd-4ab5-a3fd-66e679e4293c","name":"Kit Status - Successful Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/kit/status"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"Date","value":"Wed, 17 Mar 2021 16:26:59 GMT"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"Transfer-Encoding","value":"chunked"},{"key":"Connection","value":"keep-alive"},{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"ETag","value":"W/\"9259fb3e11b3d9d50a9a4e65dc5d0a6b\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"5a291b57-8209-469b-a5f2-933939f36b4e"},{"key":"X-Runtime","value":"0.132717"},{"key":"CF-Cache-Status","value":"DYNAMIC"},{"key":"cf-request-id","value":"08e29c16ed0000ee71bfa10000000001"},{"key":"Expect-CT","value":"max-age=604800, report-uri=\"https://report-uri.cloudflare.com/cdn-cgi/beacon/expect-ct\""},{"key":"Report-To","value":"{\"group\":\"cf-nel\",\"max_age\":604800,\"endpoints\":[{\"url\":\"https:\\/\\/a.nel.cloudflare.com\\/report?s=KYacUzJglsPNkgsyKI%2BzR0x8lBE0PAgtXGBk%2B%2Fh8SmN6j%2Fu8a0rCQr%2F8OK2mJIAXcOqxF60JYaS1%2FnDhDr4yv8pSjEmKOpbmKGfYIAzCGXcdJFLr1x3v\"}]}"},{"key":"NEL","value":"{\"report_to\":\"cf-nel\",\"max_age\":604800}"},{"key":"Server","value":"cloudflare"},{"key":"CF-RAY","value":"63179604a802ee71-CDG"},{"key":"Content-Encoding","value":"br"},{"key":"alt-svc","value":"h3-27=\":443\"; ma=86400, h3-28=\":443\"; ma=86400, h3-29=\":443\"; ma=86400"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Kit Status Retrieved\",\n \"kit_status\": \"requested\"\n}"},{"id":"d7416b7f-c64c-407d-830b-13749edd6e48","name":"Kit Status - Customer Not Found","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec1\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/kit/status"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"Date","value":"Wed, 17 Mar 2021 16:27:50 GMT"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"Transfer-Encoding","value":"chunked"},{"key":"Connection","value":"keep-alive"},{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"ETag","value":"W/\"3b13c279e93bf88695a1ce6c61348f7e\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"4bdcfac1-a9e0-402e-b675-77adf60ca720"},{"key":"X-Runtime","value":"0.007882"},{"key":"CF-Cache-Status","value":"DYNAMIC"},{"key":"cf-request-id","value":"08e29cdfe90000ee71afaa1000000001"},{"key":"Expect-CT","value":"max-age=604800, report-uri=\"https://report-uri.cloudflare.com/cdn-cgi/beacon/expect-ct\""},{"key":"Report-To","value":"{\"group\":\"cf-nel\",\"max_age\":604800,\"endpoints\":[{\"url\":\"https:\\/\\/a.nel.cloudflare.com\\/report?s=txSkdC%2FxFsHSg7M083N0kCXYBw2zdS1DLxfvBC0QRBLJvVLCS1WsMcR88b%2Fr8y0XGqSFWUghV6xS%2BJp0plWIQO801ugeO3Ca0e35l5lwqMhwtre15mpu\"}]}"},{"key":"NEL","value":"{\"report_to\":\"cf-nel\",\"max_age\":604800}"},{"key":"Server","value":"cloudflare"},{"key":"CF-RAY","value":"6317974638cfee71-CDG"},{"key":"Content-Encoding","value":"br"},{"key":"alt-svc","value":"h3-27=\":443\"; ma=86400, h3-28=\":443\"; ma=86400, h3-29=\":443\"; ma=86400"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Customer Not Found\"\n}"},{"id":"e97df010-b623-4da2-b3ab-202723f94d42","name":"Kit Status - Invalid Partner / Public / Private Keys","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"invalid partner id\", //Required\r\n \"customer_id\": \"cus_2a47ba107e77_12a8f67687dd_a2b6367700ec1\" //Required\r\n \r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/kit/status"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"Date","value":"Wed, 17 Mar 2021 16:28:37 GMT"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"Transfer-Encoding","value":"chunked"},{"key":"Connection","value":"keep-alive"},{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"ETag","value":"W/\"c6f639ed6cc5dfa888c7fd5e1a8b57c6\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"d487c28c-bedd-49cf-9958-e75faed4d7a9"},{"key":"X-Runtime","value":"0.005393"},{"key":"CF-Cache-Status","value":"DYNAMIC"},{"key":"cf-request-id","value":"08e29d97b40000ee71ce0c4000000001"},{"key":"Expect-CT","value":"max-age=604800, report-uri=\"https://report-uri.cloudflare.com/cdn-cgi/beacon/expect-ct\""},{"key":"Report-To","value":"{\"group\":\"cf-nel\",\"max_age\":604800,\"endpoints\":[{\"url\":\"https:\\/\\/a.nel.cloudflare.com\\/report?s=HL5FipMunReFSk%2BE%2F8GMUBmug%2B6pDgFaWKM3uyT%2FrIQHI9yedqPpYyMG6Id4b1CuCuP94GjFT1gG8DVxHwDNe8XpgsliGv4OiyNWzvTkRcE68QOWUQT6\"}]}"},{"key":"NEL","value":"{\"report_to\":\"cf-nel\",\"max_age\":604800}"},{"key":"Server","value":"cloudflare"},{"key":"CF-RAY","value":"6317986c5b34ee71-CDG"},{"key":"Content-Encoding","value":"br"},{"key":"alt-svc","value":"h3-27=\":443\"; ma=86400, h3-28=\":443\"; ma=86400, h3-29=\":443\"; ma=86400"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\"\n}"}],"_postman_id":"851d77e3-e15b-4122-96bd-712c30266f02"}],"id":"3097e0c4-00a4-4be6-90ee-80a59c5c43a3","_postman_id":"3097e0c4-00a4-4be6-90ee-80a59c5c43a3","description":""},{"name":"Access Endpoints","item":[{"name":"Add Access","id":"af688699-99e1-4532-ae23-426b1eb53dd0","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\", //Required\r\n \"accesses\": [\"nutrition\",\"hw\"] //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/add/accesses","description":"

Description: This Endpoint adds accesses per report to the customer

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type	Notes
public_key	Required	String
partner_id	Required	String
customer_id	Required	String
accesses	Required	Array	Allowed Values [“nutrition”,”fitness”,”hw”,”pc”,”skincare”,”imv”,”disease”,”covid”,”carrier”]

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

user_accesses

Array

Access Values table:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Access Name	Value to send
Nutrition Report	nutrition
Fitness Report	fitness
Health and wellness Report	hw
Personality and cognition Report	pc
Skincare Report	skincare
Immunity And vitamins Report	imv
Disease Report	disease
COVID-19 genetic Report	covid
Carrier Report	carrier

","urlObject":{"path":["customer","add","accesses"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"24682583-dd43-47f4-9a40-6964af5bebc1","name":"Add Access - Customer Not Found Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df9841\", //Required\r\n \"accesses\": [\"nutrition\",\"hw\"] //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/add/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"5ceb95ff8e059de22e7e93a509e8589d\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"66ce3efe-507a-4f53-b2fb-fd1b4ea9c304"},{"key":"X-Runtime","value":"0.007636"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Customer Not Found\",\n \"user_accesses\": []\n}"},{"id":"4b13edd6-abbc-4a8a-b68e-08b0c7ac81c7","name":"Add Access - Missing Parameter Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\" //Required\r\n\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/add/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"b756ab9d2dc991da287b083114368cfa\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"e224724c-3c4e-41db-994e-b8527cfac840"},{"key":"X-Runtime","value":"0.003947"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Required parameter 'accesses' missing\",\n \"user_accesses\": []\n}"},{"id":"71fad0ae-007c-4263-8125-1133969591d6","name":"Add Access - Invalid Partner ID/ Public Key/ Private Key","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"invalid partner id\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\", //Required\r\n \"accesses\": [\"nutrition\",\"hw\"] //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/add/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"dd8dd5de252bfa7a7d1a45a159b32f83\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"1be39bde-80a0-4e91-98ae-3c4f041f3786"},{"key":"X-Runtime","value":"0.005602"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\",\n \"user_accesses\": []\n}"},{"id":"caf13565-3954-4191-83aa-ff65ff131356","name":"Add Access - Successful Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\", //Required\r\n \"accesses\": [\"nutrition\",\"hw\"] //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/add/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"d0e5620630cd8fdae2c883d80ecfea61\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"1244bcb6-e90e-4625-b348-07937e8045cc"},{"key":"X-Runtime","value":"0.014839"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Accesses Updated\",\n \"user_accesses\": [\n \"nutrition\",\n \"fitness\",\n \"hw\"\n ]\n}"}],"_postman_id":"af688699-99e1-4532-ae23-426b1eb53dd0"},{"name":"Remove Access","id":"39b8d698-8c69-4840-9e45-dbea5c8f8c8b","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\", //Required\r\n \"accesses\": [\"hw\"] //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/remove/accesses","description":"

Description: This Endpoint removes accesses per report from the customer

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type	Notes
public_key	Required	String
partner_id	Required	String
customer_id	Required	String
accesses	Required	Array	Allowed Values [“nutrition”,”fitness”,”hw”,”pc”,”skincare”,”imv”,”disease”,”covid”,”carrier”]

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

user_accesses

Array

Access Values table:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Access Name	Value to send
Nutrition Report	nutrition
Fitness Report	fitness
Health and wellness Report	hw
Personality and cognition Report	pc
Skincare Report	skincare
Immunity And vitamins Report	imv
Disease Report	disease
COVID-19 genetic Report	covid
Carrier Report	carrier

","urlObject":{"path":["customer","remove","accesses"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"17ae5d95-4a27-4b10-a93a-cc3f075bcd2f","name":"Remove Access - Invalid Partner ID/ Public Key","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"invalid partner id\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\", //Required\r\n \"accesses\": [\"hw\"] //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/remove/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"dd8dd5de252bfa7a7d1a45a159b32f83\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"cf42702c-af66-4dec-b207-e0899f21ff39"},{"key":"X-Runtime","value":"0.005469"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\",\n \"user_accesses\": []\n}"},{"id":"29ba5c59-875d-4be1-b8e7-c4edda3d21cf","name":"Remove Access - Missing Required Parameter","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\"\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/remove/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"b756ab9d2dc991da287b083114368cfa\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"e899ee63-2894-42ff-b92f-52b3b04d4e51"},{"key":"X-Runtime","value":"0.003949"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Required parameter 'accesses' missing\",\n \"user_accesses\": []\n}"},{"id":"3f7ddc7e-aa98-46be-a42f-9ad6ca744a4a","name":"Remove Access - Successful Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\", //Required\r\n \"accesses\": [\"hw\"] //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/remove/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"38d86b555c804bf99aef9fc1a17de249\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"979cd4f6-dedf-447a-8246-e2b19c284c07"},{"key":"X-Runtime","value":"0.017856"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Accesses Updated\",\n \"user_accesses\": [\n \"nutrition\",\n \"fitness\"\n ]\n}"},{"id":"d37a9861-17d3-405a-b0c3-cf203edb9a44","name":"Remove Access - Customer Not Found","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df9841\", //Required\r\n \"accesses\": [\"hw\"] //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/remove/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"5ceb95ff8e059de22e7e93a509e8589d\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"c7494449-c2a6-4d1d-a270-067dd36d167b"},{"key":"X-Runtime","value":"0.006983"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Customer Not Found\",\n \"user_accesses\": []\n}"}],"_postman_id":"39b8d698-8c69-4840-9e45-dbea5c8f8c8b"},{"name":"Get Accesses","id":"dadd7ae5-49ec-427e-bcef-88e39f04dcf3","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required \r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/accesses","description":"

Description: This Endpoint generates/retrieves the customer's accesses.

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

user_accesses

Array

Access Values table:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Access Name	Value to send
Nutrition Report	nutrition
Fitness Report	fitness
Health and wellness Report	hw
Personality and cognition Report	pc
Skincare Report	skincare
Immunity And vitamins Report	imv
Disease Report	disease
COVID-19 genetic Report	covid
Carrier Report	carrier

","urlObject":{"path":["customer","accesses"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"2c695c36-1e04-4f13-8801-55cfdcbddfcc","name":"Get Accesses - Customer Not Found","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required \r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"5ceb95ff8e059de22e7e93a509e8589d\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"8539cd1c-a073-4a19-bce4-8639b6a14615"},{"key":"X-Runtime","value":"0.008354"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Customer Not Found\",\n \"user_accesses\": []\n}"},{"id":"af21653d-ec7a-42ad-aeb7-040a3ec6943d","name":"Get Accesses - Missing required parameter","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required \r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"5976b56e3bc3dac8f5ae032a3bef66d6\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"a26a1440-d318-40b1-9112-9530c697239e"},{"key":"X-Runtime","value":"0.004539"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Required parameter 'customer_id' missing\",\n \"user_accesses\": []\n}"},{"id":"c2f9e288-5a7f-4cdf-848e-772716a829d2","name":"Get Accesses - Successful Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required \r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"c4b1d123063e80a46c7a1608ed88004b\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"260030a4-707a-404b-919b-1291a2aee11f"},{"key":"X-Runtime","value":"0.012054"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Accesses retrieved\",\n \"user_accesses\": [\n \"nutrition\",\n \"fitness\"\n ]\n}"},{"id":"eba53bb1-53f3-408e-a3f6-ffda094ac223","name":"Get Accesses - Invalid Partner ID/ Public Key","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required \r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/customer/accesses"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"dd8dd5de252bfa7a7d1a45a159b32f83\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"e51d329e-93fe-4f5e-a85d-c1032da426de"},{"key":"X-Runtime","value":"0.004943"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\",\n \"user_accesses\": []\n}"}],"_postman_id":"dadd7ae5-49ec-427e-bcef-88e39f04dcf3"}],"id":"c0e987ff-e0fc-434d-bee9-fcef4826148c","_postman_id":"c0e987ff-e0fc-434d-bee9-fcef4826148c","description":""},{"name":"Orders Endpoint","item":[{"name":"Create Order","id":"ef9741b5-edf6-43d3-adfc-6aadfd478cb4","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"amount\": 52122.22, //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\", //Optional\r\n \"accesses\": [\"fitness\"], //Optional\r\n \"ref_number\": \"1127712546201625\" //Optional\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/create/order","description":"

Description:This endpoint MUST be used when any order is created so our servers have a copy of this order.

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type	Notes
public_key	Required	String
partner_id	Required	String
amount	Required	float
customer_id	Optional	String
accesses	Optional	Array	Allowed Values [“nutrition”,”fitness”,”hw”,”pc”,”skincare”,”imv”,”disease”,”covid”,”carrier”]
ref_number	Optional	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

order_id

String

","urlObject":{"path":["create","order"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"0cd03222-5b7e-4578-86a0-59ee7201fa4d","name":"Create Order - Missing optional parameters response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"amount\": 521212.22 //Required\r\n\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/create/order"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"97e8a1f0f947f77e6e39e2a9c7a1d2e0\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"e515c726-6e09-4d0c-8c92-b7538192e45f"},{"key":"X-Runtime","value":"0.012980"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Order Created\",\n \"order_id\": \"order_7755a66a94c6_911c6a35b890_8aaba60b076a\"\n}"},{"id":"27f90168-12b5-4ad8-bafc-a6e2ac913ee8","name":"Create Order - Invalid Partner ID/ Public Key","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"invalid partner id\", //Required\r\n \"amount\": 52122.22, //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\", //Optional\r\n \"accesses\": [\"fitness\"] //Optional\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/create/order"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"d2a6f1e1b6437f659926688029f7d153\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"d0aa452f-743a-47aa-aeea-2e79a2e7a464"},{"key":"X-Runtime","value":"0.006310"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\",\n \"order_id\": \"\"\n}"},{"id":"945bcf57-0e7c-4537-80a9-99576eb07214","name":"Create Order - Missing Required Parameter Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\", //Optional\r\n \"accesses\": [\"fitness\"] //Optional\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/create/order"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"ff76b0e22815d43ce36cb451c0607021\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"dd12429b-00d9-451e-9ca5-65cca95a4e00"},{"key":"X-Runtime","value":"0.002966"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Required parameter 'amount' missing\",\n \"order_id\": \"\"\n}"},{"id":"fe4fab22-e5c3-4760-9cda-d4e537978918","name":"Create Order - Successful Response","originalRequest":{"method":"POST","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"amount\": 52122.22, //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\", //Optional\r\n \"accesses\": [\"fitness\"] //Optional\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/create/order"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"f5221190c6011ada0941c5f036cd9088\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"3a21e9f8-c1e8-426d-a772-2142ebe44797"},{"key":"X-Runtime","value":"0.040757"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Order Created\",\n \"order_id\": \"order_1b5845f10083_c226b34b776f_ef5b111a6478\"\n}"}],"_postman_id":"ef9741b5-edf6-43d3-adfc-6aadfd478cb4"},{"name":"Get Partners Orders","id":"54d2d4fa-5e91-4ab1-b6ab-26b5193bb547","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/partners/orders","description":"

Description:This endpoints retrives all the orders created by a certain partner order by the newest orders

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type	Notes
public_key	Required	String
partner_id	Required	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Type	Note
status	int	200 For Success 4xx for errors
message	String
total	Float
orders	JSON

","urlObject":{"path":["partners","orders"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"a7c51e82-8cac-4479-ba18-daff2f755295","name":"Get Partners Orders - Successful Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/partners/orders"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"Date","value":"Fri, 26 Mar 2021 12:04:36 GMT"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"Transfer-Encoding","value":"chunked"},{"key":"Connection","value":"keep-alive"},{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"ETag","value":"W/\"c8921c4331b94dc90adf89ba5a40f8c0\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"def18426-51a4-41e1-85fc-1683218ae699"},{"key":"X-Runtime","value":"0.069636"},{"key":"CF-Cache-Status","value":"DYNAMIC"},{"key":"cf-request-id","value":"0910051a6b000001605a908000000001"},{"key":"Expect-CT","value":"max-age=604800, report-uri=\"https://report-uri.cloudflare.com/cdn-cgi/beacon/expect-ct\""},{"key":"Report-To","value":"{\"group\":\"cf-nel\",\"max_age\":604800,\"endpoints\":[{\"url\":\"https:\\/\\/a.nel.cloudflare.com\\/report?s=gHhy%2F2sFtEIlL%2B2%2Br%2FTdzTBLHpwUjAWoQ7fFeVibdUqct%2B5Xz4gxl9M6wYZz%2BO01L7iADbr6Pv0Ev50MBxqtS%2FYjAlkbOxLQQA%2Fqq0srtHloKm86HxYc\"}]}"},{"key":"NEL","value":"{\"report_to\":\"cf-nel\",\"max_age\":604800}"},{"key":"Server","value":"cloudflare"},{"key":"CF-RAY","value":"63603e0a4c870160-CDG"},{"key":"Content-Encoding","value":"br"},{"key":"alt-svc","value":"h3-27=\":443\"; 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Description: This Endpoint generates/retrieves the latest nutrition report for any customer

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

report_json

JSON

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This means your body can metabolize carbohydrates and regulate blood sugar level quickly. However, a healthy number of total calories and a balanced diet are important for everyone.\",\n \"risk_management\": \"Your ability to metabolize carbs is better than most people's. Congrats! You can safely enjoy more carb-rich food, such as pasta, pizza, bread, and candy without experiencing negative side effects.\\n\\nWhole grains, such as whole-grain bread or oatmeal, and other less processed sources of carbohydrates, are generally preferred because they contain more vitamins and minerals. A fasting blood sugar (FBS) test is one of the commonly used tools in checking your overall carbohydrate sensitivity. Make sure that you consult your physician before using any tests or drugs. \",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*Great news! You can eat more carbs than most people. Just focus on whole grains, such as whole-grain bread or oatmeal, and other minimally processed sources of carbohydrates.\",\n \"*Maintain a balanced diet by consuming 55% of your total calories coming from carbs. (On a 2,000 calorie diet, that's about 275g carbs.)\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"These genes tell you if your carbohydrate consumption can quickly cause excess weight gain, and eventually lead to detrimental diseases such as diabetes and hypertension.\",\n \"about\": \"Carbohydrates are the major source of energy for the body. While protein can be used to build muscle, and fats are important for many organs, including your brain and heart, the primary purpose of carbs is to provide energy. \\n\\nWe tend to put all carbs in the same category, but there's a big difference in the way they're metabolized by your body. \\n\\nSimple carbohydrates are essentially broken down before they reach your body, so they're digested and processed faster. This includes table sugar, white bread, or pasta, and they're generally less healthy for you than complex carbs.\\n\\nComplex carbohydrates are digested more slowly. When carbs are digested, they're turned to sugar in your blood. Having high blood sugar levels is dangerous to your health, so complex carbs are better for your body than simple carbs.\",\n \"caption\": \"Do you metabolize carbs quickly?\",\n \"refreances\": [\n \"1. Ruchat, S. M., Rankinen, T., Weisnagel, S. J., Rice, T., Rao, D. C., Bergman, R. N., Bouchard, C., & Pérusse, L. (2009). Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study. Diabetologia, 53(4), 679–689. https://doi.org/10.1007/s00125-009-1630-2\",\n \"2. Casas-Agustench, P., Arnett, D. K., Smith, C. E., Lai, C.-Q., Parnell, L. D., Borecki, I. B., Frazier-Wood, A. C., Allison, M., Chen, Y.-D. I., Taylor, K. D., Rich, S. S., Rotter, J. I., Lee, Y.-C., & Ordovás, J. M. (2014). Saturated fat intake modulates the association between an obesity genetic risk score and BMI in two US populations. Journal of the Academy of Nutrition and Dietetics, 114(12), 1954–1966. https://doi.org/10.1016/j.jand.2014.03.014\",\n \"3. Kwok, M. K., Leung, G. M., & Schooling, C. M. (2016). Habitual coffee consumption and risk of type 2 diabetes, ischemic heart disease, depression and Alzheimer’s disease: a Mendelian randomization study. Scientific Reports, 6(36500), 2–3. https://doi.org/10.1038/srep36500\",\n \"4. Zeggini, E., Weedon, M. N., Lindgren, C. M., Frayling, T. M., Elliott, K. S., Lango, H., Timpson, N. J., Perry, J. R. B., Rayner, N. W., Freathy, R. M., Barrett, J. C., Shields, B., Morris, A. P., Ellard, S., Groves, C. J., Harries, L. W., Marchini, J. L., Owen, K. R., Knight, B., … Hattersley, A. T. (2007). Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes. Science, 316(5829), 1336–1341. https://doi.org/10.1126/science.1142364\",\n \"5. Zhang, H., Wu, J., & Yu, L. (2014). Association of Gln27Glu and Arg16Gly Polymorphisms in Beta2-Adrenergic Receptor Gene with Obesity Susceptibility: A Meta-Analysis. PLoS ONE, 9(6), e100489. https://doi.org/10.1371/journal.pone.0100489\",\n \"6. Tanaka, T., Ngwa, J. S., van Rooij, F. J. A., Zillikens, M. C., Wojczynski, M. K., Frazier-Wood, A. C., Houston, D. K., Kanoni, S., Lemaitre, R. N., Luan, J., Mikkilä, V., Renstrom, F., Sonestedt, E., Zhao, J. H., Chu, A. Y., Qi, L., Chasman, D. I., de Oliveira Otto, M. C., Dhurandhar, E. J., … Nettleton, J. A. (2013). Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. The American Journal of Clinical Nutrition, 97, 1395–1402. https://doi.org/10.3945/ajcn.112.052183\"\n ],\n \"GENES\": {\n \"PPARG\": {\n \"rs1801282\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"TCF7L2\": {\n \"rs12255372\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"ADRB2\": {\n \"rs1042714\": {\n \"genotype\": \"GC\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Saturated fat metabolism\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Intermediate\",\n \"result_description\": \"Your result is correlated with a intermediate fat metabolism. The genes we've analyzed here affect how your body metabolizes fat, especially when it comes to saturated fats. Your result indicates a typical response to fats.\",\n \"risk_management\": \"You may not gain too much excess weight in response to fats, but saturated fats, like those found in animal products, can still be dangerous. Instead, enjoy more natural plant-based fats, and avoid processed foods.\",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*Fats are less likely to cause excess weight gain for you.\",\n \"*You may follow the recommended fat intake of 30% of total calories (roughly 50 grams of fat per day if you eat 2,000 calories a day).\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Your genetics predisposition on how you metabolize saturated fats can greatly influence how you will manage your risk to many diseases such as obesity, diabetes, and cardiovascular diseases.\",\n \"about\": \"Fat is an important part of your diet. Healthy fats provide critical benefits to your heart, brain, and more. Your genetics influence how your body responds to fats. Your body also has a unique response to saturated fats in particular. A diet high in saturated fats is linked to many health risks, including heart disease, obesity, and diabetes. However, some people may be more sensitive to saturated fats, increasing the risk of excess weight gain. You may also have a low sensitivity to the flavor of saturated fats, which can cause you to seek out more fats in your diet to achieve the same level of satisfaction.\",\n \"caption\": \"How fast do you metabolize saturated fats?\",\n \"refreances\": [\n \"1. Zhang, H., Wu, J., & Yu, L. (2014b). Association of Gln27Glu and Arg16Gly Polymorphisms in Beta2-Adrenergic Receptor Gene with Obesity Susceptibility: A Meta-Analysis. PLoS ONE, 9(6), e100489. https://doi.org/10.1371/journal.pone.0100489\",\n \"2. Cruz, M., Valladares-Salgado, A., Garcia-Mena, J., Ross, K., Edwards, M., Angeles-Martinez, J., Ortega-Camarillo, C., Escobedo de la Peña, J., Burguete-Garcia, A. I., Wacher-Rodarte, N., Ambriz, R., Rivera, R., D’artote, A. L., Peralta, J., Parra, E. J., & Kumate, J. (2010). Candidate gene association study conditioning on individual ancestry in patients with type 2 diabetes and metabolic syndrome from Mexico City. Diabetes Metabolism Research and Reviews, 26(4), 261–270. https://doi.org/10.1002/dmrr.1082\",\n \"3. Qiu, C.-J., Ye, X.-Z., Yu, X.-J., Peng, X.-R., & Li, T.-H. (2014). Association between FABP2 Ala54Thr polymorphisms and type 2 diabetes mellitus risk: a HuGE Review and Meta-Analysis. Journal of Cellular and Molecular Medicine, 18(12), 2530–2535. https://doi.org/10.1111/jcmm.12385\",\n \"4. Jääskeläinen, T., Paananen, J., Lindström, J., Eriksson, J. G., Tuomilehto, J., & Uusitupa, M. (2013). Genetic predisposition to obesity and lifestyle factors – the combined analyses of twenty-six known BMI- and fourteen known waist:hip ratio (WHR)-associated variants in the Finnish Diabetes Prevention Study. British Journal of Nutrition, 110, 1856–1865. https://doi.org/10.1017/s0007114513001116\",\n \"5. Ruchat, S.-M., Rankinen, T., Weisnagel, S. J., Rice, T., Rao, D. C., Bergman, R. N., Bouchard, C., & Pérusse, L. (2009). Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study. Diabetologia, 53(4), 679–689. https://doi.org/10.1007/s00125-009-1630-2\",\n \"6. Huertas-Vazquez, A., Plaisier, C., Weissglas-Volkov, D., Sinsheimer, J., Canizales-Quinteros, S., Cruz-Bautista, I., Nikkola, E., Herrera-Hernandez, M., Davila-Cervantes, A., Tusie-Luna, T., Taskinen, M.-R., Aguilar-Salinas, C., & Pajukanta, P. (2007). TCF7L2 is associated with high serum triacylglycerol and differentially expressed in adipose tissue in families with familial combined hyperlipidaemia. Diabetologia, 51(1), 62–69. https://doi.org/10.1007/s00125-007-0850-6\",\n \"7. Esfahini, F. H., Mirmiran, P., Daneshpour, M. S., Mottaghi, A., & Azizi, F. (2017). The Effect of Interactions of Single Nucleotide Polymorphisms of APOA1/APOC3 with Food Group Intakes on the Risk of Metabolic Syndrome. Avicenna Journal of Medical Biotechnology, 9(2), 94–103. \",\n \"8. Shatwan, I. M., Weech, M., Jackson, K. G., Lovegrove, J. A., & Vimaleswaran, K. S. (2017). Apolipoprotein E gene polymorphism modifies fasting total cholesterol concentrations in response to replacement of dietary saturated with monounsaturated fatty acids in adults at moderate cardiovascular disease risk. Lipids in Health and Disease, 16, 222. https://doi.org/10.1186/s12944-017-0606-3\",\n \"9. Lu, Y., Dollé, M. E. T., Imholz, S., van ’t Slot, R., Verschuren, W. M. M., Wijmenga, C., Feskens, E. J. M., & Boer, J. M. A. (2008). Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. Journal of Lipid Research, 49, 2582–2589. https://doi.org/10.1194/jlr.m800232-jlr200\",\n \"10. Moleres, A., Milagro, F. I., Marcos, A., Zorzano, E. G., Campoy, C., Garagorri, J. M., Sanjulian, M. C. A., Martinez, J. A., & Marti, A. (2014). Common variants in genes related to lipid and energy metabolism are associated with weight loss after an intervention in overweight/obese adolescents. Nutricion Hospitalaria, 30(1), 75–83. https://doi.org/10.3305/nh.2014.30.1.7542\",\n \"11. Tanaka, T., Ngwa, J. S., van Rooij, F. J. A., Zillikens, M. C., Wojczynski, M. K., Frazier-Wood, A. C., Houston, D. K., Kanoni, S., Lemaitre, R. N., Luan, J., Mikkilä, V., Renstrom, F., Sonestedt, E., Zhao, J. H., Chu, A. Y., Qi, L., Chasman, D. I., de Oliveira Otto, M. C., Dhurandhar, E. J., … Nettleton, J. A. (2013b). Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. The American Journal of Clinical Nutrition, 97, 1395–1402. https://doi.org/10.3945/ajcn.112.052183\"\n ],\n \"GENES\": {\n \"ADRB2\": {\n \"rs1042714\": {\n \"genotype\": \"GC\",\n \"effect_allels\": 1\n }\n },\n \"ADRB3\": {\n \"rs4994\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"FABP2\": {\n \"rs1799883\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"FTO\": {\n \"rs9939609\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"PPARG\": {\n \"rs1801282\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"TCF7L2\": {\n \"rs12255372\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LPL\": {\n \"rs328\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"APOA5\": {\n \"rs662799\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Weight change\": {\n \"result_options\": [\n \"Weight loss\",\n \"Normal weight\",\n \"Weight gain\"\n ],\n \"result\": \"Normal weight\",\n \"result_description\": \"Your genes are associated with a normal weight or BMI (body mass index). \",\n \"risk_management\": \"Although your genes suggest that it is easier for you to maintain weight, it's still important to observe a healthy eating pattern and regular diet in order to prevent lifestyle-related health problems.\\n\\nA low body weight is not always a sign of good health. Regular exercise is important for everyone, and it can improve your cognition, creative thinking, and mental health. \",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*Take precaution by maintaining a healthy diet and regular exercise.\",\n \"*If you are overweight, start with a reduction of 300-500 calories per day from your usual intake, and performing at least 20 minutes of brisk walking and jogging everyday. \"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"The strength of the genetic influence on weight disorders varies quite a bit from person to person. Research suggests that for some people, genes account for just 25% of their predisposition to be overweight, while for others, the genetic influence is as high as 70% to 80%. Having a rough idea of how large a role genes play in your weight may be helpful in terms of managing your weight.\",\n \"about\": \"Your weight depends on the number of calories you consume, how many of those calories you store, and how many you burn up. But each of these factors is influenced by a combination of genes and environment. Both can affect your physiology (such as how fast you burn calories) as well as your behavior (the types of foods you choose to eat, for instance). The interplay between all these factors begins at the moment of your conception and continues throughout your life.\\n\\nTo date, more than 400 different genes have been implicated in the causes of being overweight or obese, although only a handful appear to be major players. Genes contribute to the causes of obesity in many ways, by affecting appetite, satiety (the sense of fullness), metabolism, food cravings, body-fat distribution, and the tendency to use eating as a way to cope with stress.\",\n \"caption\": \"The genetic impact on your weight.\",\n \"refreances\": [\n \"1. Frayling, T. M., Timpson, N. J., Weedon, M. N., Zeggini, E., Freathy, R. M., Lindgren, C. M., Perry, J. R. B., Elliott, K. S., Lango, H., Rayner, N. W., Shields, B., Harries, L. W., Barrett, J. C., Ellard, S., Groves, C. J., Knight, B., Patch, A.-M., Ness, A. R., Ebrahim, S., … McCarthy, M. I. (2007). A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity. Science, 316(5826), 889–894. https://doi.org/10.1126/science.1141634\",\n \"2. Smith, C. E., Tucker, K. L., Arnett, D. K., Noel, S. E., Corella, D., Borecki, I. B., Feitosa, M. F., Aslibekyan, S., Parnell, L. D., Lai, C.-Q., Lee, Y.-C., & Ordovás, J. M. (2013). Apolipoprotein A2 Polymorphism Interacts with Intakes of Dairy Foods to Influence Body Weight in 2 U.S. Populations. The Journal of Nutrition, 143(12), 1865–1871. https://doi.org/10.3945/jn.113.179051\",\n \"3. Park, S., Kim, D. S., & Kang, S. (2018). Carrying minor allele of FADS1 and haplotype of FADS1 and FADS2 increased the risk of metabolic syndrome and moderate but not low fat diets lowered the risk in two Korean cohorts. European Journal of Nutrition, 58(2), 831–842. https://doi.org/10.1007/s00394-018-1719-9\",\n \"4. Luan, J., Kerner, B., Zhao, J.-H., Loos, R. J. F., Sharp, S. J., Muthén, B. O., & Wareham, N. J. (2009). A multilevel linear mixed model of the association between candidate genes and weight and body mass index using the Framingham longitudinal family data. BMC Proceedings, 3(S7), S115. https://doi.org/10.1186/1753-6561-3-s7-s115\",\n \"5. Willer, C. J., Speliotes, E. K., Loos, R. J. F., Li, S., Lindgren, C. M., Heid, I. M., Berndt, S. I., Elliott, A. L., Jackson, A. U., Lamina, C., Lettre, G., Lim, N., Lyon, H. N., McCarroll, S. A., Papadakis, K., Qi, L., Randall, J. C., Roccasecca, R. M., Sanna, S., ... Hirschhorn, J. N. (2008). Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genetics, 41(1), 25–34. https://doi.org/10.1038/ng.287\",\n \"6. Goni, L., Sun, D., Heianza, Y., Wang, T., Huang, T., Martínez, J. A., Shang, X., Bray, G. A., Smith, S. R., Sacks, F. M., & Qi, L. (2018). A circadian rhythm-related MTNR1B genetic variant modulates the effect of weight-loss diets on changes in adiposity and body composition: the POUNDS Lost trial. European Journal of Nutrition, 58(4), 1381–1389. https://doi.org/10.1007/s00394-018-1660-y\",\n \"7. Pirini, F., Rodriguez Torres, S., Ayandibu, B., Orera Clemente, M., Gonzalez de la Vega, A., Lawson, F., Thorpe, R., Sidransky, D., & Guerrero Preston, R. (2018). INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program. Molecular Medicine Reports, 17(1), 1699–1709. https://doi.org/10.3892/mmr.2017.8039\",\n \"8. Teng, A. C. T., Adamo, K., Tesson, F., & Stewart, A. F. R. (2009). Functional characterization of a promoter polymorphism that drives ACSL5 gene expression in skeletal muscle and associates with diet‐induced weight loss. The FASEB Journal, 23(6), 1705–1709. https://doi.org/10.1096/fj.08-120998\",\n \"9. Haupt, A., Thamer, C., Heni, M., Ketterer, C., Machann, J., Schick, F., Machicao, F., Stefan, N., Claussen, C. D., Haring, H.-U., Fritsche, A., & Staiger, H. (2009). Gene Variants of TCF7L2 Influence Weight Loss and Body Composition During Lifestyle Intervention in a Population at Risk for Type 2 Diabetes. Diabetes, 59(3), 747–750. https://doi.org/10.2337/db09-1050\",\n \"10. Aller, E. E. J. G., Mariman, E. C. M., Bouwman, F. G., & van Baak, M. A. (2017). Genetic Predictors of ≥5% Weight Loss by Multidisciplinary Advice to Severely Obese Subjects. Journal of Nutrigenetics and Nutrigenomics, 10(1–2), 32–42. https://doi.org/10.1159/000469662\"\n ],\n \"GENES\": {\n \"FTO\": {\n \"rs9939609\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"APOA2\": {\n \"rs5082\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"FADS1\": {\n \"rs174547\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"MC4R\": {\n \"rs17782313\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"MC4R@DUB526\": {\n \"rs17773235\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"TMEM18\": {\n \"rs6548238\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"SH2B1\": {\n \"rs4788102\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"MTCH2\": {\n \"rs10838738\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"KCTD15\": {\n \"rs11084753\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"MTNR1B\": {\n \"rs10830963\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"INSIG2\": {\n \"rs17047697\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"ACSL5\": {\n \"rs2419621\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"TCF7L2\": {\n \"rs7903146\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"PPARG\": {\n \"rs1801282\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Sodium sensitivity\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Intermediate\",\n \"result_description\": \"Your result is correlated with a normal genetic sensitivity to salt; you may not experience as many health problems in response to consuming salt, like high blood pressure. \",\n \"risk_management\": \"Although your result says that you have normal sensitivity to salt, it's still best to limit your sodium intake to 2.0 g per day, which is relatively easy: it would take 10 orders of medium french fries at a fast food restaurant to hit that number. (Unfortunately, it takes just 10 or 12 slices of bacon to break that limit.) \\n\\nYou can remove the salt while cooking and use herbs and spices, like cumin, cayenne, paprika, black pepper, oregano, garlic, and onion, to improve the taste of food without increasing sodium intake. Citrus, such as lemon juice, can also be a great way to add that \\\"zing\\\" without using salt.\",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*While you are not sensitive to salt, it is recommended that you limit your sodium intake to 2.0 g per day (to give you an idea, that's about 10 slices of bacon).\",\n \"*Keep your food delicious with herbs, spices, or citrus juices instead of salt.\"\n ],\n \"star_rating\": 2,\n \"snp_table_caption\": \"These genes determine how much salt may increase your blood pressure. This report can also reveal how much your blood pressure may improve in the absence of salt or through the use of diuretics, a type of drug used to improve blood pressure and heart health.\",\n \"about\": \"Salt is commonly used to add flavor to virtually all food. \\n\\nUnfortunately, salt may increase your blood pressure. Some people are genetically prone to have a greater increase in blood pressure in response to consuming salt.\\n\\nSalt sensitivity of blood pressure (BP) refers to how your blood pressure changes in response to salt intake. The underlying mechanisms that promote salt sensitivity are complex and range from genetic to environmental influences. The phenotype of salt sensitivity is heterogeneous, with multiple mechanisms that potentially link high salt intake to increases in blood pressure. Moreover, excess salt intake has functional and pathological effects on the vasculature that are independent of blood pressure (meaning that excess salt may damage your health even if you don't have high blood pressure). \",\n \"caption\": \"Salt and your blood pressure.\",\n \"refreances\": [\n \"1. Chung, C.-M., Wang, R.-Y., Chen, J.-W., Fann, C. S. J., Leu, H.-B., Ho, H.-Y., Ting, C.-T., Lin, T.-H., Sheu, S.-H., Tsai, W.-C., Chen, J.-H., Jong, Y.-S., Lin, S.-J., Chen, Y.-T., & Pan, W.-H. (2010). A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor. The Pharmacogenomics Journal, 10, 537–544. https://doi.org/10.1038/tpj.2009.70\",\n \"2. Carey, R. M., Schoeffel, C. D., Gildea, J. J., Jones, J. E., McGrath, H. E., Gordon, L. N., Park, M. J., Sobota, R. S., Underwood, P. C., Williams, J., Sun, B., Raby, B., Lasky-Su, J., Hopkins, P. N., Adler, G. K., Williams, S. M., Jose, P. A., & Felder, R. A. (2012). Salt Sensitivity of Blood Pressure Is Associated With Polymorphisms in the Sodium-Bicarbonate Cotransporter. Hypertension, 60(5), 1359–1366. https://doi.org/10.1161/hypertensionaha.112.196071\",\n \"3. Wang, R., Zhong, B., Liu, Y., & Wang, C. (2010). Association between a-adducin gene polymorphism (Gly460Trp) and genetic predisposition to salt sensitivity: a meta-analysis. Journal of Applied Genetics, 51, 87–94. https://doi.org/10.1007/bf03195715\"\n ],\n \"GENES\": {\n \"ACE\": {\n \"rs4343\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"ADD1\": {\n \"rs4961\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Fiber need\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your result is correlated with a low fiber need. \",\n \"risk_management\": \"Fiber is typically higher in fruits and vegetables (leafy greens). According to the Institute of Medicine, your daily dietary fiber intake may be as low as 10 grams. Eating high-fiber meals is commonly beneficial to your digestion and bowel movements; however, since your results identified low need for fiber, a low-fiber diet is sufficient to bring good results to your body.\",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*Maintain a low-fiber diet by consuming a minimum of 10-15 grams assuming a 2,000 daily calorie diet.\",\n \"*Consult your nutritionist or dietitian for suitable low-fiber meals.\"\n ],\n \"star_rating\": 2,\n \"snp_table_caption\": \"\\nThe risk of developing various conditions, such as diabetes and gastrointestinal diseases are associated with lifestyle and dietary factors. Being aware of your fiber intake may help you avoid these various conditions.\\n\\n\",\n \"about\": \"Dietary fiber is material from plant cells that cannot be broken down by enzymes in the human digestive tract. There are two important types of fiber: water-soluble and water-insoluble. Each has different properties and characteristics. Both are healthy parts of a normal diet.\\n\\nSoluble — Water-soluble fibers absorb water during digestion. They increase stool bulk and may decrease blood cholesterol levels. Soluble fiber can be found in fruits (such as apples, oranges, and grapefruit), vegetables, legumes (such as dry beans, lentils and peas), barley, oats, and oat bran.\\nInsoluble — Water-insoluble fibers remain unchanged during digestion. They promote the normal movement of intestinal contents. Insoluble fiber can be found in fruits with edible peels or seeds, vegetables, whole grain products (such as whole-wheat bread, pasta, and crackers), bulgur wheat, stone-ground cornmeal, cereals, bran, rolled oats, buckwheat, and brown rice.\",\n \"caption\": \"Should you eat more fiber?\",\n \"refreances\": [\n \"1. Steemburgo, T., Azevedo, M. J., Gross, J. L., Milagro, F. I., Campión, J., & Martínez, J. A. (2013). The rs9939609 Polymorphism in theFTOGene Is Associated with Fat and Fiber Intakes in Patients with Type 2 Diabetes. Journal of Nutrigenetics and Nutrigenomics, 6(2), 97–106. https://doi.org/10.1159/000350741\",\n \"2. Barrett, J. C., Hansoul, S., Nicolae, D. L., Cho, J. H., Duerr, R. H., Rioux, J. D., Brant, S. R., Silverberg, M. S., Taylor, K. D., Barmada, M. M., Bitton, A., Dassopoulos, T., Datta, L. W., Green, T., Griffiths, A. M., Kistner, E. O., Murtha, M. T., Regueiro, M. D., Rotter, J. I., … Daly, M. J. (2008). Genome-wide association defines more than 30 distinct susceptibility loci for Crohn’s disease. Nature Genetics, 40, 955–962. https://doi.org/10.1038/ng.175\",\n \"3. Tarabra, E., Actis, G. C., Fadda, M., De Paolis, P., Comandone, A., Coda, R., & Rosina, F. (2012). The obesity gene and colorectal cancer risk: A population study in Northern Italy. European Journal of Internal Medicine, 23(1), 65–69. https://doi.org/10.1016/j.ejim.2011.07.011\"\n ],\n \"GENES\": {\n \"FTO\": {\n \"rs9939609\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"SBNO2\": {\n \"rs4807569\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Gluten sensitivity\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your result is correlated with low sensitivity to gluten. Gluten is not likely to cause health problems for you.\",\n \"risk_management\": \"Gluten, a protein found in wheat, is incredibly useful to people on a vegan diet, as it provides a large source of healthy proteins. Sensitivity to gluten can be triggered by several factors such as surgery, pregnancy, childbirth, viral infections, and severe emotional stress. Your low sensitivity to gluten allows you to consume food without allergic reactions to it in a healthy, well balanced diet. \\n\\nThe foods that are rich in gluten include barley, farina, graham flour, flour starch, kasha, millet, buckwheat, rye, wheat germs and wheat starch, malt (a derivative of barley), and other hidden gluten in flavorings or poultry and meat products, HVP, emulsifiers, and stabilizers. Breaded chicken, for example, has gluten, though you might not expect it.\",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*This is great! You are able to eat a healthy and balanced meal that has gluten without experiencing negative effects.\",\n \"*You may eat more cereal grains, such as wheat, rye, and triticale, that are rich in gluten.\"\n ],\n \"star_rating\": 2,\n \"snp_table_caption\": \"\\nSince gluten sensitivity is highly relevant to food allergies, we have analyzed genetic variants that are correlated with allergenic reactions. HLA-DQ7 gene is an HLA-DQ serotype that recognizes the common HLA DQB1*0301 and the less common HLA DQB1*0304 gene products. DQ7 is a form of 'split antigen' of the broad antigen group DQ3 which also contains DQ8 and DQ9. This has been shown to be associated with non-celiac gluten sensitive individuals. The myosin IXB (MYO9B) encodes an unconventional myosin molecule that is involved in intracellular movements. Genetic variation of MYO9B gene may result in an impairment of the intestinal barrier and contribute to the pathogenesis of certain autoimmune diseases including gluten intolerance. \\n\\nThis test does not cover all possible variants associated with gluten sensitivity.\",\n \"about\": \"Gluten sensitivity is a fairly common problem especially in the US population. It is characterized by adverse reactions to gluten, a protein found in wheat, barley, and rye.\\n\\nAlso known as gluten intolerance, it has different forms. Celiac disease being the most severe form. It is an autoimmune disease that affects about 1% of the population and may lead to damage in the digestive system. However, anywhere from 0.5% to 13% of the population may also have non-celiac gluten sensitivity, a milder form of gluten intolerance that can still cause health problems.\\n\\nBoth forms of gluten intolerance can cause widespread symptoms throughout the body, many of which have nothing to do with digestion.\",\n \"caption\": \"Should you go gluten-free?\",\n \"refreances\": [\n \"1. Dubois, P. C. A., Trynka, G., Franke, L., Hunt, K. A., Romanos, J., Curtotti, A., Zhernakova, A., Heap, G. A. R., Ádány, R., Aromaa, A., Bardella, M. T., van den Berg, L. H., Bockett, N. A., de la Concha, E. G., Dema, B., Fehrmann, R. S. N., Fernández-Arquero, M., Fiatal, S., Grandone, E., … van Heel, D. A. (2010). Multiple common variants for celiac disease influencing immune gene expression. Nature Genetics, 42, 295–302. https://doi.org/10.1038/ng.543\",\n \"2. Monsuur, A. J., de Bakker, P. I. W., Zhernakova, A., Pinto, D., Verduijn, W., Romanos, J., Auricchio, R., Lopez, A., van Heel, D. A., Crusius, J. B. A., & Wijmenga, C. (2008). Effective Detection of Human Leukocyte Antigen Risk Alleles in Celiac Disease Using Tag Single Nucleotide Polymorphisms. PLoS ONE, 4(5). https://doi.org/10.1371/journal.pone.0002270\",\n \"3. Pisapia, L., Camarca, A., Picascia, S., Bassi, V., Barba, P., Del Pozzo, G., & Gianfrani, C. (2016). HLA-DQ2.5 genes associated with celiac disease risk are preferentially expressed with respect to non-predisposing HLA genes: Implication for anti-gluten T cell response. Journal of Autoimmunity, 70, 63–72. https://doi.org/10.1016/j.jaut.2016.03.016\"\n ],\n \"GENES\": {\n \"HLA-DQA1\": {\n \"rs2187668\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HLA-DQ8\": {\n \"rs7454108\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"MYO9B\": {\n \"rs2305764\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Lactose tolerance\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"High\",\n \"result_description\": \"Your result show that you have high lactose tolerance.\",\n \"risk_management\": \"You may consume dairy (lactose) with minimal problems. Your body should make enough of the enzyme \\\"Lactase\\\" to metabolize lactose, the main sugar in dairy products. However, in some circumstances, lactose intolerance can develop without a genetic component; characterized as acquired or \\\"secondary,\\\" this can happen after an illness, injury, or surgery involving your small intestines, such as celiac disease, bacterial imbalance, and Crohn's disease. When this happens, you may take dietary supplements containing Lactase, available in tablets or capsules, if you want to enjoy dairy products while minimizing the uncomfortable side effects. Milk has a high amount of lactose, whereas certain cheeses, especially aged cheeses, have much less lactose. Cheese may be a less harmful way to enjoy the flavors you love. Also, note that dairy products with high-fat content (such as whole milk) are usually better tolerated. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Lactose intolerance is commonly undiagnosed, especially for those experiencing mild symptoms. It is important that once you suspect having this condition, a validation from your physician is obtained in order to address this issue (and for you to be able to enjoy food without compromising your health). \\n\\nThis test does not cover all possible variants associated with lactose tolerance.\",\n \"about\": \"Lactose is a type of carbohydrate from dairy milk. It is often added to processed foods for flavor, but milk and foods derived from it, such as fresh cheese or ice cream, generally contain the highest amounts.\\n\\nNaturally, our ancestors would only have consumed milk as infants. We are the only species to consume the milk of another animal as adults, so difficulty digesting dairy is extremely common.\\n\\nFor people who consume dairy with genetic lactose sensitivity, there may be excess gas, pain, and digestive problems.\",\n \"caption\": \"Avoid painful side effects from lactose (dairy).\",\n \"refreances\": [\n \"1. Kettunen, J., Silander, K., Saarela, O., Amin, N., Muller, M., Timpson, N., Surakka, I., Ripatti, S., Laitinen, J., Hartikainen, A.-L., Pouta, A., Lahermo, P., Anttila, V., Mannisto, S., Jula, A., Virtamo, J., Salomaa, V., Lehtimaki, T., Raitakari, O., … Peltonen, L. (2009). European lactase persistence genotype shows evidence of association with increase in body mass index. Human Molecular Genetics, 19(6), 1129–1136. https://doi.org/10.1093/hmg/ddp561\",\n \"2. Friedrich, D. C., Santos, S. E. B., Ribeiro-dos-Santos, Ã. K. C., & Hutz, M. H. (2013). Several Different Lactase Persistence Associated Alleles and High Diversity of the Lactase Gene in the Admixed Brazilian Population. PLoS ONE, 7(10), e46520. https://doi.org/10.1371/annotation/04ccbcf8-8910-43b6-8d25-b2ca0270cd84\",\n \"3. Li, M., Maruthur, N. M., Loomis, S. J., Pietzner, M., North, K. E., Mei, H., Morrison, A. C., Friedrich, N., Pankow, J. S., Nauck, M., Boerwinkle, E., Teumer, A., Selvin, E., & Köttgen, A. (2017). Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism. Scientific Reports, 7, 2812. https://doi.org/10.1038/s41598-017-02287-x\"\n ],\n \"GENES\": {\n \"MCM6/LCT\": {\n \"rs182549\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Caffeine sensitivity\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Intermediate\",\n \"result_description\": \"Your result is correlated with a normal caffeine sensitivity.\",\n \"risk_management\": \"Because of your normal sensitivity to caffeine, consuming coffee may deliver good health benefits to you, and drinking a normal amount (4 cups of coffee per day) should not cause problems for you.\",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*You should be able to drink more coffee than others, but make sure not to over-consume.\",\n \"*You can safely consume 2-4 cups of coffee per day, but avoid sugary and dangerous energy drinks.\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Caffeine sensitivity is affected in two basic ways.\\n\\nFirst, you may metabolize caffeine more slowly, which increases your sensitivity. \\n\\nSecond, caffeine may lower your bone density, depending on your genetic variations. \\n\\nWe combine these two effects to determine how much caffeine you can safely consume in a day.\",\n \"about\": \"Caffeine can have very different effects, depending on your genetics. It can sometimes improve your overall health, while other people may experience anxiety, headaches, stomach pains, or high blood pressure.\\n\\nLimiting your caffeine intake to the first part of the day can help improve your sleep patterns and restfulness.\",\n \"caption\": \"Coffee lovers: beware.\",\n \"refreances\": [\n \"1. Cornelis, M. C., Kacprowski, T., Menni, C., Gustafsson, S., Pivin, E., Adamski, J., Artati, A., Eap, C. B., Ehret, G., Friedrich, N., Ganna, A., Guessous, I., Homuth, G., Lind, L., Magnusson, P. K., Mangino, M., Pedersen, N. L., Pietzner, M., Suhre, K., … Ingelsson, E. (2016). Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Human Molecular Genetics, 25(24), 5472–5482. https://doi.org/10.1093/hmg/ddw334\",\n \"2. Cornelis, M. C., Monda, K. L., Yu, K., Paynter, N., Azzato, E. M., Bennett, S. N., Berndt, S. I., Boerwinkle, E., Chanock, S., Chatterjee, N., Couper, D., Curhan, G., Heiss, G., Hu, F. B., Hunter, D. J., Jacobs, K., Jensen, M. K., Kraft, P., Landi, M. T., … Caporaso, N. E. (2011). Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption. PLoS Genetics, 7(4), e1002033. https://doi.org/10.1371/journal.pgen.1002033\",\n \"3. Kwok, M. K., Leung, G. M., & Schooling, C. M. (2016). Habitual coffee consumption and risk of type 2 diabetes, ischemic heart disease, depression and Alzheimer’s disease: a Mendelian randomization study. Scientific Reports, 6(36500). https://doi.org/10.1038/srep36500\",\n \"4. Amin, N., Byrne, E., Johnson, J., Chenevix-Trench, G., Walter, S., Nolte, I. M., Vink, J. M., Rawal, R., Mangino, M., Teumer, A., Keers, J. C., Verwoert, G., Baumeister, S., Biffar, R., Petersmann, A., Dahmen, N., Doering, A., Isaacs, A., Broer, L., … van Duijn, C. M. (2011). Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Molecular Psychiatry, 17(11), 1116–1129. https://doi.org/10.1038/mp.2011.101\"\n ],\n \"GENES\": {\n \"AHR\": {\n \"rs4410790\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"POR\": {\n \"rs17685\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"CYP1A1/ CYP1A2\": {\n \"rs2470893\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"CPLX3/ ULK3\": {\n \"rs6495122\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n },\n \"LAMB4/ NRCAM\": {\n \"rs382140\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Protein intake\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your result is correlated with a low intake of protein-rich food. According to your genetics, you have a tendency to consume less protein compared to the general population. \",\n \"risk_management\": \"The recommended protein intake for healthy adults is 15% of the daily total calories, which is about 60 grams for women and 90 grams for men. Decreased intake of protein may be detrimental to your health in the long run because protein-rich foods such as meats, dairy products, and eggs are also rich sources of B vitamins, vitamins A and E, iron, and other essential micronutrients. The key to a good diet is eating everything in moderation, with diverse sources of protein, carbs, and fats. It is best to consult your nutritionist or doctor on the best quantity and quality of protein that your body needs. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Knowing the specific genes that may affect your protein consumption can also make it easier to manage your weight, feel full, and increase muscular health if you consume the right amount of protein that your body requires.\",\n \"about\": \"Protein is critical for many biological functions and is the source of various amino acids. Proteins (amino acids) perform various essential tasks in the body, from protection, support and even metabolism. \\n\\nHowever, some genes may cause you to eat less protein. This is because people with certain genetic variations have been found to consume less protein, which may result in certain health issues, and can make it more difficult to manage your weight.\",\n \"caption\": \"Love protein? Need some more in your diet?\",\n \"refreances\": [\n \"1. Tanaka, T., Ngwa, J. S., van Rooij, F. J. A., Zillikens, M. C., Wojczynski, M. K., Frazier-Wood, A. C., Houston, D. K., Kanoni, S., Lemaitre, R. N., Luan, J., Mikkilä, V., Renstrom, F., Sonestedt, E., Zhao, J. H., Chu, A. Y., Qi, L., Chasman, D. I., de Oliveira Otto, M. C., Dhurandhar, E. J., … Nettleton, J. A. (2013c). Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. The American Journal of Clinical Nutrition, 97(6), 1395–1402. https://doi.org/10.3945/ajcn.112.052183\",\n \"2. Chu, A. Y., Workalemahu, T., Paynter, N. P., Rose, L. M., Giulianini, F., Tanaka, T., Ngwa, J. S., Qi, Q., Curhan, G. C., Rimm, E. B., Hunter, D. J., Pasquale, L. R., Ridker, P. M., Hu, F. B., Chasman, D. I., & Qi, L. (2013). Novel locus including FGF21 is associated with dietary macronutrient intake. Human Molecular Genetics, 22(9), 1895–1902. https://doi.org/10.1093/hmg/ddt032\",\n \"3. Merino, J., Dashti, H. S., Li, S. X., Sarnowski, C., Justice, A. E., Graff, M., Papoutsakis, C., Smith, C. E., Dedoussis, G. V., Lemaitre, R. N., Wojczynski, M. K., Männistö, S., Ngwa, J. S., Kho, M., Ahluwalia, T. S., Pervjakova, N., Houston, D. K., Bouchard, C., Huang, T., … Tanaka, T. (2018). Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. Molecular Psychiatry, 24(12), 1920–1932. https://doi.org/10.1038/s41380-018-0079-4\"\n ],\n \"GENES\": {\n \"FTO\": {\n \"rs1421085\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"FGF21, FUT1\": {\n \"rs838133\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"PROXI\": {\n \"rs1440620\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Peach Allergy\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"High\",\n \"result_description\": \"Your result is correlated with a high risk of allergic reaction to peach.\",\n \"risk_management\": \"The peach allergy is a surprisingly common fruit allergy with reactions seen and recorded in more than 50% of the allergic population. However, although you have a higher susceptibility to this allergy, you can safely eat peaches in minute amounts unless a peach allergy manifests. The best test to demonstrate a reaction to peach is the skin-prick test with fresh peach. In this test, the surgical knife is plunged several times into the fruit immediately before pricking the patient’s skin with it. The frequency of positive test results in allergic patients is high, generally over 90%. The peel and pulp can be tested separately. False-negative skin tests are frequently found with commercial peach extracts, especially in patients sensitized to finicky peach allergens, which can be modified during the extract preparation. This factor can also reduce the diagnostic accuracy of commercially available blood tests.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Since this type of allergy can cause anaphylactic shock in some individuals, detection and prevention management is important. Knowing the extent or possibility of this allergy may be helpful in ensuring the best quality of life in terms of diet and lifestyle choices.\",\n \"about\": \"Like many other allergies to fresh fruits and vegetables, a peach allergy can take two different forms. In Northern Europe, people with a birch-pollen allergy can develop a peach allergy due to the similarity between the protein in birch that causes birch-pollen allergy, and a particular peach protein. This is called \\\"birch-fruit syndrome\\\" with symptoms generally appearing within 5-15 minutes after consuming raw peach. The allergen involved in this kind of allergy does not survive cooking. Therefore, people who react to this allergen can tolerate cooked peach and its juice. Individuals often develop adverse reactions to other fruits including apple, pear, apricot, cherry, melon, banana, nuts (such as hazelnut), or vegetables, such as celeriac (celery tuber) and carrot. In Mediterranean countries, people with a peach allergy do not have a birch-pollen allergy. \",\n \"caption\": \"Be prepared for potential allergy risks.\",\n \"refreances\": [\n \"1. Khor, S.-S., Morino, R., Nakazono, K., Kamitsuji, S., Akita, M., Kawajiri, M., Yamasaki, T., Kami, A., Hoshi, Y., Tada, A., Ishikawa, K., Hine, M., Kobayashi, M., Kurume, N., Kamatani, N., Tokunaga, K., & Johnson, T. A. (2018). Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR/DQ gene region. Scientific Reports, 8(1), 1069. https://doi.org/10.1038/s41598-017-18241-w\"\n ],\n \"GENES\": {\n \"HLA-DQB1\": {\n \"rs9275428\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"HLA-DQB1@DUB756\": {\n \"rs9275406\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"HLA-DQB1@DUB140\": {\n \"rs9275332\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"HLA-DQB1@DUB345\": {\n \"rs9275425\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HLA-DRB1-DQA1\": {\n \"rs532098\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Peanut Allergy\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your result is correlated with a lower risk of having a peanut allergy.\",\n \"risk_management\": \"With low risk to peanut allergy, it can be included into diet in moderation and in a balanced diet as source of protein and fats.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Since this type of allergy can cause anaphylactic shock in some individuals, detection and prevention management is important. Knowing the extent or possibility of this allergy may be helpful in ensuring the best quality of life in terms of diet and lifestyle choices.\",\n \"about\": \"Peanuts are one of the food allergens most commonly associated with anaphylaxis, a sudden and potentially deadly condition that requires immediate attention and treatment. \\n\\nThere are several misconceptions about peanut allergies. For example, a peanut is a legume (belonging to the same family as soybeans, peas, and lentils), not a tree nut. And while it was previously believed that an allergy to peanuts was lifelong, research has shown up to 20% of individuals with a peanut allergy eventually outgrow it.\",\n \"caption\": \"One of the most severe allergies.\",\n \"refreances\": [\n \"1. Hong, X., Hao, K., Ladd-Acosta, C., Hansen, K. D., Tsai, H.-J., Liu, X., Xu, X., Thornton, T. A., Caruso, D., Keet, C. A., Sun, Y., Wang, G., Luo, W., Kumar, R., Fuleihan, R., Singh, A. M., Kim, J. S., Story, R. E., Gupta, R. S., … Wang, X. (2015). Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. Nature Communications, 6, 6304. https://doi.org/10.1038/ncomms7304\"\n ],\n \"GENES\": {\n \"HLA-DRA\": {\n \"rs7192\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Shrimp Allergy\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your result is correlated with you being less likely to be allergic to shrimp. \",\n \"risk_management\": \"Allergenicity (allergic potential) to shrimp is the most common seafood allergy, and reactions to this food allergy range from mild to severe. Clinicians have developed a desensitization diet wherein this food is gradually included in the patient's daily diet for a certain period of time to let the body adapt to this allergen and eventually eradicate the allergic reaction to this food, but this strategy is dependent on the severity of the reaction: if it's too severe, this process can be dangerous.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Shrimp allergies are potentially deadly, so being aware of your allergy risk can greatly improve your health, quality of life, and mortality risk. \",\n \"about\": \"Shellfish is one of the more common food allergies. This allergy is usually lifelong, but it can begin later in life: about 60% of people with a shellfish allergy experience their first allergic reaction as adults.\\n\\nThere are two groups of shellfish: crustacea (such as shrimp, crab, and lobster) and mollusks (such as clams, mussels, oysters and scallops). Crustacea cause most shellfish allergies, and these reactions tend to be severe.\",\n \"caption\": \"A very common allergy.\",\n \"refreances\": [\n \"1. Khor, S.-S., Morino, R., Nakazono, K., Kamitsuji, S., Akita, M., Kawajiri, M., Yamasaki, T., Kami, A., Hoshi, Y., Tada, A., Ishikawa, K., Hine, M., Kobayashi, M., Kurume, N., Kamatani, N., Tokunaga, K., & Johnson, T. A. (2018b). Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR/DQ gene region. Scientific Reports, 8(1), 1069. https://doi.org/10.1038/s41598-017-18241-w\"\n ],\n \"GENES\": {\n \"HLA-DRA\": {\n \"rs2071278\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"C4A\": {\n \"rs3129924\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"NOTCH4\": {\n \"rs3830041\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HLA-DQA1, HLA-DRB1\": {\n \"rs477515\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"HLA-DQB1\": {\n \"rs7765379\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"HLA-DQB1@DUB706\": {\n \"rs13192471\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"HLA-DRB5\": {\n \"rs910049\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Antioxidant status\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Intermediate\",\n \"result_description\": \"You have a typical genetic ability to reduce free radicals, unstable molecules that can damage cells, cause illnesses, and induce premature aging.\",\n \"risk_management\": \"Free radicals are dangerous to your health. Avoiding air pollution, limiting alcohol intake, refraining from cigarettes or smoking of any kind, and avoiding industrial wastes can all help limit free radical formation in your body. We recommend you consume more fruits and vegetables, which are natural sources of antioxidants, as well as supplementing with Vitamins A, C, and E, as well as selenium, which will help your body clear out those unwanted chemicals. Here are a few natural sources of powerful antioxidants that can stabilize free radicals: kale, spinach, and carrots are rich source of Vitamin A; lemons, limes, and oranges for Vitamin C; and for Vitamin E, you can enjoy avocados, sunflower seeds, and almonds.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Antioxidant status is an important indicator of your body's response to free radicals and oxidative stress. Long-term imbalance of free radicals and antioxidants in your body can cause detrimental effects on your health. \",\n \"about\": \"Antioxidant is the collective term for different nutrients, including Vitamins A, C, and E, selenium, and other nutrients that can reduce free radicals in the body. Those free radicals can cause inflammation, heart disease, cancer, and other diseases, so healthy levels of antioxidants in your diet can truly improve your overall health and lifespan.\\n\\nThe genes in this report all affect your body's ability to process or utilize these various antioxidants. A genetic predisposition to low levels of Vitamin C, for example, may contribute to poor antioxidant levels.\",\n \"caption\": \"Should you be consuming more antioxidants?\",\n \"refreances\": [\n \"1. Wang, J., Liu, Q., Yuan, S., Xie, W., Liu, Y., Xiang, Y., Wu, N., Wu, L., Ma, X., Cai, T., Zhang, Y., Sun, Z., & Li, Y. (2017). Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies. Scientific Reports, 7, 8371. https://doi.org/10.1038/s41598-017-07737-0\",\n \"2. Xiong, Y. M., Mo, X. Y., Zou, X. Z., Song, R. X., Sun, W. Y., Lu, W., Chen, Q., Yu, Y. X., & Zang, W. J. (2010). Association study between polymorphisms in selenoprotein genes and susceptibility to Kashin-Beck disease. Osteoarthritis and Cartilage, 18(6), 817–824. https://doi.org/10.1016/j.joca.2010.02.004\",\n \"3. Mondul, A. M., Yu, K., Wheeler, W., Zhang, H., Weinstein, S. J., Major, J. M., Cornelis, M. C., Männistö, S., Hazra, A., Hsing, A. W., Jacobs, K. B., Eliassen, H., Tanaka, T., Reding, D. J., Hendrickson, S., Ferrucci, L., Virtamo, J., Hunter, D. J., Chanock, S. J., … Albanes, D. (2011). Genome-wide association study of circulating retinol levels. Human Molecular Genetics, 20(23), 4724–4731. https://doi.org/10.1093/hmg/ddr387\",\n \"4. Timpson, N. J., Forouhi, N. G., Brion, M.-J., Harbord, R. M., Cook, D. G., Johnson, P., McConnachie, A., Morris, R. W., Rodriguez, S., Luan, J., Ebrahim, S., Padmanabhan, S., Watt, G., Bruckdorfer, K. R., Wareham, N. J., Whincup, P. H., Chanock, S., Sattar, N., Lawlor, D. A., & Davey Smith, G. (2010). Genetic variation at the SLC23A1 locus is associated with circulating concentrations of l-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants. The American Journal of Clinical Nutrition, 92(2), 375–382. https://doi.org/10.3945/ajcn.2010.29438\",\n \"5. Major, J. M., Yu, K., Wheeler, W., Zhang, H., Cornelis, M. C., Wright, M. E., Yeager, M., Snyder, K., Weinstein, S. J., Mondul, A., Eliassen, H., Purdue, M., Hazra, A., McCarty, C. A., Hendrickson, S., Virtamo, J., Hunter, D., Chanock, S., Kraft, P., & Albanes, D. (2011). Genome-wide association study identifies common variants associated with circulating vitamin E levels. Human Molecular Genetics, 20(19), 3876–3883. https://doi.org/10.1093/hmg/ddr296\",\n \"6. Ferrucci, L., Perry, J. R. B., Matteini, A., Perola, M., Tanaka, T., Silander, K., Rice, N., Melzer, D., Murray, A., Cluett, C., Fried, L. P., Albanes, D., Corsi, A.-M., Cherubini, A., Guralnik, J., Bandinelli, S., Singleton, A., Virtamo, J., Walston, J., … Frayling, T. M. (2009). Common Variation in the β-Carotene 15,15′-Monooxygenase 1 Gene Affects Circulating Levels of Carotenoids: A Genome-wide Association Study. The American Journal of Human Genetics, 84(2), 123–133. https://doi.org/10.1016/j.ajhg.2008.12.019\",\n \"7. Yadav, U., Kumar, P., & Rai, V. (2018). “NQO1 Gene C609T Polymorphism (dbSNP: rs1800566) and Digestive Tract Cancer Risk: A Meta-Analysis.” Nutrition and Cancer, 70(4), 557–568. https://doi.org/10.1080/01635581.2018.1460674\"\n ],\n \"GENES\": {\n \"SOD2\": {\n \"rs4880\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"GPX1\": {\n \"rs11706370\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"RBP4, FFAR4\": {\n \"rs10882272\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"TTR\": {\n \"rs1667255\": {\n \"genotype\": \"CA\",\n \"effect_allels\": 1\n }\n },\n \"BUD13/ZNF259/APOA5\": {\n \"rs964184\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"Intergenic\": {\n \"rs12272004\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"NQO1\": {\n \"rs1800566\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Phytoestrogen need\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your result is correlated with optimal use and metabolism of phytoestrogen, which is useful in reducing the risk of cancer. \",\n \"risk_management\": \"There is probably no need to consume increased amounts of phytoestrogen from soy-based foods. However, your risks may be modified by other factors triggering cancer development. \\n\\nA family history of disease development is also a strong risk factor. Consuming soy, tofu, hummus dip, or black beans in higher amounts can help provide your body with the cancer-fighting phytoestrogen. It is also available in supplement form. Genistein is an isoflavone phytoestrogen from soy that shows anti-tumor activities in cancers.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"A common myth in the fitness world is that phytoestrogens, found in soybeans and soy-based products like tofu or tempeh, can harm your body.\\n\\nIn reality, phytoestrogens lower your risk of cancer, and they're often found in foods that improve your overall health by providing plenty of plant-based protein, vitamins, and minerals.\\n\\nThe genes in this report determine your body's decreased risk for cancer in response to the intake of phytoestrogen.\",\n \"about\": \"Myths about phytoestrogen have been spread over the last few years, but phytoestrogen is not only healthy and safe, but can also provide an extra defense against cancer.\\n\\nPhytoestrogens are compounds that naturally occur in plants. They're also found in a wide range of plant foods. If you eat fruits, veggies, legumes, and some grains, you get phytoestrogens from your diet. A plant-based diet is very rich in natural phytoestrogens in healthy amounts, especially from soy.\\n\\nResearch shows that the cancer-fighting benefits of phytoestrogen may be limited in certain people because of their genes. If your body naturally maintains lower levels of phytoestrogens, you may want to increase your intake of foods rich in phytoestrogen, such as vegetables, fruits, legumes, and soy.\",\n \"caption\": \"Healthy plant compound that fights cancer\",\n \"refreances\": [\n \"1. Holt, S. K., Kwon, E. M., Fu, R., Kolb, S., Feng, Z., Ostrander, E. A., & Stanford, J. L. (2012). Association of variants in estrogen-related pathway genes with prostate cancer risk. The Prostate, 73(1), 1–10. https://doi.org/10.1002/pros.22534\",\n \"2. Cotterchio, M., Boucher, B. A., Manno, M., Gallinger, S., Okey, A., & Harper, P. (2006). Dietary Phytoestrogen Intake Is Associated with Reduced Colorectal Cancer Risk. The Journal of Nutrition, 136(12), 3046–3053. https://doi.org/10.1093/jn/136.12.3046\",\n \"3. Yeager, M., Orr, N., Hayes, R. B., Jacobs, K. B., Kraft, P., Wacholder, S., Minichiello, M. J., Fearnhead, P., Yu, K., Chatterjee, N., Wang, Z., Welch, R., Staats, B. J., Calle, E. E., Feigelson, H. S., Thun, M. J., Rodriguez, C., Albanes, D., Virtamo, J., … Thomas, G. (2007). Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nature Genetics, 39(5), 645–649. https://doi.org/10.1038/ng2022\"\n ],\n \"GENES\": {\n \"CYP1B1\": {\n \"rs1056836\": {\n \"genotype\": \"GC\",\n \"effect_allels\": 1\n }\n },\n \"CASC8\": {\n \"rs1447295\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Sugar Preference\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your genetic test is correlated with an decreased preference to consume sweet foods.\",\n \"risk_management\": \"Avoiding excess sugar may be easier for you than others, but it's important to be vigilant about what you put in your body. Even seemingly healthy foods, such as protein bars, can have excess amounts of sugar. Avoid sugary drinks like soda and energy boosters. Eating sweet fruits daily, like apples, bananas, pomegranates, and mangos, are healthier substitutes if you are tempted to eat sugary food.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Sugar is a potentially dangerous component of the typical modern diet.\\n\\nWhile moderate amounts of natural sugar are perfectly fine, processed and refined sugar can lead to excess weight gain, diabetes, heart disease, and even cancer. It is added to almost all foods found the store.\\n\\nEveryone should minimize their intake of processed sugars, but the gene we examine here will tell us how much you prefer sugar on the genetic level.\",\n \"about\": \"Eating sugar releases \\\"feel good\\\" hormones in your brain, but unfortunately, it can cause serious harm to your body. Sugar increases your blood sugar levels, raising your risk for diabetes, making you gain more body fat, and possibly leading to disease, including cancer. \\n\\nThis genetic analysis determines how likely you are to seek out sugar, although anyone can become addicted to sugar.\\n\\nYour genetic desire for sugar is not a permanent curse: you can become used to eating less sugary foods over time. More importantly, you should read the labels of the food you buy in the store, as they often contain added sugars, even in foods you wouldn't expect to find sugar, such as pasta sauce, canned beans, and even frozen vegetables.\",\n \"caption\": \"Are you a sweet tooth or not?\",\n \"refreances\": [\n \"1. Eny, K. M., Wolever, T. M. S., Fontaine-Bisson, B., & El-Sohemy, A. (2008). Genetic variant in the glucose transporter type 2 is associated with higher intakes of sugars in two distinct populations. Physiological Genomics, 33(3), 355–360. https://doi.org/10.1152/physiolgenomics.00148.2007\",\n \"2. Michau, A., Guillemain, G., Grosfeld, A., Vuillaumier-Barrot, S., Grand, T., Keck, M., L’Hoste, S., Chateau, D., Serradas, P., Teulon, J., De Lonlay, P., Scharfmann, R., Brot-Laroche, E., Leturque, A., & Le Gall, M. (2013). Mutations inSLC2A2Gene Reveal hGLUT2 Function in Pancreatic β Cell Development. Journal of Biological Chemistry, 288(43), 31080–31092. https://doi.org/10.1074/jbc.m113.469189\",\n \"3. Zhou, K., Yee, S. W., Seiser, E. L., van Leeuwen, N., Tavendale, R., Bennett, A. J., Groves, C. J., Coleman, R. L., van der Heijden, A. A., Beulens, J. W., de Keyser, C. E., Zaharenko, L., Rotroff, D. M., Out, M., Jablonski, K. A., Chen, L., Javorský, M., Židzik, J., Levin, A. M., … Pearson, E. R. (2016). Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin. Nature Genetics, 48(9), 1055–1059. https://doi.org/10.1038/ng.3632\"\n ],\n \"GENES\": {\n \" GLUT2 or SLC2a2\": {\n \"rs5400\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Snacking behavior or Eating between meals\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Intermediate\",\n \"result_description\": \"Your genetic test result is correlated with an intermediate or typical likelihood of eating between meals.\",\n \"risk_management\": \"Avoiding excess food may be easier for you, but even if you only eat three times a day, it's important to be aware of what's actually in your food. Seemingly healthy meals can be loaded with added sugar, so be sure to check the label or nutrition facts. Avoid foods that are high in saturated fats or trans fats, as well as sugary foods and simple sugars. Here are healthier snacks you can have to curb cravings: mixed fruits, granola cereals, and nuts.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Eating in between meals can be problematic, especially for people trying to lose weight.\\n\\nBut it's especially challenging for certain people. Depending on your genetics, you may have more difficulty managing your diet, but being aware of the problem can give you the tools and motivation to work around it.\",\n \"about\": \"Eating can be a source of comfort, the result of a daily habit, or simply a response to stress. But some people are more likely to eat between meals because of their genes.\\n\\nEating in between meals is not necessarily bad: if you're sneaking in an extra salad with a light dressing, you're probably fine. But if you find yourself reaching for sugary snacks, it may cause long-term health problems. \\n\\nPrepare ahead of time by stocking your home with healthy snacks, and keep healthy alternatives at work to avoid running to fast food or gas station snacks at the last minute.\",\n \"caption\": \"An important weight management trait.\",\n \"refreances\": [\n \"1. Stutzmann, F., Cauchi, S., Durand, E., Calvacanti-Proença, C., Pigeyre, M., Hartikainen, A.-L., Sovio, U., Tichet, J., Marre, M., Weill, J., Balkau, B., Potoczna, N., Laitinen, J., Elliott, P., Järvelin, M.-R., Horber, F., Meyre, D., & Froguel, P. (2009). Common genetic variation near MC4R is associated with eating behaviour patterns in European populations. International Journal of Obesity, 33(3), 373–378. https://doi.org/10.1038/ijo.2008.279\",\n \"2. Loos, R. J. F., Lindgren, C. M., Li, S., Wheeler, E., Zhao, J. H., Prokopenko, I., Inouye, M., Freathy, R. M., Attwood, A. P., Beckmann, J. S., Berndt, S. I., Bergmann, S., Bennett, A. J., Bingham, S. A., Bochud, M., Brown, M., Cauchi, S., Connell, J. M., Cooper, C., … Barroso, I. (2008). Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nature Genetics, 40(6), 768–775. https://doi.org/10.1038/ng.140\"\n ],\n \"GENES\": {\n \"MC4R\": {\n \"rs17782313\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Hunger\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your result is correlated with less susceptibility to hunger. Your digestive psychosocial behavior tends to take longer period of time to feel hunger.\",\n \"risk_management\": \"It may still be difficult for you to ignore hunger, but your an advantage in this area since it take you longer period to feel hungry after meals compared to other people, which may help you while dieting or \\\"cutting.\\\"\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Your weight is the result of many things, including your daily habits, cultural influences, and genetics. Most importantly, your personal choices have the biggest impact. \\n\\nIf you have a genetic predisposition to excessive eating, don't worry: once you know the problem, it's easier to find a solution! Drinking extra water, finding new, low-calorie ways to flavor your foods, and being mindful of your eating habits can help.\",\n \"about\": \"Hunger can be caused by hormones, nutrients, exercise levels, and of course, an empty stomach. Knowing whether or not you're hungry for the right reasons can help you make better choices. Dehydration is often mistaken for hunger, so if you're hungry when you shouldn't be, consider having a large glass of water first.\\n\\nHunger is essentially about how intensely you feel the need to eat food.\",\n \"caption\": \"Don't let hunger derail you from achieving your goals.\",\n \"refreances\": [\n \"1. den Hoed, M., Westerterp-Plantenga, M. S., Bouwman, F. G., Mariman, E. C. M., & Westerterp, K. R. (2009). Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO. The American Journal of Clinical Nutrition, 90(5), 1426–1432. https://doi.org/10.3945/ajcn.2009.28053\"\n ],\n \"GENES\": {\n \"FTO\": {\n \"rs9939609\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Satiety\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your result is correlated with an faster response to food mouth and gut fill, resulting in faster satiety and feeling full.\",\n \"risk_management\": \"People with your genes typically feel full faster even with a small amount of food, which helps to prevent excessive eating. If you're trying to gain weight, you may need to focus on more calorie-dense foods in order to reach your goals. Although this is a good thing for planning diet, a well balanced diet should be maintained to avoid health problems.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Your personal choices have the biggest impact on your weight, but understanding your genetics can help you make smarter choices every day.\",\n \"about\": \"Your body recognizes that it's full because of both hormones and the physical fullness of your stomach. Eating more slowly and drinking more water can help trigger the appropriate feeling of satiety (fullness) before too many calories are consumed.\\n\\nSatiety is a measure of how \\\"full\\\" you feel after eating. \",\n \"caption\": \"Trouble feeling full? Here's why.\",\n \"refreances\": [\n \"1. den Hoed, M., Westerterp-Plantenga, M. S., Bouwman, F. G., Mariman, E. C. M., & Westerterp, K. R. (2009). Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO. The American Journal of Clinical Nutrition, 90(5), 1426–1432. https://doi.org/10.3945/ajcn.2009.28053\"\n ],\n \"GENES\": {\n \"FTO\": {\n \"rs9939609\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Appetite\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your result is correlated with low appetite or desire to eat food.\",\n \"risk_management\": \"Your genetics suggest that you have a lower risk of excess appetite. Increased appetite may cause overeating, which may lead to being overweight or obese. Adding more protein to your diet can increase feelings of fullness, helping you eat less at your next meal. Consuming a fiber-rich diet and drinking a glass of water before meals can decrease appetite and help you eat fewer calories. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"While it may not seem helpful to know about your genetic appetite levels, this trait may help you reason your way out of a snack or excessive eating: knowing that your desire for food is not based on your physical need for it can help reduce that desire.\",\n \"about\": \"Appetite is the desire for food, rather than the physical need for it. Simply smelling or seeing food can create an appetite, so don't let yourself be tricked into eating more than you need!\\n\\nAppetite determines how much you naturally want to eat. \",\n \"caption\": \"Bon appétit! \",\n \"refreances\": [\n \"1. Magno, F., Guaraná, H., Fonseca, A. C., Cabello, G., Carneiro, J., Pedrosa, A., Ximenes, A., & Rosado, E. (2018). Influence of FTO rs9939609 polymorphism on appetite, ghrelin, leptin, IL6, TNFα levels, and food intake of women with morbid obesity. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Volume 11, 199–207. https://doi.org/10.2147/dmso.s154978\",\n \"2. Dougkas, A., Yaqoob, P., Givens, D. I., Reynolds, C. K., & Minihane, A. M. (2013). The impact of obesity-related SNP on appetite and energy intake. British Journal of Nutrition, 110(6), 1151–1156. https://doi.org/10.1017/s0007114513000147\",\n \"3. Stutzmann, F., Cauchi, S., Durand, E., Calvacanti-Proença, C., Pigeyre, M., Hartikainen, A.-L., Sovio, U., Tichet, J., Marre, M., Weill, J., Balkau, B., Potoczna, N., Laitinen, J., Elliott, P., Järvelin, M.-R., Horber, F., Meyre, D., & Froguel, P. (2009). Common genetic variation near MC4R is associated with eating behaviour patterns in European populations. International Journal of Obesity, 33(3), 373–378. https://doi.org/10.1038/ijo.2008.279\",\n \"4. Imaizumi, T., Ando, M., Nakatochi, M., Yasuda, Y., Honda, H., Kuwatsuka, Y., Kato, S., Kondo, T., Iwata, M., Nakashima, T., Yasui, H., Takamatsu, H., Okajima, H., Yoshida, Y., & Maruyama, S. (2018). Effect of dietary energy and polymorphisms in BRAP and GHRL on obesity and metabolic traits. Obesity Research & Clinical Practice, 12(1), 39–48. https://doi.org/10.1016/j.orcp.2016.05.004\",\n \"5. Friedlander, Y., Li, G., Fornage, M., Williams, O. D., Lewis, C. E., Schreiner, P., Pletcher, M. J., Enquobahrie, D., Williams, M., & Siscovick, D. S. (2010). Candidate Molecular Pathway Genes Related to Appetite Regulatory Neural Network, Adipocyte Homeostasis and Obesity: Results from the CARDIA Study. Annals of Human Genetics, 74(5), 387–398. https://doi.org/10.1111/j.1469-1809.2010.00596.x\",\n \"6. Cole, S. A., Butte, N. F., Voruganti, V. S., Cai, G., Haack, K., Kent, J. W., Blangero, J., Comuzzie, A. G., McPherson, J. D., & Gibbs, R. A. (2009). Evidence that multiple genetic variants of MC4R play a functional role in the regulation of energy expenditure and appetite in Hispanic children. The American Journal of Clinical Nutrition, 91(1), 191–199. https://doi.org/10.3945/ajcn.2009.28514\"\n ],\n \"GENES\": {\n \"FTO\": {\n \"rs9939609\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"MC4R\": {\n \"rs17782313\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"GHRL or GHRLOS\": {\n \"rs696217\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LEP\": {\n \"rs17151919\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Sensitivity to bitter food\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"High\",\n \"result_description\": \"Based on the results of your genetic test, you may have a high sensitivity to bitter food. \",\n \"risk_management\": \"Prepare foods with a variety of colors and textures to minimize the presence of bitter tastes from healthy vegetables.\\nUse aromatic herbs and hot spices to add more flavor; however, you should avoid adding more sugar or salt to foods.\\nIf your diet permits, add small amounts of cheese, bacon bits, butter, olive oil, or toasted nuts to vegetables.\\nConsider trying combination dishes, such as casseroles, that can hide individual flavors and dilute taste.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Although not many studies can prove the link between PROP, or bitter taste sensitivity, and the likelihood of preferring bitter-tasting food, this table shows your genetic likelihood of being sensitive to bitterness.\",\n \"about\": \"Sensitivity to bitter taste can be physiologically measured using the PROP taste test. The substance 6-n-propylthiouracil (PROP) tastes bitter to some people but is tasteless to others. An individual's PROP taster status is physiologically determined. \\n\\nIn the existing body of scientific literature, there is some disagreement concerning sex differences in PROP taster status. Some studies have reported that females are more sensitive to PROP, while others did not find this effect. Several studies have shown that PROP sensitivity, as a measure of taste responsiveness, is linked to food acceptance, eating behavior, food preferences, and even certain personality characteristics.\",\n \"caption\": \"Bitter flavors and your food preferences.\",\n \"refreances\": [\n \"1. Genick, U. K., Kutalik, Z., Ledda, M., Souza Destito, M. C., Souza, M. M., A. Cirillo, C., Godinot, N., Martin, N., Morya, E., Sameshima, K., Bergmann, S., & le Coutre, J. (2011). Sensitivity of Genome-Wide-Association Signals to Phenotyping Strategy: The PROP-TAS2R38 Taste Association as a Benchmark. PLoS ONE, 6(11), e27745. https://doi.org/10.1371/journal.pone.0027745\",\n \"2. Mikołajczyk-Stecyna, J., Malinowska, A. M., & Chmurzynska, A. (2017). TAS2R38 and CA6 genetic polymorphisms, frequency of bitter food intake, and blood biomarkers among elderly woman. Appetite, 116, 57–64. https://doi.org/10.1016/j.appet.2017.04.029\",\n \"3. Ledda, M., Kutalik, Z., Souza Destito, M. C., Souza, M. M., Cirillo, C. A., Zamboni, A., Martin, N., Morya, E., Sameshima, K., Beckmann, J. S., le Coutre, J., Bergmann, S., & Genick, U. K. (2013). GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics. Human Molecular Genetics, 23(1), 259–267. https://doi.org/10.1093/hmg/ddt404\",\n \"4. Hayes, J. E., Feeney, E. L., Nolden, A. A., & McGeary, J. E. (2015). Quinine Bitterness and Grapefruit Liking Associate with Allelic Variants in TAS2R31. Chemical Senses, 40(6), 437–443. https://doi.org/10.1093/chemse/bjv027\"\n ],\n \"GENES\": {\n \"TAS2R38\": {\n \"rs10246939\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"PRH1-TAS2R14\": {\n \"rs1031391\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"TAS2R46\": {\n \"rs2708377\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"TAS2R19\": {\n \"rs10772420\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"TAS2R31 or PRH1-PRR4\": {\n \"rs10772420\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Preference to fatty food\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your genetic test is correlated with a decreased propensity to consume fatty foods.\",\n \"risk_management\": \"Your genes show that you have a low likelihood to prefer fatty food. Low-fat consumption may be good for people with heart-related conditions, but for healthy bodily function, you need to consume fat from food in moderation. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"The foods you love to eat are heavily determined by your genetics. Your genes can make you seek out fats in higher amounts, which can have potentially negative effects on body weight, health, and heart disease risk. \\n\\nThe genes we've analyzed here determines how intensely you can taste fats. If you can't taste fats very well, you're likely to eat more fats in order to compensate.\",\n \"about\": \"There are many factors that can affect how you perceive fatty food. There are certain genes that may cause some people to taste fat less acutely, causing them to seek out more fats in their diet. The less you can taste the fat, the more of it you will need to eat in order to enjoy the flavor. \\n\\nSince fatty foods can become problematic for weight management and health, it's important to make sure more of your fats come from healthy plant sources, which do not have cholesterol. \",\n \"caption\": \"Cravings for fatty foods? Learn more and stay healthy.\",\n \"refreances\": [\n \"1. Willer, C. J., Speliotes, E. K., Loos, R. J. F., Li, S., Lindgren, C. M., Heid, I. M., Berndt, S. I., Elliott, A. L., Jackson, A. U., Lamina, C., Lettre, G., Lim, N., Lyon, H. N., McCarroll, S. A., Papadakis, K., Qi, L., Randall, J. C., Roccasecca, R. M., Sanna, S., ... Hirschhorn, J. N. (2008). Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genetics, 41(1), 25–34. https://doi.org/10.1038/ng.287\",\n \"2. Li, P., Tiwari, H. K., Lin, W.-Y., Allison, D. B., Chung, W. K., Leibel, R. L., Yi, N., & Liu, N. (2013). Genetic association analysis of 30 genes related to obesity in a European American population. International Journal of Obesity, 38(5), 724–729. https://doi.org/10.1038/ijo.2013.140\",\n \"3. Park, S., Daily, J. W., Zhang, X., Jin, H. S., Lee, H. J., & Lee, Y. H. (2016). Interactions with the MC4R rs17782313 variant, mental stress and energy intake and the risk of obesity in Genome Epidemiology Study. Nutrition & Metabolism, 13, 38. https://doi.org/10.1186/s12986-016-0096-8\",\n \"4. AlSaleh, A., Frost, G. S., Griffin, B. A., Lovegrove, J. A., Jebb, S. A., Sanders, T. A. B., & O’Dell, S. D. (2011). PPARγ2 Gene Pro12Ala and PPARα Gene Leu162Val Single Nucleotide Polymorphisms Interact with Dietary Intake of Fat in Determination of Plasma Lipid Concentrations. Journal of Nutrigenetics and Nutrigenomics, 4(6), 354–366. https://doi.org/10.1159/000336362\",\n \"5. Fisher, E., Schreiber, S., Joost, H., Boeing, H., & Döring, F. (2011). A Two-Step Association Study Identifies CAV2 rs2270188 Single Nucleotide Polymorphism Interaction with Fat Intake in Type 2 Diabetes Risk. The Journal of Nutrition, 141(2), 177–181. https://doi.org/10.3945/jn.110.124206\",\n \"6. Bouchard-Mercier, A., Godin, G., Lamarche, B., Pérusse, L., & Vohl, M.-C. (2011). Effects of Peroxisome Proliferator-Activated Receptors, Dietary Fat Intakes and Gene–Diet Interactions on Peak Particle Diameters of Low-Density Lipoproteins. Journal of Nutrigenetics and Nutrigenomics, 4(1), 36–48. https://doi.org/10.1159/000324531\",\n \"7. Pioltine, M. B., de Melo, M. E., Santos, A., Machado, A. D., Fernandes, A. E., Fujiwara, C. T., Cercato, C., & Mancini, M. C. (2016). Genetic Variation in CD36 Is Associated with Decreased Fat and Sugar Intake in Obese Children and Adolescents. Journal of Nutrigenetics and Nutrigenomics, 9(5–6), 300–305. https://doi.org/10.1159/000455915\"\n ],\n \"GENES\": {\n \"FTO\": {\n \"rs9939609\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"AGRP\": {\n \"rs5030980\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"MC4R\": {\n \"rs17782313\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"PPARG\": {\n \"rs1801282\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"CAV2\": {\n \"rs926197\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n },\n \"PPARA\": {\n \"rs1800206\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"CD36\": {\n \"rs4545029\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Vegetable consumption\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Intermediate\",\n \"result_description\": \"According to your genetic test, you are likely to have a typical consumption of vegetables.\",\n \"risk_management\": \"Even though you don't have an issue with vegetable intake, it is best to eat a well-balanced diet following the Healthy Eating Plate which involves almost half of your plate being vegetables. Aim for color and variety, and please bear in mind that potatoes and french fries don't count because of their negative effect on blood sugar and blood pressure. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Knowing the genetic basis of your vegetable intake may help you understand your food preference and eating habits, which will determine your choice for a healthier diet and lifestyle.\",\n \"about\": \"Vegetable and fruit consumption is inversely related to the risk of cancer in a number of case-control studies, as well as in some large cohort studies.\\n\\nBased on the available evidence, the World Cancer Research Fund (WCRF) judged that vegetable consumption probably reduces the risk of cancers in the oral cavity and pharynx, larynx, esophagus, and stomach; meanwhile, evidence is limited on the role of vegetables on colon-rectum, endometrium, ovary, lungs, and nasopharynx.\",\n \"caption\": \"Veggies are critical in every good diet.\",\n \"refreances\": [\n \"1. Eriksson, N., Wu, S., Do, C. B., Kiefer, A. K., Tung, J. Y., Mountain, J. L., Hinds, D. A., & Francke, U. (2012). A genetic variant near olfactory receptor genes influences cilantro preference. Flavour, 1(22). https://doi.org/10.1186/2044-7248-1-22\",\n \"2. Sandell, M., Hoppu, U., Mikkilä, V., Mononen, N., Kähönen, M., Männistö, S., Rönnemaa, T., Viikari, J., Lehtimäki, T., & Raitakari, O. T. (2014). Genetic variation in the hTAS2R38 taste receptor and food consumption among Finnish adults. Genes & Nutrition, 9(6), 433. https://doi.org/10.1007/s12263-014-0433-3\",\n \"3. Mikołajczyk-Stecyna, J., Malinowska, A. M., & Chmurzynska, A. (2017b). TAS2R38 and CA6 genetic polymorphisms, frequency of bitter food intake, and blood biomarkers among elderly woman. Appetite, 116, 57–64. https://doi.org/10.1016/j.appet.2017.04.029\"\n ],\n \"GENES\": {\n \"TAS2R38\": {\n \"rs713598\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"CA6\": {\n \"rs2274333\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Tendency to binge eat\": {\n \"result_options\": [\n \"Low\",\n \"Intermediate\",\n \"High\"\n ],\n \"result\": \"Low\",\n \"result_description\": \"Your genes show that you have a lower tendency to binge eat compared to others. Binge eating may lead to a higher risk of being overweight or obese. \",\n \"risk_management\": \"According to studies, binge eating is stimulated by excessive stress, leading to sleep and food deprivation. Depriving yourself of food or specific food groups may eventually result in increased cravings and overeating due to lower levels of the hormone ghrelin and fasting blood sugar. Sticking to a regular eating pattern will help you prevent binge eating. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Binge eaters are no more or less “out of control” than anorexics, bulimics, or those struggling with other addictions. That's why it's important to know your genetic predisposition to binge eating in order to get the right prevention management or treatment from health care professionals.\",\n \"about\": \"Everyone overeats from time to time. Binge eating is different, though. You might suffer from binge eating if you regularly eat a lot of food in just a few hours -- even when you're not hungry -- to drown out emotions. Shame and guilt often follow bouts of binge eating.\\n\\nExamples of binge eating are:\\n\\nSneaking a large bag of candy into your room and finishing it in secret\\nEating a whole cake in one sitting, and then feeling guilty\\nFinishing three burgers, even when you're already uncomfortably full \\nEating to the point of pain\",\n \"caption\": \"Stay in control of your diet and meal plans.\",\n \"refreances\": [\n \"1. Monteleone, P., Tortorella, A., Castaldo, E., Di Filippo, C., & Maj, M. (2007). The Leu72Met polymorphism of the ghrelin gene is significantly associated with binge eating disorder. Psychiatric Genetics, 17(1), 13–16. https://doi.org/10.1097/ypg.0b013e328010e2c3\",\n \"2. Hinney, A., Hoch, A., Geller, F., Schäfer, H., Siegfried, W., Goldschmidt, H., Remschmidt, H., & Hebebrand, J. (2002). Ghrelin Gene: Identification of Missense Variants and a Frameshift Mutation in Extremely Obese Children and Adolescents and Healthy Normal Weight Students. The Journal of Clinical Endocrinology & Metabolism, 87(6), 2716. https://doi.org/10.1210/jcem.87.6.8672\",\n \"3. Boraska, V., Davis, O. S. P., Cherkas, L. F., Helder, S. G., Harris, J., Krug, I., Pei-Chi Liao, T., Treasure, J., Ntalla, I., Karhunen, L., Keski-Rahkonen, A., Christakopoulou, D., Raevuori, A., Shin, S.-Y., Dedoussis, G. V., Kaprio, J., Soranzo, N., Spector, T. D., Collier, D. A., & Zeggini, E. (2012). Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 159B(7), 803–811. https://doi.org/10.1002/ajmg.b.32087\",\n \"4. Monteleone, P., Zanardini, R., Tortorella, A., Gennarelli, M., Castaldo, E., Canestrelli, B., & Maj, M. (2006). The 196G/A (val66met) polymorphism of the BDNF gene is significantly associated with binge eating behavior in women with bulimia nervosa or binge eating disorder. Neuroscience Letters, 406(1–2), 133–137. https://doi.org/10.1016/j.neulet.2006.07.040\",\n \"5. Cellini, E., Castellini, G., Ricca, V., Bagnoli, S., Tedde, A., Rotella, C. M., Faravelli, C., Sorbi, S., & Nacmias, B. (2010). Glucocorticoid receptor gene polymorphisms in Italian patients with eating disorders and obesity. Psychiatric Genetics, 20(6), 282–288. https://doi.org/10.1097/ypg.0b013e32833a2142\",\n \"6. Castellini, G., Franzago, M., Bagnoli, S., Lelli, L., Balsamo, M., Mancini, M., Nacmias, B., Ricca, V., Sorbi, S., Antonucci, I., Stuppia, L., & Stanghellini, G. (2017). Fat mass and obesity-associated gene (FTO) is associated to eating disorders susceptibility and moderates the expression of psychopathological traits. PLOS ONE, 12(3), e0173560. https://doi.org/10.1371/journal.pone.0173560\",\n \"7. Davis, C., Patte, K., Zai, C., & Kennedy, J. L. (2017). Polymorphisms of the oxytocin receptor gene and overeating: the intermediary role of endophenotypic risk factors. Nutrition & Diabetes, 7(5), e279. https://doi.org/10.1038/nutd.2017.24\",\n \"8. Micali, N., Crous-Bou, M., Treasure, J., & Lawson, E. A. (2016). Association Between Oxytocin Receptor Genotype, Maternal Care, and Eating Disorder Behaviours in a Community Sample of Women. European Eating Disorders Review, 25(1), 19–25. https://doi.org/10.1002/erv.2486\"\n ],\n \"GENES\": {\n \"GHRL\": {\n \"rs696217\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"GHRL@DUB266\": {\n \"rs34911341\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"BDNF\": {\n \"rs6265\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"NR3C1\": {\n \"rs6198\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"FTO\": {\n \"rs9939609\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"OXTR@DUB867\": {\n \"rs53576\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"OXTR@DUB105\": {\n \"rs2268491\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n }\n }\n }\n }\n}"}],"_postman_id":"86d56a9d-612c-4fcc-9ab6-4284f072a2fb"},{"name":"Fitness Report","id":"18b8a91e-1a84-4f3f-9282-de18fbd01737","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/fitness/report","description":"

Description: This Endpoint generates/retrieves the latest Fitness report for any customer

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Your Total Weight Loss from Exercise

\\n\\nWhile exercise can help lower body fat, it may also cause a lower total weight, including losses in muscle, tissue, water, and more.\\n\\nThe FTO gene is linked to an overall change in body weight, not just body fat. Maintaining a healthy level of muscle is important for increasing your body's ability to burn calories. \",\n \"about\": \"

Weight Loss (the Good and Bad)

\\n\\nNot all weight loss is good. Sometimes, diets can push your body to the extreme, causing muscle to deteriorate. Since muscles are important to your overall health (and help you burn more calories during the day), you want to maximize fat loss while minimizing muscle loss (or increasing muscle mass).\\n\\nThis genetic analysis determines your weight loss potential, regardless of whether it's muscle or fat. People who lose too much muscle in response to dieting should be careful to slowly lose weight and maintain a resistance training routine that preserves healthy muscle mass. \",\n \"caption\": \"Weight Loss Potential During Exercise\",\n \"refreances\": [\n \"1.\\tGarenc, C., Pérusse, L., Bergeron, J., Gagnon, J., Chagnon, Y. C., Borecki, I. B., Leon, A. S., Skinner, J. S., Wilmore, J. H., Rao, D. C., & Bouchard, C. (2001). Evidence of LPL gene-exercise interaction for body fat and LPL activity: the HERITAGE Family Study. Journal of Applied Physiology, 91(3), 1334–1340. https://doi.org/10.1152/jappl.2001.91.3.1334 \",\n \"2.\\tMitchell, J. A., Church, T. S., Rankinen, T., Earnest, C. P., Sui, X., & Blair, S. N. (2009). FTO Genotype and the Weight Loss Benefits of Moderate Intensity Exercise. Obesity, 18(3), 641–643. https://doi.org/10.1038/oby.2009.311 \",\n \"3.\\tOrkunoglu-Suer, F. E., Gordish-Dressman, H., Clarkson, P. M., Thompson, P. D., Angelopoulos, T. J., Gordon, P. M., Moyna, N. M., Pescatello, L. S., Visich, P. S., Zoeller, R. F., Harmon, B., Seip, R. L., Hoffman, E. P., & Devaney, J. M. (2008). INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men. BMC Medical Genetics, 9(117), 1–8. https://doi.org/10.1186/1471-2350-9-117 \",\n \"4.\\tRankinen, T., Rice, T., Teran-Garcia, M., Rao, D. C., & Bouchard, C. (2009). FTO Genotype Is Associated With Exercise Training–induced Changes in Body Composition. Obesity, 18(2), 322–326. https://doi.org/10.1038/oby.2009.205 \",\n \"5.\\tSzendrei, B., González-Lamuño, D., Amigo, T., Wang, G., Pitsiladis, Y., Benito, P. J., Gomez-Candela, C., Calderón, F. J., & Cupeiro, R. (2016). Influence of ADRB2 Gln27Glu and ADRB3 Trp64Arg polymorphisms on body weight and body composition changes after a controlled weight-loss intervention. Applied Physiology, Nutrition, and Metabolism, 41(3), 307–314. https://doi.org/10.1139/apnm-2015-0425\"\n ],\n \"GENES\": {\n \"FTO\": {\n \"rs8050136\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"INSIG2\": {\n \"rs17047697\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"ADRB3\": {\n \"rs4994\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"LPL\": {\n \"rs328\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Power vs Endurance\": {\n \"result_options\": [\n \"Endurance Bias\",\n \"Balanced\",\n \"Power Bias\"\n ],\n \"result\": \"Balanced\",\n \"result_description\": \"Your genetic potential on training intensity is a balance of endurance and power genetics. Generally, your muscular anatomy is correlated with genes that are both present in power-type and endurance-type athletes at the elite level.\",\n \"risk_management\": \"You're likely to perform well in both endurance and power sports. A combination of both exercise types will help you get the most out of your body and health journey.\\n\\nIn resistance strength training, you may be able to balance high weight, low repetition with low weight, high-volume resistance training to experience hypertrophic progress (muscle growth) in a short time. For bodybuilding, you'll grow best depending on other factors like energy levels, inflammation, medical history, muscular disorders, motivation, and nutrition. Don't forget that progressive overload, or increasing loads as your body adapts, will give you increased muscle gains. It is advised to alternate cardio and resistance trainings. Both trainings can be done three times a week.\\n\\nGenerally, you're likely to have less starting VO2 max capacity (an aerobic measure of endurance); therefore, cardio exercises are recommended to ensure that your aerobic ability can keep up with your increased load training.\",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*You're perfectly balanced! A combination of both cardio and resistance strength exercises will help you get the most out of your body and health journey.\",\n \"*You should alternate cardio and resistance workouts. Both should be done three times a week.\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"In this report, we analyze the genes that impact how your body responds to different types of exercise. We've collected a set of genes that affect your muscular power, endurance, inflammation, and strength. In addition, we've looked at how your muscles grow in response to exercise.\",\n \"about\": \"This part of your genetic test will reveal how well your body responds to two different kinds of exercise.\\n\\nEndurance exercise, or “low-intensity” exercise, involves longer periods of exertion. Jogging, participating in a marathon, or resistance training with lighter weights and higher reps all work for this trait.\\n\\nPower, or “high-intensity,” refers to short bursts of exercise with more effort. Typically, this involves exercise as short as 10-30 seconds, with short breaks in between, like with High-Intensity Interval Training (HIIT).\\n\\nNo matter what your DNA reveals, this is not a test for what sports you would be good at or where you might be successful. \\n\\nInstead, you can use this guide to get the most out of your training while focusing on your own personal goals.\",\n \"caption\": \"Finding the Best Exercise for You: What Does Your Body Respond to the Best?\",\n \"refreances\": [\n \"1.Ahmetov, I. I., Khakimullina, A. M., Popov, D. V., Missina, S. S., Vinogradova, O. L., & Rogozkin, V. A. (2008). Polymorphism of the vascular endothelial growth factor gene (VEGF) and aerobic performance in athletes. Human Physiology, 34(4), 477–481. https://doi.org/10.1134/s0362119708040129 \",\n \"2.\\tBanting, L. K., Pushkarev, V. P., Cieszczyk, P., Zarebska, A., Maciejewska-Karlowska, A., Sawczuk, M., Leońska-Duniec, A., Dyatlov, D. A., Orekhov, E. F., Degtyarev, A. V., Pushkareva, Y. E., Yan, X., Birk, R., & Eynon, N. (2015). Elite athletes’ genetic predisposition for altered risk of complex metabolic traits. BMC Genomics, 16(1), 25. https://doi.org/10.1186/s12864-014-1199-0 \",\n \"3.\\tCosta-Urrutia, P., Abud, C., Franco-Trecu, V., Colistro, V., Rodríguez-Arellano, M. E., Granados, J., & Seelaender, M. (2018). Genetic susceptibility to pre diabetes mellitus and related association with obesity and physical fitness components in Mexican-Mestizos. Primary Care Diabetes, 12(5), 416–424. https://doi.org/10.1016/j.pcd.2018.07.005 \",\n \"4.\\tDöring, F., Onur, S., Fischer, A., Boulay, M. R., Pérusse, L., Rankinen, T., Rauramaa, R., Wolfarth, B., & Bouchard, C. (2010). A common haplotype and the Pro582Ser polymorphism of the hypoxia-inducible factor-1α (HIF1A) gene in elite endurance athletes. Journal of Applied Physiology, 108(6), 1497–1500. https://doi.org/10.1152/japplphysiol.01165.2009 \",\n \"5.\\tGayagay, G., Yu, B., Hambly, B., Boston, T., Hahn, A., Celermajer, D. S., & Trent, R. J. (1998). Elite endurance athletes and the ACE I allele - the role of genes in athletic performance. Human Genetics, 103(1), 48–50. https://doi.org/10.1007/s004390050781 \",\n \"6.\\tRoth, S. M., Walsh, S., Liu, D., Metter, E. J., Ferrucci, L., & Hurley, B. F. (2007). The ACTN3 R577X nonsense allele is under-represented in elite-level strength athletes. European Journal of Human Genetics, 16(3), 391–394. https://doi.org/10.1038/sj.ejhg.5201964 \",\n \"7.\\tRuiz, J. R., Buxens, A., Artieda, M., Arteta, D., Santiago, C., Rodríguez-Romo, G., Lao, J. I., Gómez-Gallego, F., & Lucia, A. (2010). The −174 G/C polymorphism of the IL6 gene is associated with elite power performance. Journal of Science and Medicine in Sport, 13(5), 549–553. https://doi.org/10.1016/j.jsams.2009.09.005 \",\n \"8.\\tTharabenjasin, P., Pabalan, N., & Jarjanazi, H. (2019). Association of the ACTN3 R577X (rs1815739) polymorphism with elite power sports: A meta-analysis. PLOS ONE, 14(5), e0217390. https://doi.org/10.1371/journal.pone.0217390 \",\n \"9.\\tWeyerstraß, J., Stewart, K., Wesselius, A., & Zeegers, M. (2018). Nine genetic polymorphisms associated with power athlete status – A Meta-Analysis. Journal of Science and Medicine in Sport, 21(2), 213–220. https://doi.org/10.1016/j.jsams.2017.06.012\",\n \"10. \\tWolfarth, B., Rankinen, T., Mühlbauer, S., Scherr, J., Boulay, M. R., Pérusse, L., Rauramaa, R., & Bouchard, C. (2007). Association between a β2-adrenergic receptor polymorphism and elite endurance performance. Metabolism, 56(12), 1649–1651. https://doi.org/10.1016/j.metabol.2007.07.006\"\n ],\n \"GENES\": {\n \"ACTN3\": {\n \"rs1815739\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"PPARA\": {\n \"rs4253778\": {\n \"genotype\": \"CG\",\n \"effect_allels\": 1\n }\n },\n \"IL6\": {\n \"rs1800795\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"AGT\": {\n \"rs699\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"HIF1A\": {\n \"rs11549465\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"PPARGC1A\": {\n \"rs8192678\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"ADRB2\": {\n \"rs1042713\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"ACE\": {\n \"rs4343\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"LPL\": {\n \"rs331\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"ACTN3@DUB552\": {\n \"rs1815739\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Post Exercise Recovery Rate\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE \",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your result is correlated with a slower post-exercise recovery rate; you should take more time to recover after an intense workout.\",\n \"risk_management\": \"Your body likely recovers slower than other people's after exercise. You should take 3 to 4 days of rest in between strenuous workouts. Lighter exercises, such as jogging or medium-intensity elliptical training, can be done more frequently to help you stay active.\\n\\nBe sure to adjust your workout program to your unique levels of rest, and listen to your body: soreness and fatigue are signs of excess exercise.\",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*Relax! Your body likely recovers slower than other people's after exercise, so plenty of rest, hydration, and a warm bath is important for you.\",\n \"*You should take 3 to 4 days of rest in between strenuous workouts. \"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Your body's inflammation and antioxidant levels can make exercise recovery slower. \\n\\nAntioxidants help protect your body from free radicals, which are formed during exercise and stress. \\n\\nWith lower levels of inflammation and more antioxidant protection, you may be able to exercise more frequently without excess soreness and fatigue.\\n\\nThese genes influence your body's inflammation and antioxidant levels.\",\n \"about\": \"Typically, you should rest for 48 hours after intense exercise. \\n\\nIf your genetic variations lead to slower recovery, simply take a longer rest in between workouts: about 3 to 4 days.\\n\\nYou can stay active with light to moderate exercises, such as walking and hiking, in between your more strenuous activities.\\n\\nAbove all, listen to your body. If you're feeling unusual pain, soreness, or exhaustion, give yourself a break. Preserving your health and body for the long-run is more important than hitting the gym every single day. This report can be used by your genetic health expert to decide the frequency of your workouts.\",\n \"caption\": \"See How Your Body Recovers After Exercise\",\n \"refreances\": [\n \"1.\\tBaumert, P., Lake, M. J., Stewart, C. E., Drust, B., & Erskine, R. M. (2016). Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing. European Journal of Applied Physiology, 116(9), 1595–1625. https://doi.org/10.1007/s00421-016-3411-1 \",\n \"2.\\tGallicchio, L., Chang, H., Christo, D. K., Thuita, L., Huang, H.-Y., Strickland, P., Ruczinski, I., Hoffman, S. C., & Helzlsouer, K. J. (2008). Single Nucleotide Polymorphisms in Inflammation-related Genes and Mortality in a Community-based Cohort in Washington County, Maryland. American Journal of Epidemiology, 167(7), 807–813. https://doi.org/10.1093/aje/kwm378 \",\n \"3.\\tPickering, C., Kiely, J., Suraci, B., Quigley, C., & Watson, J. (2017). A genetic-based algorithm for recovery: A pilot study. A Genetic-Based Algorithm for Recovery: A Pilot Study, 1–11. https://doi.org/10.1101/166181 \",\n \"4.\\tYamin, C., Duarte, J. A. R., Oliveira, J. M. F., Amir, O., Sagiv, M., Eynon, N., Sagiv, M., & Amir, R. E. (2008). IL6 (-174) and TNFA (-308) promoter polymorphisms are associated with systemic creatine kinase response to eccentric exercise. European Journal of Applied Physiology, 104(3), 579–586. https://doi.org/10.1007/s00421-008-0728-4\"\n ],\n \"GENES\": {\n \"SOD2\": {\n \"rs4880\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"IL6\": {\n \"rs1800795\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"CRP\": {\n \"rs1205\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"TNF\": {\n \"rs1800629\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Circadian rhythm\": {\n \"result_options\": [\n \"Low\",\n \"INTERMEDIATE\\t\",\n \"High\"\n ],\n \"result\": \"INTERMEDIATE\\t\",\n \"result_description\": \"Your genes are correlated with a intermediate likelihood of being a morning person; you are more likely to be awake and energized in the morning.\",\n \"risk_management\": \"We recommend scheduling your training sessions when your body is most active and brain is most alert. Exercising at the wrong time for your internal clock may lead to increased levels of exhaustion and a higher chance of giving up.\",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*Start the day off right! We recommend scheduling your training sessions anytime in the day but preferably between 9am to 3pm.\",\n \"*In order to maintain a good sleep schedule, avoid artificial light, such as the light from your phone or computer, too close to bedtime.\"\n ],\n \"star_rating\": 2,\n \"snp_table_caption\": \"The genes below tests a person's likelihood of being a morning person. Working with your natural circadian rhythm can help you achieve the best results and improve your chances of long-term success.\",\n \"about\": \"Circadian rhythms are natural and innate mechanisms that control the physiological activities of an organism, which can change on a daily, seasonal, or yearly basis.\\n\\nYour genetic analysis here can help you plan your workout more effectively. Exercising when you are tired can disrupt your sleep cycles, and \\\"morning people\\\" should refrain from working out late in the evening. \\n \",\n \"caption\": \"Planning Your Best Time for Exercise\",\n \"refreances\": [\n \"1. Hu, Y., Shmygelska, A., Tran, D., Eriksson, N., Tung, J. Y., & Hinds, D. A. (2016). GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person. Nature Communications, 7(10448), 1-. https://doi.org/10.1038/ncomms10448 \",\n \"2. Lane, J. M., Vlasac, I., Anderson, S. G., Kyle, S. D., Dixon, W. G., Bechtold, D. A., Gill, S., Little, M. A., Luik, A., Loudon, A., Emsley, R., Scheer, F. A. J. L., Lawlor, D. A., Redline, S., Ray, D. W., Rutter, M. K., & Saxena, R. (2016). Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank. Nature Communications, 7(1), 10889. https://doi.org/10.1038/ncomms10889 \",\n \"3. Parsons, M. J., Lester, K. J., Barclay, N. L., Archer, S. N., Nolan, P. M., Eley, T. C., & Gregory, A. M. (2014). Polymorphisms in the circadian expressed genesPER3andARNTL2are associated with diurnal preference andGNβ3with sleep measures. Journal of Sleep Research, 23(5), 595–604. https://doi.org/10.1111/jsr.12144\"\n ],\n \"GENES\": {\n \"VIP\": {\n \"rs9479402\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"PER2\": {\n \"rs55694368\": {\n \"genotype\": \"GT\",\n \"effect_allels\": 1\n }\n },\n \"HCRTR2 (aka OX2R)\": {\n \"rs35833281\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"RASD1\": {\n \"rs11545787\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"PER3 (VAMP3)\": {\n \"rs11121022\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n },\n \"FBXL3 (CLN5)\": {\n \"rs9565309\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"PER3\": {\n \"rs10462021\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"HDL Cholesterol and Exercise\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your result shows a moderate increase in HDL (good cholesterol) in response to exercise.\",\n \"risk_management\": \"Exercise and a good diet are both important parts of maintaining good cholesterol. For your unique body, at least 20-40 minutes of exercise per day will help optimize your HDL.\",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*It is recommended that you exercise three to four times a week (20 to 40 minutes a day) to increase your HDL levels.\",\n \"*Keep your protein consumption high -- as much as 25% of daily calories-- to optimize your diet. That should come to about 100 - 150g protein per day.\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"HDL is the good cholesterol that improves your heart health. Low levels of HDL are strongly associated with the likelihood of developing atherosclerotic coronary heart diseases (CHD). High HDL reduces your risk of heart attack and stroke. \\n\\nExercise can stimulate the body's ability to increase your HDL; however, only some individuals are responsive to it, depending on their DNA. \",\n \"about\": \"

Cholesterol and Exercise

\\n\\nHDL, or “good cholesterol,” affects your risk for heart disease. More HDL is generally healthier.\\n\\nSee how your body’s HDL responds to exercise below.\",\n \"caption\": \"How \\\"good cholesterol\\\" increases in response to exercise.\",\n \"refreances\": [\n \"1.\\tAhmad, T., Chasman, D. I., Buring, J. E., Lee, I.-M., Ridker, P. M., & Everett, B. M. (2011). Physical Activity Modifies the Effect of LPL, LIPC , and CETP Polymorphisms on HDL-C Levels and the Risk of Myocardial Infarction in Women of European Ancestry. Circulation: Cardiovascular Genetics, 4(1), 74–80. https://doi.org/10.1161/circgenetics.110.957290 \",\n \"2.\\tPetr, M., Stastny, P., Zajac, A., Tufano, J., & Maciejewska-Skrendo, A. (2018). The Role of Peroxisome Proliferator-Activated Receptors and Their Transcriptional Coactivators Gene Variations in Human Trainability: A Systematic Review. International Journal of Molecular Sciences, 19(5), 1472. https://doi.org/10.3390/ijms19051472\"\n ],\n \"GENES\": {\n \"PPARD\": {\n \"rs2016520\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"LIPC\": {\n \"rs1800588\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"CETP\": {\n \"rs1532624\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Blood Pressure and Exercise\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your result is correlated with a low risk for hypertension (high blood pressure). Also, focus on your diet and supplements as you have less anti-hypertensive benefits from exercise.\",\n \"risk_management\": \"People with low hypertension risk are still encouraged to exercise because of the overall wellness benefits it offers. \\n\\nWeightlifting and aerobic exercise have long-term beneficial effects, but consult your doctor first if you have high blood pressure. High blood pressure may not show any signs or symptoms, even if your blood pressure reaches dangerous levels.\\n\\nAs people age, hypertension risk increases; check your blood pressure every year if you are not yet diagnosed. If diagnosed, monitor it regularly and adhere to an optimized diet and training plan. A medical professional can obtain your blood pressure reading. Public blood pressure machines are available in most pharmacies, if you cannot get an appointment with your physician.\",\n \"actionable_trait\": \"Yes\",\n \"recommendations\": [\n \"*While your blood pressure may not go up dramatically, you should still exercise at least three times a week for at least 20 minutes. \",\n \"*If you do have a case of hypertension, a focus on diet that helps lower blood pressure can be more beneficial.\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"

The Impact of Exercise on Your Blood Pressure

\\n\\nThe EDN1 gene changes how well your blood pressure responds to exercise.\\n\\nFor some people, exercise may not have a significant impact on blood pressure, and a greater focus on diet may be necessary to improve your overall health. \",\n \"about\": \"

Lowering Blood Pressure Through Exercise.

\\n\\nDepending on your genes, exercise can lower your blood pressure significantly, or it may have very little effect.\\n\\nYour DNA analysis reveals the impact exercise has on your blood pressure compared to other people, but in general, all people will enjoy the heart health benefits of exercise, even if this effect is slightly reduced. \",\n \"caption\": \"Do you have a tendency for high blood pressure?\",\n \"refreances\": [\n \"1.\\tGoni, L., Cuervo, M., Milagro, F. I., & Martínez, J. A. (2016). Influence of fat intake and BMI on the association of rs1799983 NOS3 polymorphism with blood pressure levels in an Iberian population. European Journal of Nutrition, 56(4), 1589–1596. https://doi.org/10.1007/s00394-016-1203-3 \",\n \"2.\\tRankinen, T., Church, T., Rice, T., Markward, N., Leon, A. S., Rao, D. C., Skinner, J. S., Blair, S. N., & Bouchard, C. (2007). Effect of Endothelin 1 Genotype on Blood Pressure Is Dependent on Physical Activity or Fitness Levels. Hypertension, 50(6), 1120–1125. https://doi.org/10.1161/hypertensionaha.107.093609 \",\n \"3.\\tRauramaa, R., Kuhanen, R., Lakka, T. A., Väisänen, S. B., Halonen, P., Alén, M., Rankinen, T., & Bouchard, C. (2002). Physical exercise and blood pressure with reference to the angiotensinogen M235T polymorphism. Physiological Genomics, 10(2), 71–77. https://doi.org/10.1152/physiolgenomics.00050.2002 \",\n \"4.\\tTrapé, A. A., Lizzi, E. A. . d. a. . S., Gonçalves, T. C. P., Rodrigues, J. A. L., Tavares, S. S., Lacchini, R., Pinheiro, L. C., Ferreira, G. C., Tanus-Santos, J. E., Ovídio, P. P., Jordão, A. A., Jacomini, A. M., Zago, A. S., & Bueno Júnior, C. R. (2017). Effect of Multicomponent Training on Blood Pressure, Nitric Oxide, Redox Status, and Physical Fitness in Older Adult Women: Influence of Endothelial Nitric Oxide Synthase (NOS3) Haplotypes. Oxidative Medicine and Cellular Longevity, 2017, 1–12. https://doi.org/10.1155/2017/2578950\"\n ],\n \"GENES\": {\n \"AGTmet\": {\n \"rs699\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Inflammation & Pain Tolerance\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\\t\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your genetic result is correlated with low inflammation. \",\n \"risk_management\": \"Stress, nutritional deficiencies, dehydration, sprains and strains, sleep deficiency, and over-exertion can all affect your pain and inflammation. Your experiences and lifestyle also modify your pain tolerance.\\n\\nIf you experience any workout-related injuries to muscles, employ the RICE method - Rest, Ice (15-20 minutes, 3x a day), Compression (compression bandage to help reduce swelling), and Elevation (elevate the injured area to minimize inflammation). Other strategies include: OTC pain relievers, careful stretching of the affected muscle, regular participation in relaxation, and stress-lowering activities, such as yoga and meditation. Seek medical attention if your pain occurs along with difficulty breathing, trouble swallowing, dizziness, stiff neck and high fever, muscle weakness, an inability to move the affected area, vomiting, reduction in urine volume, or sudden water retention (bloating).\\n\\nPlasma concentrations of ROS and other free radicals are best measured via UV/vis (ultraviolet-visible) spectrophotometry in clinical laboratories. Pain and inflammation can also be verified through physical examination by medical practitioners. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"While pain tolerance is also affected by your life experiences, there is a strong genetic component as well. \\n\\nThe COMT gene has been associated with various levels of pain tolerance, depending on your unique genetic markers. \",\n \"about\": \"Pain is unpleasant, but being able to tolerate or ignore it has its benefits.\\n\\nWhen performing a tough workout, pain tolerance can allow you to push yourself to new limits. However, ignoring your pain can lead to injury, so be careful to monitor your body closely.\\n\\nHere’s a look at your genetic indicators of pain tolerance, as well as a few quick tips for improving your pain tolerance, no matter what your genetic profile reveals. \",\n \"caption\": \"Your Ability to Tolerate Pain\",\n \"refreances\": [\n \"1.\\tAndersen, S., & Skorpen, F. (2009). Variation in theCOMTgene: implications for pain perception and pain treatment. Pharmacogenomics, 10(4), 669–684. https://doi.org/10.2217/pgs.09.13 \",\n \"2.\\tBelfer, I., Segall, S. K., Lariviere, W. R., Smith, S. B., Dai, F., Slade, G. D., Rashid, N. U., Mogil, J. S., Campbell, C. M., Edwards, R. R., Liu, Q., Bair, E., Maixner, W., & Diatchenko, L. (2013). Pain modality- and sex-specific effects of COMT genetic functional variants. Pain, 154(8), 1368–1376. https://doi.org/10.1016/j.pain.2013.04.028 \",\n \"3.\\tGalicia, J. C., Tai, H., Komatsu, Y., Shimada, Y., Akazawa, K., & Yoshie, H. (2004). Polymorphisms in the IL-6 receptor (IL-6R) gene: strong evidence that serum levels of soluble IL-6R are genetically influenced. Genes & Immunity, 5(6), 513–516. https://doi.org/10.1038/sj.gene.6364120 \",\n \"4.\\tNielsen, L. M., Olesen, A. E., Sato, H., Christrup, L. L., & Drewes, A. M. (2016). Association between Gene Polymorphisms and Pain Sensitivity Assessed in a Multi-Modal Multi-Tissue Human Experimental Model - An Explorative Study. Basic & Clinical Pharmacology & Toxicology, 119(4), 360–366. https://doi.org/10.1111/bcpt.12601 \",\n \"5.\\tPickering, C., Kiely, J., Suraci, B., Quigley, C., & Watson, J. (2017). A genetic-based algorithm for recovery: A pilot study. BioRxiv Preprint, 1–11. https://doi.org/10.1101/166181\"\n ],\n \"GENES\": {\n \"IL6R\": {\n \"rs2228145\": {\n \"genotype\": \"CA\",\n \"effect_allels\": 1\n }\n },\n \"COMT\": {\n \"rs4680\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Exercise induced ischemia\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your result is correlated with low risk for exercise-induced ischemia\",\n \"risk_management\": \"Although you're less likely to experience exercise-induced myocardial ischemia, it is always recommended that you gradually work your way up to intense exercise to condition your heart effectively. Always warm up before a workout. Evidence shows that 1 to 3 episodes of exercise per week will provide strong cardio-protection. If you are inactive, begin with just one workout per week. Research suggests that 60 minutes of exercise, performed at about 75-80% maximum oxygen consumption, is best for heart health. In just 9 days of inactivity, heart health benefits will be lost, so regular exercise is critical to maintaining a healthy heart.\\n\\nWarming up by stretching allows your blood vessels, blood pressure, and blood supply to adapt to subsequent, intense physical activity. Exercise improves your risk of hypercholesterolemia (high cholesterol), hypertension (high blood pressure), diabetes, and cardiovascular diseases. An electrocardiogram (ECG) is one diagnostic test for ischemia, which is typically done in hospitals. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"

Calculating Your Ischemia Risk

\\n\\nExercise is generally healthy and recommended for virtually everyone at all fitness levels.\\n\\nHowever, it is possible for some people to experience a heart attack or stroke, especially during long, intense workouts, such as a marathon race. This risk is much higher without proper training.\\n\\nA certain variant in the CCL2 gene has been linked to an increased risk of ischemia as the result of exercise.\",\n \"about\": \"

Your Genetic Risk for Heart Attack or Stroke in Response to Exercise.

\\n\\nExercise reduces your risk of coronary artery disease, heart attack, and stroke. \\n\\nBut some people may be at risk of experiencing myocardial ischemia (blood-flow restriction that can lead to heart attack or stroke) during intense exercise. Some people with a risk for ischemia don't show any signs or symptoms (silent ischemia). \\n\\nRegular training and slow, steady progress can reduce your risks. Pushing yourself too hard in one session can put you in danger, no matter your genes, so it's best to increase the intensity and duration of your workouts slowly.\",\n \"caption\": \"Heart attack or stroke may occur as the result of certain exercises.\",\n \"refreances\": [\n \"1. Arakelyan, A., Zakharyan, R., Hambardzumyan, M., Petrkova, J., Olsson, M. C., Petrek, M., & Boyajyan, A. (2014). Functional Genetic Polymorphisms of Monocyte Chemoattractant Protein 1 and C-C Chemokine Receptor Type 2 in Ischemic Stroke. Journal of Interferon & Cytokine Research, 34(2), 100–105. https://doi.org/10.1089/jir.2013.0030 \",\n \"2. Cai, G., Zhang, B., Weng, W., Shi, G., & Huang, Z. (2014). The associations between the MCP-1 −2518 A/G polymorphism and ischemic heart disease and ischemic stroke: a meta-analysis of 28 research studies involving 21,524 individuals. Molecular Biology Reports, 42(5), 997–1012. https://doi.org/10.1007/s11033-014-3836-8 \",\n \"3. Palmer, C. N. A., Kimber, C. H., Doney, A. S. F., Proia, A. S., Morris, A. D., Gaetani, E., Quarta, M., Smith, R. C., & Pola, R. (2010). Combined Effect of Inflammatory Gene Polymorphisms and the Risk of Ischemic Stroke in a Prospective Cohort of Subjects With Type 2 Diabetes: A Go-DARTS Study. Diabetes, 59(11), 2945–2948. https://doi.org/10.2337/db09-1690\"\n ],\n \"GENES\": {\n \"CCL2/MCP-1\": {\n \"rs1024611\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Muscle Hypertrophy\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\\t\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\\t\",\n \"result_description\": \"Your result is correlated with a intermediate likelihood of muscular hypertrophy (growth).\",\n \"risk_management\": \"Two factors contribute to hypertrophy (growth): sarcoplasmic hypertrophy, which involves increased muscle glycogen stores, and myofibrillar hypertrophy, the growth of the fibers of your muscles. \\n\\nResearch has found that carbohydrate-protein supplements enhance and increase the rate of post-exercise muscle glycogen storage; hence, post-workout mass-gaining shakes which have carbohydrate-protein ingredients can be better than pure protein supplements to maximize hypertrophy. \\n\\nProtein synthesis increases in response to resistance training. High-volume resistance training and compound exercises can induce a significant overall hypertrophic response. However, do not overtrain, as your body needs rest to actively build muscle. Other factors that will help you optimize your training will be uncovered from insights in your genetic other traits, so be sure to examine your entire DNA report for the right strategies for you.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"

Your Muscle Hypertrophy

\\n\\nThe genes in this report change how effectively your muscles grow in response to exercise. \\n\\nUnique advantages in explosive strength-based workouts and endurance exercises have unique genetic markers. Some of these genes may also impact your health, such as your risk of heart disease, so carefully review each gene below to get a full understanding of your muscles and health. \",\n \"about\": \"

Muscle Hypertrophy: Growth

\\n\\nGenerally speaking, resistance training will improve the size of your muscles. However, your DNA will change how effectively your muscles respond to exercise. For some people, muscles will grow significantly more (muscle hypertrophy) in response to weight training.\\n\\nOther people may experience greater benefits from endurance activities and high-rep exercises.\\n\\nThis section of your DNA report will tell you how your muscles grow in response to certain exercises. \",\n \"caption\": \"How Muscle Hypertrophy (Growth) Works for You\",\n \"refreances\": [\n \"1. Ahmetov, I. I., Hakimullina, A. M., Lyubaeva, E. V., Vinogradova, O. L., & Rogozkin, V. A. (2008). Effect of HIF1A gene polymorphism on human muscle performance. Bulletin of Experimental Biology and Medicine, 146(3), 351–353. https://doi.org/10.1007/s10517-008-0291-3 \",\n \"2. Döring, F., Onur, S., Fischer, A., Boulay, M. R., Pérusse, L., Rankinen, T., Rauramaa, R., Wolfarth, B., & Bouchard, C. (2010). A common haplotype and the Pro582Ser polymorphism of the hypoxia-inducible factor-1α (HIF1A) gene in elite endurance athletes. Journal of Applied Physiology, 108(6), 1497–1500. https://doi.org/10.1152/japplphysiol.01165.2009 \",\n \"3. Gomez-Gallego, F., Santiago, C., González-Freire, M., Yvert, T., Muniesa, C. A., Serratosa, L., Altmäe, S., Ruiz, J. R., & Lucia, A. (2009). The C allele of the AGT Met235Thr polymorphism is associated with power sports performance. Applied Physiology, Nutrition, and Metabolism, 34(6), 1108–1111. https://doi.org/10.1139/h09-108 \",\n \"4. Petr, M., Št‘astný, P., Pecha, O., Šteffl, M., Šeda, O., & Kohlíková, E. (2014). PPARA Intron Polymorphism Associated with Power Performance in 30-s Anaerobic Wingate Test. PLoS ONE, 9(9), e107171. https://doi.org/10.1371/journal.pone.0107171 \",\n \"5. Zarębska, A., Sawczyn, S., Kaczmarczyk, M., Ficek, K., Maciejewska-Karłowska, A., Sawczuk, M., LeoŃska-Duniec, A., Eider, J., Grenda, A., & Cięszczyk, P. (2013). Association of rs699 (M235T) Polymorphism in the AGT Gene With Power but Not Endurance Athlete Status. Journal of Strength and Conditioning Research, 27(10), 2898–2903. \"\n ],\n \"GENES\": {\n \"PPARA\": {\n \"rs4253778\": {\n \"genotype\": \"CG\",\n \"effect_allels\": 1\n }\n },\n \"AGT\": {\n \"rs699\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"HIF1A\": {\n \"rs11549465\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Energy Balance & Production\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\\t\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your result is correlated with decreases in energy and expenditure (metabolism).\",\n \"risk_management\": \"You are at risk for disrupted energy production and balance. Your ATP (the energy used by cells) is likely to be low, and your adipocytes (fat cells) are more likely to be energy-storing (rather than energy-expending), causing your body to gain fat with fewer calories. You may need to exercise more in order to condition your metabolism to be more effective. Optimizing your nutrition will also prove useful for your physique and health.\\n\\nTo manage the risk of energy imbalance, you need to have an active lifestyle with regular exercise. Otherwise, you'll likely experience low energy levels and higher body fat. To release the energy stored in fat cells, a combination of cardio and resistance training should be used. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"

Energy Balance and Thermogenesis

\\n\\nThe three genes in this report identify your ability to burn calorie reserves to produce body heat, as well as your body's energy production.\\n\\nThese genes influence your innate ability to process calories and produce energy. This information can help you design an effective weight loss plan for your unique body. \",\n \"about\": \"The way your body consumes energy may have a positive or negative impact on your body weight.\\n\\nA slow metabolism (lower Resting Metabolic Rate) means your body needs fewer calories to maintain its weight.\\n\\nHowever, this can also lead to excess body fat, since it’s more difficult to maintain a calorie deficit.\\n\\nThese genes will determine how your body handles energy, calories, and your risk for obesity. \",\n \"caption\": \"Your natural energy usage\",\n \"refreances\": [\n \"1.\\tAlbuquerque, D., Nóbrega, C., & Manco, L. (2013). Association of FTO Polymorphisms with Obesity and Obesity-Related Outcomes in Portuguese Children. PLoS ONE, 8(1), e54370. https://doi.org/10.1371/journal.pone.0054370 \",\n \"2.\\tClaussnitzer, M., Dankel, S. N., Kim, K.-H., Quon, G., Meuleman, W., Haugen, C., Glunk, V., Sousa, I. S., Beaudry, J. L., Puviindran, V., Abdennur, N. A., Liu, J., Svensson, P.-A., Hsu, Y.-H., Drucker, D. J., Mellgren, G., Hui, C.-C., Hauner, H., & Kellis, M. (2015). FTO Obesity Variant Circuitry and Adipocyte Browning in Humans. New England Journal of Medicine, 373(10), 895–907. https://doi.org/10.1056/nejmoa1502214 \",\n \"3.\\tGenetta, T., Morisaki, H., Morisaki, T., & Holmes, E. W. (2001). A Novel Bipartite Intronic Splicing Enhancer Promotes the Inclusion of a Mini-exon in the AMP Deaminase 1 Gene. Journal of Biological Chemistry, 276(27), 25589–25597. https://doi.org/10.1074/jbc.m011637200 \",\n \"4.\\tNagai, N., Sakane, N., Tsuzaki, K., & Moritani, T. (2010). UCP1 genetic polymorphism (–3826 A/G) diminishes resting energy expenditure and thermoregulatory sympathetic nervous system activity in young females. International Journal of Obesity, 35(8), 1050–1055. https://doi.org/10.1038/ijo.2010.261 \",\n \"5.\\tNishimura, T., Katsumura, T., Motoi, M., Oota, H., & Watanuki, S. (2017). Experimental evidence reveals the UCP1 genotype changes the oxygen consumption attributed to non-shivering thermogenesis in humans. Scientific Reports, 7(1), 5570. https://doi.org/10.1038/s41598-017-05766-3\"\n ],\n \"GENES\": {\n \"FTO\": {\n \"rs1421085\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"AMPD1\": {\n \"rs17602729\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Metabolic Rate and Metabolic Syndrome\": {\n \"result_options\": [\n \"LOW\",\n \"INTEREMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your result is correlated with a low risk of metabolic syndrome and high rate of metabolism.\",\n \"risk_management\": \"Metabolic syndrome is a combination of conditions that increase your risk for heart disease, stroke, and type 2 diabetes. Preventing metabolic syndrome is certainly possible, no matter what your genes indicate here. \\n\\nMaintaining a healthy waist circumference, blood pressure, and cholesterol levels reduce your risk for metabolic syndrome. Exercise and weight loss can aid in these efforts and decrease insulin resistance. Eat a healthy diet that includes fruits, vegetables, and whole grains. Regular physical activity will reduce your blood pressure, blood sugar, and cholesterol levels. The key is to try to maintain a healthy weight. Early diagnosis and treatment will reduce health complications over the long term. Doctors can test for the risk factors where the presence of three or more symptoms indicate the presence of metabolic syndrome. However, if you experience the signs and symptoms and you have the risk factors, then it's best to ask for an optimized diet plan and training program for preventing or managing this condition. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Calculating Your Metabolism and Obesity Risk\\n\\nThe genes in this section of your report have been found to either increase or decrease your risk for obesity, metabolism, and BMI. Together, they create a picture of your genetic predisposition to weight loss during exercise. \",\n \"about\": \"

Your Metabolism

\\n\\n\\\"Metabolism\\\" is a general term for the processing of nutrients. In this particular report, our focus is on fat metabolism and how it affects your rate of weight loss during exercises. \\n\\nA slow metabolism can result in a higher body fat, even with the same diet and exercise plan as someone with a more effective metabolism. These genes will help you understand your body's predisposition to obesity. However, with consistent exercise, it is possible to improve your body's metabolism and maintain a great physique. \",\n \"caption\": \"Metabolism and obesity risk\",\n \"refreances\": [\n \"1.\\tBrondani, L. A., Assmann, T. S., de Souza, B. M., Bouças, A. P., Canani, L. H., & Crispim, D. (2014). Meta-Analysis Reveals the Association of Common Variants in the Uncoupling Protein (UCP) 1–3 Genes with Body Mass Index Variability. PLoS ONE, 9(5), e96411. https://doi.org/10.1371/journal.pone.0096411 \",\n \"2.\\tCorella, D., Arnett, D. K., Tsai, M. Y., Kabagambe, E. K., Peacock, J. M., Hixson, J. E., Straka, R. J., Province, M., Lai, C.-Q., Parnell, L. D., Borecki, I., & Ordovas, J. M. (2007). The −256T>C Polymorphism in the Apolipoprotein A-II Gene Promoter Is Associated with Body Mass Index and Food Intake in the Genetics of Lipid Lowering Drugs and Diet Network Study. Clinical Chemistry, 53(6), 1144–1152. https://doi.org/10.1373/clinchem.2006.084863 \",\n \"3.\\tCorella, D., Lai, C.-Q., Demissie, S., Cupples, L. A., Manning, A. K., Tucker, K. L., & Ordovas, J. M. (2007). APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study. Journal of Molecular Medicine, 85(2), 119–128. https://doi.org/10.1007/s00109-006-0147-0 \",\n \"4.\\tMcCormack, S., & Grant, S. F. A. (2013). Genetics of Obesity and Type 2 Diabetes in African Americans. Journal of Obesity, 2013, 1–12. https://doi.org/10.1155/2013/396416 \",\n \"5.\\tPark, S., Daily, J. W., Zhang, X., Jin, H. S., Lee, H. J., & Lee, Y. H. (2016). Interactions with the MC4R rs17782313 variant, mental stress and energy intake and the risk of obesity in Genome Epidemiology Study. Nutrition & Metabolism, 13(1), 1–10. https://doi.org/10.1186/s12986-016-0096-8 \",\n \"6.\\tSailer, C., Schmid, V., Fritsche, L., Gerter, T., Machicao, F., Niess, A., Häring, H.-U., Stefan, N., Fritsche, A., & Heni, M. (2016). FTO Genotype Interacts with Improvement in Aerobic Fitness on Body Weight Loss During Lifestyle Intervention. Obesity Facts, 9(3), 174–181. https://doi.org/10.1159/000444145 \",\n \"7.\\tTan, L.-J., Zhu, H., He, H., Wu, K.-H., Li, J., Chen, X.-D., Zhang, J.-G., Shen, H., Tian, Q., Krousel-Wood, M., Papasian, C. J., Bouchard, C., Pérusse, L., & Deng, H.-W. (2014). Replication of 6 Obesity Genes in a Meta-Analysis of Genome-Wide Association Studies from Diverse Ancestries. PLoS ONE, 9(5), e96149. https://doi.org/10.1371/journal.pone.0096149 \",\n \"8.\\tVargas, V. R. A., Bonatto, S. L., Macagnan, F. E., Feoli, A. M. P., Alho, C. S., Santos, N. D. V., & Schmitt, V. M. (2013). Influence of the 48867A>C (Asp358Ala) IL6R polymorphism on response to a lifestyle modification intervention in individuals with metabolic syndrome. Genetics and Molecular Research, 12(3), 3983–3991. https://doi.org/10.4238/2013.february.28.8 \",\n \"9.\\tZhu, W., Wang, C., Liang, L., Shen, Z., Fu, J., Liu, P., Lv, L., & Zhu, Y. (2014). Triglyceride-raising APOA5 genetic variants are associated with obesity and non-HDL-C in Chinese children and adolescents. Lipids in Health and Disease, 13(1), 93. https://doi.org/10.1186/1476-511x-13-93\"\n ],\n \"GENES\": {\n \"UCP2\": {\n \"rs659366\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"PPARD\": {\n \"rs2016520\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"APOA2\": {\n \"rs5082\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"APOA5\": {\n \"rs662799\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"FAM120AOS\": {\n \"rs944990\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"FTO\": {\n \"rs17817449\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"MC4R\": {\n \"rs17782313\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Lactate Clearance\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your result is correlated with a intermediate ability for lactate clearance. You have medium risk for lactate-related muscle injuries and are likely to have normal oxygen delivery to the muscles during physical activity.\",\n \"risk_management\": \"The accumulation of lactic acid in the muscles makes them less efficient, causes fatigue and a burning sensation, and negatively affects athletic performance. \\n\\nTo combat low lactate-clearance ability:\\n\\nAlways stay hydrated. Research has shown that sports drinks with dissolved oxygen concentrations or oxygen supplements significantly enhance post-exercise recovery through increased lactate clearance. \\n\\nPerform regular, moderately difficult exercise - over time, your lactate clearance ability will improve. \\n\\nPrevent muscle cramps by always stretching during your warmup and cooldown. Relieve sore muscles when they occur. \\n\\nTraining programs to improve lactate clearance include: sprint intervals; tempo runs; threshold training; and long slow distance training. In terms of bodybuilding, superior muscle growth is observed with slower lifting; however, low lactate clearance can make this more difficult. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"These genes will determine how well your body clears out lactate from your muscles, and may give you an indication of muscle soreness after exercise. It can also help you to optimize your time under tension (TUT) during workouts.\",\n \"about\": \"

Lactate Clearance: Oxygen Delivery and Anaerobic Metabolism During Exercise

\\n\\nDuring intense exercise, the oxygen in muscles runs out, and your body produces the substance \\\"lactate,\\\" which can be converted to energy without using oxygen. However, depending on your body's rate of producing and consuming it, lactate may build up to excess levels, causing muscle soreness and cramps. After exercise, it clears out of the bloodstream. \\n\\nDepending on your results here, you may experience increased muscle pain from workouts. Regular exercise, pre- and post-workout exercises & warm-ups, and drinking plenty of water can help mitigate this problem. \",\n \"caption\": \"Muscle exhaustion and workout experience.\",\n \"refreances\": [\n \"1.\\tKikuchi, N., Fuku, N., Matsumoto, R., Matsumoto, S., Murakami, H., Miyachi, M., & Nakazato, K. (2016). The Association Between MCT1 T1470A Polymorphism and Power-Oriented Athletic Performance. International Journal of Sports Medicine, 38(01), 76–80. https://doi.org/10.1055/s-0042-117113 \",\n \"2.\\tMassidda, M., Eynon, N., Bachis, V., Corrias, L., Culigioni, C., Piras, F., Cugia, P., Scorcu, M., & Calò, C. M. (2015). Influence of the MCT1 rs1049434 on Indirect Muscle Disorders/Injuries in Elite Football Players. Sports Medicine - Open, 1(1), 1. https://doi.org/10.1186/s40798-015-0033-9 \",\n \"3.\\tTin, A., Balakrishnan, P., Beaty, T. H., Boerwinkle, E., Hoogeveen, R. C., Young, J. H., & Kao, W. H. L. (2015). GCKRandPPP1R3Bidentified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study. Diabetic Medicine, 33(7), 968–975. https://doi.org/10.1111/dme.12971\"\n ],\n \"GENES\": {\n \"MCT1\": {\n \"rs1049434\": {\n \"genotype\": \"AT\",\n \"effect_allels\": 1\n }\n },\n \"GCKR\": {\n \"rs1260326\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"PPP1R3B/ LOC157273\": {\n \"rs9987289\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Aerobic Capacity\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"You will likely experience an intermediate improvement in your VO2max in response to exercise.\",\n \"risk_management\": \"You should never smoke cigarettes, including e-cigarettes and Juuls. If you currently do smoke, it's important to quit immediately. \\n\\nIf your job requires frequent contact with chemical fumes or gaseous irritants, speak with your supervisor about the best way to protect yourself. Bringing face masks in public places with too much smoke can also protect your respiratory system. \\n\\nNutritional support for healthy lungs includes fatty fish, which has omega-3 fatty acids, apples rich in phytochemicals, and tomatoes, which are a source of antioxidants. Regular aerobic exercise can help improve lung function and oxygen utilization (VO2max).\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"The genes in this report are critical to your aerobic ability. See how well you respond to aerobic exercise and get tips on whether you should incorporate more aerobic exercise into your daily routine.\",\n \"about\": \"Your VO2 Max reveals how well your body uses oxygen. \\n\\nYour body uses more oxygen during intense exercise. At some point, your body will not be able to increase its oxygen usage anymore. That breaking point is your VO2 Max, and it determines, in part, your aerobic abilities.\\n\\nPeople with low aerobic capacity may easily feel \\\"out of breath\\\" from exercise. When someone has reduced lung function, they may use a larger part of their \\\"breathing reserve\\\" (the maximum air capacity of your lungs, compared to the typical amount used for breathing in a resting state). Aerobic training can improve endurance and reduce breathlessness by increasing your aerobic capacity. \\n \\n \\n \\n \",\n \"caption\": \"Maximal Oxygen Uptake During Exercise\",\n \"refreances\": [\n \"1.\\tAhmetov, I. I., Khakimullina, A. M., Popov, D. V., Missina, S. S., Vinogradova, O. L., & Rogozkin, V. A. (2008). Polymorphism of the vascular endothelial growth factor gene (VEGF) and aerobic performance in athletes. Human Physiology, 34(4), 477–481. https://doi.org/10.1134/s0362119708040129 \",\n \"2.\\tAhmetov, I. I., Williams, A. G., Popov, D. V., Lyubaeva, E. V., Hakimullina, A. M., Fedotovskaya, O. N., Mozhayskaya, I. A., Vinogradova, O. L., Astratenkova, I. V., Montgomery, H. E., & Rogozkin, V. A. (2009). The combined impact of metabolic gene polymorphisms on elite endurance athlete status and related phenotypes. Human Genetics, 126(6), 751–761. https://doi.org/10.1007/s00439-009-0728-4 \",\n \"3.\\tAhmetov, I., Kulemin, N., Popov, D., Naumov, V., Akimov, E., Bravy, Y., Egorova, E., Galeeva, A., Generozov, E., Kostryukova, E., Larin, A., Mustafina, L., Ospanova, E., Pavlenko, A., Starnes, L., Żmijewski, P., Alexeev, D., Vinogradova, O., & Govorun, V. (2014). GENOME-WIDE ASSOCIATION STUDY IDENTIFIES THREE NOVEL GENETIC MARKERS ASSOCIATED WITH ELITE ENDURANCE PERFORMANCE . Biology of Sport, 32(1), 3–9. https://doi.org/10.5604/20831862.1124568 \",\n \"4.\\tArtigas, M. S., Wain, L. V., Miller, S., Kheirallah, A. K., Huffman, J. E., Ntalla, I., Shrine, N., Obeidat, M., Trochet, H., McArdle, W. L., Alves, A. C., Hui, J., Zhao, J. H., Joshi, P. K., Teumer, A., Albrecht, E., Imboden, M., Rawal, R., Lopez, L. M., … Tobin, M. D. (2015). Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nature Communications, 6(1), 1. https://doi.org/10.1038/ncomms9658 \",\n \"5.\\tGayagay, G., Yu, B., Hambly, B., Boston, T., Hahn, A., Celermajer, D. S., & Trent, R. J. (1998). Elite endurance athletes and the ACE I allele - the role of genes in athletic performance. Human Genetics, 103(1), 48–50. https://doi.org/10.1007/s004390050781\",\n \"6.\\tSteinbacher, P., Feichtinger, R. G., Kedenko, L., Kedenko, I., Reinhardt, S., Schönauer, A.-L., Leitner, I., Sänger, A. M., Stoiber, W., Kofler, B., Förster, H., Paulweber, B., & Ring-Dimitriou, S. (2015). The Single Nucleotide Polymorphism Gly482Ser in the PGC-1α Gene Impairs Exercise-Induced Slow-Twitch Muscle Fibre Transformation in Humans. PLOS ONE, 10(4), e0123881. https://doi.org/10.1371/journal.pone.0123881\"\n ],\n \"GENES\": {\n \"ACE\": {\n \"rs4343\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"ADRB2\": {\n \"rs1042713\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PPARGC1A\": {\n \"rs8192678\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"TSHR\": {\n \"rs7144481\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"RNU5F-1, LYPLAL1\": {\n \"rs4846603\": {\n \"genotype\": \"GT\",\n \"effect_allels\": 1\n }\n },\n \"RNU5F-1, LYPLAL2\": {\n \"rs2345493\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"RNU5F-1, LYPLAL3\": {\n \"rs7866525\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"RNU5F-1, LYPLAL6\": {\n \"rs705859\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Muscle Strength\": {\n \"result_options\": [\n \"LOW \",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"You may have an advantage when developing strength. Regular strength training and good nutrition can help you reach your full strength potential. \",\n \"risk_management\": \"Your result is associated with significant muscle strength. You may be able to perform power-oriented exercises very well, and you may gain significant benefits, like muscular hypertrophy, bone density, and overall physical fitness, in response to power training. \\n\\nConsistent and correct training will improve and maximize your strength through progressive overload resistance training. It is also important to note that other factors play a role in strength variability, including types of muscle fiber, age, gender, limb and muscle length, and point of tendon insertion. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"

Calculating Your Muscle Strength

\\n\\nMuscular strength is the amount of force a muscle is capable of producing with a single maximal effort during muscular contractions. These genes impact your muscles' inherent ability to perform sports with short bursts of power. Genetics influence your usual capacity, but muscular strength can be optimized and improved with good health and a smart exercise and diet program.\",\n \"about\": \"

Muscle Strength

\\n\\nMuscles are complex organs, and their genetics are complicated, too. \\n\\nWhile we tend to think of larger muscles as stronger muscles, there are some times when bigger muscle volume is related to lower overall muscle quality. \\n\\nThe genes in this report will help you understand how your muscles develop, as well as your natural inclination toward strength training. \",\n \"caption\": \"Muscles and Strength: Your genetic potential \",\n \"refreances\": [\n \"1.\\tEider, J., Ahmetov, I. I., Fedotovskaya, O. N., Moska, W., Cieszczyk, P., Zarebska, A., Czubek, Z., Klocek, T., Stepien-Slodkowska, M., Maciejewska-Karlowska, A., & Sawczuk, M. (2015a). CKM gene polymorphism in Russian and Polish rowers. Russian Journal of Genetics, 51(3), 318–321. https://doi.org/10.1134/s1022795415030023 \",\n \"2.\\tEider, J., Ahmetov, I. I., Fedotovskaya, O. N., Moska, W., Cieszczyk, P., Zarebska, A., Czubek, Z., Klocek, T., Stepien-Slodkowska, M., Maciejewska-Karlowska, A., & Sawczuk, M. (2015b). CKM gene polymorphism in Russian and Polish rowers. Russian Journal of Genetics, 51(3), 318–321. https://doi.org/10.1134/s1022795415030023 \",\n \"3.\\tKostek, M., Hubal, M. J., & Pescatello, L. S. (2010). The Role of Genetic Variation in Muscle Strength. American Journal of Lifestyle Medicine, 5(2), 156–170. https://doi.org/10.1177/1559827610387251 \",\n \"4.\\tPistilli, E. E., Devaney, J. M., Gordish-Dressman, H., Bradbury, M. K., Seip, R. L., Thompson, P. D., Angelopoulos, T. J., Clarkson, P. M., Moyna, N. M., Pescatello, L. S., Visich, P. S., Zoeller, R. F., Gordon, P. M., & Hoffman, E. P. (2008). Interleukin-15 and interleukin-15Rα SNPs and associations with muscle, bone, and predictors of the metabolic syndrome. Cytokine, 43(1), 45–53. https://doi.org/10.1016/j.cyto.2008.04.008 \",\n \"5.\\tRoth, S. M., Walsh, S., Liu, D., Metter, E. J., Ferrucci, L., & Hurley, B. F. (2007). The ACTN3 R577X nonsense allele is under-represented in elite-level strength athletes. European Journal of Human Genetics, 16(3), 391–394. https://doi.org/10.1038/sj.ejhg.5201964\"\n ],\n \"GENES\": {\n \"IL15RA\": {\n \"rs2228059\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"CKM\": {\n \"rs10415720\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"ACTN3\": {\n \"rs1815739\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Insulin Sensitivity and Exercise \": {\n \"result_options\": [\n \"LOW \",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Your result is correlated with increased insulin sensitivity in response to exercise.\",\n \"risk_management\": \"People with high insulin sensitivity are likely to require smaller amounts of insulin to lower blood glucose levels. Exercise reduces low insulin sensitivity. \\n\\nNutrition through a healthy diet and exercise program must be done to manage insulin resistance and avoid risks. Nutritional recommendations in improving insulin resistance are as follows: weight loss, restricting saturated fat to less than 7% of energy intake, restricting cholesterol to less than 200 mg/day, restricting trans fats in the diet, and consuming high levels of fiber (at least 14g/1,000 kcal). Other factors that modify your propensity toward insulin resistance are body weight, visceral fat, age, ethnicity, sleep, and smoking status. Doctors can diagnose prediabetes or diabetes with an A1C Test, fasting Blood Glucose test, or a Glucose Tolerance Test, which measures your blood sugar levels. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"

Insulin Resistance and Exercise

\\n\\nYour risk for diabetes and heart disease is increased with insulin resistance. \\n\\nExercise can improve your insulin resistance, but the effect may be less pronounced in some people because of their LIPC gene. \",\n \"about\": \"Insulin resistance is a serious risk factor for heart disease and diabetes.\\n\\nLower insulin sensitivity can sometimes be improved with exercise. If exercise is insufficient, you may consider implementing a more stringent diet in order to improve your insulin resistance.\",\n \"caption\": \"Reducing your risk of diabetes through exercise.\",\n \"refreances\": [\n \"1.\\tStefan, N., Thamer, C., Staiger, H., Machicao, F., Machann, J., Schick, F., Venter, C., Niess, A., Laakso, M., Fritsche, A., & Häring, H.-U. (2007). Genetic Variations in PPARD and PPARGC1A Determine Mitochondrial Function and Change in Aerobic Physical Fitness and Insulin Sensitivity during Lifestyle Intervention. The Journal of Clinical Endocrinology & Metabolism, 92(5), 1827–1833. https://doi.org/10.1210/jc.2006-1785 \",\n \"2.\\tTeran-Garcia, M., Santoro, N., Rankinen, T., Bergeron, J., Rice, T., Leon, A. S., Rao, D. C., Skinner, J. S., Bergman, R. N., Despres, J.-P., & Bouchard, C. (2005). Hepatic Lipase Gene Variant -514C>T Is Associated With Lipoprotein and Insulin Sensitivity Response to Regular Exercise: The HERITAGE Family Study. Diabetes, 54(7), 2251–2255. https://doi.org/10.2337/diabetes.54.7.2251\"\n ],\n \"GENES\": {\n \"LIPC\": {\n \"rs1800588\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"PPARD\": {\n \"rs2267668\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"PPARGC1A\": {\n \"rs8192678\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Motivation to exercise\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your genetic result is correlated with intermediate likelihood of being motivated for exercise\",\n \"risk_management\": \"Exercise probably doesn't boost your mood significantly, but you also don't suffer quite as much as other people during a workout. Regular exercise is important to your overall health, even if you don't enjoy it, and frequent workouts will allow you to adjust and adapt. In order to make exercise more fun, try incorporating more sports and group activities into your routine.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"

Understanding Your Love for Exercise

\\n\\nSome people just naturally love exercise. For others, it's a daily struggle to get into the gym.\\n\\nThe BDNF gene has been studied for its effects on people's desire for exercise. The sense of enjoyment and reward that people get from exercise can be improved with regular training, even if your genes haven't helped you get motivated. \",\n \"about\": \"Some people are naturally driven to exercise. Others have to work for it.\\n\\nSince exercise has many important health and cognitive benefits, having a sustained motivation to exercise can be a huge plus to your overall fitness results. This report will reveal how much your genes have helped (or hurt) you in your motivation to exercise. \",\n \"caption\": \"Naturally Driven - or Hard Working?\",\n \"refreances\": [\n \"1.\\tCaldwell Hooper, A. E., Bryan, A. D., & Hagger, M. S. (2014). What keeps a body moving? The brain-derived neurotrophic factor val66met polymorphism and intrinsic motivation to exercise in humans. Journal of Behavioral Medicine, 37(6), 1180–1192. https://doi.org/10.1007/s10865-014-9567-4 \",\n \"2.\\tGuidry, M. A., Kostek, M. A., Angelopoulos, T. J., Clarkson, P. M., Gordon, P. M., Moyna, N. M., Visich, P. S., Zoeller, R. F., Thompson, P. D., Devaney, J. M., Gordish-Dressman, H., Hoffman, E. P., & Pescatello, L. S. (2012). Endothelial Nitric Oxide Synthase (NOS3) +894 G>T Associates with Physical Activity and Muscle Performance among Young Adults. ISRN Vascular Medicine, 2012, 1–7. https://doi.org/10.5402/2012/901801\"\n ],\n \"GENES\": {\n \"BDNF\": {\n \"rs6265\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Exercise Heart Rate Profile\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Your result is correlated with a much faster heart rate recovery\",\n \"risk_management\": \"Your heart responds quickly to exercise. Warming up may not be as critical for you, but it can still improve your performance and overall health. To calculate your actual heart rate recovery at the end of a bout of exercise, find your pulse and calculate your heart rate: Place one or two fingertips (not a thumb) on the opposite wrist, just below the base of your thumb. Count the number of heartbeats you feel in 10 seconds. Multiply that number by six to get your heart rate per minute. Take your heart rate both during exercise and one minute after stopping. Subtract the two numbers to get your heart rate recovery.\\n\\nA recovery heart rate of 25 to 30 beats in one minute is a good score, and 50 to 60 beats in one minute is considered excellent. You should monitor your one-minute and two-minute recovery heart rate at least twice weekly to gauge whether your fitness level is improving. You may take advantage of a fitness watch or heart rate monitoring devices if you dislike manual counting with clocks. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"

Calculating Your Heart Rate Response to Exercise

\\n\\nOver a dozen different genes and SNPs are implicated in the way your heart rate increases and recovers from exercise. \\n\\nWhile a slower heart rate response is not necessarily bad, it may require you to warm up more thoroughly before exercise in order to maximize your performance and overall health. \",\n \"about\": \"

Your Heart’s Response to Exercise.

\\n\\nDepending on your genetics, your heart may respond more slowly to exercise. Your heart’s response not only refers to how quickly it speeds up during exercise, but how quickly it recovers when you're done. Heart rate (HR) responds to exercise by increasing during exercise and lowering after exercise. HR is an important predictor of mortality, which researchers believe is modulated by the autonomic nervous system.\\n\\nIn one study, the genes we believe are responsible for heart rate recovery were also tied to neuron biology. This suggests that the nervous system is critically involved in your heart rate and heart health.\",\n \"caption\": \"How Your Heart Rate Recovers After a Workout\",\n \"refreances\": [\n \"1.\\tden Hoed, M., Eijgelsheim, M., Esko, T., Brundel, B. J. J. M., Peal, D. S., Evans, D. M., Nolte, I. M., Segrè, A. V., Holm, H., Handsaker, R. E., Westra, H.-J., Johnson, T., Isaacs, A., Yang, J., Lundby, A., Zhao, J. H., Kim, Y. J., Go, M. J., Almgren, P., … Loos, R. J. F. (2013). Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics, 45(6), 621–631. https://doi.org/10.1038/ng.2610 \",\n \"2.\\tEijgelsheim, M., Newton-Cheh, C., Sotoodehnia, N., de Bakker, P. I. W., Muller, M., Morrison, A. C., Smith, A. V., Isaacs, A., Sanna, S., Dorr, M., Navarro, P., Fuchsberger, C., Nolte, I. M., de Geus, E. J. C., Estrada, K., Hwang, S.-J., Bis, J. C., Ruckert, I.-M., Alonso, A., … O’Donnell, C. J. (2010). Genome-wide association analysis identifies multiple loci related to resting heart rate. Human Molecular Genetics, 19(19), 3885–3894. https://doi.org/10.1093/hmg/ddq303 \",\n \"3.\\tVerweij, N., van de Vegte, Y. J., & van der Harst, P. (2018). Genetic study links components of the autonomous nervous system to heart-rate profile during exercise. Nature Communications, 9(1), 898. https://doi.org/10.1038/s41467-018-03395-6\"\n ],\n \"GENES\": {\n \"ACHE\": {\n \"rs314370\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"PAX2\": {\n \"rs10883543\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"CHRM2\": {\n \"rs10488600\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"RNF220\": {\n \"rs272564\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"CAV1\": {\n \"rs11773845\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"PRDM6\": {\n \"rs151283\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n },\n \"GRIK2\": {\n \"rs2224202\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"GJA1\": {\n \"rs9398652\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"ADRB1\": {\n \"rs1801253\": {\n \"genotype\": \"GC\",\n \"effect_allels\": 1\n }\n },\n \"SCN5a\": {\n \"rs1805124\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"CASQ1 Intron 2\": {\n \"rs617698\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Injury Predisposition\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your result is correlated with intermediate genetic risk of injury as a result of exercise.\",\n \"risk_management\": \"You don't have an increased risk of injury, but anyone can get injured when pushed too far. It is always recommended that you perform exercises with the correct form to avoid injuries. Continuous strength training makes the body adapt with muscular growth, increased tendon strength, and higher bone density. Muscle contractions stimulate tendons and ligaments to become stronger and thicker over time, but since your genetic risk for tendinopathy and muscle damage is low, you should not experience these issues unless pushed beyond your limit. Warm up with 5-10 minutes of aerobics or low-intensity resistance training and stretch for 5 minutes after your workout.\\n\\nIt takes roughly 10 weeks of regular resistance exercise to strengthen the tendons, but it takes longer for them to become thicker. Research has shown that regular training can increase the strength and thickness of tendons by up to 20%. Other factors that can modify this genetic predisposition are nutrition, lifestyle, training plan, anatomical features, and more.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"

Understand Your Risk for Injury

\\n\\nSome genes, like the COL1A1 gene, impact your risk of injury to tendons and ligaments. Those connective tissues are injured more easily than bones, and the injuries can be quite painful. The classic Achilles Heel injury is just one example of a serious tendon injury.\\n\\nWe've also analyzed genes that may increase your levels of inflammation and recovery times after exercise. \",\n \"about\": \"

Avoid Injuries Caused by Exercise

\\n\\nInflammation, tendonitis, and pain can all slow you down, preventing you from reaching your goals (and possibly leaving you on the couch for weeks or months).\\n\\nTaking healthy precautions, such as stretching regularly, staying hydrated, and warming up before exercise, can help you avoid injuries.\\n\\nYour genetic profile only reveals your risk of injury compared to other people: making healthy choices and training smarter will be more important in preventing the weakening and rupture of tendons and permanent damage to your body.\",\n \"caption\": \"Your risk of injury during a workout\",\n \"refreances\": [\n \"1.\\tBaumert, P., Lake, M. J., Stewart, C. E., Drust, B., & Erskine, R. M. (2016). Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing. European Journal of Applied Physiology, 116(9), 1595–1625. https://doi.org/10.1007/s00421-016-3411-1 \",\n \"2.\\tGalasso, O., Iaccino, E., Gallelli, L., Perrotta, I., Conforti, F., Donato, G., & Gasparini, G. (2012). Collagen Type V Polymorphism in Spontaneous Quadriceps Tendon Ruptures. Orthopedics, 35(4), e580–e584. https://doi.org/10.3928/01477447-20120327-31 \",\n \"3.\\tGalicia, J. C., Tai, H., Komatsu, Y., Shimada, Y., Akazawa, K., & Yoshie, H. (2004). Polymorphisms in the IL-6 receptor (IL-6R) gene: strong evidence that serum levels of soluble IL-6R are genetically influenced. Genes & Immunity, 5(6), 513–516. https://doi.org/10.1038/sj.gene.6364120 \",\n \"4.\\tJeremić, V., Alempijević, T., Mijatović, S., Šijački, A., Dragašević, S., Pavlović, S., Miličić, B., & Krstić, S. (2014). Clinical relevance of IL-6 gene polymorphism in severely injured patients. Bosnian Journal of Basic Medical Sciences, 14(2), 110. https://doi.org/10.17305/bjbms.2014.2274 \",\n \"5.\\tLiu, C., Jin, P., Luo, Y., Xu, J., Kong, C., Chen, J., Xie, H., & Zhou, G. (2018). Association of Single-Nucleotide Polymorphisms of C-Reactive Protein Gene with Susceptibility to Infantile Sepsis in Southern China. Medical Science Monitor, 24, 590–595. https://doi.org/10.12659/msm.908602 \",\n \"6.\\tRaleigh, S. M., van der Merwe, L., Ribbans, W. J., Smith, R. K. W., Schwellnus, M. P., & Collins, M. (2008). Variants within the MMP3 gene are associated with Achilles tendinopathy: possible interaction with the COL5A1 gene. British Journal of Sports Medicine, 43(7), 514–520. https://doi.org/10.1136/bjsm.2008.053892 \",\n \"7.\\tRaleigh, S., Posthumus, M., O’Cuinneagain, D., van der Merwe, W., & Collins, M. (2012). The GDF5 Gene and Anterior Cruciate Ligament Rupture. International Journal of Sports Medicine, 34(04), 364–367. https://doi.org/10.1055/s-0032-1316361 \",\n \"8.\\tWang, C., Li, H., Chen, K., Wu, B., & Liu, H. (2017). Association of polymorphisms rs1800012 in COL1A1 with sports-related tendon and ligament injuries: a meta-analysis. Oncotarget, 8(16), 27627–27634. https://doi.org/10.18632/oncotarget.15271\"\n ],\n \"GENES\": {\n \"GDF5\": {\n \"rs143383\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"COL1A1\": {\n \"rs1800012\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"COL5A1\": {\n \"rs12722\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"IL6\": {\n \"rs1800795\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"IL6R\": {\n \"rs2228145\": {\n \"genotype\": \"CA\",\n \"effect_allels\": 1\n }\n },\n \"CRP\": {\n \"rs1205\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"TNF\": {\n \"rs1800629\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"MMP3\": {\n \"rs679620\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Hand grip strength\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your genes are correlated with a intermediate level of hand grip strength.\",\n \"risk_management\": \"You may not have a reduced level of hand grip strength, but your overall fitness and muscular health are critical: progressive resistance training is highly recommended. Other exercises to improve grip strength are as follows: wrist flexor stretches; wrist extensor stretches; thumb flexion and extension; and wrist ulnar/radial deviation. Hand grip strengthening workout tools can also be purchased. Dietary supplements with high protein and oral Vitamin D supplements can also help. \\n\\nA dynamometer is a piece of equipment used to test hand grip strength, using either pounds (Ibs) or kilograms (kg) of squeezing force. The quality of your results is highly dependent on age and sex. \",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Hand grip strength is a widely used proxy for muscular fitness and a predictor of many possible causes of death. However, improving your hand grip strength on its own will not necessarily improve your health: your overall fitness is more important, and hand grip strength is merely an indicator of your overall health.\",\n \"about\": \"Hand grip strength is a surprisingly useful measure of your overall strength: hand grip strength (HGS) tests are commonly used as an indicator of overall muscle strength in medical and sports practices. \\n\\nLow hand grip strength is a risk factor of osteoporosis, a disease where bone density and bone quality is reduced. Generally, grip strength is a marker of frailty and sarcopenia (loss of muscle mass and quality) and a simple indicator for all-cause mortality. If your grip strength appears to be decreasing, consult your physician.\",\n \"caption\": \"How strong are your hands and forearms? \",\n \"refreances\": [\n \"1.\\tWillems, S. M., Wright, D. J., Day, F. R., Trajanoska, K., Joshi, P. K., Morris, J. A., Matteini, A. M., Garton, F. C., Grarup, N., Oskolkov, N., Thalamuthu, A., Mangino, M., Liu, J., Demirkan, A., Lek, M., Xu, L., Wang, G., Oldmeadow, C., Gaulton, K. J., … Scott, R. A. (2017). Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Nature Communications, 8(1), 16015. https://doi.org/10.1038/ncomms16015\"\n ],\n \"GENES\": {\n \"GLIS1\": {\n \"rs4926611\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"ERP27, C12orf60\": {\n \"rs11614333\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"SYT1\": {\n \"rs6539284\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"TGFA\": {\n \"rs1807968\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"KANSL1\": {\n \"rs17577094\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"HOXB3, HOXB-AS3\": {\n \"rs2288278\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"GBF1\": {\n \"rs2273555\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"FAM3C, PTPRZ1\": {\n \"rs1406195\": {\n \"genotype\": \"CA\",\n \"effect_allels\": 1\n }\n },\n \"CSMD1, LOC100287015\": {\n \"rs9987312\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"LINC00968, IMPAD1\": {\n \"rs1508086\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"BMS1L, LINC01264\": {\n \"rs3121324\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Bone density and fracture risk\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\\t\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"High risk for bone fractures\",\n \"risk_management\": \"Because of your increased risk, it's extremely important to begin taking care of your bones as early as possible. \\n\\nExercise is highly recommended to improve your bone mineral density. Weight-bearing exercises help build bones, increase bone mineral density, and reduce the risk of osteoporosis. Some exercises linked to increased bone mineral density include: weight training; squats; plyometrics (jumping); running up and down stairs; and high-impact aerobics.\\n\\nThe most important factors in building bone density are:\\n\\n(a) a high magnitude of muscle strain, e.g., lifting heavy weights.\\n(b) a high rate of muscle strain, like from tennis and plyometrics (jumping exercises).\\n(c) the frequency at which the muscle strains occur, like when running and moving constantly.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"These genes will let you know if you are more likely to have lower bone density with an increased risk of fracture. The correct exercises can help reduce this risk.\",\n \"about\": \"Bone density refers to the levels of mineral deposits per unit of volume (or the surface area) of a bone. These deposits are called \\\"hydroxyapatite,\\\" a mineral form of calcium apatite. Bone density is a good indicator of your risk of having a fracture or bone breakage. It can also impact your ability to perform weight training safely and effectively.\",\n \"caption\": \"How strong are your bones?\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\",\n \"refreances\": [\n \"1.\\tKim, S. K. (2018). Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture. PLOS ONE, 13(7), e0200785. https://doi.org/10.1371/journal.pone.0200785\"\n ],\n \"GENES\": {\n \"SLC8A1\": {\n \"rs10490046\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n },\n \"RSPO3\": {\n \"rs9491697\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"AQP1\": {\n \"rs10276670\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"STARD3NL\": {\n \"rs6974574\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"WNT16\": {\n \"rs2908007\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"MBL2\": {\n \"rs12416665\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"TMEM135\": {\n \"rs597319\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"SOST\": {\n \"rs4792909\": {\n \"genotype\": \"GT\",\n \"effect_allels\": 1\n }\n },\n \"FAM210A\": {\n \"rs4796995\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"LINC01700\": {\n \"rs2836789\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Testosterone\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE \",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your genetic result is correlated to a high risk of reduced levels of testosterone.\",\n \"risk_management\": \"In general, the normal range of testosterone in males is about 270-1070 ng/dL with an average level of 679 ng/dL. Testosterone levels peak at about age 20, and then it slowly declines. If a man has levels outside this range, an imbalance occurs that can lead to problematic health conditions. \\n\\nTo increase testosterone levels naturally, here are our recommendations: \\n\\n* Exercise and lift weights regularly in a strength training program\\n* Eat a balanced diet\\n* Take a Vitamin D supplement \\n* Schedule 8 hours of good quality sleep every night.\\n\\nSteroids are heavily discouraged because they result in impotence, testicle degeneration, hair loss, acne, heart attack risk, and behavioral changes. Natural testosterone production optimized through resistance training is beneficial to your overall health. Natural testosterone production in the body is stimulated by and involved in muscle gain and recovery. If you are exposed to high-stress environments, changes in lifestyle to reduce stress can have positive effects on your testosterone level. Blood testosterone tests are available in clinics to see if your genetic predisposition has manifested.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"

Calculating Your Testosterone

\\n\\nThese genes are associated with testosterone levels in varying amounts. Combined, they give a general picture of your testosterone production and maintenance. \",\n \"about\": \"

Testosterone: Sex and Muscle Hormone

\\n\\nTestosterone is known as the male sex hormone, but it has many non-reproductive benefits as well. Testosterone is associated with increased muscle mass and improved fat distribution. \\n\\nLow testosterone can have many causes, including type 2 diabetes, obesity, and certain medications. There are also genetic components that may affect your levels of testosterone. Note though that the information here is only applicable to men.\",\n \"caption\": \"Muscle and Growth: Understanding Testosterone\",\n \"refreances\": [\n \"1.\\tEriksson, A. L., Lorentzon, M., Mellström, D., Vandenput, L., Swanson, C., Andersson, N., Hammond, G. L., Jakobsson, J., Rane, A., Orwoll, E. S., Ljunggren, O. ̈., Johnell, O., Labrie, F., Windahl, S. H., & Ohlsson, C. (2006). SHBG Gene Promoter Polymorphisms in Men Are Associated with Serum Sex Hormone-Binding Globulin, Androgen and Androgen Metabolite Levels, and Hip Bone Mineral Density. The Journal of Clinical Endocrinology & Metabolism, 91(12), 5029–5037. https://doi.org/10.1210/jc.2006-0679 \",\n \"2.\\tLow, Y.-L., Taylor, J. I., Grace, P. B., Dowsett, M., Folkerd, E., Doody, D., Dunning, A. M., Scollen, S., Mulligan, A. A., Welch, A. A., Luben, R. N., Khaw, K.-T., Day, N. E., Wareham, N. J., & Bingham, S. A. (2005). Polymorphisms in the CYP19 Gene May Affect the Positive Correlations between Serum and Urine Phytoestrogen Metabolites and Plasma Androgen Concentrations in Men. The Journal of Nutrition, 135(11), 2680–2686. https://doi.org/10.1093/jn/135.11.2680 \",\n \"3.\\tOhlsson, C., Wallaschofski, H., Lunetta, K. L., Stolk, L., Perry, J. R. B., Koster, A., Petersen, A.-K., Eriksson, J., Lehtimäki, T., Huhtaniemi, I. T., Hammond, G. L., Maggio, M., Coviello, A. D., Ferrucci, L., Heier, M., Hofman, A., Holliday, K. L., Jansson, J.-O., Kähönen, M., … Haring, R. (2011). Genetic Determinants of Serum Testosterone Concentrations in Men. PLoS Genetics, 7(10), e1002313. https://doi.org/10.1371/journal.pgen.1002313\"\n ],\n \"GENES\": {\n \"SHBG_1\": {\n \"rs1799941\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"SHGB_2\": {\n \"rs6258\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"FAM9B\": {\n \"rs5934505\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Leisure time exercise or physical activity\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE \",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE \",\n \"result_description\": \"You have a intermediate genetic likelihood of leisure-time activity. You may need to create a schedule that incorporates more exercise in order to remain healthy, since this activity does not come naturally to you.\",\n \"risk_management\": \"You may not naturally exercise as much as you should, so follow these guidelines to create a healthier schedule and lifestyle:\\n\\n1) Adults should perform at least 150 minutes of moderate-intensity aerobic physical activity throughout the week. If you're short on time, at least 75 minutes of vigorous-intensity aerobic physical activity each week is sufficient.\\n2) Aerobic activity should be performed in bouts of at least 10 minutes. Exercise that lasts less than 10 minutes may not have a significant impact on your health.\\n3) For additional health benefits, adults should increase their moderate-intensity aerobic activity to 300 minutes per week, or engage in 150 minutes of vigorous-intensity aerobic physical activity per week.\\n4) Muscular strength training should be done at least twice a week, incorporating large muscles and whole-body movements, such as deadlifts, bench presses, and squats.\\n\\nThese recommendations are relevant to all healthy adults, ages 18 to 64, unless specific medical conditions suggest otherwise. The World Health Organization (WHO) also warns that pregnant women, postpartum women, and people with cardiac events may need to take extra precautions and seek medical advice before striving to achieve the recommended levels of physical activity for this age group.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"These genes are known to impact the level of exercise a person will naturally seek out during the course of a week. \",\n \"about\": \"Many studies have shown that physical activity reduces the risks of all-cause mortality, coronary heart disease, hypertension (high blood pressure), stroke, metabolic syndrome, type 2 diabetes, breast cancer, colon cancer, and depression, and a lack of exercise causes millions of premature deaths worldwide.\\n\\nPhysical activity can be broken down into light, moderate, and vigorous intensity. We measure these activities in METs (metabolic equivalents). Sitting quietly is worth 1 MET. Vigorous activities are those that cause a person to breathe more heavily than normal, to the point that they cannot talk, and is worth 8 METs. Moderate activities are those that cause a person to breathe more heavily than normal, worth 4 METs. Light activities are those for which a person can still breathe normally (e.g. walking), worth 3.3 METs. \\n\\nMore than 4 MET hours per week is considered \\\"leisure-time exercise behavior.\\\" In other words, if you work up a sweat and have to breathe more forcefully for at least 4 hours a week, you are participating in leisure-time physical activity. Most people do not engage in any leisure-time physical activity, which is a serious health risk. The genes we've analyzed here contribute to your likelihood of leisure-time exercise, but all people are encouraged to move around and increase their heart rates and breathing frequently.\",\n \"caption\": \"Do you stay active outside the gym?\",\n \"refreances\": [\n \"1.\\tHara, M., Hachiya, T., Sutoh, Y., Matsuo, K., Nishida, Y., Shimanoe, C., Tanaka, K., Shimizu, A., Ohnaka, K., Kawaguchi, T., Oze, I., Matsuda, F., Ito, H., Kawai, S., Hishida, A., Okada, R., Sasakabe, T., Hirata, A., Ibusuki, R., Nindita, Y., … Wakai, K. (2018). Genomewide Association Study of Leisure-Time Exercise Behavior in Japanese Adults. Medicine and science in sports and exercise, 50(12), 2433–2441. https://doi.org/10.1249/MSS.0000000000001712\"\n ],\n \"GENES\": {\n \"NPSR1–DPY19L1 \": {\n \"rs10252228\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"DNAPTP6\": {\n \"rs12612420\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"LEPR\": {\n \"rs12405556\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"RN7SK–SLC44A1\": {\n \"rs7858499\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"C18orf2\": {\n \"rs8097348\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"GABRG3\": {\n \"rs8036270\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Habitual Physical Activity\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE \",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE \",\n \"result_description\": \"Your result is correlated with a intermediate likelihood of frequent, vigorous, habitual physical activity.\",\n \"risk_management\": \"You should strive to exercise at least 2 to 3 times per week. Group activities and sports can help improve your chances of getting a sufficient amount of exercise. A personal trainer can also help give you guidance and accountability, making you more likely to remain healthy.\",\n \"actionable_trait\": \"No\",\n \"recommendations\": [],\n \"star_rating\": 3,\n \"snp_table_caption\": \"The genes below are correlated with your likelihood of developing consistent exercise habits on a weekly basis.\",\n \"about\": \"Physical activity protects against a wide range of diseases.\\n\\nHabitual physical activities are those that are performed on a regular basis, without having to \\\"force\\\" yourself into the gym. It includes exercise as well as passive activities, such as recreational sports or simply walking or biking to work. A sedentary lifestyle increases the risk for cardiovascular disorders and obesity, as well as diabetes, stroke, metabolic syndrome, and more. If you aren't naturally inclined to exercise frequently, take time to create a healthy schedule and do your best to stick with it.\",\n \"caption\": \"How Often You Naturally Exercise\",\n \"refreances\": [\n \"1.\\tKlimentidis, Y. C., Raichlen, D. A., Bea, J., Garcia, D. O., Wineinger, N. E., Mandarino, L. J., Alexander, G. E., Chen, Z., & Going, S. B. (2018). Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE. International Journal of Obesity, 42(6), 1161–1176. https://doi.org/10.1038/s41366-018-0120-3\"\n ],\n \"GENES\": {\n \"HIST1H1D\": {\n \"rs10946808\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"CTC-436P18.1\": {\n \"rs159543\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"CADM2\": {\n \"rs4301023\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"DPY19L1\": {\n \"rs328902\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n }\n }\n }\n }\n}"},{"id":"7f3c7c98-2265-4fe5-b70d-5ff3dceeffef","name":"Fitness Report Customer With No DNA File Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1c2b7b12b289_709f9fd16bb5_8aafce768660\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/fitness/report"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; 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Description: This Endpoint generates/retrieves the latest health and wellness report for any customer

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String

Response Parameters:

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Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

report_json

JSON

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You may use Nicotine Replacement Therapy (NRT) with products like patches, inhalers, or quitting medications as recommended by your physician to manage withdrawal symptoms. Eating a balanced diet and a variety of fruits and vegetables regularly is needed to better support your health while smoking. Daily supplementation with antioxidants, like Vitamins C, is required to help reduce the effects of free radicals, chemicals that trigger cancer development.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Early detection of nicotine dependence provides information on the predisposition of an individual to smoking addiction. Such information can help encourage you to avoid cigarettes, as well as to identify the rate of an individual's withdrawal reaction to quitting.\",\n \"about\": \"Smoking behavior and nicotine dependence are risk factors of many diseases, one of which is the onset of lung cancer. It also damages your heart and blood vessels, and increasing your risk of heart disease and stroke. It causes high blood pressure, lowers your ability to exercise, and makes blood more likely to clot. \\n\\nCertain genetic variants are associated with smoking initiation, quantity, and smoking cessation (quitting). While environmental factors like exposure and social norms affect your smoking behavior, your genetic profile for a smoking habit can help you gain control and manage the risks. \",\n \"caption\": \"How you respond to smoking and nicotine.\",\n \"GENES\": {\n \"CHRNA3\": {\n \"rs1051730\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"HECTD2-AS1\": {\n \"rs4933206\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"SMIM19\": {\n \"rs6474412\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"EGLN2\": {\n \"rs3733829\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"BDNF\": {\n \"rs6265\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"DNMT3B\": {\n \"rs2424928\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Alcohol Consumption\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"High Likelihood\",\n \"result_description\": \"You have a higher propensity for increased alcohol consumption based on your genetic result, predisposing you to a high risk of alcohol dependence, abuse, and addiction, or alcohol use disorder (AUD). However, social norms and environmental influences may modify the likelihood.\",\n \"risk_management\": \"With increased alcohol volume intake, you may have long-term acute damage to your organs, like the liver, pancreas, and brain, which also increases with alcohol use disorder (AUD). A combination of Vitamin C and Silymarin supplementation supports a reduction in reactive oxygen species (ROS) that damages your cells during alcohol-induced lesions to organs. Abstinence or drinking in moderation is highly recommended. \\n\\nTo identify your own risks, use Phosphatidylethanol (PEth) Testing / Alcohol Use Disorders Identification Test\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Knowing your genetic risk for alcoholic health damage can help inform smarter levels of consumption. It also provides information on tolerance and how much you can recover from a severe glutamine rebound after the complete metabolism of alcohol.\",\n \"about\": \"Alcohol consumption is a risk factor for many diseases. It is a component cause of more than 200 other diseases and health conditions. However, for these conditions, alcohol follows a dose-response relationship for the risk of death or disease, so the risk associated with alcohol consumption is largely modifiable through a healthy lifestyle. \\n\\nCertain people tolerate alcohol's effects poorly and have a higher tendency towards alcoholism; therefore, they are at risk for long-term damage to organs, including the liver and pancreas.\",\n \"caption\": \"Alcohol is never safe, no matter your genes.\",\n \"GENES\": {\n \"GCKR\": {\n \"rs1260326\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"KLB\": {\n \"rs11940694\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"CADM2\": {\n \"rs1375547\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"Intron, PECR-MREG\": {\n \"rs7590720\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Insomnia\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"High Likelihood\",\n \"result_description\": \"You have a high risk of being an insomniac. Detrimental habits, like maintaining an irregular sleep schedule or working in bed, may disrupt your sleep rhythms. \",\n \"risk_management\": \"Being in a low-stress environment and being physically active can help prevent insomnia and normalize your sleep patterns in the long run. Make sure to stick to a regular sleep schedule, whether it's a weekday or the weekend. Regularly exercising for at least 30 minutes per day (for most days of the week) can also help condition your mind and body. \\n\\nGet ample natural light exposure during the day (at least 10-15 minutes), and take a warm bath or shower before bed. In extreme cases, cognitive behavioral therapy from a healthcare professional would benefit you better in order to prevent drug dependence and tolerance. \\n\\nDiagnostic Test:\\nOvernight sleep study\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Discovering your risk of becoming an insomniac allows for early treatment. Insomnia is a chronic disease that requires long-term medication and treatment; earlier detection allows faster treatment and customized strategies. A change in lifestyle habits may be sufficient to improve your sleep.\",\n \"about\": \"Insomnia is a sleep disorder that is characterized by difficulty falling asleep or staying asleep. People with insomnia have one or more of the following symptoms: difficulty falling asleep; waking up often during the night; having trouble going back to sleep.\",\n \"caption\": \"Staying awake or waking up often at night.\",\n \"GENES\": {\n \"CYCL1\": {\n \"rs7060133\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Appendicitis\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"Based on your results, you carry an intermediate risk of developing appendicitis. However, if exposed to risk factors, appendicitis may be triggered.\",\n \"risk_management\": \"There is no absolute prevention, but appendicitis is less common in people who have high-fiber diets with fruits and vegetables. Eating the seeds of fruits and vegetables is one of the causes of acute appendicitis, due to the obstruction of the appendix lumen; other blockages may also occur from stool, foreign bodies, tumors, or infections. If your abdomen becomes painful, you should have it checked immediately. In extreme cases, emergency surgery is required to prevent rupture.\\n\\nDiagnostic Test:\\nPhysical examination with blood, urine, and imaging.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Appendicitis is a severe condition that can result in multiple complications. Take preventive measures to reduce your risk.\",\n \"about\": \"Appendicitis is the inflammation of the appendix, a finger-shaped pouch that projects from your colon on the lower right side of your abdomen. While the appendix doesn't serve critical functions, an appendix can rupture as quickly as 48 to 72 hours after the onset of symptoms, which may be potentially lethal. Knowing your risk can help you prepare in advance.\",\n \"caption\": \"Potentially serious and often unnoticed.\",\n \"GENES\": {\n \"PITX2\": {\n \"rs11931959\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Attractiveness to Mosquitoes\": {\n \"result_options\": [\n \"Low likelihood\",\n \"Intermediate Likelihood\",\n \"High likelihood\"\n ],\n \"result\": \"Low likelihood\",\n \"result_description\": \"Based on your genes, you have a low likelihood of being attractive to mosquitoes. However, other non-genetic factors that would naturally make you detected by mosquitoes are CO2 dissipation from your body and your body heat. \",\n \"risk_management\": \"The use of repellents and anti-mosquito lotions can help when going into mosquito-prevalent sites. If no repelent is available, be sure to wear clothes that cover as much skin area as possible. Use mosquito net when sleeping outdoors (e.g. during camping). Avoid blue-to-black or pink-to-red colored clothes because studies show that mosquitoes have a significant visual preference to these colors.\\n\\nDiagnostic Test\\nOlfactometer Test\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Mosquitoes carry many diseases, so your attractiveness to mosquitoes is a serious health risk. This DNA test also identifies individuals who may be allergic to mosquito bites.\",\n \"about\": \"Depending on your DNA, you may be more attractive to mosquitoes. Their bite size and itch intensity also varies if mosquitoes are particularly drawn to you; some people have more intense reactions to mosquito bites than others.\",\n \"caption\": \"Sometimes, being attractive isn't so great.\",\n \"GENES\": {\n \"BC045668-CETN4P\": {\n \"rs309414\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"HLA-DRA\": {\n \"rs8084\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Inguinal Hernia\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"High Likelihood\",\n \"result_description\": \"You are more likely to develop an inguinal hernia than the general population. \",\n \"risk_management\": \"Prevention strategies include maintaining an ideal body weight by eating a healthy diet and exercising. Meals should frequently include fruits, vegetables, and whole grains to avoid constipation, and you should avoid processed and fatty foods. If you go to the gym, make sure to practice correct form when lifting weights, or when lifting heavy objects elsewhere. Smoking and coughing can trigger hernia development. In extreme cases, surgery may be needed to repair it.\\n\\nDiagnostic Test\\nPhysical Check-Up\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Inguinal hernia is more frequently observed in men than women; older people are also more susceptible because of weakened abdominal muscles due to aging. In women, pregnancy can cause weakness in the abdominal walls, which can cause the condition. \\n\\nA previous inguinal hernia removed via surgery also indicates a risk of further hernia development.\",\n \"about\": \"An inguinal hernia occurs when tissue, such as part of the intestine, protrudes through a weak spot in the abdominal muscles. The resulting bulge can be painful, especially when you cough, bend over, or lift a heavy object. \\n\\nHernias don't disappear on their own; they can grow larger and more painful, then develop into complications. Therefore, it's important to identify people with this risk and manage their lifestyle. \",\n \"caption\": \"Painful, potentially dangerous rupture in the abdominal wall.\",\n \"GENES\": {\n \"EFEMP1\": {\n \"rs2009262\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"EBF2\": {\n \"rs6991952\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Motion Sickness (car sickness) \": {\n \"result_options\": [\n \"Low likelihood\",\n \"Intermediate Likelihood\",\n \"High likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"You result is associated with an intermediate likelihood of having motion sickness. However, environmental exposures and lifestyle may modify this likelihood. \",\n \"risk_management\": \"If you want to avoid motion sickness, drinking ginger tea can help you. Other behavioral strategies may help, like watching the true visual horizon, steering the vehicle (rather than being a passenger), tilting your head into turns, or lying down with your eyes closed. If you prefer anti-motion sickness medications, Scopolamine patches, administered several hours before travelling, can help. When travelling, you should position yourself in the most stable part of the vehicle, like the front seat in a car. First-generation antihistamines that are sedating are also effective in motion sickness management. However, with constant travels, most people will adapt.\\n\\nMotion sickness susceptibility can be tested from two successive exposures to each of three tests: 1) Coriolis Sickness Sensitivity Index (CSSI); 2) Staircase Velocity Movement Test (SVMT); and 3) Parabolic Flight Static Chair Test (PSCT).\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Knowing your predisposition to motion sickness can allow you to take precaution during travel; it is also suggested that you take an antivertigo to relieve the discomfort of the condition.\",\n \"about\": \"Motion sickness is a common problem in people traveling by car, train, airplane, and especially by boat. It is a common syndrome occurring upon exposure to certain types of motion, and is believed to be caused by a conflict in proprioceptive systems (the perception of the position and movement of the body). Nausea is a hallmark symptom, preceded by malaise, drowsiness, and irritability. \",\n \"caption\": \"Find the most stable part of the car to reduce symptoms.\",\n \"GENES\": {\n \"LOC105374035, LOC105374036\": {\n \"rs66800491\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"GPD2\": {\n \"rs56051278\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"ACO1\": {\n \"rs10970305\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n },\n \"AUTS2\": {\n \"rs1195218\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"GPR26\": {\n \"rs705145\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"CBLN4\": {\n \"rs11696973\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"MUTED\": {\n \"rs2153535\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"LINGO2\": {\n \"rs2150864\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"CPNE4\": {\n \"rs9834560\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Resting heart rate, RHR\": {\n \"result_options\": [\n \"Low likelihood\",\n \"Intermediate Likelihood\",\n \"High likelihood\"\n ],\n \"result\": \"High likelihood\",\n \"result_description\": \"You are more likely to have an increased resting heart rate, which is associated with increased cardiovascular disease and a higher mortality risk. \",\n \"risk_management\": \"Lowering an elevated resting heart rate is known to be protective against all-cause and cardiovascular-related mortality. Normalizing an elevated resting heart rate is known to reduce your risk of death.\\n\\nThe World Health Organization (WHO) recommends at least 150 minutes of moderate-intensity aerobic activity throughout the week, or at least 75 minutes of vigorous aerobic activity throughout the week to reduce these risks. Reduction of stress and performing relaxation, meditation, and tai chi exercises gradually slows down your resting heart rate. Avoiding or quitting tobacco products brings resting heart rate down. Lastly, obesity is a major risk factor contributing to increased resting heart rate because a larger body requires more work to supply blood to the whole system; losing weight will normalize an elevated resting heart rate. \\n\\nDiagnostic Test:\\nPulse check, Blood pressure monitor/ Sphygmomanometer\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Having a high resting heart rate is associated with high blood pressure, which can lead to multiple chronic and acute health problems. Identifying your risk can offer advice on lifestyle changes, such as the proper diet and exercise routine.\",\n \"about\": \"A higher resting heart rate is associated with an increased risk of cardiovascular disease, cardiovascular mortality (including sudden death), and all-cause mortality, independent of other risk factors. A normal resting heart rate for adults ranges from 60 to 100 beats per minute. \\n\\nGenerally, a lower heart rate at rest implies more efficient heart function and better cardiovascular fitness. For example, a well-trained athlete might have a normal resting heart rate closer to 40 beats per minute. High heart rates may promote the development of atherosclerosis and plaque ruptures through increases in cardiac work, decreased arterial compliance, and increases in arterial wall stress. Genes influence resting heart rate, and aging speeds up the heart. Regular exercise slows down heart rates to normal levels.\",\n \"caption\": \"Your heart - on the couch.\",\n \"GENES\": {\n \"Intergenic, 400 kb from GJA1\": {\n \"rs9398652\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"MYH6\": {\n \"rs452036\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"MYH6@DUB422\": {\n \"rs365990\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"UfSp1\": {\n \"rs314370\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"Intergenic\": {\n \"rs17287293\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Inflammatory response\": {\n \"result_options\": [\n \"Lower response\",\n \"Intermediate response\",\n \"Higher response\"\n ],\n \"result\": \"Intermediate response\",\n \"result_description\": \"Your result is correlated with an intermediate inflammatory response.\",\n \"risk_management\": \"Your risk of inflammatory disease is not elevated, but if you do have existing inflammatory problems, such as rheumatoid arthritis or asthma, you can reduce adverse reactions by avoiding red meats such as pork, beef, and veal, as well as food allergens, such as poultry and poultry products in your diet. If you do not have such inflammatory problems, a well-balanced, nutritionally optimized diet should work for you. \\n\\nInflammation in the body can be detected by measuring Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and plasma viscosity (PV) blood tests. Elevated values of these tests can be indicative of inflammation.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Without inflammation as a physiological response, wounds would fester, and infections could become deadly. However, if the inflammatory process goes on for too long or if the inflammatory response occurs in places where it is not needed, it can become problematic and may lead to disease.\",\n \"about\": \"The inflammatory response, or inflammation, can be good or bad depending on the situation. It's your body's natural way of protecting itself when you're injured or sick. It can help your body defend itself from illnesses and stimulate healing. On the other hand, chronic, sustained inflammation in your body is linked to an increased risk of diseases like diabetes, heart disease, and obesity. Interestingly, the food you eat can have a major effect on inflammation in your body.\",\n \"caption\": \"Your body's natural inflammatory response.\",\n \"GENES\": {\n \"TNF/LTA\": {\n \"rs1800629\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"IL10\": {\n \"rs1800896\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"FCRL3\": {\n \"rs7528684\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Cannabis Dependence & Mental Health \": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Low Likelihood\",\n \"result_description\": \"Based on your genetics, your likelihood of cannabis dependence is low. However, environmental factors, like social norms and peers, may influence your behavior and can increase the likelihood. \",\n \"risk_management\": \"Your physician may recommend CBD oil for the treatment of chronic pain, insomnia, depression, and anxiety, since cannabidiol (CBD) oil may work as a safer substitute for marijuana because it is non-psychoactive, while marijuana contains high quantities of Tetrahydrocannabinol (THC) which causes hallucinations and mental health risks.\\n\\nDiagnostic Test:\\nUrine testing, blood testing, hair analysis, and saliva testing for cannabinoids\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Cannabis is highly addictive due to its regulation of the hormone dopamine that stimulates brain areas; being aware of your predisposition to cannabis dependence allows for dosing adjustments when used medically.\",\n \"about\": \"Cannabis use is more likely in people with certain personality traits, especially optimism and a carefree attitude. However, personality is not an absolute predictor of cannabis use, and legalization may change this relationship, as it may require less of a carefree nature to use a drug that is legal.\",\n \"caption\": \"Marijuana and cannabis products.\",\n \"GENES\": {\n \"CADM2\": {\n \"rs4301023\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"ZNF704\": {\n \"rs7018449 \": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"SMG6\": {\n \"rs17761864\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n },\n \"CADM2@DUB826\": {\n \"rs1375547\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Sleep Duration \": {\n \"result_options\": [\n \"Low likelihood\",\n \"Intermediate Likelihood\",\n \"High likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"You have a normal likelihood of getting 7-8 hours of sleep every night. \",\n \"risk_management\": \"You are inclined to get an average amount of sleep, but even occasional nights of sleeplessness can put you at risk for coronary heart diseases and/or diabetes mellitus. Limiting your exposure to artificial light at the end of the day can help improve your sleep quality and duration. Plenty of regular exercise can also help manage your sleep cycles.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Being aware of your genetic sleep inclinations can help you create a healthier sleep schedule and lifestyle.\",\n \"about\": \"Sleep duration varies across ages. Adults generally need around 7- 8 hours of shut-eye every night. Not meeting these numbers can lead to chronic diseases, such as coronary heart disease and diabetes mellitus. It is important to know your genetic predisposition for sleep duration in order to take measures to correct your sleeping hours.\",\n \"caption\": \"Sleep is critical to your mental and physical health - every single night.\",\n \"GENES\": {\n \"PAX8\": {\n \"rs62158211\": {\n \"genotype\": \"TG\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Job related exhaustion\": {\n \"result_options\": [\n \"Low likelihood\",\n \"Intermediate Likelihood\",\n \"High likelihood\"\n ],\n \"result\": \"Low likelihood\",\n \"result_description\": \"You have a low likelihood of suffering from job-related exhaustion. However, fatigue is possible for anyone. \",\n \"risk_management\": \"Even if you have lower risk of experiencing Job-related exhaustion, you should still exercise in caution. Fatigue can result from a combination of job demands, physical load, coworker relationships, long work hours, the disruption of circadian rhythms, mental load, and cumulative sleep debt. Sleep recovery is required for the effective management of workplace fatigue. \\n\\nUsing the Fatigue Risk Management System (FRMS) can help. The first step is the minimization of sleep loss, adhering to the minimum recommended 8 hours of sleep. Fatigue risk increases exponentially for people working 12-hour shifts or starting work early. \\n\\nEat healthy meals after a tiring day of work. Quick forms of exercise can also boost your mood and give you energy to go through the day.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Early detection of the predisposition to job-related exhaustion can help develop effective coping mechanisms and avoid health risks associated with excessive burnout.\",\n \"about\": \"Job-related exhaustion is simply work-related burnout. Some people tend to fatigue more during work than others. A recent study has linked this trait and a certain genetic variant with an increased risk of Alzheimer's. Worker's fatigue is a significant problem in modern businesses. \",\n \"caption\": \"How quickly you get tired at work.\",\n \"GENES\": {\n \"MTNR1A\": {\n \"rs12506228\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"DNA Damage and Detoxification Ability \": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"High Likelihood\",\n \"result_description\": \"Your result is associated with a high risk of DNA damage caused by cooked meat, indicating low detoxification ability. \",\n \"risk_management\": \"The heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons (PAHs) are mutagenic chemicals formed when muscle meat, including beef, pork, fish, or poultry, is cooked using high-temperature methods, such as pan-frying or grilling directly over an open flame. \\n\\nThese chemicals are detoxified by the genes in this test and your result is associated with a low detoxification ability. Limit your intake of meats cooked at high temperatures to 1-2 servings per week. Regular Vitamin C intake from supplements or citrus fruits can help support detoxification. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Meats generate cancer-causing chemicals (\\\"carcinogens\\\") when exposed to high temperatures.\\n\\nThese genes affect your body's ability to detoxify or eliminate those carcinogens. They may also affect how much of those cancer-causing substances are released in your body after consuming meat.\\n\\nEven with improved detoxification, it's important to monitor and limit your consumption of meat, especially smoked or processed meats, which have the highest levels of carcinogens. \",\n \"about\": \"Detoxification is a process that the body performs around the clock, using important nutrients from the diet. It's the process that transforms toxins so they can be removed from the body. They fall into two main categories: toxins that are made in the body during regular metabolism, and those that come from outside the body and are introduced by eating, drinking, breathing, or absorbed through the skin.\\n\\nToxins that are produced in the body include lactic acid, urea, and waste products from microbes in the gut. External toxins may include pesticides, mercury in seafood, lead from car exhaust and air pollution, chemicals in tobacco products, and drugs or alcohol.\",\n \"caption\": \"Your body's natural detox ability.\",\n \"GENES\": {\n \"CYP1A2\": {\n \"rs762551\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n },\n \"EPHX1\": {\n \"rs1051740\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"AHR\": {\n \"rs2066853\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Excessive Sweating (Hyperhidrosis)\": {\n \"result_options\": [\n \"Low likelihood\",\n \"Intermediate Likelihood\",\n \"High likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"You have an intermediate likelihood of developing excessive sweating or hyperhidrosis. \",\n \"risk_management\": \"If sweating tendencies are aggravated, there are several treatment options, including topical aluminum chloride hexahydrate 20% for 3 to 4 nights, then nightly as needed. If a topical aluminum chloride treatment doesn't work, oral anticholinergic medications (Oxybutynin 5-10 mg per day or topical glycopyrrolate 0.5-2%) to block the cholinergic receptors are used, as recommended by physicians. For advanced cases that are resistant to these conservative therapies, you may be recommended botulinum toxin A injections every 3 to 4 weeks. Last resort options include sympathectomy (removal of at least one sympathetic ganglion) or local excisions. \",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Hyperhidrosis is related to frequent heat rashes; knowing your predisposition allows you to take precautions, such as dermatological consultations, and other preventive measures.\",\n \"about\": \"Sweating plays an important role in regulating body temperature and is performed by eccrine and apocrine sweat glands in the skin. Hyperhidrosis, or excessive sweating, can be caused by various pathologies, and the presence of increased sweating can lead to embarrassment in social situations and sometimes impairs quality of life. \\n\\nStudies have identified other autonomic nervous system abnormalities in people with hyperhidrosis, such as differences in cardiovascular stress responses, that point to an over-functioning of sympathetic and possibly parasympathetic nervous system fibers.\",\n \"caption\": \"Staying cool - or sweating too much.\",\n \"GENES\": {\n \"ABCC11\": {\n \"rs17822931\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"Intronic\": {\n \"rs7586405\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Alcohol Response\": {\n \"result_options\": [\n \"Lower response\",\n \"Normal response\",\n \"Higher response\"\n ],\n \"result\": \"Higher response\",\n \"result_description\": \"According to your genetic test, your result is associated with high response to alcohol, indicating that your body can quickly metabolize alcohol compared to others.\",\n \"risk_management\": \"Quickly metabolizing alcohol may lower your risk of a hangover, but other issues may arise as a result, including alcohol dependence. With a higher likelihood of fast alcohol metabolism, you may have a higher threshold level for the buildup of acetaldehyde in your liver, and your blood alcohol accumulation is slower, causing slower intoxication. \\n\\nAn average person can metabolize one serving of alcohol (12 oz beer, 5 oz table wine, or 1.5 oz hard liquor) in 1 hour, but your limit per hour can be higher than this. \",\n \"star_rating\": 2,\n \"snp_table_caption\": \"The ALDH gene can cause greater hangovers and negative responses to alcohol.\\n\\nThis gives us an idea of how your body responds to alcohol. However, even if you have a \\\"good\\\" response to alcohol, this drug can still cause cancer and liver disease, so limiting or completely eliminating your alcohol intake is always recommended.\\n\\nAlcohol dehydrogenase (an enzyme in your body) converts ethanol to acetaldehyde that is subsequently metabolized to acetate by Aldehyde dehydrogenase (ALDH).\",\n \"about\": \"There is no genetic predisposition that makes alcohol safe. Any amount of alcohol can lead to serious health issues, including cancer and liver damage.\\n\\nIf you have genes that make drinking more enjoyable, you may want to take conscious steps to avoid it; since your body doesn't feel the negative effects as easily, you may be inclined to drink more than you should. For everyone, the recommendation is to drink as little alcohol as possible.\\n\\nWhile some people suggest that alcohol has benefits to your heart health, the truth is that those benefits are minor in comparison to the risks, and the same heart health benefits can be gained from non-alcoholic foods and drinks.\",\n \"caption\": \"Your body's alcohol response.\",\n \"GENES\": {\n \"ALDH2\": {\n \"rs671\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Alcohol Addiction\": {\n \"result_options\": [\n \"Low likelihood\",\n \"Intermediate Likelihood\",\n \"High likelihood\"\n ],\n \"result\": \"Low likelihood\",\n \"result_description\": \"Your results are associated with a low likelihood of developing alcohol dependence. \",\n \"risk_management\": \"For your overall health, it is best to avoid alcohol entirely or limit it to occasional social engagements. However, environmental factors, lifestyle, stress, and social norms can modify this likelihood. Continuous or habitual drinking increases the risk of alcoholism. \\n\\nWhile all alcohol can cause intoxication, beer can cause unwanted fat gain due to its calories, and red wine can be beneficial for heart health when drunk in moderation.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"There are different genes involved in your natural cravings for alcohol. While anyone can develop alcohol dependence from excessive drinking, your genetic markers can warn you of an increased risk for alcohol abuse.\",\n \"about\": \"Alcohol dependence isn't limited to people who lose their jobs and families because of drinking. The social acceptability of drinking can make alcohol dependence seem unproblematic or even invisible.\\n\\nDeveloping a high tolerance for alcohol, being preoccupied with your next drink, or simply consuming alcohol on a daily basis can all mean alcohol dependence. \\n\\nThere is no safe amount of alcohol. Even though there may be some heart health benefits associated with the ingredients in some alcoholic beverages, the risk for cancer and other illnesses will always outweigh the benefits. \\n\\nLowering your alcohol consumption will help you rehydrate your body, refresh your mind, and keep your whole system healthy.\",\n \"caption\": \"Avoid damage to the liver, brain, and other organs.\",\n \"GENES\": {\n \"HECTD4\": {\n \"rs2074356\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"CCDC63\": {\n \"rs10849915\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"AUTS2\": {\n \"rs10234844\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"ADH1B\": {\n \"rs1229984\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Longevity\": {\n \"result_options\": [\n \"Low likelihood\",\n \"Intermediate Likelihood\",\n \"High likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"Your genetic profile for longevity is correlated with a normal lifespan. However, detrimental habits like smoking, alcoholism, fatty and processed food intake, and exposure to hazardous chemicals and pollutants will take a toll on your body.\",\n \"risk_management\": \"To maximize longevity and life expectancy, live a healthy lifestyle with balanced levels of carbohydrates, fats, proteins, vitamins, and minerals. \\n\\nAvoid smoking, drinking, and using drugs. A healthy weekly exercise routine includes at least 150 minutes of moderate aerobic activity (or 75 minutes of vigorous aerobic activity), as recommended by the World Health Organization (WHO). Exercise will improve cardiorespiratory health, muscular fitness, and bone health, while reducing the risk of non-communicable diseases and lowering rates of depression. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Although longevity is not solely based on your genetics, this report helps you to know your chances of having a full long life of more than 100 years.\",\n \"about\": \"Longevity is the length of one's lifespan. Some genetic markers correlate to a longer lifespan. This test, when reversed, is not reflective of mortality; in other words, you are not more likely to pass away at a young age if you don't have the genes for longevity.\",\n \"caption\": \"Your chance of living to 100.\",\n \"GENES\": {\n \"APOC1\": {\n \"rs4420638\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"TOMM40\": {\n \"rs2075650\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"IL6\": {\n \"rs2069837\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"LOC101927697\": {\n \"rs2149954\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Male Pattern Baldness (man)\": {\n \"result_options\": [\n \"Low likelihood\",\n \"Intermediate Likelihood\",\n \"High likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"Your genetic result is associated with an intermediate likelihood of developing male pattern baldness. However, this can be triggered by stressful life events, poor health, or anxiety. \",\n \"risk_management\": \"Effective stress management through frequent meditation, exercise, relaxation, sleep, social connections, balanced nutrition, and task prioritization can help prevent its onset. When hair loss happens, there are two treatments widely available in the market: 1 mg Finasteride tablets and 5% Minoxidil topical spray. Finasteride is available for prescription only, while 5% Minoxidil is available over the counter. Low-level laser light therapy offered by professional doctors is also an effective treatment method. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Early intervention can help maximize the amount of hair saved. Once the hair follicle is gone, it cannot be regrown. \",\n \"about\": \"Male pattern hair loss (also known as androgenic alopecia, or \\\"AGA\\\") affects all men to some degree as they grow older. Progressive thinning of the hair on the head eventually leads to baldness. However, there are some people who are predisposed to a faster progression of alopecia. It occurs with varying severity and at different stages in life. AGA can affect up to 50% of males between the ages of 30 and 50.\",\n \"caption\": \"Classic hair-loss pattern.\",\n \"GENES\": {\n \"AR\": {\n \"rs2497938\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"PAX1, FOXA2\": {\n \"rs6047844\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"LINC01432, RPL41P1\": {\n \"rs2180439\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"HDAC4\": {\n \"rs9287638\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HDAC9\": {\n \"rs2073963\": {\n \"genotype\": \"GT\",\n \"effect_allels\": 1\n }\n },\n \"TARDBP\": {\n \"rs12565727\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"Intergenic\": {\n \"rs12185268\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"AUTS2\": {\n \"rs6945541\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"SETBP1\": {\n \"rs10502861\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Kidney Stone Predisposition\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"Based on your genetics, you have an intermediate risk of developing kidney stones. \",\n \"risk_management\": \"It is recommended that you avoid or take in only moderate amounts of kidney stone-forming foods, such as beef and soda. Preventive strategies involve dietary intervention. Plenty of water or fluid is needed; during the onset of kidney stones, you need to achieve a daily urine output of 2 liters. Avoiding oxalate stone-forming foods is highly advised: avoid beef, chocolate, rhubarb, beets, spinach, nuts, wheat bran, soy, strawberries, and soda. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Knowing your genetic predisposition to kidney-stone formation will help you avoid certain foods and habits that will aggravate your risk. \",\n \"about\": \"A kidney stone is a hard, crystalline mineral formed within the kidney or urinary tract. Kidney stones are a common cause of blood in the urine (hematuria) and often cause severe pain in the abdomen, side, or groin. It is associated with an increased risk of end-stage renal failure.\",\n \"caption\": \"Painful and potentially dangerous kidney stones.\",\n \"GENES\": {\n \"AQP1\": {\n \"rs1000597\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"DGKH\": {\n \"rs4142110\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"RGS14\": {\n \"rs11746443\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"KCNK5\": {\n \"rs1544935\": {\n \"genotype\": \"GT\",\n \"effect_allels\": 1\n }\n },\n \"DGKH@DUB938\": {\n \"rs4598803\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"PDILT\": {\n \"rs11864909\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"LOC645722\": {\n \"rs7215775\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n }\n }\n }\n }\n}"},{"id":"97898e12-e057-4054-8427-67bd28fef7ee","name":"Health And Wellness Report Customer With No DNA Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1c2b7b12b289_709f9fd16bb5_8aafce768660\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/hw/report"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"6748ba91ba72ca3c562e2122fdb84a72\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"9df4b2f9-e60a-47f0-b6ec-b5d98cf19ed4"},{"key":"X-Runtime","value":"0.011957"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Customer DNA File Not Found\"\n}"}],"_postman_id":"17046530-33af-4bb1-a97a-e48d18276a84"},{"name":"Personality And Cognition Report","id":"d1ad473a-54e2-4953-932a-6ccd6686fa19","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/pc/report","description":"

Description: This Endpoint generates/retrieves the latest personality and cognition report for any customer

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People with a high level of agreeableness are associated with good leadership skills, social interactions, and a persuasive nature. People with a low level of this trait, however, tend to take little or no interest in others: they don't care about the feelings of the people around them. People with low levels of agreeableness also tend to be manipulative in order to get what they want. Agreeableness is also linked to a higher likelihood of being a morning person. This trait is more common in older people.\",\n \"caption\": \"How kind, warm, and empathetic you tend to be.\",\n \"GENES\": {\n \"CLOCK\": {\n \"rs6832769\": {\n \"genotype\": \"GA\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"THUMPD2\": {\n \"rs2540226\": {\n \"genotype\": \"AC\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"OXTR \": {\n \"rs53576\": {\n \"genotype\": \"GA\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"OXTR @DUB212\": {\n \"rs2268491\": {\n \"genotype\": \"CC\",\n \"text\": \"High likelihood\"\n }\n },\n \"CHRNB3\": {\n \"rs4950\": {\n \"genotype\": \"AG\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Conscientiousness\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Low Likelihood\",\n \"result_description\": \"You have a low likelihood of task completion and self-discipline. Your propensity may incline you towards being more easy-going and disorderly. You tend to dislike structure and schedules. People with this SNP are also likely to be messy. You are probably prone to procrastination. Environment, upbringing, and lifestyle may influence your personality, and you can always strive to become more structured and organized if you choose.\",\n \"risk_management\": \"Self-discipline, organization, and good scheduling habits are not determined entirely by your genetics. You can always practice new skills and improve your chances of success. \\n\\nDiagnostic Test\\nMyer Briggs Personality Test\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Conscientiousness people are methodical, but that doesn't make them cold: they may be more aware of team dynamics and better able to create a friendly working environment. \",\n \"about\": \"Conscientious people tend to be thoughtful, with good impulse control, and are goal-oriented. Their methodical planning and perseverance usually make them highly successful. \",\n \"caption\": \"Impulse control and a goal-oriented nature.\",\n \"GENES\": {\n \"KATNAL2\": {\n \"rs2576037\": {\n \"genotype\": \"TT\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Openness\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Low Likelihood\",\n \"result_description\": \"You have a low likelihood of \\\"going out of your comfort zone\\\"; consistent routines and conventional methods may work well for you. Intentionally exposing yourself to new experiences is an important part of improving and expanding your mind.\",\n \"risk_management\": \"New experiences can have a positive effect on emotional wellbeing and intelligence, even if you aren't naturally inclined to seek them out. Consider trying something new this week, even if that simply means a new genre of books, a new hobby, or a type of exercise you haven't tried before.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Openness feeds an individual's curiosity and allows them to take on new challenges with a positive mindset.\",\n \"about\": \"Openness is one of the ‘Big Five’ dimensions of personality. People with high levels of openness tend to love learning new things and enjoy new experiences. This trait is associated with creativity and adventurousness. Openness is also the only personality trait associated with intelligence: new experiences tend to grow the brain and offer new sources of inspiration and challenges.\",\n \"caption\": \"Do new experiences invigorate you?\",\n \"GENES\": {\n \"RASA1\": {\n \"rs2032794\": {\n \"genotype\": \"TT\",\n \"text\": \"Low likelihood\"\n }\n },\n \"ERBB4\": {\n \"rs1879637\": {\n \"genotype\": \"CT\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Extraversion\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"You have a genetic inclination between introversion or extraversion. Your personal experiences may have a greater impact on you than your genes in this particular case.\",\n \"risk_management\": \"There is no \\\"risk management\\\" for this trait because both introverts and extraverts can lead fulfilling and successful lives. Finding a lifestyle that works for you and fulfills you is more important than trying to change this trait.\\n\\nDiagnostic Test\\nMyer Briggs Personality Test\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Extraverted people draw energy from socialization and connecting with other people. Extraverted people may feel drained if they spend too much time alone or in low-excitement environments.\",\n \"about\": \"Extraversion is characterized by excitability, sociability, talkativeness, assertiveness, and high emotional expressiveness. A person who scores high in extraversion on a personality test is often the life of the party. They enjoy being with people and participating in social gatherings, and they are often full of energy. A person low in extraversion is less outgoing and is typically more comfortable working alone.\\n\\nWhile often spelled 'extroversion,' Carl Jung, the creator of the term, wrote it with an 'a' because of its Latin roots.\",\n \"caption\": \"Tendency to seek out excitement.\",\n \"GENES\": {\n \"WSCD2 (Intron)\": {\n \"rs3764002\": {\n \"genotype\": \"CC\",\n \"text\": \"High likelihood\"\n }\n },\n \"MTMR9 (intron)\": {\n \"rs3808518\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Neuroticism\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"High Likelihood\",\n \"result_description\": \"You have a higher likelihood of being moody and experiencing feelings such as anxiety, worry, fear, anger, frustration, envy, jealousy, guilt, depression, and loneliness. Individuals in this group may harbor uncomfortable negative emotional reactions to minor challenges and significant difficulties. \",\n \"risk_management\": \"A genetic risk for neuroticism can be mitigated by establishing strong social support systems with family, friends, or loved ones, as well as being involved in fun recreational activities. A lifestyle or job that is demanding and stressful may further contribute to your risk of neuroticism. Creating the opportunity for relaxation and stress-relief is important. Meditation can also be incredibly helpful for you.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Neuroticism is highly linked with the incidence of mental health issues. This genetic trait can help you and your doctor identify the early warning signs of anxiety and determine a helpful treatment or preventative plan.\",\n \"about\": \"Neuroticism is one of the Big Five personality traits. It is a long-term and relatively stable tendency to be in a negative or anxious emotional state, especially in response to threats, frustration, or loss. Individuals who score high in this trait tend to experience mood swings, anxiety, irritability, and sadness. Neuroticism can also be damaging to the quality of your life and reduce your lifespan. \",\n \"caption\": \"Anxiety, frustration, and fear.\",\n \"GENES\": {\n \"PTRD\": {\n \"rs12378446\": {\n \"genotype\": \"TT\",\n \"text\": \"High likelihood\"\n }\n }\n }\n },\n \"Depression\": {\n \"result_options\": [\n \"Low Risk\",\n \"Intermediate Risk\",\n \"High Risk\"\n ],\n \"result\": \"Intermediate Risk\",\n \"result_description\": \"You have an intermediate likelihood to experience depressive symptoms. However, anyone can experience depression, and most people will experience depression at least briefly in their lifetimes.\",\n \"risk_management\": \"Medical treatments for depression include medication, exercise, sun exposure, and sun lamps (especially in northern latitudes). A strong social support system can help reduce your feelings of depression. If you do experience depression, consult your doctor immediately, as these symptoms can quickly escalate and disrupt your daily life.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Depression is highly affected by pituitary functions. Aside form moral support and rest, it is also suggested that you explore lifestyle changes as well as medical support, such as psychiatric consultations or therapy.\",\n \"about\": \"Depression (major depressive disorder) is a common and serious medical illness that negatively affects how you feel, think, and act. Depression causes feelings of sadness and/or a loss of interest in activities you once enjoyed. \\n\\nIt can lead to a variety of emotional and physical problems and can decrease a person’s ability to function at work and at home.\",\n \"caption\": \"A serious medical condition affecting your mood and cognition.\",\n \"GENES\": {\n \"Intergenic\": {\n \"rs782207\": {\n \"genotype\": \"AG\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"LOC105372648- ARFGEF2\": {\n \"rs6066909\": {\n \"genotype\": \"CT\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"KSR2\": {\n \"rs7973260\": {\n \"genotype\": \"AG\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Loneliness\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"Your have an intermediate likelihood to experience loneliness. If you do feel lonely frequently, you may try involving yourself in community programs for an important cause, connecting with new people, or engaging in group sports and exercise activities, such as spin classes. \",\n \"risk_management\": \"Loneliness can affect anyone, regardless of their genetics, social status, or family life. \\nScheduling regular interactions with other people can be helpful.\\nWork to socialize if your occupation naturally involves loneliness, such as truck driving, medicine, engineering, or some office work.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Loneliness is highly associated with depression and other mental health conditions. Being aware of your risk can help you plan ahead and reduce the risk of loneliness manifesting in your life.\",\n \"about\": \"Loneliness is not simply the act of being alone, but the negative emotions that come as a result. While isolation is sometimes associated with introverted personalities, an introverted person may feel great sadness from a lack of socialization, while an otherwise extraverted person may not suffer at all from loneliness. Younger people (18-22) are also more likely to experience feelings of loneliness, regardless of their genetics. \",\n \"caption\": \"How being alone affects you.\",\n \"GENES\": {\n \"TCF4\": {\n \"rs613872\": {\n \"genotype\": \"TT\",\n \"text\": \"High likelihood\"\n }\n },\n \"NMUR2\": {\n \"rs9285647\": {\n \"genotype\": \"GG\",\n \"text\": \"High likelihood\"\n }\n },\n \"EPB41L2\": {\n \"rs9385564\": {\n \"genotype\": \"AA\",\n \"text\": \"High likelihood\"\n }\n },\n \"ARFGEF2\": {\n \"rs1983639\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n },\n \"GBE1\": {\n \"rs4465966\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n },\n \"ERBB4\": {\n \"rs6727114\": {\n \"genotype\": \"CC\",\n \"text\": \"High likelihood\"\n }\n },\n \"NMUR2@DUB978\": {\n \"rs1010254\": {\n \"genotype\": \"CT\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"OR1S1\": {\n \"rs1966836\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n },\n \"NDUFS3\": {\n \"rs10838738\": {\n \"genotype\": \"AG\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Resilience\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Low Likelihood\",\n \"result_description\": \"Your genetic make-up suggests that you are turbulent and easily stressed.\",\n \"risk_management\": \"Whenever faced with challenging and stressful circumstances, deep breathing exercises, meditation, a healthy diet, and regular exercise can help. There are no quick fixes for stress, but stress is often an indicator that you should make a change in your life: use it as a warning sign to prevent stress from building up and causing unhealthy side effects. If prolonged stress is unavoidable and is affecting your psyche, it is suggested to talk to a psyciatrist for help.\\n\\nDiagnostic Test\\nMyer Briggs Personality Test\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Knowing your genetic predisposition to resilience may help you understand why some stressful circumstances in your life have affected you in certain ways. You can also develop new coping mechanisms, such as meditation and regular exercise, if you do find yourself frequently getting stressed out.\",\n \"about\": \"Resilience is your ability to recover from stress. Studies of African Americans found that the LINC01221 gene was strongly correlated with differences (and potential improvements) in resilience. \",\n \"caption\": \"How quickly you bounce back.\",\n \"GENES\": {\n \"LINC01221\": {\n \"rs322931\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Instant Gratification\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"High Likelihood\",\n \"result_description\": \"You may have trouble resisting instant gratification. Unhealthy conveniences, such as fast food or skipping a gym session, may be more appealing to you. This trait can have serious negative side effects in the long run.\",\n \"risk_management\": \"Instant gratification often comes at a price: it's easier to eat snack food than to cook a healthy meal. It's also easier to watch TV than to complete a workout. \\n\\nPracticing your ability to wait for gratification can improve your odds of success in many areas of life, including your health, career, weight loss, and more. \\n\\n\\\"Temptation bundling\\\" is an effective technique for living a healthier life. In this method, you combine instant gratification with long-term health goals. For example, you might limit yourself to watching Netflix only while using a stationary bike, or only allow yourself to eat at a restaurant if you walk or bike there (instead of driving).\\n \\nApplicable Test: \\nThe Delay of Gratification Test for Adults (DoG-A) includes four types of rewards that are meaningful to adults, namely: snacks, real money, hypothetical money, and magazines. Four subscores and two composite scores can be calculated, giving you a clearer idea of your need for instant gratification.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"These genes can determine your predisposition to obesity, addiction, ADHD, depression, schizophrenia, and other conditions. This is also critical in managing behaviors that can have a long-term consequences for your mental and physical health.\",\n \"about\": \"Instant gratification is the need for immediate rewards. People with an inclination toward instant gratification may take smaller, less desirable rewards that are available sooner, instead of bigger rewards that require a waiting period. This trait is correlated with substance abuse, addiction, and obesity.\",\n \"caption\": \"Your ability to wait for greater rewards in the future.\",\n \"GENES\": {\n \"GPM6B\": {\n \"rs6528024\": {\n \"genotype\": \"CC\",\n \"text\": \"High likelihood\"\n }\n }\n }\n },\n \"Risk taking\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"You have an intermediate likelihood of risk-taking behavior. \",\n \"risk_management\": \"Taking intelligent risks can help accelerate your career and bring you closer to success. Unhealthy risks, however, can be potentially lethal. Avoid unnecessary risks for the sake of entertainment, and apply your risk-taking inclinations towards your career and personal ambitions to improve your life and obtain new rewards.\\n\\nAPPLICABLE TEST:\\nBrain imaging to monitor neural networks related to risky behavior using Functional Magnetic Resonance Imaging (fMRI) and Diffusion Tensor Imaging (DTI) techniques.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Risk-taking challenges the brain's capacity for learning, decision making, coping strategies, and general cognitive development. This can also help in designing educational approaches and methodologies directed towards high- and low-risk-takers. \",\n \"about\": \"In a study of European people, it was found that risk-taking was positively correlated with attaining a university degree; while risk-taking may seem like a bad thing, it's generally useful and can be critical to achieving success in an uncertain world. Those without the genetic predisposition towards taking risks can still build up the courage and tenacity to do so.\",\n \"caption\": \"Not all risks are bad!\",\n \"GENES\": {\n \"SOX2\": {\n \"rs7632216\": {\n \"genotype\": \"GA\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Morningness\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"You have an intermediate likelihood of being a morning person.\",\n \"risk_management\": \"Coffee can help you wake up, but your natural energy levels may be hard to change. Figuring out what time of day you feel most alert and focused can help you schedule your day more efficiently.\\n\\nAPPLICABLE TEST. The Horne and Ostberg Morningness/Eveningness Questionnaire (MEQ) which is a subjective tool for differentiating chronotype.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Individuals with a morning chronotype (body clock) who exhibit extreme morning tendencies (e.g., a tendency to get up early in the morning, perform their best in the morning hours, and go to bed early in the evening) are called \\\"early Larks.\\\" Knowing when to schedule your work or exercise can help maximize your efficiency and improve your mood. \\n \",\n \"about\": \"Morningness is a trait wherein a person starts and finishes their day early. Morning people typically wake up around 6am and go to sleep around 10:00 pm. They are usually more energetic during the morning, thus they are well suited for early morning shifts. \",\n \"caption\": \"Are you a morning person?\",\n \"GENES\": {\n \"RGS16 (RNASEL)@DUB323\": {\n \"rs1144566\": {\n \"genotype\": \"CC\",\n \"text\": \"Low likelihood\"\n }\n },\n \"VIP\": {\n \"rs9479402\": {\n \"genotype\": \"TT\",\n \"text\": \"Low likelihood\"\n }\n },\n \"PER2\": {\n \"rs55694368\": {\n \"genotype\": \"GT\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"HCRTR2\": {\n \"rs35833281\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n },\n \"PER3\": {\n \"rs11121022\": {\n \"genotype\": \"CA\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"APH1A\": {\n \"rs34714364\": {\n \"genotype\": \"TG\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"TOX3\": {\n \"rs12927162\": {\n \"genotype\": \"AA\",\n \"text\": \"High likelihood\"\n }\n },\n \"FTO\": {\n \"rs1421085\": {\n \"genotype\": \"TT\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Social Rejection\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Low Likelihood\",\n \"result_description\": \"You have a low tendency to feel social rejection. Your genetics reveals that you have a tendency to be stoic and phlegmatic, although constant experience of rejection can still lead to a number of psychological problems ranging from loneliness to depression.\",\n \"risk_management\": \"You may have the tendency to enjoy alone time more than social engagement. Meaningful connections to a small number of people, rather than large amounts of superficial relationships, low maintenance friendships are more managable to you.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Understanding your response to social rejection can help bring some past experiences to light and help you cope with future feelings of rejection or sadness.\",\n \"about\": \"Social rejection can be painful for anyone, but your genes can increase your response and worsen feelings of sadness in response to rejection. It's important to remember that your value as a human being is inherent, not dependent on the actions of others, and that most rejection happens as the result of a misunderstanding or a lack of familiarity.\",\n \"caption\": \"How rejection affects you.\",\n \"GENES\": {\n \"OPRM1\": {\n \"rs1799971\": {\n \"genotype\": \"AA\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Hypnotizability\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"High Likelihood\",\n \"result_description\": \"You have a high likelihood of being easily hypnotized. \",\n \"risk_management\": \"There is no risk management for hypnosis, because it's not generally a negative thing. In fact, hypnosis can often provide relief for those in pain or those with high levels of anxiety.\\n\\nHypnotic Induction Profile test can be performed to assess hypnotizability range of a person. \",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Hypnosis is often used by medical practitioners as a method for reducing pain or stress, even during extremely difficult treatments, like those for cancer.\",\n \"about\": \"During hypnosis, a person becomes deeply relaxed and more open to suggestion. They may be easily persuaded to do things they would not otherwise do, and are often free of inhibitions. Hypnotizability is your likelihood of being hypnotized under normal settings. \",\n \"caption\": \"How easily are you hypnotized?\",\n \"GENES\": {\n \"COMT\": {\n \"rs4680\": {\n \"genotype\": \"GG\",\n \"text\": \"High likelihood\"\n }\n }\n }\n },\n \"Impulsivity\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"You have a typical tendency to become impulsive. \",\n \"risk_management\": \"You may or may not have a plan before executing things. However, your environment, upbringing, and state of mind can also affect your impulsivity.\\n\\nTo reduce impulsivity, you can try:\\n \\n1. Improving self-control \\n2. Developing coping skills \\n3. Learning to temper and tame your impulsive behavior by increasing self-awareness \\n4. Finding an accountability partner or friend who can help curb your spur-of-the-moment decision\\n5. Practice meditation and mindfulness \\n\\nTo test whether or not you are impulsive, one can answer a widely-used instrument to measure dysfunctional impulsivity by Dr. Scott Dickman. \",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Impulsivity is an important dimension of normal behavior: for many of life’s challenges, it is vital to be able to initiate behavior, to take action, and to explore uncertain and potentially dangerous situations without much time for thinking or analyzing all the potential outcomes. \",\n \"about\": \"Impulsivity is a tendency to take action without prior planning, reflection, or consideration for the consequences. This trait is a component of some psychiatric problems such as ADHD, bipolar disorder, and antisocial disorders, but having high impulsivity does not make you more likely to experience those issues.\\n\\nImpulsivity is broadly defined as “actions without foresight” that are “poorly conceived, prematurely expressed, unduly risky, or inappropriate to the situation, and that often result in undesirable outcomes.\\\"\",\n \"caption\": \"Fast, thoughtless actions.\",\n \"GENES\": {\n \"5-HT1A\": {\n \"rs6295\": {\n \"genotype\": \"GC\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Positive Affectivity\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Low Likelihood\",\n \"result_description\": \"Based on your genetics, you have a harder time experiencing positive emotions such as satisfaction, enthusiasm, or happiness. \",\n \"risk_management\": \"Having a positive affect is largely beneficial to your health, mood, and performance. Positivity can make it easier to stay focused and productive, improve your social interactions, and reduce the effects of depression, especially temporary depression caused by specific events or a lack of sunlight (seasonal affective disorder, or \\\"SAD\\\"). Constant lack of possitive emotions can also be correlated to hormonal defficiencies of domapine and other neurotransmitters.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Getting joy from the little things in life can improve your overall health and mood. If you have a low genetic likelihood of a positive affect, consider consciously developing a habit of positivity. \",\n \"about\": \"Positive affectivity refers to an individual experiencing positive moods such as joy, interest, and alertness. It also usually refers to a mild happy or pleasant feeling, induced in some simple way. People with a positive affect may smile or be amused at something small, such as a great cup of coffee, while other people have a harder time experiencing happiness.\",\n \"caption\": \"Joy, happiness, and alertness.\",\n \"GENES\": {\n \"LINC01221\": {\n \"rs322931\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n },\n \"LINC01221@DUB579\": {\n \"rs322931\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Emotional Support Seeking\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"You have an intermediate likelihood of seeking emotional support. \",\n \"risk_management\": \"Seeking emotional help is a normal process in many cultures, especially during stressful situations. However, your environment, upbringing, and genes will have a great influence on your likelihood of seeking emotional support. Since you do not have an increased likelihood of naturally seeking emotional support, you may have to consciously \\\"swallow your pride\\\" and seek out help when needed.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Your life expectancy and quality of life are directly affected by your willingness to seek emotional support. Rather than seeing this as a weakness, you should consider it a sign of strength and a source of support and inspiration.\",\n \"about\": \"Your ability to seek emotional support is a critical tool for your mental and physical wellbeing. Emotional support can help you weather difficult challenges and emotional turmoil.\",\n \"caption\": \"How likely you are to get help when you need it.\",\n \"GENES\": {\n \"OXTR \": {\n \"rs53576\": {\n \"genotype\": \"GA\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Optimism\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"You have an intermediate likelihood of being optimistic.\",\n \"risk_management\": \"Optimism is a positive and useful trait. Consciously seeking out the positive possibilities during negative events and personal challenges can improve your mood and increase your chances of succeeding in your career and personal life. If you find it difficult to be optimistic, meditation and social support can help.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"The OXTR gene codes for the receptor of oxytocin, a hormone that contributes to positive emotion and social bonding. Because of this, the OXTR gene is a good predictor of someone's optimism. \",\n \"about\": \"Optimism is the ability to imagine positive outcomes during difficult challenges. Rather than simply being delusional, optimistic people are able to see realistic, yet positive, possibilities.\",\n \"caption\": \"Internal positivity in the face of external negativity.\",\n \"GENES\": {\n \"OXTR \": {\n \"rs53576\": {\n \"genotype\": \"GA\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Aggressive Behavior\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"Based on preliminary data, you have an intermediate likelihood for aggressive behavior.\",\n \"risk_management\": \"Aggressive behavior can damage family relationships, ruin your career, and make life generally unpleasant. Mindfulness meditation, stress-relieving exercises, and actively practicing empathy can reduce your tendency for aggressive behavior and improve your chances of success.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Aggressive behavior may have evolved as a tool for establishing dominance and control in uncertain environments, but it is often harmful to both the individual and society in general, especially in a modern world that requires cooperation and social bonding for business and personal success.\",\n \"about\": \"Aggression is a multi-dimensional concept, but it can be generally defined as any behavior that inflicts pain or harm on another person.\",\n \"caption\": \"Negative, harmful behaviors.\",\n \"GENES\": {\n \"OXTR\": {\n \"rs53576\": {\n \"genotype\": \"AG\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Reward Dependence\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Low Likelihood\",\n \"result_description\": \"You have a low likelihood of being reward dependent.\",\n \"risk_management\": \"If the rewards of your job are not particularly appealing to you, you may not be motivated to do your best work. It may be more important for you to find work that is intrinsically motivating (inherently enjoyable). \",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Reward dependence can sometimes lead to disorders and negative consequences, such as when someone relies too heavily on social approval and allows themselves to suffer in relationships to make other people happy.\",\n \"about\": \"Social approval, monetary rewards, and congratulatory remarks can drive some people more heavily than others.\",\n \"caption\": \"Everybody's working for the weekend.\",\n \"GENES\": {\n \"CSMD3\": {\n \"rs4436153\": {\n \"genotype\": \"TC\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"EGR2\": {\n \"rs10995356\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n },\n \"C21orf45\": {\n \"rs2833693\": {\n \"genotype\": \"TT\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Harm Avoidance\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"You have an intermediate likelihood to avoid harm (rather than seeking rewards).\",\n \"risk_management\": \"You do not have an increased likelihood of avoiding harm, which can help you pursue risky rewards in life.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Persons with the Harm Avoidance personality trait were more prone to developing increased anxiety, insomnia, migraines, and depression. Accepting a normal level of negativity in life can reduce the mental fatigue of resisting it.\",\n \"about\": \"Harm avoidance is strongly tied to excessive worrying, pessimism, shyness, and being fearful, doubtful, and easily fatigued.\",\n \"caption\": \"Avoiding harm can (ironically) be quite painful.\",\n \"GENES\": {\n \"SLC39A10\": {\n \"rs10172965\": {\n \"genotype\": \"CC\",\n \"text\": \"High likelihood\"\n }\n },\n \"SLA, TG\": {\n \"rs2741200\": {\n \"genotype\": \"TC\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"APBA2\": {\n \"rs17680945\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Gambling\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"High Likelihood\",\n \"result_description\": \"You have a high likelihood of developing a gambling habit. \",\n \"risk_management\": \"Gambling can quickly become problematic and is almost never beneficial. Gambling relies on a logical fallacy and a belief in chance that is not supported by mathematical odds. If you don't already gamble, it's best not to start, and it can quickly escalate into a real financial and psychological problem.\\n\\n1. The biggest step to overcoming a gambling addiction is realizing that you have a problem. \\n2. Learn to relieve unpleasant feelings in healthier ways, such as exercise or social engagement. \\n3. Strengthen your support network. \\n4. Join a peer-support group. \\n5. Seek help for underlying mood disorders. \\n6. Finding alternatives to gambling (try new sports, hobbies, or sources of excitement).\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Gambling is harmful to your psychological and physical health. People who live with this addiction may experience depression, migraines, distress, intestinal disorders, and other anxiety-related problems. As with other addictions, the consequences of gambling can lead to feelings of despondency and helplessness. Too much time spent gambling can also lead to relationship and legal problems, job loss, mental health problems, and even suicide.\",\n \"about\": \"Obsessive gambling is an impulse control disorder and a 'behavioral' addiction. This is influenced by biological factors such as serotonergic, noradrenergic, and dopaminergic dysfunction (problems with the reward chemicals of the brain). Associations have been reported between pathological gamblers and allele variants of polymorphisms at dopamine receptor genes, the serotonin transporter gene, and the monoamine oxidase A gene.\\n\\nSimply put, your desire to gamble, even in the face of continued losses, may be partly genetic. \",\n \"caption\": \"The house always wins.\",\n \"GENES\": {\n \"PLTP\": {\n \"rs6065904\": {\n \"genotype\": \"GG\",\n \"text\": \"High likelihood\"\n }\n },\n \"MT1X\": {\n \"rs8064100\": {\n \"genotype\": \"GA\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"VLDLR-AS1\": {\n \"rs4741732\": {\n \"genotype\": \"AA\",\n \"text\": \"High likelihood\"\n }\n },\n \"FZD10-AS1\": {\n \"rs11060736\": {\n \"genotype\": \"TT\",\n \"text\": \"Low likelihood\"\n }\n },\n \"ATXN1\": {\n \"rs9383153\": {\n \"genotype\": \"AA\",\n \"text\": \"High likelihood\"\n }\n },\n \"PRKCE\": {\n \"rs7591351\": {\n \"genotype\": \"TT\",\n \"text\": \"High likelihood\"\n }\n },\n \"XYLT1\": {\n \"rs3943418\": {\n \"genotype\": \"AG\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Hearing Function\": {\n \"result_options\": [\n \"Low risk\",\n \"Intermediate risk\",\n \"High risk\"\n ],\n \"result\": \"High risk\",\n \"result_description\": \"You have a high likelihood of age-related hearing loss. \",\n \"risk_management\": \"You should avoid loud environments that could further increase your risk of auditory failure. If you know that you will be traveling to places with extreme noises, you may equip yourself with hearing protection, such as foam earplugs, earmuffs, or custom hearing protection. \\n\\nUse low-volume settings on your electronic and musical devices. Exercise caution when taking medicines that may affect hearing, such as Aspirin, NSAIDs like Ibuprofen and naproxen, some antibiotics like aminoglycosides, loop diuretics like furosemide, and cancer medicines like cisplatin, bleomycin, and cyclophosphamide. In advanced cases of hearing damage, a hearing aid device may be recommended.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Knowing your risk of hearing loss may help you delay its onset and alleviate the risk of depression.\",\n \"about\": \"As we age, we gradually lose our sense of hearing. The following genetic variants are linked to age-related hearing impairment; they also influence nervous system processes, such as cognition, learning, and memory. Hearing loss is also a known risk factor for depression and dementia. \",\n \"caption\": \"What did you say?\",\n \"GENES\": {\n \"SIK3\": {\n \"rs681524\": {\n \"genotype\": \"TT\",\n \"text\": \"High likelihood\"\n }\n },\n \"ARHGEF28\": {\n \"rs6453022\": {\n \"genotype\": \"CC\",\n \"text\": \"High likelihood\"\n }\n },\n \"TYR\": {\n \"rs1806319\": {\n \"genotype\": \"CT\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"EYA4\": {\n \"rs9493627\": {\n \"genotype\": \"GG\",\n \"text\": \"High likelihood\"\n }\n },\n \"BAIAP2L2\": {\n \"rs132930\": {\n \"genotype\": \"AG\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"TRIOBP\": {\n \"rs9610841\": {\n \"genotype\": \"CC\",\n \"text\": \"High likelihood\"\n }\n },\n \"NID2\": {\n \"rs1566128\": {\n \"genotype\": \"GG\",\n \"text\": \"High likelihood\"\n }\n },\n \"PHLDB1\": {\n \"rs11603023\": {\n \"genotype\": \"TT\",\n \"text\": \"Low likelihood\"\n }\n },\n \"FTO\": {\n \"rs62033400\": {\n \"genotype\": \"AA\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Mathematical Ability\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"High Likelihood\",\n \"result_description\": \"Your genotype is associated with a high level of mathematical ability; you should be able to grasp analytical concepts rather than abstract ideas.\",\n \"risk_management\": \"\\\"Nootropic (cognitive) supplements can help facilitate and improve brain function and memory. Ginkgo biloba improves cognitive function by promoting improved blood circulation to the brain and is protective against neural damage. Fish oil benefits memory because of the Omega-3 fatty acids, like DHA and EPA, that play important roles in brain function and development. Glutamate supplementation functions as an excitatory neurotransmitter in the nerve cells of the brain. However, intelligence is highly cultivated by environment, studying, learning, and practice.\\n\\nFor children, the most common test is to practice counting backwards or completing other straightforward exercises designed to relate numbers (e.g Neuropsychological Test Battery for Number Processing and Calculation in Children).\\\"\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Research shows that a person's mathematical ability is also linked to a genetic variation in the SPOCK1 gene. Therefore, assessing this gene may help you address certain issues dealing with numbers and logic, or may offer the opportunity to capitalize on your unique abilities.\",\n \"about\": \"Certain people can quickly learn logic, arts, and languages, while others prefer sciences, like biology and chemistry. Mathematical ability is a complex trait that involves neurological and cognitive development, which can be honed through education and training. \",\n \"caption\": \"Are numbers built into your DNA?\",\n \"GENES\": {\n \"SPOCK1\": {\n \"rs11743006\": {\n \"genotype\": \"CC\",\n \"text\": \"High likelihood\"\n }\n }\n }\n },\n \"Intelligence\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Low Likelihood\",\n \"result_description\": \"Genetically, you are more likely to have low cognitive abilities and slower thought processes, but this can be improved with education, practice, and exercise.\",\n \"risk_management\": \"Proper education and training can further develop your critical thinking abilities. Avoid brain-damaging habits like sleepless nights, stressful lifestyle choices, and excess sugar consumption. Supplements that offer cognitive enhancements, like Ginkgo Biloba that increase brain blood flow and Phosphatidylserine required for the formation and maintenance of strong cell membranes and healthy neurotransmissions, can improve your learning abilities. \\n\\nThe most widely used intelligence tests includes: \\n1. Stanford-Binet Intelligence Scale: meant to gauge intelligence through five factors of cognitive ability. These five factors include fluid reasoning, knowledge, quantitative reasoning, visual-spatial processing, and working memory. Both verbal and nonverbal responses are measured. 2. Wechsler Adult and Child Intelligence Scales: provide four individual index scores for the major components of intelligence, including verbal comprehension, perceptual reasoning, working memory, and processing speed.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Specific variations in these genes influence a person's production of new brain cells, as well as the protection of nerves, enabling faster thought processes. \",\n \"about\": \"Intelligence is a general cognitive ability that enables a person to perform mental tasks, solve problems, and make sound decisions. It can also influence dexterity. High intelligence involves an improved ability to solve problems.\",\n \"caption\": \"Genetic intelligence and cognitive skills.\",\n \"GENES\": {\n \"RNA5SP45, FOXO6\": {\n \"rs10889959\": {\n \"genotype\": \"TT\",\n \"text\": \"Low likelihood\"\n }\n },\n \"AL451062.3, ST3GAL3\": {\n \"rs2428963\": {\n \"genotype\": \"CT\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"PTPRF\": {\n \"rs539096\": {\n \"genotype\": \"AA\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Verbal Memory\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"You have an intermediate likelihood of verbal recall.\",\n \"risk_management\": \"While your genetic capacity for memory is fixed at birth, you can drastically improve your memory performance by practicing mnemonics, such as the Method of Loci, in which you associate items (such as numbers you need to remember) with a familiar location (such as your living room). As you age, getting frequent memory tests can help assess whether you are experiencing age-related declines in memory function. Exercise is a well-documented method for improving cognitive performance.\\n\\nTests Include:\\n1. Cognitive tests to gauge memory, problem-solving skills, and immediate recall. \\n2. MRI or CT scan to assess if there are any physical causes for poor memory performance.\\n3. Various types of Verbal Learning Tests (VLT), such as California VLT and Rey Auditory VLT, to evaluate long term memory recall efficiency.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Variations in the TOMM40 and PVRL2 genes have been shown to be associated with both immediate and delayed verbal memories.\",\n \"about\": \"Verbal memory is one's ability to remember concepts, events, or thoughts that has been verbally presented either recently or in the past. This trait is linked to distinct cognitive processes that can retrieve recently-presented or learned information.\",\n \"caption\": \"How well you remember?\",\n \"GENES\": {\n \"TOMM40\": {\n \"rs2075650\": {\n \"genotype\": \"AG\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"PVRL2\": {\n \"rs157582\": {\n \"genotype\": \"CT\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Musical Ability\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Low Likelihood\",\n \"result_description\": \"Your result is associated with a low likelihood of having a good musical ability. \",\n \"risk_management\": \"Practice and consistency are far more important than genetics in determining your musical ability. Even if music does not become a career for you, practicing music can improve your cognitive abilities and general intelligence. Muscle memory can also contribute to musical passion and can help in developing musical ability.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Early development of musical abilities is crucial to long-term success in music. Even for those who are not genetically gifted in music, practicing music can have many cognitive and emotional benefits.\",\n \"about\": \"Musical ability is partly determined by your genetics. In one study, the ability to accurately reproduce a given pitch was tied to this particular SNP.\",\n \"caption\": \"Do you have the \\\"Mozart\\\" gene?\",\n \"GENES\": {\n \"UGT9\": {\n \"rs4148254\": {\n \"genotype\": \"CC\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Sensitivity to Stimuli\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Low Likelihood\",\n \"result_description\": \"You have a low likelihood of being sensitive to your environment, and you may miss events that happen around you.\",\n \"risk_management\": \"Outside stimuli should have less of an effect on you, but if you find that you do react strongly to events and other people, mindfulness meditation, plenty of sleep, and a diet free from alcohol can help reduce your reactivity.\\n\\n1. Highly Sensitive Person Test \\n2. Adult Self-Report Scale (ASRS) Screener will help you recognize the signs and symptoms of adult ADHD, which is related to a high sensitivity to stimuli. The ASRS is comprised of 6 questions that are ranked on a scale of 0 to 4. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Since this trait is deeply rooted in the nervous system, a wide number of genes are involved in this trait. Variability in these genes can make you either highly sensitive or highly unresponsive to your surroundings.\",\n \"about\": \"Responding to subtle stimuli, or being easily hyper-aroused by stimuli, can indicate that you are highly sensitive to external events and triggers.\",\n \"caption\": \"How easily do you respond to stimuli?\",\n \"GENES\": {\n \"DBH \": {\n \"rs1611123\": {\n \"genotype\": \"CT\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"NTSR2 \": {\n \"rs7131056\": {\n \"genotype\": \"CC\",\n \"text\": \"Low likelihood\"\n }\n },\n \"DRD2\": {\n \"rs7575374\": {\n \"genotype\": \"AA\",\n \"text\": \"Low likelihood\"\n }\n }\n }\n },\n \"Cognitive Control \": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"High Likelihood\",\n \"result_description\": \"Your genetics suggest that you have a high likelihood of being a multi-tasker. You tend to switch tasks with ease. This means that your brain can easily adapt to rapid changes in information.\",\n \"risk_management\": \"Stress, pressure, and lack of sleep can all damage your cognitive abilities. Regular exercise is crucial to improving your mental health and performance.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Cognitive control plays an important role in human intelligence and performance, but can be improved over time.\",\n \"about\": \"Cognitive control is the process of adjusting your behavior to achieve your goals. This process can inhibit automatic responses and influence working memory. Cognitive control can either lower or increase your mental flexibility: more cognitive stability means less flexibility, and vice-versa.\",\n \"caption\": \"Controlling automatic or unwanted responses.\",\n \"GENES\": {\n \"COMT\": {\n \"rs4680\": {\n \"genotype\": \"GG\",\n \"text\": \"High likelihood\"\n }\n }\n }\n },\n \"Educational Attainment \": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Intermediate Likelihood\",\n \"result_description\": \"Your genes suggest that you will spend an average amount of time furthering your education.\",\n \"risk_management\": \"Educational attainment is not written in stone (nor in your genes). Personal ambition, access to financial resources, and your support systems can improve your chances of excelling in an academic setting. These genes only predict what you are likely to have achieved, but do not limit what you are capable of achieving. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"While income and environment strongly influence the amount of formal education a person completes, the genes associated with this trait influence brain development, cognitive function, and personality, which all play a significant and measurable role in your education. Moreover, this trait is very helpful in identifying children who need special attention, vigilance, and greater support.\",\n \"about\": \"Educational attainment refers to the highest level of education that an individual has completed. Research shows that there are certain genetic variations that can influence the number of years spent getting an education. \",\n \"caption\": \"Your DNA's impact on your education.\",\n \"GENES\": {\n \"AMT\": {\n \"rs11706370\": {\n \"genotype\": \"AG\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"intergenic\": {\n \"rs7029718\": {\n \"genotype\": \"AG\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"intergenic@DUB238\": {\n \"rs1487441\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n },\n \"intergenic@DUB480\": {\n \"rs4851266\": {\n \"genotype\": \"CT\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"ELOVL7\": {\n \"rs6872863\": {\n \"genotype\": \"GG\",\n \"text\": \"High likelihood\"\n }\n },\n \"SUOX\": {\n \"rs1701704\": {\n \"genotype\": \"TG\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"MEF2C\": {\n \"rs4518438\": {\n \"genotype\": \"CC\",\n \"text\": \"Low likelihood\"\n }\n },\n \"PTPRF\": {\n \"rs2494995\": {\n \"genotype\": \"AC\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"CADM2\": {\n \"rs62263923\": {\n \"genotype\": \"AA\",\n \"text\": \"Low likelihood\"\n }\n },\n \"ARMH3\": {\n \"rs10748815\": {\n \"genotype\": \"GA\",\n \"text\": \"Intermediate likelihood\"\n }\n },\n \"LRRN2\": {\n \"rs11588857\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n },\n \"GPR112\": {\n \"rs2073236\": {\n \"genotype\": \"CC\",\n \"text\": \"High likelihood\"\n }\n }\n }\n },\n \"Perceptual speed\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"Low Likelihood\",\n \"result_description\": \"Your genes are associated with slower perceptual speeds. This means that you can precieve your environment and process reaction slower than average.\",\n \"risk_management\": \"Improving your perceptual speed requires practice and nutrition: your brain's chemicals are highly dependent on the foods you consume. To boost your brain's health, eat plenty of omega-3 and antioxidants, as well as healthy levels of caffeine. Increase in Vitamin B complex will also enhance brain synapses for better reaction to the environment.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Genetic variations in dopamine-pathway genes, as well as other brain-derived neurotrophic factor genes, influence your perceptual speed. \",\n \"about\": \"Perceptual speed refers to the ability to accurately (and completely) compare letters, numbers, objects, pictures, or patterns. It is not directly tied to intelligence, however: some people may process information more slowly, but can still be highly intelligent.\",\n \"caption\": \"How fast is your brain?\",\n \"GENES\": {\n \"DRD4\": {\n \"rs3756450\": {\n \"genotype\": \"AA\",\n \"text\": \"Low likelihood\"\n }\n },\n \"BDNF\": {\n \"rs6265\": {\n \"genotype\": \"CT\",\n \"text\": \"Intermediate likelihood\"\n }\n }\n }\n },\n \"Creativity\": {\n \"result_options\": [\n \"Low Likelihood\",\n \"Intermediate Likelihood\",\n \"High Likelihood\"\n ],\n \"result\": \"High Likelihood\",\n \"result_description\": \"Your genes suggest that you have a high level of creativity. \",\n \"risk_management\": \"There are many ways to boost your creativity. Maintain high creativity by walking, surrounding yourself with inspiring objects, visiting a new environment, or giving yourself restrictions. Immersing yourself with the arts and literature can help you come up with new ideas and solutions. \",\n \"star_rating\": 1,\n \"snp_table_caption\": \"A high propensity for creativity can help guide you to a career path that utilizes your strength as a creative thinker.\",\n \"about\": \"Creativity is the ability to generate new ideas and solutions. This skill is useful in many otherwise non-creative fields, such as mathematics, science, and engineering, but can also be helpful in the arts, marketing, and design.\",\n \"caption\": \"New ideas and possibilities.\",\n \"GENES\": {\n \"COMT\": {\n \"rs5993883\": {\n \"genotype\": \"GG\",\n \"text\": \"Low likelihood\"\n }\n },\n \"SNAP25\": {\n \"rs362584\": {\n \"genotype\": \"GG\",\n \"text\": \"High likelihood\"\n }\n },\n \"KATNAL2 \": {\n \"rs2576037\": {\n \"genotype\": \"TT\",\n \"text\": \"High likelihood\"\n }\n }\n }\n }\n }\n}"},{"id":"f276e380-186c-4de0-a249-4f9bcf39d7c8","name":"Personality And Cognition Report - Missing Required Parameter","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1c2b7b12b289_709f9fd16bb5_8aafce768660\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/pc/report"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"7a76e31795886492401de5ac37447ad5\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"cb900451-4499-473d-aa50-66747b70ea29"},{"key":"X-Runtime","value":"0.003554"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Required parameter 'customer_id' missing\",\n \"report_json\": {}\n}"}],"_postman_id":"d1ad473a-54e2-4953-932a-6ccd6686fa19"},{"name":"Skincare Report","id":"12c16138-9ae4-458b-b6fc-76901a85833f","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/skincare/report","description":"

Description: This Endpoint generates/retrieves the latest skincare report for any customer

Request Parameters:

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","urlObject":{"path":["request","skincare","report"],"host":["{{base_url}}"],"query":[],"variable":[]}},"response":[{"id":"201421b7-fbe1-4469-9ba4-e9cc04e041ad","name":"Skincare Report Successful Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1c2b7b12b289_709f9fd16bb5_8aafce768660\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/skincare/report"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"01cd82ee368e377c7cf2be60c9ce4a46\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"82b0065d-3a12-4669-8f21-cedd8186d5b6"},{"key":"X-Runtime","value":"0.017627"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Skincare Report Generated\",\n \"report_json\": {\n \"skin type\": {\n \"goal_result\": \"Normal\",\n \"goal_result_description\": \"Your skin should be easy to take care of, with most cleansers and moisturizers working well for you. Use natural skincare products, stay hydrated, and avoid excess sun exposure. Regular exercise and a good diet can also improve your skin's quality and health.\",\n \"TRAITS\": {\n \"SKIN SENSITIVITY\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Based on your genetics, your results are associated with a lower risk of having sensitive skin.\",\n \"risk_management\": \"Identifying your reaction to particular ingredients can be difficult, especially when many skin products use the same ingredients. It may also take several days for symptoms to reveal themselves, so trying a product for one day (or removing it from your routine for a day) is not enough to accurately identify your sensitivities.\\n\\nSkin testing is the best way to accurately determine your unique sensitivities. It is done by observing the reaction of the skin to an allergen through scratching or injecting the substance and observing the individual's reaction time and severity of irritation. \\n\\nThe skin will also be exposed to UV rays to determine how sensitive it is to sun damage. After the test, mild cortisone will be applied and cleaning of the dermis will be made to ensure the removal of all allergens. This test must be performed in a professional medical setting to avoid unwanted infections and skin damage. Speak with your dermatologist to see if this test is necessary. \",\n \"star_rating\": 2,\n \"snp_table_caption\": \"The table shows the different genes and polymorphisms that affect your skin's response to everyday irritants and how fast your body can trigger an immune response to fight the irritant. People with a high skin sensitivity will experience more damage as a result of exposure to these irritants and conditions.\",\n \"about\": \"Skin sensitivity is a trait that covers a complex spectrum of skin-related phenotypes that cause the skin to age faster and reduce the overall health of the skin cells. Sensitivities affect the skin in different ways, but they often result to similar reactions in the skin. These include sunburn, skin pigmentation, and even some skin-related conditions such as inflammation, acne, psoriasis, contact dermatitis, rosacea, eczema and others.\",\n \"caption\": \"Your skin's reaction to the outside world\",\n \"active_ingredients\": {\n \"Aloe vera\": {\n \"description\": \"Aloe vera is a humectant, which means it binds water to your skin to combat dehydration and maintain moisture. It's also antibacterial, which keeps the skin healthy and breakout-free.\"\n },\n \"Green tea\": {\n \"description\": \"Green tea is packed with powerful antioxidants, which stave off fine lines, age spots, and prevent the breakdown of collagen.\"\n },\n \"Vitamin C\": {\n \"description\": \"Vitamin C brightens skin and stimulates collagen production for radiant, firm skin. It’s a good idea to use a vitamin C serum for daytime wear to protect you from the sun, pollution, and other harmful factors that can damage skin.\"\n }\n },\n \"recommended_ingredients\": [\n \"Aloe vera\",\n \"Green tea\",\n \"Vitamin C\",\n \"Niacinamide (Vitamin B3)\",\n \"Hyaluronic Acid\",\n \"Caffeine\",\n \"SPF 30\"\n ],\n \"avoid_ingredients\": [],\n \"GENES\": {\n \"MC1R\": {\n \"rs1805007\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"MC1R@DUB564\": {\n \"rs1805008\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"IRF4\": {\n \"rs12203592\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"TYR\": {\n \"rs1126809\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"RALY\": {\n \"rs6059655\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"OCA2\": {\n \"rs1800407\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"SKIN DRYNESS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"You are less likely to have a skin dryness condition.\",\n \"risk_management\": \"Moisturized, healthy skin begins with a healthy body. Avoid extreme temperatures (both hot and cold) and maintain good hydration throughout the day. External skin moisturizers can improve the quality and appearance of the skin, but staying hydrated by drinking water will improve your skin from the inside and reduce signs of aging. \\n\\nWhile you want to stay hydrated, sweating is also beneficial to your skin. It can flush out impurities (often better than skin cleansers), and it also kills infections and bacteria that can damage your skin. Get a good sweat once a day, either from exercise or sports. A hot sauna is not recommended, as it may cause excess dryness.\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"In this table, different variations resulting in eczema and ichthyosis vulgaris-related skin dryness were assessed, including the skin's response to hydration and its ability to retain moisture.\",\n \"about\": \"Xerosis (dry skin) is characterized by itchy, dry, cracked, and fissured skin. It can be caused by several factors, such as cold and dry climate, frequent bathing, genetics, and other conditions, like eczema. On the other hand, ichthyosis is a collection of inherited skin disorders in which dead skin cells accumulate in thick, dry scales on your skin's surface as a result of moisture escaping the skin. \",\n \"caption\": \"When hydration is most important\",\n \"active_ingredients\": {\n \"Aloe vera\": {\n \"description\": \"Aloe vera is a humectant, which means it binds water to your skin to combat dehydration and maintain moisture. It's also antibacterial, which keeps the skin healthy and breakout-free.\"\n },\n \"Hyaluronic Acid\": {\n \"description\": \"Hyaluronic acid helps hydrate your skin without leaving a greasy film.\"\n },\n \"Niacinamide (Vitamin B3)\": {\n \"description\": \"Niacinamide (Vitamin B3) strengthens your skin’s natural barrier function, which prevents moisture loss, reduces sensitivity, and prevents breakouts; it also has the additional benefits of stimulating collagen production, leaving the skin soft, firm, and elastic.\"\n }\n },\n \"recommended_ingredients\": [\n \"Aloe vera\",\n \"Hyaluronic Acid\",\n \"Niacinamide (Vitamin B3)\",\n \"Green tea\",\n \"Vitamin C\",\n \"Caffeine\",\n \"SPF 30\"\n ],\n \"avoid_ingredients\": [],\n \"GENES\": {\n \"FLG/\\nFLG-AS1\": {\n \"rs61816761\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"FLG@DUB962\": {\n \"rs121909626\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"SSBP3\": {\n \"rs7523947\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"SSBP2\": {\n \"rs454578\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"SKIN OILINESS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"You have a typical likelihood of oily skin condition.\",\n \"risk_management\": \"Although oily skin can block pores and contribute to acne breakouts, oiliness also has several advantages. Oil helps keep the skin moisturized, and individuals with oily skin tend to have thicker skin and fewer wrinkles. The best approach is to find the right balance between having too much oil and preserving the natural moisture of your skin. \\n\\nIn order to determine if your skin is oily, you can employ the three-step blotting test, starting with washing your face with a gentle cleanser and water, then drying your face with a towel, and leaving your skin alone for one hour, without applying any products or touching it. After the hour is up, blot your skin with tissue paper; if there’s oil on your T-zone (forehead, nose, and chin), and on your cheeks, you have oily skin.\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Your environment, lifestyle, and genetics collectively determine your skin's oiliness. This analysis shows the different genes correlated with sebum production particularly, those that are associated with skin conditions including seborrhea, seborrheic keratosis, and seborrheic dermatitis (dandruff).\",\n \"about\": \"\\nThe skin's oiliness is often caused by overproduction of sebum (oil) from the sebaceous glands.\\n\\nSebum is an oily, waxy substance, primarily composed of triglycerides and fatty acids (57%), wax esters (26%), squalene (12%), and cholesterol (4.5%). It coats, moisturizes, and protects your skin. However, excess sebum in the skin eventually leads to heightened oiliness, which can result in clogged pores, dandruff and acne. Genetics, physiological (hormonal) changes, or even stress may increase sebum production.\\n\",\n \"caption\": \"Problematic oil deposits in the skin\",\n \"active_ingredients\": {\n \"Aloe vera\": {\n \"description\": \"Aloe vera is a humectant, which means it binds water to your skin to combat dehydration and maintain moisture. It's also antibacterial, which keeps the skin healthy and breakout-free.\"\n },\n \"Hyaluronic Acid\": {\n \"description\": \"Hyaluronic acid helps hydrate your skin without leaving a greasy film.\"\n },\n \"Niacinamide (Vitamin B3)\": {\n \"description\": \"Niacinamide (Vitamin B3) strengthens your skin’s natural barrier function, which prevents moisture loss, reduces sensitivity, and prevents breakouts; it also has the additional benefits of stimulating collagen production, leaving the skin soft, firm, and elastic.\"\n }\n },\n \"recommended_ingredients\": [\n \"Aloe vera\",\n \"Hyaluronic Acid\",\n \"Niacinamide (Vitamin B3)\",\n \"Green tea\",\n \"Vitamin C\",\n \"Caffeine\",\n \"SPF 30\"\n ],\n \"avoid_ingredients\": [],\n \"GENES\": {\n \"TERT\": {\n \"rs2853676\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"TERT@DUB204\": {\n \"\\trs2853672\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"TERT@DUB589\": {\n \"rs10069690\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n }\n }\n },\n \"skin conditions\": {\n \"goal_result\": \"Intermediate risk\",\n \"goal_result_description\": \"You have a moderate risk for skin diseases, such as acne, rosacea, eczema, and psoriasis. You should consult with your doctor or dermatologist to be improve your skincare and avoid worsening symptoms.\",\n \"TRAITS\": {\n \"ACNE\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your results are associated with an intermediate risk of acne vulgaris. \",\n \"risk_management\": \"Stress, diet, and lifestyle are big risk factors for developing acne. Increased stress, a fatty or oily diet, excess work and fatigue, or a lack of proper skin care can all lead to acne. \\n\\nIf you have oily skin, you should remove sebum more frequently to avoid build-up and bacterial infection. If you have dry skin, you should unclog pores to avoid infections that produce inflamed bumps under the skin. No matter your skin type, cleansing and moisturizing your skin is recommended; moisturized skin is better able to fight the bacterial infections that lead to acne.\\n\\nA dermatologist can examine your skin to identify your unique skin type and present you with specific treatment options for acne that is overwhelming or difficult to manage. Simple, healthy lifestyle changes will often be the best initial treatment. Drinking more water and properly cleaning and moisturizing the skin is imperative. \",\n \"star_rating\": 2,\n \"snp_table_caption\": \"These genes affect the risk of \\\"acne vulgaris\\\" and sebum production in the body. Identifying your genetic risk for acne and the elements behind it can help you develop a lifestyle and skincare routine that will minimize the formation and severity of acne. \",\n \"about\": \"Acne (acne vulgaris) is the most common skin condition and a frequent dilemma among teenagers and young adults, although some older adults are also affected. \\n\\nIt primarily begins in the sebaceous glands. These glands produce sebum, a fatty substance that carries dead cells through the follicles (holes) to the skin's surface. When the follicle is clogged, a pimple is formed, and the bacteria inside the follicle cause swelling.\",\n \"caption\": \"Clogged pores and sebum build-up\",\n \"active_ingredients\": {\n \"Resveratrol\": {\n \"description\": \"Resveratrol is a powerful antioxidant proven to decrease acne bacteria growth in your skin.\"\n },\n \"Salicylic acid\": {\n \"description\": \"Salicylic acid provides gentle exfoliation that can help minimize impactions (clogged pores) by encouraging skin to peel, reducing compacted surface skin cells.\"\n },\n \"Borage seed oil\": {\n \"description\": \"Borage seed oil helps in decreasing sebum production, resulting in fewer breakouts.\"\n }\n },\n \"recommended_ingredients\": [\n \"Resveratrol\",\n \"Salicylic acid\",\n \"Borage seed oil\",\n \"Azelaic acid\",\n \"Kojic acid\",\n \"Jojoba beads\",\n \"Wheat germ oil\",\n \"Grape seed oil\",\n \"Benzoyl peroxide\",\n \"Bisabolol (chamomile)\",\n \"Aloe vera\",\n \"Panthenol\",\n \"Boldine extract\",\n \"Epigallocatechin gallate (green tea)\",\n \"Zinc oxide\",\n \"Milk thistle-derived silybin and caffeine\",\n \"Hyaluronic acid\",\n \"Vitamin B6\",\n \"5-aminolevulinic acid (ALA)\",\n \"Oat\",\n \"Fennel extract\",\n \"Glycerin\",\n \"SPF 30 or higher\"\n ],\n \"avoid_ingredients\": [\n \"Oleic acid\",\n \"Isopropyl esters\",\n \"Surfactants\",\n \"Alcohol\",\n \"Detergents\",\n \"Polyethylene\",\n \"Aluminum oxide\"\n ],\n \"GENES\": {\n \"SELL\": {\n \"rs7531806\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"DDB2\": {\n \"rs747650\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"OVOL1\": {\n \"rs537786\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"FST\": {\n \" rs38055\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"TGFB2\": {\n \" rs1159268\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"LGR6\": {\n \"rs788640\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"BCL11A\": {\n \"rs2110398\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"GLI2\": {\n \"rs10167980\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"WNT10A\\n\": {\n \"rs121908120\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"SUGCT\": {\n \"rs7808121\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"PINX1\": {\n \"rs6601522\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Rosacea\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your result is correlated with an intermediate risk for severe Rosacea.\",\n \"risk_management\": \"There is currently no available medical test for Rosacea. Dermatologists diagnose your condition based on an examination of the skin and eyes. Get sun-protected always and avoid foods, drugs and activities that may trigger the disease.\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Rosacea is an incurable but manageable skin disease. Although it is not life-threatening, untreated Rosacea may lead to permanent facial skin abnormalities that can affect the psychological wellbeing of patients. Genetics plays a big role in the development of the disease. Recently, a large study has identified genetic variants associated with rosacea symptom severity. Here, those genetic variants were used to assess your genetic predisposition risk for Rosacea.\",\n \"about\": \"Rosacea is an incurable but manageable skin disease. Although it is not life-threatening, untreated Rosacea may lead to permanent facial skin abnormalities that can affect the psychological wellbeing of patients. Genetics plays a big role in the development of the disease. Recently, a large study has identified genetic variants associated with rosacea symptom severity. Here, those genetic variants were used to provide genetic insight into underlying disease processes in rosacea as a combination of skin type and susceptibility to inflammation. \",\n \"caption\": \"Red bumps in the skin\",\n \"active_ingredients\": {\n \"Topical antibiotics\": {\n \"description\": \"Several topical antibiotics have been used for the control and improvement of Rosacea symptoms.\"\n },\n \"Sunscreen (Rosacea friendly)\": {\n \"description\": \"Sunscreen is used as protection against UV rays to prevent the worsening of light-sensitive Rosacea.\"\n },\n \"Azelaic acid\": {\n \"description\": \"Azelaic acid is a standard treatment approved by the FDA which has been shown to reduce inflammation of the skin.\"\n }\n },\n \"recommended_ingredients\": [\n \"Topical antibiotics\",\n \"Sunscreen (Rosacea friendly)\",\n \"Azelaic acid\",\n \"Hyaluronic acid\",\n \"Aloe vera\",\n \"Green tea\",\n \"Chamomile\",\n \"Tretinoin\",\n \"Tazarotene\",\n \"Adapalene\",\n \"Permethrin\",\n \"Lindane\"\n ],\n \"avoid_ingredients\": [\n \"Alcohol\",\n \"Camphor\",\n \"Fragrance\",\n \"Glycolic acid\",\n \"Lactic acid\",\n \"Menthol\",\n \"Sodium lauryl sulfate\",\n \"Urea\",\n \"Acetone\",\n \"Corticosteroids\",\n \"Retinoids (sometimes)\",\n \"Cosmetics (sometimes)\"\n ],\n \"GENES\": {\n \"IRF4\": {\n \"rs12203592\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HERC2\": {\n \"rs1129038\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"SLC45A2\": {\n \"rs16891982\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"SNX32\": {\n \"rs10896050\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"MC1R\": {\n \"rs1805007\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"Intergenic (NCR3-AIF1\\n)\": {\n \"rs3132451\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"Intergenic (IER3-DDR1\\n)\": {\n \"rs1264350\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Psoriasis\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"You have a lower risk of contracting psoriasis than most people. \",\n \"risk_management\": \"While you have a lower risk of developing psoriasis, it is strongly advised that you still maintain healthy diet and exercise. Avoid getting stressed and be extra careful when consuming food that may contain allergens which can further increase the likelihood of its development. \\n\\nIf this happens, there are over-the-counter treatments, like topical corticosteroids, that can be applied at least twice a day to relieve dryness, redness, and itching. We recommend keeping your skin hydrated and using moisturizing lotions to prevent the dryness that can worsen psoriasis symptoms.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"This analyzes susceptibility genes that play a major role in psoriasis. This also includes genes implicated in other autoimmune diseases.\",\n \"about\": \"Psoriasis is an immune-mediated disease characterized by raised, red, scaly patches, or \\\"plaques,\\\" appearing on the skin. These plaques are often found on elbows and knees, but they can occur anywhere on the body. This condition is commonly occuring in the adult population.\",\n \"caption\": \"Itchy red patches on the skin.\",\n \"active_ingredients\": {\n \"Aloe vera\": {\n \"description\": \"Studies show that Aloe vera extract can help reduce common symptoms, such as redness and scaling, associated with psoriasis.\"\n },\n \"Apple cider vinegar\": {\n \"description\": \"Apple cider vinegar (naturally sourced) can be used to help relieve the scalp itch from psoriasis.\"\n },\n \"Mahonia aquifolium (Oregon Grape)\": {\n \"description\": \"Mahonia aquifolium (Oregon Grape) is a powerful antimicrobial herb that is effective in treating mild to moderate psoriasis.\"\n }\n },\n \"recommended_ingredients\": [\n \"Aloe vera\",\n \"Apple cider vinegar\",\n \"Mahonia aquifolium (Oregon Grape)\",\n \"Capsaicin\",\n \"Dead sea salts\",\n \"Turmeric\"\n ],\n \"avoid_ingredients\": [\n \"Alcohol\",\n \"Deodorant soaps\",\n \"Laundry soaps\",\n \"Lauryl sulfate\",\n \"Ammonium lauryl sulfate\",\n \"Lithium\",\n \"Propranolol\",\n \"Quinidine\"\n ],\n \"GENES\": {\n \"MHC\": {\n \"rs10484554\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"MHC@DUB67\": {\n \"rs2395029\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"FASLG\": {\n \"rs10798176\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"IKBKE\": {\n \"rs2297545\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"ZNF365\": {\n \"rs4745856\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"KLRK1, KLRC4\": {\n \"rs2900421\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"BRAP, MAPKAPK5\": {\n \"rs3184504\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"FUT2\": {\n \"rs492602\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Eczema\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your result is associated with an intermediate risk of developing eczema.\",\n \"risk_management\": \"Keep your skin hydrated and moisturized all the time. A physical test and review of your medical history by a doctor is the only way to identify atopic dermatitis. A patch test can be done to rule out other skin diseases or allergies. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Studies have suggested several genetic loci associated with predisposition to atopic dermatitis. This includes variants of the FLG gene which has been suggested as the strongest risk contributor that results to epidermal barrier deficiency.\",\n \"about\": \"Atopic dermatitis (eczema) is a chronic skin condition that makes your skin red and itchy. It is an inflammation that can have numerous triggers, and it can be made worse by environmental factors. \\n\\nEczema is long-lasting (chronic) and tends to flare up periodically. Sometimes, it may be accompanied by asthma or hay fever. It's common in children and infants, but can occur at any age.\",\n \"caption\": \"Red, itchy skin.\",\n \"active_ingredients\": {\n \"Moisturizers\": {\n \"description\": \"The regular use of moisturizer is the best way to keep the skin hydrated at all times.\"\n },\n \"Shea butter\": {\n \"description\": \"Shea butter acts as a moisturizer that can prevent skin dryness and lock in your skin's natural oils.\"\n },\n \"Green tea\": {\n \"description\": \"Green tea has several active properties that can reduce the inflammation and itchiness of sensitive and dry skin.\"\n }\n },\n \"recommended_ingredients\": [\n \"Moisturizers\",\n \"Shea butter\",\n \"Green tea\",\n \"Chamomile\",\n \"Hyaluronic acid\"\n ],\n \"avoid_ingredients\": [\n \"Alpha hydroxy acids\",\n \"Beta hydroxy acids\",\n \"Sulfates\",\n \"Retinol\",\n \"Fragrances\",\n \"Parabens\",\n \"Phthalates\"\n ],\n \"GENES\": {\n \"RTEL1-TNFRSF6B\": {\n \"rs6010620\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"CLEC16A\": {\n \"rs2041733\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"ADAMTS10/ACTL9\": {\n \"rs2164983\": {\n \"genotype\": \"CA\",\n \"effect_allels\": 1\n }\n }\n }\n }\n }\n },\n \"skin photoaging\": {\n \"goal_result\": \"Good\",\n \"goal_result_description\": \"Your skin is less likely to age or develop freckles and visible damage as a result of UV radiation exposure. In order to keep your skin looking young and refreshed, avoid excess sun exposure, use sunscreen, moisturize your skin, and avoid unhealthy foods, such as sugar, which can increase skin damage at the cellular level. \",\n \"TRAITS\": {\n \"SKIN PIGMENTATION\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your genes are associated with average risk of skin pigmentation.\",\n \"risk_management\": \"Skin tone is not a health risk on its own, but constant sun exposure may lead to an increased risk of cancer. It is best to always wear sunscreen of at least SPF 30 to avoid the detrimental effects of UV radiation.\\n\\nSkin pigmentation is determined by Wood's Lamp Examination; it involves lighting at a specific spectrum of light in a dark room to determine abnormal pigmentation caused by different bacteria. Healthy skin should produce no visible glow, while its skin pigmentation (based on melanocytes) is determined based on skin-tone pallets.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"The genes in this table reflect your production (biosynthesis) of melanin and light reception. However, the use of sunscreen, and certain disease may affect your production of melanin. These genes do not determine your skin color, but rather, your skin's evenness and likelihood of darkening in response to sunlight.\",\n \"about\": \"Pigmentation is coloring. Your skin is colored by a pigment called melanin. Special skin cells make melanin, which help protect your skin from sun damage.\\n\\nMelanin helps protect your skin by absorbing harmful UV rays when exposed to the sun. This exposure to sunlight may also cause your skin to produce more melanin to protect your skin. As the production of melanin increases, our skin begins to tan and darken. However, it is also possible for melanin production to increase or decrease in response to some diseases, and this may lead to uneven skin tone.\",\n \"caption\": \"Skin's \\\"evenness\\\"\",\n \"active_ingredients\": {\n \"Vitamin C\": {\n \"description\": \"Vitamin C brightens skin and stimulates collagen production for radiant, firm skin. It’s a good idea to use a vitamin C serum for daytime wear to protect the skin from the sun, pollution, and other harmful factors that can harm or damage your skin.\"\n },\n \"SPF 30\": {\n \"description\": \"Sun protection of at least SPF 30 is enough to save your skin from the damaging effects of the sun's UV rays, such as excessive and uneven skin pigmentation.\"\n },\n \"Hyaluronic Acid\": {\n \"description\": \"Hyaluronic acid not only moisturizes your skin but also has antioxidant properties to protect your skin from sun exposure.\"\n }\n },\n \"recommended_ingredients\": [\n \"Vitamin C\",\n \"SPF 30\",\n \"Hyaluronic Acid\",\n \"Niacinamide (Vitamin B3)\",\n \"Green tea\",\n \"Aloe vera\",\n \"Caffeine\"\n ],\n \"avoid_ingredients\": [],\n \"GENES\": {\n \"PPARG/\\nC1B\": {\n \"rs251468\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"RAB11/\\nFIP2\": {\n \"rs12250372\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"IRF4\": {\n \"rs12203592\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"SPATA33\": {\n \"rs35063026\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"SLC45A2\": {\n \"rs16891982\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"TYR\": {\n \"rs1042602\": {\n \"genotype\": \"CA\",\n \"effect_allels\": 1\n }\n },\n \"HERC2\": {\n \"rs1667394\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Sun sensitivity\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your result is correlated with an intermediate risk of being sun sensitive, which means you have average likelihood of experiencing sunburn.\",\n \"risk_management\": \"Every person has a different response to the UV rays of the sun. Always use sunscreen products and protective clothing, regardless of skin tone. Use moisturizers for dry and burned skin. Avoid frequent and excessing tanning practices such as sun bathing. Ask your dermatologists for further recommendations.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Traits related to sun exposure such as tanning ability and sunburn are highly heritable. Large-scale association studies have identified multiple genetic variants responsible for sun sensitivity located in pigmentation-related genes such as MC1R, IRF4, and MATP.\\n\",\n \"about\": \"Sun sensitivity is your skin's response to sun exposure and UV radiation. Exposure to the sun causes various changes to combat the harmful effects of UV radiation. Differences in sensitivity can have different implications for skin health. \\n\\nSun-sensitive individuals (poor tanning response) have a higher risk of sunburn, sunspots, and even skin cancer, while those who tan easily may be prone to Vitamin D deficiency. \",\n \"caption\": \"Sunshine and lotion.\",\n \"active_ingredients\": {\n \"SPF30+ sunscreen\": {\n \"description\": \"SPF sunscreen protects you from sunburns. Sunburn protection factor (SPF) is an indication of the degree of UVA protection.\"\n },\n \"EGCG (Green Tea Extract)\": {\n \"description\": \"EGCG from green tea extract is a polyphenol (micronutrient) that has been shown to protect against UV-induced skin damage.\"\n },\n \"Bemotrizinol\": {\n \"description\": \"Bemotrizinol is an organic compound added to sunscreens which acts as a broad spectrum UV filter.\"\n }\n },\n \"recommended_ingredients\": [\n \"SPF30+ sunscreen\",\n \"EGCG (Green Tea Extract)\",\n \"Bemotrizinol\",\n \"Bisoctrizole\",\n \"Allantoin\",\n \"Vitamin C\",\n \"Aloe vera\",\n \"Soy extract\",\n \"Ferulic acid\",\n \"Resveratrol\"\n ],\n \"avoid_ingredients\": [\n \"Petroleum\",\n \"Benzocaine\",\n \"Lidocaine\"\n ],\n \"GENES\": {\n \"EXOC2\": {\n \"rs12210050\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"TYR\": {\n \"rs1393350\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"IRF4\": {\n \"rs12203592\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"LOC401937\": {\n \"rs966321\": {\n \"genotype\": \"GT\",\n \"effect_allels\": 1\n }\n },\n \"MC1R\": {\n \"rs352935\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"MC1R@DUB183\": {\n \"rs464349\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"MATP\": {\n \"rs35406\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"chr14:96637470\": {\n \"rs17094273\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Skin Aging\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your result is correlated with a low risk of premature skin aging\",\n \"risk_management\": \"Reduce your sun exposure, and use sunscreen when outside for extended periods, even on cloudy days. Maintain a proper diet and drink plenty of water. Use antioxidants for skin health. Use skin products that prevent the visible signs of aging.\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Genetic variants, such as alleles found in the IRF4, MC1R, SLC45A2, BNC2 and RALY genes, are associated with risks related to skin aging phenotypes. These heritable factors, influenced by external factors such as UV radiation, have implications on personal skin appearance.\",\n \"about\": \"Skin aging refers to the progressive changes in the appearance and quality of skin that results from a combination of external and internal factors. The skin aging phenotype is a complex set of traits that includes photoaging, age spots, wrinkles, sagging, rough-textured appearance, and a loss of fine skin patterns. UV radiation exposure is the major external factor that influences these phenotypes, which leads to cumulative structural and physiological alterations in skin appearance.\",\n \"caption\": \"Premature skin aging\",\n \"active_ingredients\": {\n \"SPF sunscreen\": {\n \"description\": \"SPF sunscreen protects you from the effects of sun-caused aging. Sunburn protection factor (SPF) is an indication of the amount of UVA protection.\"\n },\n \"Resveratrol\": {\n \"description\": \"Resveratrol is an organic compound that has antioxidant properties, fighting the damage caused by free radicals and UV radiation.\"\n },\n \"Soybean extract\": {\n \"description\": \"Isoflavones from soybean extract improve the visibles signs of skin photoaging. Most importantly, it's an antioxidant that can prevent skin damage from prolonged sun exposure.\"\n }\n },\n \"recommended_ingredients\": [\n \"SPF sunscreen\",\n \"Resveratrol\",\n \"Soybean extract\",\n \"Moisturizers\",\n \"Kojic Acid\",\n \"Vitamin C\",\n \"Green tea extract\",\n \"Licorice extract\",\n \"CoQ10\"\n ],\n \"avoid_ingredients\": [],\n \"GENES\": {\n \"IRF4\": {\n \"rs12203592\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"MC1R\": {\n \"rs1805007\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"MC1R@DUB983\": {\n \"rs1805008\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"RALY\": {\n \"rs6059655\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PPARGC1B\": {\n \"rs251468\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"RAB11FIP2\": {\n \"rs12250372\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"FRECKLES\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your result is correlated with a low likelihood of developing freckles.\",\n \"risk_management\": \"Freckle formation is triggered by sunlight exposure. UVB radiation exposure activates melanocytes to increase the production of melanin, which can result in darker and more visible freckles. \\n\\nFreckles are not dangerous or harmful on their own, but they may indicate excess sun exposure, which can lead to cancer and skin degeneration, so using sunscreen (SPF 30+) is important, and the appearance of new freckles is a warning sign for changes in the skin. Speak with your dermatologist if new freckles develop, especially after childhood. \\n\\nTreatments for lightening or eliminating freckles, such as laser therapy and chemical peels, are also available. Products that contain trichloroacetic acid, phenol, retinoid, alpha hydroxy acids, among others are also used to lighten freckles.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Freckle formation is a recessive genetic trait caused by a series of variations commonly found in the \\\"melanocortin 1 receptor\\\" (MC1R) gene; however, recent studies have uncovered the several genes that may influence the skin's natural production of freckles. Today, freckles are considered \\\"adorable\\\" or even \\\"fashionable.\\\"\\n\\nAssessing your genetic predisposition to freckles is very important since it is associated with several skin pigmentation disorders, such as dyschromatosis symmetrica hereditaria, xeroderma pigmentosum, and cutaneous malignant melanoma.\",\n \"about\": \"Freckles are several pigmented dots commonly found in the Caucasian and Chinese population. They are confined mainly to the face, including the arms and back. \\n\\nFreckles first begin developing on light-exposed skin at about 5 years of age, appearing as light-brown pigmented macules (spots). At the cellular level, freckles show when there is an increased production of melanin pigment, as evidenced by elevated number of melanocytes. \\n\\nFreckles usually stop spreading before adolescence and last for life.\",\n \"caption\": \"Loveable little dots\",\n \"active_ingredients\": {\n \"Sunscreen\": {\n \"description\": \"SPF sunscreen lets you avoid dark spots caused by sunlight. It doesn't get rid of existing freckles, but it helps to prevent the darkening of old spots and the appearance of new ones.\"\n },\n \"Kojic acid\": {\n \"description\": \"Kojic acid is a tyrosinase inhibitor which prevents melanin synthesis. By preventing melanin biosynthesis, the formation of dark pigmented spots is avoided.\"\n },\n \"Licorice extracts\": {\n \"description\": \"Licorice extracts have active components that suppress new melanin creation. It's a popular plant extract for reducing hyperpigmentation.\"\n }\n },\n \"recommended_ingredients\": [\n \"Sunscreen\",\n \"Kojic acid\",\n \"Licorice extracts\",\n \"Vitamin C\",\n \"Hydroquinone\",\n \"Tretinoin\",\n \"Soy extract\"\n ],\n \"avoid_ingredients\": [],\n \"GENES\": {\n \"IRF4/EXOC2\": {\n \"rs1540771\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"IRF4\": {\n \"rs872071\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"IRF4@DUB149\": {\n \"rs12203592\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"TYR\": {\n \"rs1042602\": {\n \"genotype\": \"CA\",\n \"effect_allels\": 1\n }\n },\n \"MC1R\": {\n \"rs1805008\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"MC1R@DUB689\": {\n \"rs1805007\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"ASIP\": {\n \"rs4911414\": {\n \"genotype\": \"TG\",\n \"effect_allels\": 1\n }\n },\n \"ASIP@DUB667\": {\n \"rs619865\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n }\n }\n },\n \"skin texture and elasticity\": {\n \"goal_result\": \"Intermediate\",\n \"goal_result_description\": \"Congrats! You're slightly less likely to develop wrinkles and rapid aging. However, loss of skin texture and elasticity can happen to anyone. Keep your skin tight and young with gentle moisturizers. Stay hydrated with plenty of water throughout the day; good skin starts from the inside! \",\n \"TRAITS\": {\n \"SKIN ELASTICITY AND INTEGRITY\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your genetic test results are correlated with having normal skin elasticity and integrity.\",\n \"risk_management\": \"Skin elasticity is highly dependent on a person's metabolism. To avoid early degradation of the skin, consume a diet rich in vitamins, especially Vitamins C, D, and E. Caring for skin and avoiding wounds will also help in maintaining the skin's integrity and keep the skin elastic. \\n\\nSkin elasticity is a rather inexact science, since it is highly variable based on genetics, age, and weight fluctuations in the body. Your collagen and vitamin levels can be measured by a dermatologist, but caring for the skin and avoiding damage from the sun, toxic chemicals, tobacco, alcohol, and stress can help.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Skin elasticity is highly dependent on the elastin and collagen formation which serves as the backbone of skin integrity. The tightness and elasticity of the skin is therefore dependent on the genes regulating the metabolism of these proteins. This table shows the variants of genes responsible for skin elasticity, integrity, and firmness.\",\n \"about\": \"One of the most common signs of aging is the loss of elasticity of the skin. This is because our body does not produce enough elastin and collagen. \\n\\nElastin is a protein that is responsible for the elastic integrity of the skin. This protein can mostly be found in the middle layer of the dermis and is the dominant protein present in the lungs, aorta, and skin. Not only does it give elasticity to our skin, but it also helps our blood vessels, tendons, heart, lungs, and other major organs remain flexible. \\n\\nCollagen, on the other hand, is rigid. Elastin is 1,000 times more flexible than collagen. Together, they make your skin firm, yet flexible.\\n\\nCollagen is the most abundant protein in our body, accounting for almost 30% of our body's total protein content. Collagen is a set of proteins found in our fibrous connective tissues, usually in the lower layers of the dermis. For these connective tissues, collagen proteins are accountable for being a sort of cellular adhesive, which keeps their shape and makes them rigid and strong.\",\n \"caption\": \"Does your skin \\\"bounce back\\\"?\",\n \"active_ingredients\": {\n \"Niacinamide (Vitamin B3)\": {\n \"description\": \"Niacinamide (Vitamin B3) strengthens your skin’s natural barrier function, which prevents moisture loss, sensitivity, and breakouts; it has the additional benefit of stimulating collagen production, leaving the skin soft, firm, and elastic.\"\n },\n \"Green tea\": {\n \"description\": \"Green tea is packed with powerful antioxidants, which prevent fine lines, age spots, and the breakdown of collagen.\"\n },\n \"Vitamin C\": {\n \"description\": \"Vitamin C brightens skin and stimulates collagen production for radiant, firm skin. It’s a good idea to use a vitamin C serum for daytime wear to protect the skin from the sun, pollution, and other harmful factors that can damage skin.\"\n }\n },\n \"recommended_ingredients\": [\n \"Niacinamide (Vitamin B3)\",\n \"Green tea\",\n \"Vitamin C\",\n \"Hyaluronic Acid\",\n \"Aloe vera\",\n \"Caffeine\",\n \"SPF 30\"\n ],\n \"avoid_ingredients\": [],\n \"GENES\": {\n \"MC1R\": {\n \"rs1805005\": {\n \"genotype\": \"GT\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"STRETCH MARKS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your genetic profile is associated with an intermediate likelihood of developing stretch marks.\",\n \"risk_management\": \"Maintaining a healthy weight is the best way to reduce the likelihood of getting stretch marks. Work with your doctor by eating well and exercising to avoid gaining too much weight at one time. Not only does this minimize stretch marks, but it also makes you and your baby healthy. \\n\\nIt's debatable whether stretch marks can be prevented by using topical ointments and oils. Laser and light device treatments improve the appearance of stretch marks. Microneedling has also been used, as well as non-ablative and fractionated lasers. Topical applications of moisturizers containing Centella asiatica triterpenes and vitamin E may reduce the severity of stretch marks in pregnant women.\\n\\nIn some studies, non-invasive multipolar-pulsed electromagnetic field and energy-generating radiofrequency treatment led to some improvement in stretch mark length and width. Generally speaking, early stretch marks respond better to treatment than older lesions, so treating stretch marks quickly is important in minimizing their appearance.\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Reduced expression of collagen, elastin, and fibronectin is suggestively associated with the development of stretch marks. Here, variants responsible for the expression of these elastic microfibrils were used to assess your genetic predisposition for stretch marks. \",\n \"about\": \"Stretch marks or striae distensae (syn. striae gravidarum) are common streaks that appear initially as red, and later on, white, lines on the skin, and are commonly caused by pregnancy, affecting approximately 50–90 percent of pregnant women. These lines represent scars of the dermis, and are characterized by lines of collagen lying parallel to the surface of the skin, as well as eventual loss of collagen and elastin. These are commonly seen on the thighs, abdomen, and breasts of females, as well as the upper arms of males. \\n\\nStretch marks are also seen in other conditions, such as rapid weight gain (obesity), muscle hypertrophy (growth), endocrinopathy (such as Cushing's syndrome), breast augmentation, or as a side effect of the topical use and abuse of corticosteroids. \",\n \"caption\": \"Streaks of thin, glossy, red skin\",\n \"active_ingredients\": {\n \"Tretinoin\": {\n \"description\": \"Tretinoin is a vitamin A derivative that has been shown to improve the appearance of stretch marks during their early presentation.\"\n },\n \"Centella asiatica\": {\n \"description\": \"Centella asiatica (CA) contains asiaticoside that is reported to stimulate type I collagen synthesis. Creams with CA have been found to decrease stretch marks, particularly during pregnancy.\"\n },\n \"Vitamin E\": {\n \"description\": \"Vitamin E has been shown to reduce stretch marks by supporting cell growth and regeneration. Combining this vitamin with other skincare ingredients has rejuvenating benefits.\"\n }\n },\n \"recommended_ingredients\": [\n \"Tretinoin\",\n \"Centella asiatica\",\n \"Vitamin E\",\n \"Hyaluronic acid\",\n \"Almond oil\"\n ],\n \"avoid_ingredients\": [],\n \"GENES\": {\n \"ELN\": {\n \"rs7787362\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"TMEM18\": {\n \"rs10189761\": {\n \"genotype\": \"AT\",\n \"effect_allels\": 1\n }\n },\n \"FN1\": {\n \"rs1250229\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"NPIPL2\": {\n \"rs4788073\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"FACIAL WRINKLES\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Your result is correlated with a high likelihood of developing premature wrinkles\",\n \"risk_management\": \"Avoid frequent and long exposure to sunlight without protection. Always use SPF sunscreen products and protective gear (such as hats or parasols). Make sure to keep the skin hydrated at all times. Limit smoking and alcohol consumption as much as possible. If wrinkles have already developed, talk to your dermatologist for skin tightening recommendations.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Individuals with genetic variants in the STXBP5L, FBX040 and IRF4 genes are likely to develop severe wrinkles.\",\n \"about\": \"Wrinkles are one of the signs of skin aging and become visible as a result of several factors such as genetics, lifestyle, sun damage, smoking, alcohol abuse, and time. Although genetics and the passage of time greatly influence the formation of wrinkles, other factors, particularly UV exposure, increase wrinkling. Wrinkles appear as lines and furrows in the skin and occur when the elastin and collagen fibers break down and disappear.\",\n \"caption\": \"Lines and Furrows\",\n \"active_ingredients\": {\n \"Hyaluronic acid\": {\n \"description\": \"Hyaluronic acid is a widely used cosmetic ingredient that maintains skin's elasticity and moisture. It revitalizes the skin to reduce the appearance of wrinkles.\"\n },\n \"Collagen-building peptides\": {\n \"description\": \"Collagen-building peptides are important to increase collagen levels in your skin. It improves elasticity and reduces signs of fine lines and wrinkles.\"\n },\n \"CoQ10\": {\n \"description\": \"A clinical study showed that topical application of CoQ10 leads to an improvement in wrinkled skin by reducing ROS, which degrades the dermal skin.\"\n }\n },\n \"recommended_ingredients\": [\n \"Hyaluronic acid\",\n \"Collagen-building peptides\",\n \"CoQ10\",\n \"SPF sunscreen\",\n \"Vitamin C\",\n \"Vitamin E\",\n \"Alpha-lipoic acid\",\n \"Green tea extract\",\n \"Soy extract\",\n \"Resveratrol\",\n \"Tartaric acid\",\n \"Malic acid\",\n \"Citric acid\",\n \"Mandelic acid\"\n ],\n \"avoid_ingredients\": [],\n \"GENES\": {\n \"STXBP5L\": {\n \"rs17740066\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"FBXO40\": {\n \"rs6775899\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"IRF4\": {\n \"rs12203592\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n }\n }\n }\n }\n }\n }\n}"},{"id":"44421fcb-89ef-467f-8731-6c75f7c8455b","name":"Skincare Report Customer Not Found Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1c2b7b12b289_709f9fd16bb5_8aafce768660\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/skincare/report"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; 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Description: This Endpoint generates/retrieves the latest immunity and vitamins report for any customer

Request Parameters:

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Parameter	Required/Optional	Type
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Response Parameters:

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Parameter

Type

Note

status

int

200 For Success

4xx for errors

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String

report_json

JSON

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You will probably need additional support during the cold season. Regular exercise and plenty of sleep can also reduce the length and frequency of illnesses. \",\n \"TRAITS\": {\n \"VITAMIN C LEVELS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Based on your genetic analysis, your result is correlated with intermediate Vitamin C levels.\",\n \"risk_management\": \"Vitamin C cannot be synthesized by the human body; therefore, getting enough through diet and supplementation is important. Make sure to eat foods enriched with ascorbic acid, such as fruits and vegetables. Take Vitamin C supplements as needed. \",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Several genes are involved in creating molecules that transport Vitamin C. These molecules are called sodium L-ascorbic acid cotransporters (SVCTs). Genome wide association studies show that variants of these genes are associated with Vitamin C levels in the blood, and indicate your potential risk for infection and disease.\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\",\n \"about\": \"The body's ability to defend itself from disease-causing pathogens, such as bacteria and viruses, is directly related to one's level of immune response. Boosting your immunity can be achieved by enhancing levels of certain essential micronutrients, including ascorbic acid, also known as Vitamin C. The level of Vitamin C in the body can reduce your risk of contracting potentially fatal infections and diseases.\",\n \"caption\": \"Immune system booster\",\n \"ingredients\": {\n \"Vitamin C\": {\n \"dosage\": \"90 mg\",\n \"description\": \"Vitamin C is a water-soluble antioxidant that supports your immune defense by enhancing various cellular functions. It is involved in epithelial barriers, phagocytosis (a cell's ability to consume particles), antibody levels, and your inflammatory response. \"\n },\n \" Citrus Bioflavonoids\": {\n \"dosage\": \" 250 mg\",\n \"description\": \"\\nCitrus bioflavonoid works together with Vitamin C to help immunity and has been shown to improve Vitamin C absorption.\"\n }\n },\n \"GENES\": {\n \"SLC23A2\": {\n \" rs1279683\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"COMT/\\nMIR476\\n\": {\n \"rs4680\\n\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"VITAMIN E LEVELS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Based on your genetic analysis, your result is correlated with low Vitamin E levels.\",\n \"risk_management\": \"Vitamin E supplementation is an effective treatment for low Vitamin E levels. The vitamin cannot be produced by the body, so make sure to obtain it through supplementation and diet. Consume foods that are rich in vitamin E, such as nuts, whole grains, vegetables, and eggs. Vitamin E deficiency is a rare condition and is often caused by an underlying condition that affects the absorption of fat. Consult your doctor if you experience any symptoms of Vitamin E deficiency, or if you have a history in the family.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Various genes, including CYP4F2, SCARB1 ZPR1, and their variants, impact the level and efficacy of vitamin E the body. The level of vitamin E present in the body is associated with your immune response because it helps the immune system generate more antibodies in response to infection. \",\n \"about\": \"Immunity is simply how effective the body is in defending itself from foreign substances and pathogenic microorganisms that cause diseases. Vitamin E, in the form of alpha-tocopherol, is an essential nutrient that promotes better immunity by stimulating the production of immune cells that specifically fight pathogens.\",\n \"caption\": \"More immune cells\",\n \"ingredients\": {\n \"Vitamin E\": {\n \"dosage\": \"27 mg (30 IU)\",\n \"description\": \"Vitamin E (dl-alpha-tocopherol) is the major fat-soluble antioxidant for boosting the immune system and fighting harmful microorganisms. Studies show that vitamin E supplementation results in increased lymphocytes (white blood cells), which are crucial to your immune response.\"\n }\n },\n \"GENES\": {\n \"CYP4F2\": {\n \"rs2108622\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"ZPR1\": {\n \"rs964184\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"APOA5\": {\n \"rs12272004\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"ZINC LEVELS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Based on your genetic analysis, your result is correlated with high zinc levels.\",\n \"risk_management\": \"Zinc can be easily obtained and replenished through diet and/or supplementation. A wide number of foods can provide a natural source of zinc, including animal meat, poultry, whole grains, beans, and nuts. Zinc supplements should be taken with food, as it can irritate the mouth and stomach. Consume only the recommended dosage of zinc, unless your doctor suggests otherwise. Checking the definite zinc levels in your body is not simple and requires a lot of testing. Consult with your physician as needed.\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"The amount of zinc in the body can be affected by several genes. Variants in these genes have been associated with the expression of zinc-containing enzymes, as well as enzymes involved in zinc metabolism. \",\n \"about\": \"Zinc is an essential mineral used by processes involving enzymes and the immune system. Its bioavailability depends on the daily intake through diet and daily loss by excretion, which are influenced by several factors such as age, life stages, and diet composition.\",\n \"caption\": \"A powerful mineral\",\n \"ingredients\": {\n \"Zinc\": {\n \"dosage\": \"9.4 mg\",\n \"description\": \"Zinc is an integral component in the regulation of healthy immune cells, thus boosting overall immune functions and wound healing. It affects the development and function of white blood cells, including neutrophils, NK cells, macrophages, and T & B cells that are involved in your innate immunity and your ability to fight new infections.\"\n }\n },\n \"GENES\": {\n \"CA1\": {\n \"rs1532423\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"PPCDC\": {\n \"rs2120019\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"NBDY\": {\n \"rs4826508\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n }\n }\n }\n }\n },\n \"cardiovascular health\": {\n \"goal_result\": \"WEAK\",\n \"goal_result_description\": \"Iron, copper and cholesterol both work together to influence your cardiovascular health in different ways. Your body has difficulty managing iron and maintaining healthy cholesterol levels. Stress, lack of exercise, poor sleep, and an unhealthy diet may all increase your risk of cardiovascular disease even further. Remember: you are in control of your body and your health! Maintain a good workout routine and a smart diet with the right supplements to keep your body healthy.\",\n \"TRAITS\": {\n \"IRON LEVELS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Based on your genetic analysis, your result is correlated with low iron levels.\",\n \"risk_management\": \"Maintain healthy levels of iron by consuming foods such as red meat, dark green and leafy vegetables, and iron-fortified foods to avoid iron deficiency. Intake of vitamin C will help the body absorb iron better. Iron supplements are also an alternative for improving iron levels in the body. However, consume only the recommended dosage of iron, unless your health care provider suggests otherwise. Avoiding foods that can inhibit iron absorption, such as tea, coffee, and foods rich in calcium, may also be beneficial. Iron in the form of ferric citrate and ferric EDTA must be avoided because these forms may cause cancer, according to studies. Consult with your physician if you suspect that you have an iron-deficiency related disease. A simple blood test will reveal if the iron levels in your blood are deficient or elevated.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"This table shows the genes that are associated with iron levels in your blood. Genes such as TF, HFE, TFR2, and TMPRSS6 affect the variation in levels of known biomarkers for iron balance, such as serum iron, total binding capacity, \\\"transferrin saturation,\\\" and ferritin. These genes are also commonly associated with blood-related diseases, such as anemia and hemochromatosis.\",\n \"about\": \"Iron is an essential bioelement that helps regulate cardiovascular vascular health and function. Balancing your iron levels (iron homeostasis) is critically important, because certain diseases are more likely with iron deficiencies, and toxicity can quickly occur with excess iron. \",\n \"caption\": \"Anemia and toxicity\",\n \"ingredients\": {\n \"Ferrous salts\": {\n \"dosage\": \"40 mg\",\n \"description\": \"Iron is an essential mineral that is found mostly in red blood cells and muscle cells. It helps deliver oxygen from the lungs to the tissues and helps store oxygen in the muscles. Carbonyl iron is also an alternative form of ferrous salts. \"\n },\n \" Vitamin C\": {\n \"dosage\": \" 500 mg\",\n \"description\": \"\\nTaking Vitamin C has been shown to improve iron absorption. It captures and stores iron in a form that is more easily absorbed, thus increasing iron bioavailability.\"\n }\n },\n \"GENES\": {\n \"HFE\": {\n \"rs1799945\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"TMPRSS6\": {\n \"rs855791\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"HFE@DUB513\": {\n \"rs1800562\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"TF\": {\n \"rs8177240\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"TFR2\": {\n \"rs7385804\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Cholesterol levels\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Based on your genetic analysis, your result is correlated with high LDL levels.\",\n \"risk_management\": \"Lower LDL and higher high-density lipoprotein (HDL) are ideal. LDL is still needed by the body, so be sure not to reduce these levels too far. Eat a more healthy diet by limiting the amount of fat intake. Include exercise in your lifestyle. Having high levels of LDL is usually asymptomatic until a heart attack or stroke happens. The only way to determine cholesterol levels is through a blood test. Consult your doctor for the ideal LDL: HDL ratio.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Many of these genes regulate lipid metabolism and transport, which are correlated with varying levels of cholesterol and triglycerides in the blood. This table shows the genes that are associated with levels of LDL in the blood.\",\n \"about\": \"Cholesterol is a known risk factor for cardiovascular diseases. High levels of low-density lipoprotein (LDL), also known as the \\\"bad cholesterol,\\\" is linked to an increased likelihood of heart attack and stroke, as LDL often builds up as plaque that clogs the arteries.\",\n \"caption\": \"The good and the bad\",\n \"ingredients\": {\n \"Vitamin B3\": {\n \"dosage\": \"20 mg\",\n \"description\": \"Vitamin B3 (niacin) is a water-soluble vitamin that has been used to regulate plasma lipoproteins (cholesterol) and treat atherosclerosis. It is a common supplement for reducing LDL levels and boost the amount of HDL. \"\n },\n \" Garlic\": {\n \"dosage\": \" 1000 mg\",\n \"description\": \"\\nLong-term supplementation of garlic has been shown to reduce the total cholesterol and low-density lipoprotein levels (LDL) in individuals with high cholesterol. \"\n },\n \" Turmeric \": {\n \"dosage\": \" 500 mg (twice daily)\",\n \"description\": \"\\nCurcumin is the active component found in turmeric, which has cholesterol-lowering effects in people with high cholesterol. \"\n }\n },\n \"GENES\": {\n \"CELSR2\": {\n \"rs660240\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"APOB\": {\n \"rs10199768\": {\n \"genotype\": \"TG\",\n \"effect_allels\": 1\n }\n },\n \"TOMM40-APOE\": {\n \"rs2075650\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"APOB@DUB901\": {\n \"rs693\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"APOE-C1-C4-C2\": {\n \"rs4420638\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"HMGCR\": {\n \"rs12654264\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"LDLR\": {\n \"rs6511720\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PCSK9\": {\n \"rs11591147\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"ABO\": {\n \"rs635634\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HNF1A\": {\n \"rs1183910\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"ABCG8\": {\n \"rs11887534\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"HMGCR@DUB600\": {\n \"rs3846662\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"LDLR@DUB564\": {\n \"rs2228671\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Copper levels\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your result is correlated with low copper levels.\",\n \"risk_management\": null,\n \"star_rating\": 2,\n \"snp_table_caption\": \"Even though copper deficiencies are quite rare, examining your genetic risks may help you avoid aggravating certain diseases. This SNP table shows genetic variants associated with copper concentrations in your red blood cells.\",\n \"about\": \"Copper is an essential trace element that is involved in cardiovascular homeostasis. The importance of copper in humans is clearly shown by various conditions involving copper deficiencies, such as anemia, leukopenia, and myeloneuropathy (damage to the spinal cord and peripheral nerves). Sufficient copper levels help maintain the proper structure and function of blood cells in your body.\",\n \"caption\": \"Nerves, immune system, and bones.\",\n \"ingredients\": {\n \"Copper\": {\n \"dosage\": \"5 mg\",\n \"description\": \"Copper is involved in iron absorption and metabolism, as well as the maintenance of blood vessels, nerves, and your immune system. Together with iron, copper helps in the formation of the red blood cells that carry oxygen throughout your body.\"\n }\n },\n \"GENES\": {\n \"SMIM1\": {\n \"rs1175549\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n },\n \"SELENBP1\": {\n \"rs2769264\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n }\n }\n },\n \"liver health\": {\n \"goal_result\": \"STRONG\",\n \"goal_result_description\": \"Liver enzymes are important for breaking down food and removing poisons from your body. However, too much of these enzymes can also lead to swelling of the liver, abdominal pain, dark urine, and other side effects. According to your genetics, you have good liver health, but refraining from alcohol, avoiding drugs, and maintaining a good diet are critical to your liver's long-term health. \",\n \"TRAITS\": {\n \"LIVER ENZYME LEVELS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Based on your genetic analysis, your result is correlated with low liver enzyme levels.\",\n \"risk_management\": \"You can determine your liver enzymes levels by undergoing a few laboratory tests. If enzyme levels are within the normal range, maintain a healthy lifestyle by not smoking, eating healthy foods, and drinking alcohol only in moderation, or abstaining from alcohol entirely. Exercise may also be done to maintain good liver health and overall physical health. Taking supplements rich in silymarin, a compound that helps maintain a healthy liver, is also recommended.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Different genes have been associated with the production of liver enzymes and their overall levels. Certain variations in the genes influencing liver enzymes, including HSD17B13, TRIB1, PNPLA3, and CPN1, have been associated with an increased risk of elevated levels of these enzymes.\",\n \"about\": \"Liver enzymes perform many important metabolic functions crucial for maintaining a healthy body. These enzymes break down food to simpler materials and help in the removal of potentially poisonous byproducts from medications. Liver enzymes, including alanine transaminase (ALT), aspartate transaminase (AST), and gamma-glutamyl transpeptidase (GGT), need to be maintained at a low level, as elevated enzymes could indicate liver problems that may eventually lead to a series of diseases.\",\n \"caption\": \"Breaking down food and toxins\",\n \"ingredients\": {\n \"Milk thistle\": {\n \"dosage\": \"140 mg\",\n \"description\": \"Silymarin is the active component of Silybum marianum (milk thistle). It is a well researched chemical for treating liver disease. It has antioxidant and anti-inflammatory properties that have been used to manage the symptoms of chronic liver diseases caused by oxidative stress (in alcoholic and non-alcoholic fatty liver disease, as well as hepatotoxicity). \"\n },\n \" Artichoke\": {\n \"dosage\": \" 320 mg\",\n \"description\": \"\\nStudies show that artichoke has antioxidant and liver-protecting properties in patients with non-alcoholic liver disease, resulting in a reduction in the serum levels of liver disease biomarkers.\"\n }\n },\n \"GENES\": {\n \"CPN1\": {\n \"rs4919418\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n },\n \"PNPLA3\": {\n \"rs738409\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"RSG1, EPHA2\": {\n \"rs1497406\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"CEPT1, DENND2D\": {\n \"rs1335645\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"DPM3, EFNA1, PKLR\": {\n \"rs12904\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"EFHD1\": {\n \"rs2140773\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"SLC2A\": {\n \"rs10513686\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"ZNF827\": {\n \"rs4547811\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"CDH6\": {\n \"rs6888304\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"ITGA1\": {\n \"rs4074793\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"MLIP\": {\n \"rs9349693\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"C14orf73\": {\n \"rs944002\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"CD276\": {\n \"rs8038465\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n }\n }\n },\n \"brain health\": {\n \"goal_result\": \"NORMAL\",\n \"goal_result_description\": \"Your brain is supported by a variety of nutrients, including B Vitamins and CoQ10. B Vitamins are difficult to get from a vegan or vegetarian diet, since they're made in large amounts in animal meat and can be hard to find in plant-based foods. If you choose to follow a plant-based diet, supplementing with B Vitamins is critical. Low levels of these nutrients are also responsible for many mood disorders, including depression and anxiety. Even if you consume animal products, you can suffer from a B-Vitamin deficiency. Your genes suggest you are slightly less likely to have deficiencies in these nutrients, but your diet and supplements will play the biggest role in determining your risk.\",\n \"TRAITS\": {\n \"VITAMIN B6 LEVELS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Based on your genetic analysis, your result is correlated with low Vitamin B6 levels.\",\n \"risk_management\": \"Vitamin B6 deficiency can be detected by direct testing, such as a test to measure pyridoxal phosphate levels in the blood. Consuming vitamin B6-rich foods, such as meat, poultry, beans, fish, and nuts, can help maintain levels in the body. Limiting alcohol intake may also be needed for prompt recovery. A vitamin B6 supplement may also be needed, but proper dosage is required to avoid toxicity.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Alkaline Phosphatase (ALPL) and Neuroblastoma Breakpoint Family, Member 3 (NBPF3) are two known genes associated with the maintenance of vitamin B6 and its active form, such as pyridoxal phosphate (PLP), in the body. These genes and their variants have been shown to affect Vitamin B6 metabolism and clearance, with some variants associated with an increased risk of vitamin B6 deficiency. \",\n \"about\": \"One of the most important vitamins for better brain and nerve health is pyridoxine, or Vitamin B6. It has also been reported to help in brain development and functioning, as its role is very crucial in the creation of neurotransmitters. Both deficiency and overload of this essential vitamin can lead to serious health problems, such as seizures and neuropathy.\",\n \"caption\": \"Brain and nerve support\",\n \"ingredients\": {\n \"Vitamin B6\": {\n \"dosage\": \"2 mg\",\n \"description\": \"Vitamin B6 is a water-soluble vitamin that is involved in the transmission of nerve impulses and your body's biosynthesis of serotonin, dopamine, and gamma-aminobutyric acid (GABA) that regulate emotions. It may prevent brain function decline by maintaining levels of homocysteine, an amino acid, in your blood.\"\n }\n },\n \"GENES\": {\n \"ALPL\": {\n \"rs1256335\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"NBPF3\": {\n \"rs4654748\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"ALPL@DUB800\": {\n \"rs1697421\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"ALPL@DUB403\": {\n \"rs1772719\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"VITAMIN B12 LEVELS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Based on your genetic analysis, your result is correlated with high Vitamin B12 levels.\",\n \"risk_management\": \"Maintain a healthy diet. Consume foods that are rich in vitamin B12, such as fish, red meat, poultry, and legumes (fermented). Nutritional yeast and fortified non-dairy milks can be used for vegans and vegetarians. Consider vitamin B12 supplementation as needed. Vitamin B12 deficiency is uncommon but consult your doctor, especially if you have underlying medical conditions. There are available tests to determine vitamin B12 levels.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Vitamin B12 levels are influenced by many different factors, including genetics. Genes such as Galactoside 2-alpha-L-fucosyltransferase 2 (FUT2) and Cubilin (CUBN) have been associated with levels of vitamin B12. These genes influence vitamin B12 levels by affecting the vitamin's absorption in your body. \",\n \"about\": \"Vitamin B12, also known as cobalamin, is an essential vitamin that can only be acquired through food and supplements. Maintaining healthy levels of vitamin B12 is important to reduce the risk of developing neurological problems. Studies show that the level of vitamin B12 in the body is more often related to vitamin absorption rather than poor dietary intake. \",\n \"caption\": \"Mood, brain, and more.\",\n \"ingredients\": {\n \"Vitamin B12\": {\n \"dosage\": \"1 mcg\",\n \"description\": \"Vitamin B12 is a water-soluble vitamin that is required for the development and maintenance of brain, spinal cord, and nerve cells, and is consequently vital in normal neurological function. It is also used during myelin formation, which protects the nerves.\"\n }\n },\n \"GENES\": {\n \"FUT2\": {\n \"rs601338\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"CUBN\": {\n \"rs1801222\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"TCN1\": {\n \"rs526934\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"MUT\": {\n \"rs1141321\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"TCN1@DUB799\": {\n \"rs34324219\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"VITAMIN B9 FOLATE LEVELS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Your results are associated with high Vitamin B9 levels.\",\n \"risk_management\": \"Large quantities of folate may remedy megaloblastic anemia, but not the neurological damage that may occur from a deficiency of vitamin B12. Therefore, some professionals are concerned that a high intakes of folate supplements could cover up the deficiency of vitamin B12 while its neurological consequences become irreversible. \\n\\nSerum folate concentrations are frequently used to test folate levels. However, this indicator is sensitive to recent folate intake and may not reflect long-term folate stores in the body. For long-term measurements, erythrocyte folate concentrations are checked. A physician may order additional laboratory tests to determine the level of homocysteine in your body. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"MTHFR is most commonly associated with the regulation of vitamin B9 in the body. MTHFR variants have been shown to be associated with the levels of vitamin B9 (folate) and homocysteine, a natural byproduct that is known to be toxic to neurons. Some of these genes are linked to folate deficiency, thus associating them with neurodegenerative diseases, including cerebrovascular ischemia (blockage in the brain) and depression.\",\n \"about\": \"Vitamin B9, more commonly known as folic acid or folate, is one of the B-complex vitamins that has important roles in normal nerve and brain functioning. It is also a vital component in the synthesis of neurotransmitters, or the messengers of nerves. Deficiencies of this essential vitamin have been linked to various diseases, including depression and memory loss. \",\n \"caption\": \"Brain function, concentration, and memory.\",\n \"ingredients\": {\n \"Vitamin B9\": {\n \"dosage\": \"320 mcg\",\n \"description\": \"Vitamin B9, also known as folic acid or folate, is a water-soluble vitamin that is critical in maintaining cognitive function. Together with Vitamins B6 and B12, it lowers your homocysteine level. That's important because homocysteine is a risk factor for cognitive decline. \"\n }\n },\n \"GENES\": {\n \"MTHFR\": {\n \"rs12085006\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"MTHFR@DUB840\": {\n \"rs1801133\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"MTHFR@DUB475\": {\n \"rs17350396\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"CoQ10 LEVELS\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Based on your genetic analysis, your result is correlated with low CoQ10 levels.\",\n \"risk_management\": \"CoQ10 levels in the blood can be measured through laboratory testing. People with CoQ10 deficiency can improve levels through supplementation and eating foods that promote CoQ10 production in the body. Consuming foods rich in CoQ10, such as meat, nuts, avocados, and vegetable oils, is recommended. Consult your doctor if you are taking drugs to treat certain conditions, including insulin and chemotherapy medications, to determine the best medical course of action.\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"A large study has revealed that variants of genes such as COLEC12, NRXN-1, DCC, and DNM1 have shown strong associations with CoQ10 levels. These genes have been associated with diseases of the neurons that demand high energy, as well as mental disorders such as Alzheimer's disease, schizophrenia, bipolar disease, and major depressive disorder.\",\n \"about\": \"Co-enzyme Q10 (CoQ10), also known as \\\"ubiquinone,\\\" is found in every cell and plays a vital role in energy production (during cellular respiration in the mitochondria). Studies show that CoQ10 deficiency has implications in organs with high energy requirements, such as the brain and heart, and has been related to medical conditions such as neuronal and cardiovascular diseases. This molecule is naturally produced in the body, but adding more through supplementation has proven highly beneficial.\",\n \"caption\": \"Good for your heart, better for your mind\",\n \"ingredients\": {\n \"Coenzyme Q10\": {\n \"dosage\": \"390 mg\",\n \"description\": \"Coenzyme Q10 is a vitamin-like substance that helps provide energy, especially to organs with a high rate of metabolism. Supplementation improves the concentration of mitochondria in the brain and has been shown to have neuroprotective effects. \"\n },\n \" Lecithin\": {\n \"dosage\": \" 1200 mg\",\n \"description\": \"\\nCoupling CoQ10 supplementation with lecithin has been shown to improve CoQ10 levels in the blood. Lecithin has also been used as a treatment for memory disorders, such as dementia and Alzheimer's disease.\"\n }\n },\n \"GENES\": {\n \"TTC39B\": {\n \"rs686030\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"MMP26\": {\n \"rs12800414\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HNF4A\": {\n \"rs12480807\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"DNM1\": {\n \"rs41313321\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n }\n }\n }\n }\n },\n \"gut health\": {\n \"goal_result\": \"WEAK\",\n \"goal_result_description\": \"Probiotics are living microorganisms in your body. Together with magnesium, they're famous for aiding in digestion and play a critical role in your gut health. Your genetics suggest that your body may not have healthy levels of either probiotics and magnesium.\",\n \"TRAITS\": {\n \"PROBIOTIC NEED\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Based on your genetic analysis, your results are correlated with high probiotic need.\",\n \"risk_management\": \"Probiotic therapy can be done by consuming probiotic foods, including yoghurt, kombucha, kimchi, and probiotic drinks. Consider consuming probiotics, or foods that promote the growth of healthy bacteria, including fruits and vegetables. Taking probiotic supplements is also recommended. Talk to your doctor for appropriate probiotics.\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"A number of gastrointestinal disorders are associated with certain genes, including C11ORF30-LRRC32, CCL2, CCL7, and C11orf30. These diseases are also affected by the state of gut microorganisms. This table shows the genes and their variants that are both associated with gastrointestinal problems, including IBD and Crohn's disease, and an abundance of the disease-associated bacteria.\",\n \"about\": \"A healthy gut requires beneficial microbes. Probiotics, or products that contain live microorganisms, help build up healthy microbes in the gut. Probiotics help in digesting food and improve the movement of the gastrointestinal tract. It also has been shown to alleviate the symptoms of chronic gastrointestinal problems, such as Crohn's disease and irritable bowel disorder (IBD).\",\n \"caption\": \"Healthy bacteria in your gut\",\n \"ingredients\": {\n \"Probiotics \": {\n \"dosage\": \"15 billion CFU\",\n \"description\": \"Probiotics help enrich the good bacteria in your digestive system. They contain certain kinds of live bacteria (e.g. Bifidobacterium, Lactobacillus and Saccharomyces) that can prevent or treat digestive problems, such as diarrhea, ulcers, irritable bowel syndrome, and ulcerative colitis.\"\n }\n },\n \"GENES\": {\n \"C11ORF30-LRRC32\": {\n \"rs2155219\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"CCL2, CCL7\": {\n \"rs3091315\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"C11orf30\": {\n \"rs7927997\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"DAP\": {\n \"rs267939\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Magnesium levels\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your result is correlated with intermediate magnesium levels, and you may require a supplement to keep your body healthy. \",\n \"risk_management\": null,\n \"star_rating\": 3,\n \"snp_table_caption\": \"Various genes can change how effectively your body uses magnesium. Since magnesium is required for energy in the cells of your body, it is one of the most important minerals we ingest. These genes determine how likely you are to have a magnesium deficiency. \",\n \"about\": \"Magnesium is an essential element, required for a wide range of physiological functions. It's critical for muscle contractions, neuromuscular health, glycemic control, the healthy beating of your heart, and blood pressure. Recent studies have pointed out its role in metabolic syndrome and gut health. Furthermore, magnesium supplementation improves metabolic control and reduces insulin resistance. \\n\\nMagnesium is widely distributed in products for plants and animals, and it's used in many beverages. Leafy green vegetables are good sources, such as lettuce, legumes, almonds, seeds and whole grains. Mineral and bottled water may also be sources of magnesium, although magnesium content differs by source and brand (ranging from 1 mg / L to over 120 mg / L). The body usually absorbs between 30% to 40% of the magnesium ingested, so you'll need to consume more than your body actually uses.\",\n \"caption\": \"Improve your digestion with magnesium supplements\",\n \"ingredients\": {\n \"Magnesium\": {\n \"dosage\": \"250 mg\",\n \"description\": \"Magnesium, an important element in the body, is found naturally in several plants, added to many food products, and included in some medications, including antacids and laxatives.\"\n }\n },\n \"GENES\": {\n \"MUC1\": {\n \"rs2066981\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"ATP2B1\": {\n \"rs7965584\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"DCDC5\": {\n \"rs3925584\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"TRPM6\": {\n \"rs12378991\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 2\n }\n },\n \"SHROOM3\": {\n \"rs13146355\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"MECOM\": {\n \"rs448378\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n }\n }\n }\n }\n },\n \"endocrine health\": {\n \"goal_result\": \"NORMAL\",\n \"goal_result_description\": \"The endocrine system is your body's network of hormones and the organs that create them. These hormones can affect your mood, risk for disease, chances of developing diabetes, reproductive health, and more. Iodine, one of the key nutrients in this report, is added to table salt, but many sea salt and 'natural' salt alternatives may not have this nutrient added to it, so be sure to get plenty of it from supplements as well as your diet. The other traits in this report affect your thyroid function and melatonin need, which can affect your hormone balance. Your genetics suggest a typical endocrine system with slightly low risks, but maintaining a healthy sleep schedule and balanced diet is important for everyone. \",\n \"TRAITS\": {\n \"Iodine levels\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your results are correlated with intermediate iodine levels.\",\n \"risk_management\": \"Consume foods rich in iodine, such as seaweed, dairy, iron-fortified foods, fruits, and vegetables, to maintain healthy levels of iodine in the body. Supplements may be also taken to compensate for inadequate iodine intake due to dietary restrictions.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"The activity of the genes in this table may be influenced by iodine intake (and vice-versa). It is important to maintain normal levels of TSH in order to avoid thyroid disorders, such as hypo- or hyperthyroidism, which may develop and lead to adverse effects on growth and development.\",\n \"about\": \"Your thyroid needs to be told how much thyroid hormone to make. It gets that instruction from the pituitary gland. The system works as a feedback loop wherein special cells in your pituitary gland determine the normal thyroxine range for your body. The pituitary cells communicate with your thyroid by sending their own hormone, TSH (thyroid-stimulating hormone), into the blood. \\n\\nTSH production increases thyroidal uptake of iodine and stimulates the synthesis and release of thyroid hormones. In the absence of sufficient iodine, TSH levels remain elevated, leading to goiter, an enlargement of the thyroid gland that reflects the body’s attempt to trap more iodine from the circulation and produce thyroid hormones.\\n\\nIodine in supplements usually occur in a form of iodide which is quickly and almost completely absorbed in the stomach and duodenum (part of your digestive tract). When iodide enters circulation, the thyroid gland concentrates it in appropriate amounts for thyroid hormone synthesis, and most of the remaining amount is excreted in the urine. \",\n \"caption\": \"Thyroid health\",\n \"ingredients\": {\n \"Iodine\": {\n \"dosage\": \"150 mcg\",\n \"description\": \"Iodine is necessary for healthy thyroid function. The iodine in food and iodized salt is present in several forms, including sodium and potassium salts, inorganic iodine (I2), iodate, and iodide, the reduced form of iodine. \"\n },\n \" Ashwagandha\": {\n \"dosage\": \" 450 mg\",\n \"description\": \" \\nAshwagandha [Withania somnifera (L.) Dunal] is recommended by traditional healers for various hormonal disorders, including thyroid imbalances and goiter. Ashwagandha root extract acts as an adaptogen to stabilize the physiological processes, promote homeostasis, and revitalize the body. \"\n }\n },\n \"GENES\": {\n \"PDE8B\": {\n \"rs6885099\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"PDE10A\": {\n \"rs753760\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"CAPZB\": {\n \"rs10799824\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"MAF/LOC440389\": {\n \"rs3813582\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"VEGFA\": {\n \"rs9472138\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"VEGFA@DUB242\": {\n \"rs11755845\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"NR3C2\": {\n \"rs10032216\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"IGFBP5\": {\n \"rs13015993\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"SOX9\": {\n \"rs9915657\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"NFIA\": {\n \"rs334699\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Thyroid function\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your results are correlated with intermediate thyroid function.\",\n \"risk_management\": \"Maintain a healthy, balanced diet, together with regular exercise. If your work schedule or lifestyle makes this difficult, supplementation is suggested, with the guidance of your trusted health care professional. \\n\\nThe only way to check if your thyroid is functioning correctly is to have a thyroid function test, where your blood will be tested to measure your hormone (thyroxine) levels.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Thyroxine production varies from person to person, which causes different metabolisms and developmental rates. Variations in the genes associated with thyroxine production affect the bioactivity of this hormone. This table shows the SNPs associated with thyroid function and how the different genotypes affect your body.\",\n \"about\": \"The thyroid gland is an organ in the endocrine system which releases thyroxine (T4) which regulates body metabolism, growth, and body temperature. \\n\\nBy removing iodine, the brain uses a form of triiodothyronine. This ultimately influences the function of the pituitary gland. The pituitary gland produces a hormone called Thyroid Stimulating Hormone (TSH), which regulates the production of T4. It's an elaborate feedback loop that helps ensure the process runs smoothly. \",\n \"caption\": \"Metabolism and hormonal balance.\",\n \"ingredients\": {\n \"L-tyrosine\": {\n \"dosage\": \"200 mg\",\n \"description\": \"Tyrosine is an important amino acid, needed in the synthesis of the thyroxine hormone. \"\n },\n \" Magnesium\": {\n \"dosage\": \" 350 mg\",\n \"description\": \" \\nMagnesium is a vital mineral used in the production of over 300 proteins and hormones in the human body. An overactive thyroid usually results in magnesium deficiency, which can be corrected with supplements. \"\n }\n },\n \"GENES\": {\n \"DIO1\": {\n \"rs2235544\": {\n \"genotype\": \"CA\",\n \"effect_allels\": 1\n }\n },\n \"FOXE1\": {\n \"rs7045138\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"AADAT\": {\n \"rs11726248\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Melatonin levels\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your result is associated with low melatonin levels. \",\n \"risk_management\": \"If you are experiencing symptoms of insomnia, try to change your sleeping habits. Don't nap during the day. Relax before bedtime. Avoid caffeinated drinks, such as coffee, tea, and soda. Go to bed and get up at consistent times. \\n\\nA sleep study, or polysomnogram, is a test used to measure the quality of sleep using electronic transmissions and recordings of specific physical activities during sleep. To better understand your need for melatonin, consult your sleep specialist or trusted doctor. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"This table shows various genes that affect melatonin production, as well as how much melatonin you need to restore your sleep-wake cycle.\",\n \"about\": \"Melatonin is a hormone that regulates the sleep-wake cycle. It's released by the pineal gland. As night falls, the decrease in light signals the production of melatonin, which in turn signals the body to rest. During changes in timezones, melatonin levels are disrupted, causing changes in its production and ultimately causing what is called \\\"jet lag.\\\" Resisting the urge to sleep at night also causes the pineal gland to produce more melatonin which can exhaust your supply. Constant strain leads to the decrease in gland function, which causes various sleeping disorders.\",\n \"caption\": \"The sleep chemical\",\n \"ingredients\": {\n \"Melatonin\": {\n \"dosage\": \"3 mg\",\n \"description\": \"Melatonin is naturally sourced and generally safe for short-term use (2 weeks). If sleep problems still persist after 2 weeks while taking melatonin, consult your trusted health care professional.\"\n }\n },\n \"GENES\": {\n \"MTNR1A/\\nF11-AS1\": {\n \"rs12506228\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"MTNR1B\": {\n \"rs10830963\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n }\n }\n },\n \"reproductive health (male)\": {\n \"goal_result\": \"WEAK\",\n \"goal_result_description\": \"Male fertility is measured by the amount and healthiness of sperm. Low levels of sperm, or sperm that moves inefficiently, can reduce your fertility. According to your genetics, you may have fertility issues. A poor diet, lack of exercise, obesity, and stress can all reduce the chances of fertility and successful reproduction. Supplementation may help improve sperm health, both in quantity and quality. \",\n \"TRAITS\": {\n \"Male fertility\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your results are associated with low male fertility. \",\n \"risk_management\": \"Proper diet and a healthier lifestyle; avoiding substance abuse, smoking, and alcohol. Wearing loose, cool pants also helps in making the optimal temperature in the testicles for proper meiosis (cell division and reproduction).\\n\\nIn order to check for male fertility problems, tests such as a general physical examination, medical history, and semen analysis are ordered by the doctor. Make sure to consult with your doctor before undertaking any treatments or procedures to have the appropriate treatment. Do not take any pills for \\\"fertility,\\\" \\\"virility,\\\" or \\\"male enhancement\\\" without consulting your doctor, as many of these supplements found online are unproven and potentially dangerous. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Production of sperm in the testicles is a continuous cycle, starting from puberty. The amount of sperm produced is dependent on the rate of meiosis (cell division), and sperm can be checked microscopically for their viability. This table show various genes that affect an individual's production of healthy sperm, which can increase the odds of successful reproduction. \",\n \"about\": \"Human sperm provides half the chromosomes for a zygote (a fertilized egg); it also supplies the X or Y chromosome that induces the sex of the developing baby. The viability of sperm cells is highly dependent on the fertility of the man and the rate of meiosis (cell division) in the testicles. Fertility among men is usually measured by sperm cell count and motility and, in some demographic studies, the family size and birth rate. \",\n \"caption\": \"Healthy sperm and reproduction\",\n \"ingredients\": {\n \"Panax ginseng\": {\n \"dosage\": \"500 mg\",\n \"description\": \"Panax ginseng, popularly known as Korean red ginseng, has been shown to be an effective alternative for treating male infertility and male erectile dysfunction. \"\n },\n \" L-carnitine\": {\n \"dosage\": \" 2000 mg\",\n \"description\": \" \\nL-carnitine, or 3-aminobutyric acid, is a naturally occurring compound and also a semi-essential vitamin-like substance required for human metabolism. \"\n },\n \" Ubiquinone\": {\n \"dosage\": \" 200 mg\",\n \"description\": \" \\nUbiquinone, also known as CoQ10, is an antioxidant required in the electron transport chain. This vitamin-like antioxidant has been widely reviewed in male infertility studies in recent years. \"\n }\n },\n \"GENES\": {\n \"TUSC1/\\nIZUMO3\": {\n \"rs1758734\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"TUSC1\": {\n \"rs12348\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"USP8\": {\n \"rs3098177\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n }\n }\n }\n }\n },\n \"bone health\": {\n \"goal_result\": \"STRONG\",\n \"goal_result_description\": \"While calcium is famous for its effects on bone health, Vitamin D, Vitamin K, and phosphorus are also important. Vitamins D, K and phosphorus help in calcium absorption and maintaining your bone's strength. Weak bones may become brittle or even break, which can be potentially deadly. Fortunately, you appear to have good bone health status, as long as you consume a balanced diet.\",\n \"TRAITS\": {\n \"Calcium levels\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your results are correlated with intermediate calcium levels.\",\n \"risk_management\": \"Your goal is to keep your calcium levels balanced and bones healthy. Drink plenty of water to stay hydrated, quit smoking to decrease the risk of bone loss, exercise regularly, and do strength training to promote bone strength. Calcium supplementation is best taken at 500 mg per intake. For instance, if you need to increase your intake to 1500 mg, it is best to take 500 mg with every meal for optimized absorption. \\n\\nIf you're worried about your calcium levels, consult your physician about getting a blood test and ask for a proper diagnosis.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Individuals have different metabolic rates, which in turn have different rates of depositing calcium in the bones. This table shows genetic variations that are associated with calcium deposits for healthier bones, which can help identify medical and supplement needs in order to avoid bone-related diseases.\",\n \"about\": \"Calcium is essential to the integrity of the skeletal system. During childhood and adolescence, the body constantly replenishes calcium in the bones with food; excess calcium supplies are stored up in the marrow for bone development and is used for strengthening the body's frame. As we age, calcium deposits depreciate, and bones can no longer store larger amounts. A good supply of calcium is essential, especially for adults, to avoid bone damage. Decreased calcium is correlated with bone-related illnesses, such as osteoporosis.\",\n \"caption\": \"Strong, healthy bones.\",\n \"ingredients\": {\n \"Calcium\": {\n \"dosage\": \"1000 mg \",\n \"description\": \"Calcium is a mineral found in several foods. Almost all calcium is stored in bones and teeth, where it supports their structure and hardness.\"\n }\n },\n \"GENES\": {\n \"LRP5\": {\n \"rs4988321\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"CCDC170\": {\n \"rs4870044\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"LRP5@DUB241\": {\n \"rs3736228\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"TNFRSF11B\": {\n \"rs4355801\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"WNT16\": {\n \"rs3801387\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"CASR\": {\n \"rs1801725\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"DGKD\": {\n \"rs1550532\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"GCKR\": {\n \"rs780094\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"LINC00709\": {\n \"rs10491003\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"CARS\": {\n \"rs7481584\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"LOC105370176\": {\n \"rs7336933\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"CYP24A1\": {\n \"rs1570669\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Vitamin D levels\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Your results are correlated with high Vitamin D levels.\",\n \"risk_management\": \"Vitamin D toxicity is very rare but can cause serious problems. If you suspect that you may have this issue, consult with your doctor immediately. As an initial treatment, you may stop your Vitamin D intake and restrict your calcium consumption. \\n\\nBefore taking any precautionary measures, you may want to test your Vitamin D levels every 3 months to make sure that you really need to change your intake, as low levels of Vitamin D are much more common. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"People have different calcium and phosphorus absorption rates due to the amount of vitamin D they need to facilitate the transfer of those nutrients to the bloodstream. This table shows genetic variants responsible for the efficacy of vitamin D in facilitating elemental transfer, as well as your vitamin requirements.\",\n \"about\": \"Vitamin D is an important cofactor in the absorption and storage of calcium in the bones. Levels of vitamin D are influenced by many factors, including sun exposure, age, body mass index, dietary intake of certain foods, such as fortified dairy products and oily fish, supplements, and genetic factors.\",\n \"caption\": \"Bone support, obesity, and high blood pressure.\",\n \"ingredients\": {\n \"Vitamin D\": {\n \"dosage\": \"200 IU (5 mcg) \",\n \"description\": \"Vitamin D exists in two main biological forms — D2 (ergocalciferol) and D3 (cholecalciferol). Typically, D2 comes from plants, and D3 comes from animals. According to studies, Vitamin D3 (cholecalciferol) is more effectively absorbed than D2, so D3 is the recommended form, especially if you're not following a vegetarian or vegan diet.\"\n }\n },\n \"GENES\": {\n \"GC\": {\n \"rs4588\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"NADSYN1\": {\n \"rs12785878\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"CYP2R1\": {\n \"rs10741657\": {\n \"genotype\": \"GA\",\n \"effect_allels\": 1\n }\n },\n \"CYP24A1\": {\n \"rs17216707\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"AMDHD1\": {\n \"rs6538691\": {\n \"genotype\": \"GT\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Vitamin K levels\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Your genes are associated with higher levels of Vitamin K. \",\n \"risk_management\": null,\n \"star_rating\": 2,\n \"snp_table_caption\": \"By knowing your genetic need for Vitamin K, you may be able to alleviate existing problems correlated with its deficiency and may even prevent yourself from being deficient in the future, which can help maintain better overall bone health. \",\n \"about\": \"Vitamin K is necessary for efficient blood clotting, bone metabolism, and regulating your blood calcium levels. It is a fat-soluble vitamin that is naturally present in some foods and is available as a dietary supplement. \\n\\nIn human epidemiological and intervention trials, there is a strong line of evidence that clearly demonstrates that vitamin K can enhance the bone health. Reports in human intervention studies have shown that vitamin K in patients with osteoporosis can not only improve bone mineral density but also actually reduce fracture rates. In addition, there is evidence in human intervention studies that vitamins K and D, work in synergism on bone density.\",\n \"caption\": \"Bone health, calcium levels, and more.\",\n \"ingredients\": {\n \"Vitamin K2\": {\n \"dosage\": \"90 mcg\",\n \"description\": \"Vitamin K2, in the form of menaquinone-7 (MK-7) was associated with improved bone strength and overall bone health.\"\n }\n },\n \"GENES\": {\n \"VKORC1 or PRSS53\": {\n \"rs7294\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"VKORC1\": {\n \"rs2884737\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"GGCX\": {\n \"rs10187424\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"MGP\": {\n \"rs4236\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Phosphorus levels\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your result is correlated with intermediate (healthy) phosphorus levels in the blood.\",\n \"risk_management\": \"Phosphorus often comes in the form of dipotassium phosphate, disodium phosphate, phosphatidylcholine, or phosphatidylserine in dietary supplements. Research has not shown that any particular form of phosphorus supplementation is better than the others. \\n\\nVarious foods contain phosphorus, including dairy products, meats and poultry, fish, eggs, nuts, legumes, vegetables, and grains. Milk products contribute approximately 20% of the overall phosphorus intake in the United States, while baked products (e.g. breads, tortillas, and pastries) contribute 10%. Chicken and vegetables add 5% each. In comparison to plant sources, phosphorus from animal sources have higher absorption rates. Studies have shown that the absorption rate of phosphorus in milk is about 40-70%. \",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Phosphorus isn't one of the most popular or well-known minerals, but it's critical for your overall health. These genes have been shown to potentially decrease or increase your levels of phosphorus and may indicate the need for a phosphorus supplement to maintain good health.\",\n \"about\": \"Phosphorus isn't as famous as calcium, but it's just as important for your bones and teeth. Around 85% of your body's phosphorus is in your bones and teeth!\\n\\nWhile you probably haven't been urged to get more phosphorus by toothpaste commercials and meal replacement shakes, the fact is that this crucial nutrient can literally make or break your bones. And while calcium supplements might be recommended in some cases, without sufficient phosphorous, calcium can't work effectively to improve or strengthen your bones. \",\n \"caption\": \"Bones, teeth, and phosphorus\",\n \"ingredients\": {\n \"Phosphorus\": {\n \"dosage\": \"1000 mg\",\n \"description\": \"Phosphorus is an integral part of bones, teeth, DNA, and RNA. Many different foods contain phosphorus, primarily in the form of phosphates and phosphate esters.\"\n }\n },\n \"GENES\": {\n \"ALPL, NBPF3\": {\n \"rs1697421\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"CSTA\": {\n \"rs17265703\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"IP6K3\": {\n \"rs9469578\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"PDE7B\": {\n \"rs947583\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"C12orf4\": {\n \"rs2970818\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n }\n }\n },\n \"kidney health\": {\n \"goal_result\": \"STRONG\",\n \"goal_result_description\": \"The kidneys are, quite simply, the blood-filtration system of your body. The waste is turned into urine. All of the blood in your body passes through the kidneys several times a day. Your kidney health is made up of two main parts: glomerular filtration rate (the efficiency of your kidneys) and your risk to proteinuria (the levels of protein found in urine). Your DNA suggests you may have excellent kidney health. Drinking plenty of water and avoiding nicotine and alcohol are important in maintaining good kidney health.\",\n \"TRAITS\": {\n \"Glomerular filtration rate\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Your genes are significantly associated with a high GFR. \",\n \"risk_management\": \"Having high GFR is a good indication of properly functioning kidneys; however, it is best to consult your physician regarding this to get the best possible diagnosis. \\n\\nAdditional tests may include urine tests, ultrasound or CT scan, or a kidney biopsy. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Cleaning the blood stream is essential: it is done by our kidneys, which filter toxins and expels them in the form of urine. The rate of filtration is dependent on a person's lifestyle, but it's also dependent on their genotype. This table shows the different variations in genes that may indicate kidney function associated with glomerular filtration rate.\",\n \"about\": \"Glomerular filtration rate (GFR) is used to assess how much blood passes through the glomeruli (nerves in your kidney) per minute to filter out dead or old cells in the bloodstream, as well as unnecessary contaminants. Identification of kidney health is essential in determining overall well-being, since it involves the removal of toxins and foreign matter in the bloodstream.\\n\\nGFR is calculated from blood creatinine levels. Normal GFR can vary according to age (as you get older, it can decrease). The normal value for GFR is 90 or above. A GFR below 60 is a sign that the kidneys are not working properly. Once the GFR decreases below 15, one is at high risk for needing treatment for kidney failure, such as dialysis or a kidney transplant.\",\n \"caption\": \"Cleaning your blood\",\n \"ingredients\": {\n \"Selenium\": {\n \"dosage\": \"55 mcg \",\n \"description\": \"Selenium is a crucial element that performs important biological functions. The kidneys have the highest selenium level among all organs, and selenium is shown to protect the kidneys by reducing renal toxicity damage, increasing the glomerular filtration rate, and reducing inflammation. \"\n }\n },\n \"GENES\": {\n \"CX3CR1\": {\n \"rs3732379\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"SHROOM3\": {\n \"rs17319721\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"MTTP\": {\n \"rs1800804\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"PIP5K1B\": {\n \"rs1556751\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"APOA5\": {\n \"rs662799\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"BRAP\": {\n \"rs3782886\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"SPATA5L1\": {\n \"rs2453533\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"MCP1\": {\n \"rs1024611\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"CPS1\": {\n \"rs1047891\": {\n \"genotype\": \"CA\",\n \"effect_allels\": 1\n }\n },\n \"BCAS3\": {\n \"rs9895661\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Proteinuria\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Your results are correlated with an intermediate risk of proteinuria.\",\n \"risk_management\": \"In mild or temporary proteinuria, no treatment may be necessary.\\n\\nDrugs are sometimes prescribed, especially in people with diabetes and/or high blood pressure. These may come from two classes of drugs:\\nACE inhibitors (angiotensin-converting enzyme inhibitors)\\nARBs (angiotensin receptor blockers)\\n\\nKidney disease often has no early symptoms. One of its first signs may be proteinuria that's discovered by a urine test done during a routine physical exam. Blood tests will then be done to see how well the kidneys are working.\",\n \"star_rating\": 2,\n \"snp_table_caption\": \"Although kidney health is highly associated with lifestyle, the build-up of metabolized proteins is affected by genetic factors. This table shows your predisposition to kidney damage associated with proteinuria.\",\n \"about\": \"When kidney function is impaired, proteins build up in the tissue, indicating infection or various illnesses. The build up of proteins, such as creatine or albumin, is called proteinuria. It ultimately causes kidney damage if untreated. Build-up of protein in the kidneys is highly associated with hazardous lifestyles, while the onset of damage is also affected by genetics. Having abnormal levels of proteins in the urine may be an early indicator of kidney problems. \",\n \"caption\": \"Protein in the urine.\",\n \"ingredients\": {\n \"Turmeric\": {\n \"dosage\": \"500 mg (1-2x daily)\",\n \"description\": \"The medicinal properties of turmeric are mainly caused by curcumin, which has been shown to have antioxidant and anti-inflammatory effects on the kidneys. \"\n },\n \" Omega 3\": {\n \"dosage\": \" 1.6 g\",\n \"description\": \" \\nOmega-3 fatty acids are composed mainly of alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). Omega-3s play important roles in the body as components of the phospholipids that form the structures of cell membranes. \"\n }\n },\n \"GENES\": {\n \"LRP2\": {\n \"rs2075252\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"CUBN\": {\n \"rs1801239\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"FOXD2-TRABD2B\": {\n \"rs10157710\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"CWC27\": {\n \"rs3776051\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"AGR3-AHR\": {\n \"rs4410790\": {\n \"genotype\": \"CT\",\n \"effect_allels\": 1\n }\n },\n \"CCT2\": {\n \"rs3201\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n },\n \"ZFP36L1-\\nACTN1\": {\n \"rs7142145\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"CYP1A2-\\nCYP1A1\": {\n \"rs2472297\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n }\n }\n }\n }\n },\n \"eye health\": {\n \"goal_result\": \"NORMAL\",\n \"goal_result_description\": \"Vitamin A is a critical nutrient that protects the surface of the eye and improves overall vision. It can also decrease the risk of vision loss. Visual acuity is simply the “sharpness” of your eyesight, which can be affected by the optic nerves, brain, and your ability to focus on a specific image. Both Vitamin A levels and your visual acuity are at least partially genetic, and may affect your eyesight, both currently and as you age. You appear to have good overall eye health, but a balanced diet with plenty of fruits and veggies is critical. You can also protect your eyes with proper eyewear, blue-light filters, and proper supplementation.\",\n \"TRAITS\": {\n \"Visual acuity\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Your genetics are associated with high visual acuity.\",\n \"risk_management\": \"Maintaining a healthy diet and lifestyle are key factors in keeping your eyes in good shape. Avoid smoking and limit your exposure to phones, tablets, computers, televisions, and other blue-light emitting devices. \\n\\nRegular eye examinations are recommended, especially if you have a family history of eye-related problems. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Your eyesight is dependent on both the eyes themselves, as well as certain nerves. People have different reactions to damage and stress, which is partly genetic. This table shows the different genes associated with visual acuity, which can help identify precautionary measures for preserving good eyesight.\",\n \"about\": \"The ability of the brain to process images is highly dependent on the visual acuity of the eye. The clarity and sharpness of the image depends on the eyes' ability to auto-focus and adjust, as well as the brain's perception of the information coming from the optic nerve. Eyesight may be compromised when the eyes have acute damage or are suffering from certain conditions, such as age-related macular degeneration or cataracts.\",\n \"caption\": \"How \\\"sharp\\\" is your vision?\",\n \"ingredients\": {\n \"Lutein\": {\n \"dosage\": \"3.6 mg\",\n \"description\": \"Lutein is a carotenoid that acts as a color pigment in the macula and retina of the eyes. According to studies, oral lutein supplementation prevents eye diseases that lead to vision loss and cataracts in adults. \"\n },\n \" Zeaxanthin\": {\n \"dosage\": \" 2 mg\",\n \"description\": \" \\nZeaxanthin is an antioxidant that helps in filtering the harmful high-energy blue wavelengths of light, and it protects and maintains healthy cells in the eyes. \"\n },\n \" Zinc\": {\n \"dosage\": \" 9.6 mg\",\n \"description\": \"\\nZinc is is an essential mineral involved in numerous stages of cellular metabolism. Studies indicate that zinc supplementation may decrease the risk of progression to advanced age-related macular degeneration. \"\n },\n \" Copper\": {\n \"dosage\": \" 0.9 mg\",\n \"description\": \"\\nCopper is an essential mineral functioning as a cofactor for several enzymes (cuproenzymes) involved in energy production, iron metabolism, neuropeptide activation, connective tissue synthesis, and neurotransmitter synthesis. Copper supplementation is correlated to a 25% reduction in the risk of vision loss. \"\n }\n },\n \"GENES\": {\n \"SLC23A2\": {\n \"rs1279683\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"TIMP1/ \\nSYN1/ \\nMIR4769\": {\n \"rs4898\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"PLXDC2\": {\n \"rs7081455\": {\n \"genotype\": \"TG\",\n \"effect_allels\": 1\n }\n },\n \"APEX1\": {\n \"rs1130409\": {\n \"genotype\": \"TG\",\n \"effect_allels\": 1\n }\n },\n \"OPTN\": {\n \"rs11258194\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"XRCC1\": {\n \"rs25487\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 2\n }\n },\n \"CAV2\": {\n \"rs1052990\": {\n \"genotype\": \"TG\",\n \"effect_allels\": 1\n }\n },\n \"TMCO1\": {\n \"rs4656461\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"TLR4\": {\n \"rs4986791\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"ZP4\": {\n \"rs547984\": {\n \"genotype\": \"AC\",\n \"effect_allels\": 1\n }\n }\n }\n },\n \"Vitamin A levels\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your result is correlated with low Vitamin A levels.\",\n \"risk_management\": \"The bio-availability of pro-vitamin A varies widely depending on the source. Therefore, supplements provide the most reliable method of supplying sufficient amounts of Vitamin A.\\n\\nPlasma retinol concentrations are useful indicators of healthy or normal Vitamin A levels. Be sure to ask your doctor before taking any food or dietary supplements to prevent a vitamin overdose.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"This SNP table shows genetic variants associated with the levels of Vitamin A needed specifically for eye health, although Vitamin A is necessary for many other functions as well. \",\n \"about\": \"Your Vitamin A (VA) levels is dependent on the blood concentration of vitamin A. VA blood concentration is affected by numerous factors, including dietary VA intake, VA absorption efficiency, your body's ability to create a usable form of the vitamin, VA tissue uptake, and more. Most of these factors are affected by genetic variations that influence your Vitamin A metabolism. \\n\\nLow levels of Vitamin A may indicate deficiency, while high VA levels are associated with toxicity. Keeping your VA levels at the normal range is crucial to reduce susceptibility of common eye conditions. \",\n \"caption\": \"Antioxidant for eyes, bones, hair, and more\",\n \"ingredients\": {\n \"Vitamin A \": {\n \"dosage\": \"1200 mcg \",\n \"description\": \"Vitamin A is an essential nutrient required by humans in small amounts for: normal eye functioning; growth and development; immune function; and reproduction. There are two popular forms of Vitamin A, namely, preformed retinol (mainly as \\\"retinyl ester\\\") and provitamin A carotenoids.\"\n }\n },\n \"GENES\": {\n \"FFAR4/\\nRBP4 \": {\n \"rs10882272\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"TTR\": {\n \"rs1667255\": {\n \"genotype\": \"CA\",\n \"effect_allels\": 1\n }\n },\n \"CAPN8/\\nCAPN2\": {\n \"rs12137025\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"PKD1L2\": {\n \"rs6420424\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PKD1L2@DUB775\": {\n \"rs8044334\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"chr16:81230992\": {\n \"rs6564851\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n }\n }\n },\n \"hair and nails \": {\n \"goal_result\": \"STRONG\",\n \"goal_result_description\": \"Biotin is crucial for healthy hair, skin, and nails. Your genetics suggest that you have good levels of biotin, but diets high in processed food are less likely to supply the levels necessary, so supplementation may be required.\",\n \"TRAITS\": {\n \"Biotin levels\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"Your result is correlated with high biotin levels.\",\n \"risk_management\": \"Even though this genetic test shows that you don't need a biotin supplement, it's still important to consume biotin-rich foods, like eggs, cheese, almonds, and mushrooms, in order to prevent this deficiency. Anyone may become deficient if their diet and exercise routine is inadequate.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"The BTD gene encodes biotinidase that causes the breakdown of biotin from biocytin or biotinyl proteins. Mutations in this gene have been associated with biotin deficiency.\",\n \"about\": \"According to the American Academy of Dermatology, getting adequate amounts of biotin through food or supplements may improve nail health and help you grow stronger, thicker hair. A systematic review of biotin's effects on hair and nail growth provides evidence for “clinical improvement in patients who had an underlying pathology for poor hair or nail growth.” \\n\\nIn other words, biotin supplements lead to a statistically significant improvement in hair and nails in people with weak, brittle, or otherwise damaged hair and nails. \",\n \"caption\": \"Healthy hair, skin, and nails.\",\n \"ingredients\": {\n \"Biotin\": {\n \"dosage\": \"30 mcg\",\n \"description\": \"Biotin, or Vitamin B7, is a water-soluble vitamin that is known to strengthen hair and nails. It is also used as a cofactor for enzymes that are involved in the metabolism of amino acids, glucose, and fatty acids, so it supports your metabolic functions and improves your overall health.\"\n }\n },\n \"GENES\": {\n \"BTD\": {\n \"rs13078881\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n }\n }\n }\n }\n}"},{"id":"418d89d4-52b3-44d4-a2e2-48820111800d","name":"Immunity & Vitamins Report - Missing Required Paramater","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1c2b7b12b289_709f9fd16bb5_8aafce768660\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/imv/report"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; 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Description: This Endpoint generates/retrieves the latest disease report for any customer

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

report_json

JSON

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mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"fb550a0c94499ed94639f7cb3040f548\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"25bff45a-b2a4-42ef-b8dd-178500fe7b68"},{"key":"X-Runtime","value":"0.024001"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Disease Report Generated\",\n \"report_json\": {\n \"Age related Macular Degeneration\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"Based on your DNA, you may have an intermediate risk of developing age-related macular degeneration. \",\n \"risk_management\": \"Eye doctors can check for AMD as part of a comprehensive dilated eye exam. The exam is simple and painless — your doctor will give you some eye drops to dilate (widen) your pupil and then check your eyes for AMD and other eye problems. Your doctor may also recommend doing a test called an optical coherence tomogram (OCT). This test lets the doctor see the back of your eye. \\n\\nThere is no cure for AMD, but you may improve your eye health and reduce your risks. You may even be able to slow the progression of the disease once diagnosed. Research shows that you can improve your outlook by making these healthy \\u202fchoices: \\n\\nQuit smoking — or don't start.\\nGet regular physical activity.\\nMaintain a healthy blood pressure and cholesterol\\u202flevels.\\nEat healthy foods, including leafy green vegetables and\\u202ffish.\\n\\nThere's no substitute for the quality of life good vision offers. Adding certain nutrients to your diet every day—either through foods or supplements—can help save your eyesight. In a large human clinical trial, Age-Related Eye Disease Study (AREDS2) by the National Eye Institute Researchers, linked lutein and zeaxanthin (10 mg lutein and 2 mg zeaxanthin per day), vitamin C (500 mg per day), vitamin E (400 mg per day), and zinc (40 to 80 mg daily) to slowing the progression of age-related macular degeneration (AMD) and reducing the risk of its development.\",\n \"risk_factors\": [\n \"You are more likely to develop AMD if you:\",\n \"Eat a diet high in saturated fat (found in foods like meat, butter, and cheese)\",\n \"Are overweight\",\n \"Smoke cigarettes or other tobacco products\",\n \"Are over 50 years old\",\n \"Have hypertension (high blood pressure)\",\n \"Have a family history of AMD\",\n \"Have heart disease \",\n \"Have high cholesterol levels \",\n \"Are Caucasian\"\n ],\n \"signs_and_symptoms\": [\n \"In its early stages, the following signs of macular degeneration can go unnoticed:\",\n \"Gradual loss of ability to see objects clearly.\",\n \"The shape of objects appears distorted.\",\n \"Straight lines look wavy or crooked.\",\n \"Loss of clear and distinct colors.\",\n \"A dark or empty area in the center of your vision.\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Variations in the two genes analyzed have been closely connected to both the development of AMD and whether it progresses to the advanced stages of the condition. The presence of these genetic variants does not mean that you will definitely acquire AMD. These variations simply mean that you may have a higher risk of having an AMD or developing it in the future.\\n\\nThis test does not cover all possible variants in the present genes or other genes associated with increased risk of AMD, so regular eye checkups are recommended for all people, especially those who are aging. \",\n \"about\": \"Age-related macular degeneration (AMD) is an eye condition that can obscure the sharp, central vision you need for reading and other related activities, such as driving. \\\"Age-related\\\" means that it often occurs in older people. \\\"Macular\\\" simply refers to a part of your eye called the macula.\\n\\nAMD is a common eye disease and the leading cause of vision loss for people age 50 and older. AMD does not cause total blindness; however, losing your central vision can make it more difficult to see faces, drive, or perform close-up tasks, like cooking or trying to fix things around the house.\\n\\nAMD is happens very slowly in some people. You may not experience vision loss for a long time, even if you have early AMD. AMD progresses faster for other people and can potentially lead to a loss of central vision in one eye or both eyes.\",\n \"caption\": \"Loss of vision as you age\",\n \"active_variants\": 1,\n \"GENES\": {\n \"CFH\": {\n \"rs1061170\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"ARMS2\": {\n \"rs10490924\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n }\n }\n },\n \"Celiac Disease\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your genetics show that you have a low risk of developing Celiac disease. \",\n \"risk_management\": \"Even though your genes analyzed here suggest that you have a low likelihood of developing Celiac disease, it's still best to consult your trusted doctor for a proper clinical diagnosis. Adding to this genetic test, your doctor may diagnose Celiac disease with a medical and family history, physical exam, and other tests, including blood tests or a biopsy. \\n\\nIf you think you might have Celiac disease, don't try avoiding gluten without talking to your doctor first. If you are diagnosed with Celiac disease, your doctor will give you a special gluten-free diet. In the past decades, more people without Celiac disease have adopted a gluten-free diet, believing that avoiding gluten is healthier or could help them lose weight. No current data suggests that the general public should maintain a gluten-free diet for weight loss or better health.\\n\\nAvoiding gluten-rich foods, such as healthy whole wheat products, may be more dangerous to your overall health if you do not have Celiac disease, so be careful and speak with your doctor before making changes to your diet. \",\n \"risk_factors\": [\n \"Previous studies show that Celiac disease occurs only in individuals who have specific genes. These genes are common and carry about one third of the population. Individuals also need to eat gluten-containing food to get celiac disease. Currently, scientists do not know exactly what causes Celiac disease in people at risk who have been eating gluten for a long time. Sometimes the disease runs in families. \",\n \"Approximately 10-20% of close relatives of Celiacs are also affected. Your chances of developing Celiac disease increase when you have specific variants in your genes. Certain genetic variants and other factors, such as things in your environment, may lead to developing Celiac disease.\"\n ],\n \"signs_and_symptoms\": [\n \"If you have celiac disease, you may have digestive problems or other symptoms. Digestive symptoms are more common in children and can include:\",\n \"Bloating, or a feeling of fullness or swelling in the abdomen.\",\n \"Chronic diarrhea.\",\n \"Constipation.\",\n \"Gas.\",\n \"Nausea.\",\n \"Pale, foul-smelling, or fatty stools that float.\",\n \"Stomach pain.\",\n \"Vomiting.\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"The risk of developing Celiac disease is increased by certain genetic variants found in the HLA-DQA1 and HLA-DQB1 genes. These genes provide instructions for making proteins that play a critical role in the immune system. \\n\\nThis test does not cover all possible variants in the present genes or other genes associated with increased risk of Celiac disease, so it's possible that people with a low risk of Celiac disease in this test may develop the disease. \",\n \"about\": \"Celiac disease is a severe autoimmune disease that occurs in genetically predisposed people where the ingestion of gluten causes harm to the small intestine. It is reported that 1 in 100 people across the world are affected. 2.5 million Americans are undiagnosed and at risk for long-term health health problems caused by long-term exposure to gluten.\\n\\nWhen people with Celiac disease eat gluten (a protein found in wheat, rye, and barley), their body has an immune reaction that targets the small intestine. These attacks disrupt the villi, small finger-like objects that line the small intestine and promotes the absorption of nutrients. When the villi are damaged, nutrients cannot be adequately absorbed into the body. Therefore, people who continue to eat gluten with Celiac disease may ultimately damage their nutritional levels and general health.\\n\\nCeliac disease tends to be clustered in families. Parents, siblings, or children (first-degree relatives) of people with Celiac disease have a 4-15% chance of developing the disease. However, the pattern of inheritance is still unknown. \",\n \"caption\": \"Your immune response to gluten\",\n \"active_variants\": 0,\n \"GENES\": {\n \"HLA-DQB1\": {\n \"rs7454108\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"HLA-DQA1\": {\n \"rs2187668\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Iron Overload Disorder \": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Based on your genetic results, you may have a low risk of developing iron overload disorder. \",\n \"risk_management\": \"Even though you have a low risk of iron overload disorder compared to the general population, you should consult your doctor, especially if you have any of the symptoms. Your doctor may order a blood test. Affected people can be diagnosed through blood tests for iron levels.\\n \\nIf you are diagnosed with iron overload disorder or hereditary hemochromatosis, your doctor may recommend reducing you iron intake and implementing regular blood removal to reduce excess iron in the bloodstream. Additionally, your doctor may recommend:\\n\\nAnnual blood tests to check your iron levels.\\nLiver biopsy to check for cirrhosis.\\nIron chelation therapy (if you cannot have blood removed) which involves medicine used to lower the amount of iron in your body.\\nDietary changes, such as avoiding multivitamins, vitamin C supplements, and iron supplements, which can increase iron throughout your body.\\nAvoiding alcohol (because alcohol increases the risk of liver damage).\\nSteps to prevent infections, including avoiding uncooked fish and shellfish, and getting recommended vaccinations, including those against hepatitis A and B.\",\n \"risk_factors\": [\n \"Due to the extremely variable nature of iron overload disorder, additional factors are likely to play a part in the development and progression of the condition for each individual including: \",\n \"Genetic\",\n \"Physiological\",\n \"Environmental causes\"\n ],\n \"signs_and_symptoms\": [\n \"Hereditary hemochromatosis may not have any noticeable symptoms in the early stages. However, when symptoms do appear, you may experience the following:\",\n \"Chronic fatigue (feeling very tired).\",\n \"Joint pain.\",\n \"Pain in the knuckles.\",\n \"Lack of energy.\",\n \"Abdominal (belly) pain.\",\n \"Loss of sex drive.\",\n \"Loss of body hair.\",\n \"Heart flutters.\",\n \"Memory fog.\",\n \"Weight loss.\",\n \"Weakness.\",\n \"Abnormal coloring of the skin (gray or bronze).\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"This report primarily deals with hereditary hemochromatosis associated with the HFE genetic variants.\\n\\nThis test does not cover all possible variants in the present gene or other genes associated with an increased risk of iron overload disorder. Consuming too much iron, even without a genetic predisposition, may result in iron overload. \",\n \"about\": \"Iron overload disorder, or more commonly known as hereditary hemochromatosis, is a condition that causes the body to absorb too much iron from your food. Excess iron is stored in the body's tissues and organs, especially the skin, heart, liver, pancreas, and joints. Since humans cannot increase the excretion of iron, residual iron can overload and gradually damage tissues and organs.\\n\\nAccumulation of iron in hereditary hemochromatosis happens gradually throughout many years. Inevitably, iron accumulation causes tissue damage and impairs the functioning of the affected organs. Symptoms may not become apparent in many affected individuals until some point between the ages of 40 and 60 years. Onset is typically earlier for males than females.\",\n \"caption\": \"How \\\"healthy\\\" food can hurt you\",\n \"active_variants\": 0,\n \"GENES\": {\n \"HFE\": {\n \"rs1800562\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"HFE@DUB982\": {\n \"rs1799945\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Parkinson's Disease\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"The variants tested do not give you an increased risk of Parkinson’s disease.\",\n \"risk_management\": \"You may not have a genetic risk of Parkinson’s disease, but environmental factors play a big role for the development of this condition. Consult a doctor if you have a family history of Parkinson’s disease. There is no cure yet for this condition, but treatments can relieve symptoms. There is no specific test for the disease and the doctor will diagnose you based on symptoms, family and medical histories, and physical examinations. A SPECT scan can be done to help with the diagnosis. The treatment options for patients with advanced PD are supportive therapies and drug medications. Dietary changes such eating more foods with high fiber and salt have been shown to improve some symptoms.\",\n \"risk_factors\": [\n \"Development of the disease may be caused by the following factors: \",\n \"Age: Parkinson’s disease usually appears after the age of 50.\",\n \"Heredity: You are more likely to develop Parkinson’s disease if you have a family history of the condition.\",\n \"Sex: Men are more likely to develop Parkinson’s disease than women.\",\n \"Environment: Exposure to environmental toxins, such heavy metals and pesticide, can increase the risk of Parkinson’s disease.\"\n ],\n \"signs_and_symptoms\": [\n \"Common symptoms include: \",\n \"Tremor or shaking that usually starts in a limb\",\n \"Slowed movements\",\n \"Muscle stiffness\",\n \"Impaired balance and posture\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"The genetic variants used in this analysis are known mutations in the LRRK2 and GBA genes and are clinically associated with Parkinson’s disease. It is still unclear how variants in these genes lead to the disease. LRRK2 gene variants have been observed in families with PD, while the variant in the GBA gene has been linked to an increased risk of developing PD. Just one copy of the risk allele in these variants is enough to increase the risk of developing PD. \\n\\nThis test does not cover all possible variants in the present genes or other genes associated with increased risk of PD.\",\n \"about\": \"Parkinson's disease (PD) is a neurodegenerative disease characterized by shaking, stiffness, postural instability, and problems with body movement. This condition occurs when several areas of the brain that control balance and movement become impaired. Impairment leads to a reduction of the chemical dopamine, which conveys signals for smooth movement, causing symptoms of the disease. The most common form of PD is late-onset Parkinson's disease, which appears after the age of 50. The cause of this disease is a combination of genetic and environmental factors.\",\n \"caption\": \"Nerve cell damage leading to tremors\",\n \"active_variants\": 0,\n \"GENES\": {\n \"GBA\": {\n \"rs76763715\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"G6PD Deficiency\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Based on your genetic results, you may have a low risk of G6PD deficiency.\",\n \"risk_management\": \"Your result may show that you are genetically predisposed to having good G6PD levels; however, it is still best to consult your doctor and have your blood tested. If your doctor suspects that you are G6PD-deficient, they will conduct a variety of blood tests to confirm a diagnosis and rule out other conditions. The diagnosis depends on demonstrating decreased activity of the G6PD enzyme using either a quantitative test or a screening test, such as a fluorescent spot test. \\n\\nPreventing triggers for the illness is the most important aspect of G6PD deficiency management. Blood transfusions or even an exchange transfusion may be required by your doctor in cases of acute hemolytic anemia.\",\n \"risk_factors\": [\n \"Aside from genetics, individuals with G6PD deficiency suffering from hemolytic anemia typically have the following trigger:\",\n \"Illnesses, such as bacterial and viral infections.\",\n \"Some painkillers and fever-lowering drugs.\",\n \"Certain antibiotics (most often those with \\\"sulf\\\" in their names).\",\n \"Some antimalarial drugs (most often those with \\\"quine\\\" in their names).\",\n \"Fava beans (also called broad beans).\",\n \"Naphthalene (a chemical found in mothballs and moth crystals). \"\n ],\n \"signs_and_symptoms\": [\n \"Individuals with G6PD deficiency typically don't show symptoms. People with hemolytic anemia may have the following symptoms if a lot of red blood cells are destroyed: \",\n \"Paleness. (In darker-skinned children, paleness is sometimes best seen in the mouth, especially on the lips or tongue.)\",\n \"Extreme tiredness or dizziness.\",\n \"Fast heartbeat.\",\n \"Fast breathing or shortness of breath.\",\n \"Jaundice (yellow skin and eyes).\",\n \"An enlarged spleen.\",\n \"Dark, tea-colored pee.\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"G6PD deficiency is induced by variations in the G6PD gene and maps of the X chromosome.\\n\\nThis test does not cover all possible variants in the present gene or other genes associated with increased risk of G6PD deficiency.\",\n \"about\": \"G6PD deficiency is a genetic disorder that occurs more commonly in males than in females. Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme that helps red blood cells work correctly. It also protects them from substances in the blood that could harm them. When there is not enough G6PD, red blood cells break down prematurely.\\n\\nAnemia develops when the body is unable to compensate for the accelerated loss of red blood cells. On the other hand, the deficiency of this enzyme alone is not sufficient to cause the loss of red blood cells (hemolysis); additional factors are needed to cause the progression of the disease. Triggers for this disease include certain infectious diseases, some drugs, and fava beans, which can cause potentially serious acute hemolytic anemia known as favism. \\n\\nIt is important to note that the majority of people with G6PD deficiency are healthy as long as the disease isn't triggered, and they generally go through life without any noticeable symptoms.\",\n \"caption\": \"Red blood cell health\",\n \"active_variants\": 0,\n \"GENES\": {\n \"G6PD\": {\n \"rs1050828\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Familial Hypercholesterolemia\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"Your genetic analysis show that you are less likely to have familial hypercholesterolemia. \",\n \"risk_management\": \"Having a low genetic predisposition to FH does not mean the total absence of the disease; it is still best to consult your doctor, especially if you experience any of the symptoms related to FH. \\n\\nYour doctor or healthcare provider may ask for a physical exam and ask questions about your personal and family medical history. If you have a strong family history of early heart attacks, your physician may have blood tests done to determine your cholesterol levels. \\n\\nHow well you do depends on how closely you follow the advice of your healthcare provider. Making dietary changes, exercising, and taking your medications properly can reduce your cholesterol levels. These changes can help delay a heart attack, particularly for people with relatively mild disorders.\",\n \"risk_factors\": [\n \"Both genetic and environmental risk factors can contribute to familial hypercholesterolemia. \",\n \"Lifestyle choices, which include diet, physical activity, and smoking, significantly influence the amount of cholesterol in the blood and the risk of coronary artery disease. \",\n \"Factors that affect the possible result of the condition include gender, age, and health concerns such as diabetes and obesity.\"\n ],\n \"signs_and_symptoms\": [\n \"People with prolonged high cholesterol levels may experience the followoing: \",\n \"Fatty skin deposits called xanthomas over parts of the hands, elbows, knees, ankles and around the cornea of the eye.\",\n \"Cholesterol deposits in the eyelids (xanthelasmas).\",\n \"Chest pain (angina) or other signs of coronary artery disease may be present at a young age.\",\n \"Cramping of one or both calves when walking.\",\n \"Sores on the toes that do not heal.\",\n \"Sudden stroke-like symptoms such as trouble speaking, drooping on one side of the face, weakness of an arm or leg, and loss of balance.\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Variants in the LDLR gene are the most common cause of this condition. Less commonly, familial hypercholesterolemia is caused by mutations in the APOB, LDLRAP1, or PCSK9 gene. We've analyzed several variants in LDLR and APOB to help you know where your risk for FH lies. \\n\\nThis test does not cover all possible variants in the present genes or other genes associated with increased risk of FH. A poor diet and unhealthy lifestyle can cause high cholesterol, even in those without this genetic predisposition. \",\n \"about\": \"Family hypercholesterolemia (FH) is a pervasive life-threatening genetic condition that causes increased levels of cholesterol. FH causes early heart attacks and heart disease when undiagnosed and unmanaged. The body requires this substance to create cell membranes, produce certain hormones, and produce compounds that aid in fat digestion. In people with familial hypercholesterolemia, the body is unable to dispose of extra cholesterol, and it builds up in the blood. Far too much cholesterol increases the likelihood of developing heart disease. \\n\\nOne in 250 adults has an FH genetic mutation, based on the 1999-2012 National Health and Nutrition Examination Survey (NHANES). Familial hypercholesterolemia may be inherited from one parent (heterozygous FH) or, in rare instances, from both parents (homozygous FH). Individuals with this more rare form of FH may have very high levels of LDL cholesterol. Others may need bypass surgery before they reach adulthood. People with homozygous FH rarely live past their 20s without treatment.\",\n \"caption\": \"Life-threatening cholesterol levels\",\n \"active_variants\": 0,\n \"GENES\": {\n \"LDLR\": {\n \"rs769446356\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB547\": {\n \"rs121908025\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB46\": {\n \"rs771019366\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB832\": {\n \"rs144172724\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB462\": {\n \"rs121908026\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB895\": {\n \"rs121908039\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB584\": {\n \"rs121908027\": {\n \"genotype\": \"II\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB350\": {\n \"rs373822756\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB819\": {\n \"rs121908029\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB231\": {\n \"rs139043155\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB574\": {\n \"rs140241383\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB428\": {\n \"rs730882096\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB391\": {\n \"rs137943601\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB720\": {\n \"rs28942078\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB809\": {\n \"rs139624145\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB609\": {\n \"rs28941776\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB276\": {\n \"rs137929307\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB727\": {\n \"rs775092314\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB415\": {\n \"rs121908031\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"LDLR@DUB260\": {\n \"rs28942084\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Transthyretin related Hereditary Amyloidosis\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"You may have a low risk of TTR-related amyloidosis.\",\n \"risk_management\": \"TTR-related amyloidosis is an inherited condition, so consult your doctor if you have a family history of this disorder. The onset of symptoms starts between ages 20 and 70. Diagnosis is determined by a combination of family history, examination of symptoms, biopsy of tissues, and the identification of TTR variants through other genetic tests.\",\n \"risk_factors\": [\n \"The following are the risk factors that can affect your risk of the disease:\",\n \"Age: Symptoms begin in adulthood.\",\n \"Sex: Some studies report that men are more likely to show symptoms than women.\",\n \"Race/Ethnicity: Some TTR-related amyloidosis variants are more common in certain ethnicities (e.g. Val122Ile in African Americans, Val30Met in Portuguese, Swedish, and Japanese people).\",\n \"Heredity: You are more likely to develop TTR-related amyloidosis if you have a family history of the condition.\"\n ],\n \"signs_and_symptoms\": [\n \"TTR-related amyloidosis can affect many organs and the symptoms depend on the organ affected. The organs include:\",\n \"Peripheral neuropathy (nerve damage).\",\n \"Autonomic neuropathy (disruption of automatic functions, such as the heart beat).\",\n \"Gastrointestinal impairment.\",\n \"Cardiomyopathy (heart damage).\",\n \"Nephropathy (kidney damage).\",\n \"Ocular deposition (blockages in the eyes).\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"The genetic variants used in this analysis are known mutations in the TTR gene and are significantly associated with TTR-related amyloidosis. The disorder is inherited in an autosomal dominant pattern. That means just one copy of the risk allele is enough to cause the condition.\\n\\nThis test does not cover all possible variants in the present gene associated with increased risk of Transthyretin-related Hereditary Amyloidosis.\",\n \"about\": \"Transthyretin-related Amyloidosis is a rare inherited condition characterized by the buildup of protein aggregates called \\\"amyloids\\\" in the organs and tissues. It is caused by mutations in the TTR gene, which produces the protein \\\"transthyretin.\\\" These mutations alter the structure of the protein, causing the formation of amyloids. The buildup forms fibrous deposits that affect the function of organs and tissues over time. This condition is slow and progressive, damaging the heart, nervous system, and other parts of the body.\",\n \"caption\": \"Abnormal protein buildup\",\n \"active_variants\": 0,\n \"GENES\": {\n \"TTR\\nVal122Ile\": {\n \"rs76992529\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"TTR\\nIle88Leu\": {\n \"rs121918085\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"TTR\\nThr60Ala\": {\n \"rs121918070\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"TTR\\nIle84Ser\": {\n \"rs121918072\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"MUTYH associated Polyposis\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"You may have a low risk of MUTYH-associated Polyposis.\",\n \"risk_management\": \"MUTYH-associated Polyposis is an inherited condition, so consult your doctor if you have a family history of this disorder. For patients at risk, a colonoscopy every six months or every year is recommended for surveillance and removal of suspicious polyps. An endoscopy may be recommended to check for manifestations outside the colon. \",\n \"risk_factors\": [\n \"Disease development has been largely influenced by: \",\n \"Heredity: You are more likely to develop MUTYH-associated polyposis if you have a family history of the condition.\",\n \"Age: The risk of MUTYH-associated Polyposis increases with age. The average age at the time of diagnosis among patients is 47 years. \",\n \"Chronic gastrointestinal diseases: Chronic bowel disorders, such as Crohn's disease and ulcerative colitis, can increase the risk of cancer.\",\n \"Ethnicity: A high percentage of colon cancer is observed among African Americans, while cases of rectal cancer are more common among Native Hawaiians, Japanese Americans, and Latinos. Also, some MUTYH-related polyposis variants are more common in certain ethnicities (e.g. Tyr179Cys and Gly396Asp in Caucasians/European-descent, and Glu466Ter in Asians).\",\n \"Lifestyle: Diet, smoking and alcohol abuse are linked to colorectal cancer.\"\n ],\n \"signs_and_symptoms\": [\n \"Major sign/symptom include: \",\n \"Multiple colorectal polyps\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"The genetic variants used in this analysis are known mutations in the MUTYH gene and are significantly associated with hereditary polyposis. The disorder is mainly inherited in an autosomal recessive pattern, which means two copies of the risk allele are required to cause the condition, although some reports suggest that one copy of the risk allele is enough for an increased risk of cancer.\\n\\nThis test does not cover all possible variants in the present gene associated with increased risk of MUTYH-associated Polyposis. Moreover, there are many causes of cancer, so a low risk of this disorder does not necessarily reduce your overall risk of cancer. Healthy lifestyle choices, such as limiting the use of alcohol and red meat, are crucial to the prevention of cancer. \",\n \"about\": \"MUTYH-associated Polyposis is a hereditary condition characterized by the development of colon and rectal polyps. This condition has a lifetime risk of colon cancer. Multiple polyps that develop in the colon are benign at first but can turn malignant, and therefore have an increased risk of cancer if the polyps are not removed. There is also some evidence that this condition has an increased risk of other malignancies, such as duodenal, breast, and endometrial cancers.\",\n \"caption\": \"Polyps that can lead to cancer\",\n \"active_variants\": 0,\n \"GENES\": {\n \"MUTYH\\nTyr179Cys/Tyr165Cys\": {\n \"rs34612342\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"MUTYH\\nGlu466Ter\": {\n \"rs121908381\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Hereditary Thrombophilia\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"You may have a low risk of hereditary thrombophilia.\",\n \"risk_management\": \"Hereditary thrombophilia is hard to diagnose, so consult your doctor if you have a family history of this disorder. Patients with this condition usually do not need treatment unless a blood clot occurs. In the general population, the risk of a blood clot is 1 in 1,000. If you have factor V Leiden thrombophilia, one copy of the risk allele has a chance of 3 to 8 in 1,000 to cause a blood clot. Two copies increase the risk to 80 in 1,000. \\n\\nOn the other hand, one copy of the risk allele in prothrombin thrombophilia has a chance of 2 to 3 in 1,000, while two copies may increase the risk to 20 in 1,000 for a blood clot. In case of a blood clot, anticoagulant medications are usually prescribed. Changing your lifestyle, such as lose weight if you are obese, stopping smoking, and have an active lifestyle, can reduce your risk of a blood clot.\",\n \"risk_factors\": [\n \"The following are certain risk factors that can increase the chance of a blood clot:\",\n \"Surgery\",\n \"Pregnancy\",\n \"Immobility\",\n \"Some cancer and cancer treatments\",\n \"Trauma\",\n \"Obesity\",\n \"Age\",\n \"Some birth control pills\",\n \"Smoking\"\n ],\n \"signs_and_symptoms\": [\n \"Most DVT patients do not show symptoms. \",\n \"A pain or discomfort may be felt in the legs, arms, chest, head, abdomen, or any parts of the body, depending on the location of the blood clot.\"\n ],\n \"star_rating\": 3,\n \"snp_table_caption\": \"Hereditary thrombophilia are most associated with the genetic variant in the F5 and F2 genes. The mutation in F5 gene causes factor V Leiden thrombophilia while the variant in F2 gene causes Prothrombin thrombophilia. The risk of developing blood clots depends on the number of risk alleles present in your genotype per variant.\\n\\nThis test does not cover all possible variants in the present genes or other genes associated with increased risk of Hereditary Thrombophilia. Blood clots may also be caused by many other factors, so even if you have a low risk of this particular condition, does not necessarily reduce the risk of blood clot caused by other conditions.\",\n \"about\": \"Hereditary Thrombophilia is a group of inherited conditions that form abnormal blood clots in the blood vessels. The most common thrombophilias are caused by mutations in the F5 and F2 genes, which cause a type of clotting called deep vein thrombosis (DVT). DVT usually starts from a vein in the legs, but the clots can break away and travel to the lungs, causing pulmonary embolism (clot in the lungs). It is a potentially life-threatening condition, usually presenting with no visible symptoms until the blood clot starts to cause severe problems.\",\n \"caption\": \"Abnormal blood clotting issue\",\n \"active_variants\": 0,\n \"GENES\": {\n \"F5\": {\n \"rs6025\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"F2\": {\n \"rs1799963\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n }\n }\n}"},{"id":"e67fa604-bab4-498a-97da-c38d5bc3b057","name":"Disease Report Invalid Partner ID/ Public Key/ Private Key","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1c2b7b12b289_709f9fd16bb5_8aafce768660\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/disease/report"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"0183b1c344f00068a80cf17cb7628f63\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"13e09045-b4d6-4a28-b848-c5e7e7ff1f3e"},{"key":"X-Runtime","value":"0.004456"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Partner Not Found\",\n \"report_json\": {}\n}"}],"_postman_id":"f71efa3e-4c41-41a4-a183-301bfca93fd3"},{"name":"COVID Report","id":"674dd4d0-f9c7-4792-a869-3ad565695fcb","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/covid/report","description":"

Description: This Endpoint generates/retrieves the latest covid-19 report for any customer

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

report_json

JSON

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mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"d9520a04fc0f2b749de7ac446e33d9cb\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"0184a8b7-77b7-4671-85bd-d46aa2b46de2"},{"key":"X-Runtime","value":"0.003532"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"400\",\n \"message\": \"Required parameter 'customer_id' missing\",\n \"report_json\": {}\n}"},{"id":"70490a6b-5ae7-4ec5-a0aa-5f317852dbe4","name":"COVID Report Successful Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1c2b7b12b289_709f9fd16bb5_8aafce768660\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/covid/report"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"5bf95fbb59cc6bb6db91714016a2b603\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"80ef5638-efed-42f0-aded-0d9a6669ab72"},{"key":"X-Runtime","value":"0.014144"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"COVID-19 Genetic Report Generated\",\n \"report_json\": {\n \"Predisposition to Coronavirus Infection\": {\n \"result_options\": [\n \"LOWER\",\n \"INTERMEDIATE\",\n \"HIGHER\"\n ],\n \"result\": \"LOWER\",\n \"result_description\": \"Based on your genetic analysis, you may have a lower risk of contracting COVID-19. \",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Genetic variation in host immunity has been previously considered a significant factor in identifying susceptibility to infectious diseases. This test covered selected variants that have been identified to affect host immune response to known infectious diseases. \\n\\nCertain polymorphisms in the α-2-Heremans-Schmid Glycoprotein (AHSG), 2',5'-oligoadenylate synthetase 1 (OAS1), and myxovirus resistance 1 (MxA) genes were associated with SARS infection. In addition, mannose-binding lectin (MBL) gene expression contributes to the first-line host defense against SARS-CoV, and MBL deficiency is a factor in SARS infection. \\n\\nPut simply, these genes affect how likely you are to be infected with certain viruses similar to COVID-19.\",\n \"about\": \"Genetic studies linking susceptibility or predisposition to COVID-19 infection are still limited. Previous studies on SARS and MERS have shown that a host of genetic factors may play a role in your response to coronavirus infection, as well as your risk of being infected. COVID-19 research reported that older, male patients, and those with pre-existing medical conditions, are at an increased risk for the development of the disease, but the extent to which genetic factors might influence susceptibility to SARS-CoV-2 infection remains unknown. \",\n \"caption\": \"Your Likelihood of Infection\",\n \"reference\": [\n \"1. Zhu, X., Wang, Y., Zhang, H., Liu, X., Chen, T., Yang, R., Shi, Y., Cao, W., Li, P., Ma, Q., Zhai, Y., He, F., Zhou, G., & Cao, C. (2011). Genetic variation of the human α-2-Heremans-Schmid glycoprotein (AHSG) gene associated with the risk of SARS-CoV infection. PloS one, 6(8), e23730. https://doi.org/10.1371/journal.pone.0023730\",\n \"2. He, J., Feng, D., de Vlas, S. J., Wang, H., Fontanet, A., Zhang, P., Plancoulaine, S., Tang, F., Zhan, L., Yang, H., Wang, T., Richardus, J. H., Habbema, J. D., & Cao, W. (2006). Association of SARS susceptibility with single nucleic acid polymorphisms of OAS1 and MxA genes: a case-control study. BMC infectious diseases, 6, 106. https://doi.org/10.1186/1471-2334-6-106\",\n \"3. Ching, J. C., Chan, K. Y., Lee, E. H., Xu, M. S., Ting, C. K., So, T. M., Sham, P. C., Leung, G. M., Peiris, J. S., & Khoo, U. S. (2010). Significance of the myxovirus resistance A (MxA) gene -123C>a single-nucleotide polymorphism in suppressed interferon beta induction of severe acute respiratory syndrome coronavirus infection. The Journal of infectious diseases, 201(12), 1899–1908. https://doi.org/10.1086/652799 \",\n \"4. Hamano, E., Hijikata, M., Itoyama, S., Quy, T., Phi, N. C., Long, H. T., Ha, L. D., Ban, V. V., Matsushita, I., Yanai, H., Kirikae, F., Kirikae, T., Kuratsuji, T., Sasazuki, T., & Keicho, N. (2005). Polymorphisms of interferon-inducible genes OAS-1 and MxA associated with SARS in the Vietnamese population. Biochemical and biophysical research communications, 329(4), 1234–1239. https://doi.org/10.1016/j.bbrc.2005.02.101 \",\n \"5. Ip, W. K., Chan, K. H., Law, H. K., Tso, G. H., Kong, E. K., Wong, W. H., To, Y. F., Yung, R. W., Chow, E. Y., Au, K. L., Chan, E. Y., Lim, W., Jensenius, J. C., Turner, M. W., Peiris, J. S., & Lau, Y. L. (2005). Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection. The Journal of infectious diseases, 191(10), 1697–1704. https://doi.org/10.1086/429631 \",\n \"6. Zhang, H., Zhou, G., Zhi, L., Yang, H., Zhai, Y., Dong, X., Zhang, X., Gao, X., Zhu, Y., & He, F. (2005). Association between mannose-binding lectin gene polymorphisms and susceptibility to severe acute respiratory syndrome coronavirus infection. The Journal of infectious diseases, 192(8), 1355–1361. https://doi.org/10.1086/491479 \"\n ],\n \"active_variants\": 1,\n \"GENES\": {\n \"OAS1\": {\n \"rs2660\": {\n \"genotype\": \"AG\",\n \"effect_allels\": 1\n }\n },\n \"MBL2\": {\n \"rs1800450\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Infection Severity\": {\n \"result_options\": [\n \"LOWER\",\n \"INTERMEDIATE\",\n \"HIGHER\"\n ],\n \"result\": \"INTERMEDIATE\",\n \"result_description\": \"You may have an intermediate risk for a severe clinical outcome with COVID-19, which means that you are more likely to experience moderate symptoms when infected with the virus.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"These genes are associated with severe acute respiratory syndrome. \\n\\nThe CD209 gene is involved in the recognition of many pathogens, including leprosy and tuberculosis mycobacteria, the Ebola, hepatitis C, HIV-1, and Dengue viruses, and the SARS-CoV acute respiratory syndrome coronavirus. Specifically, it can interact with the virus and subsequently conveys signals to your immune cells, which influences your immune response and clinical outcomes.\\n\\nThe ICAM3 gene is involved in immune signalling, specifically the T cell-mediated immune response. The ICAM3 protein interacts with the protein product of CD209 gene, which allows cell-to-cell engagement for the subsequent immune response to the SARS disease, and thus influences the severity of infection. This report also included the first robust genetic susceptibility loci in the leucine zipper transcription factor like 1 (LZTFL1) and ABO intron variant for the development of respiratory failure in COVID-19 patients. \\n\\nOther genes, IL18, IL1A and FGL2, are also involved in immune responses.\\n\\nThis test does not cover all possible variants associated with severe acute respiratory syndrome.\",\n \"about\": \"Different genetic variants play a role in the vulnerability of infection and the severity of the disease. Several genes have been associated with severe acute respiratory syndrome (SARS) caused by coronavirus infection. These are usually immune-related genes, and their role is significant to the immunopathogenesis (immunity) and clinical prognosis of the SARS disease.\",\n \"caption\": \"Your Reaction to Infection\",\n \"reference\": [\n \"1. Chan, K. Y. K., Xu, M. S., Ching, J. C. Y., So, T. M. K., Lai, S. T., Chu, C. M., ... & Lin, C. L. S. (2010). CD209 (DC-SIGN)− 336A> G promoter polymorphism and severe acute respiratory syndrome in Hong Kong Chinese. Human immunology, 71(7), 702-707.\",\n \"2. Chan, K. Y., Ching, J. C., Xu, M. S., Cheung, A. N., Yip, S. P., Yam, L. Y., ... & Huang, F. P. (2007). Association of ICAM3 genetic variant with severe acute respiratory syndrome. The Journal of infectious diseases, 196(2), 271-280. \",\n \"3. Ellinghaus, D., Degenhardt, F., Bujanda, L., Buti, M., Albillos, A., Invernizzi, P., . . . Karlsen, T. H. (2020). Genomewide Association Study of Severe Covid-19 with Respiratory Failure. New England Journal of Medicine. doi:10.1056/nejmoa2020283 \"\n ],\n \"active_variants\": 3,\n \"GENES\": {\n \"CD209\": {\n \"rs4804803\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 2\n }\n },\n \"ICAM3\": {\n \"rs2304237\": {\n \"genotype\": \"TC\",\n \"effect_allels\": 1\n }\n },\n \"IL18\": {\n \"rs1946518\": {\n \"genotype\": \"GT\",\n \"effect_allels\": 1\n }\n },\n \"IL1A\": {\n \"rs1800587\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"LZTFL1\": {\n \"rs10490770\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Reaction to Oseltamivir\": {\n \"result_options\": [\n \"LOWER\",\n \"INTERMEDIATE\",\n \"HIGHER\"\n ],\n \"result\": \"LOWER\",\n \"result_description\": \"You may have a lower risk of severe adverse reactions to Oseltamivir treatment.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"Genetic variants in the NEU2 and ABCB1 genes are linked with adverse reactions to Oseltamivir treatment. A variant in the NEU2 gene has been found to increase human sialidase binding affinity to Oseltamivir, which may cause adverse reactions to the drug. Meanwhile, variants in the ABCB1 gene have been suggested to increase the uptake of Oseltamivir in the brain, which should normally be limited and thus may cause adverse effects.\\n\\nIt has been found that the human NEU2 protein is similar to the viral neuraminidase (enzyme) that has been the target of Oseltamivir. Oseltamivir inhibits the neuraminidase activity of the influenza virus.\",\n \"about\": \"There are currently no specific drugs to treat the COVID-19 infection, and Oseltamivir is one of the medications that is currently being trialled to treat infected patients. Oseltamivir is an antiviral drug that was developed as a treatment for the influenza virus (flu). Some case reports have suggested the use of Oseltamivir, together with other antiviral drugs, in patients hospitalized due to COVID-19 in Wuhan, China. Currently, there is an ongoing interventional clinical trial to evaluate the effectiveness of Oseltamivir as part of the cocktail drugs to improve the clinical course of the disease. \\n\\nThis report does not suggest the use of Oseltamivir until further testing has been done. Rather, it may give insight into your potential risk for an adverse reaction to one particular drug, which, as of June 2020, has not been thoroughly tested for efficacy against COVID-19.\",\n \"caption\": \"Antiviral Drug\",\n \"reference\": [\n \"1. Li, C. Y., Yu, Q., Ye, Z. Q., Sun, Y., He, Q., Li, X. M., ... & Wei, L. (2007). A nonsynonymous SNP in human cytosolic sialidase in a small Asian population results in reduced enzyme activity: potential link with severe adverse reactions to Oseltamivir. Cell research, 17(4), 357-362.\",\n \"2. L’Huillier, A. G., Ing Lorenzini, K., Crisinel, P. A., Rebsamen, M. C., Fluss, J., Korff, C. M., ... & Desmeules, J. A. (2011). ABCB1 polymorphisms and neuropsychiatric adverse events in Oseltamivir-treated children during influenza H1N1/09 pandemia. Pharmacogenomics, 12(10), 1493-1501.\",\n \"3. Nakamura, K., Schwartz, B. S., Lindegårdh, N., Keh, C., & Guglielmo, B. J. (2010). Possible neuropsychiatric reaction to high-dose Oseltamivir during acute 2009 H1N1 influenza A infection. Clinical Infectious Diseases, 50(7), e47-e49.\"\n ],\n \"active_variants\": 0,\n \"GENES\": {\n \"ABCB1\": {\n \"rs1045642\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Reaction to Chloroquine\": {\n \"result_options\": [\n \"LOWER\",\n \"INTERMEDIATE\",\n \"HIGHER\"\n ],\n \"result\": \"LOWER\",\n \"result_description\": \"Based on your genetic analysis, you may have a lower risk of developing adverse effects from chloroquine treatment. \",\n \"star_rating\": 1,\n \"snp_table_caption\": \"CQ drug labels have warnings for use in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. People with G6PD deficiency are at risk for hemolytic anemia which can be triggered by infections, certain foods, or drugs. \\n\\nBecause of the interaction between CQ and the G6PD gene, the drug may have a negative impact on patients with certain variants of the gene.\\n\\nThis test does not cover all the possible variants found in the G6PD gene. \\n\",\n \"about\": \"Chloroquine was a popular treatment for malaria and amebiasis in the past. \\n\\nChloroquine (CQ) was also reported to effectively inhibit SARS-CoV- 2 infection in vitro. This drug was used in treating COVID-19 because of its availability, safety records, and relatively low costs. However, some researchers have reported its adverse effects on COVID-19 patients, especially to those cases that have been self-medicating. \",\n \"caption\": \"Malaria Treatment\",\n \"reference\": [\n \"1, Liu, J., Cao, R., Xu, M. et al. (2020). Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro. Cell Discov 6, 16. https://doi.org/10.1038/s41421-020-0156-0 \",\n \"2. da Rocha, J., Othman, H., Tiemessen, C. T., Botha, G., Ramsay, M., Masimirembwa, C., Adebamowo, C., Choudhury, A., Brandenburg, J. T., Matshaba, M., Simo, G., Gamo, F. J., & Hazelhurst, S. (2020). G6PD variant distribution in sub-Saharan Africa and potential risks of using chloroquine/Hydroxychloroquine based treatments for COVID-19. medRxiv : the preprint server for health sciences, 2020.05.27.20114066. https://doi.org/10.1101/2020.05.27.20114066 \",\n \"3. McDonagh, E. M., Thorn, C. F., Bautista, J. M., Youngster, I., Altman, R. B., & Klein, T. E. (2012). PharmGKB summary: very important pharmacogene information for G6PD. Pharmacogenetics and genomics, 22(3), 219–228. https://doi.org/10.1097/FPC.0b013e32834eb313 \",\n \"4. Relling, M. V., McDonagh, E. M., Chang, T., Caudle, K. E., McLeod, H. L., Haidar, C. E., Klein, T., Luzzatto, L., & Clinical Pharmacogenetics Implementation Consortium. (2014). Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for rasburicase therapy in the context of G6PD deficiency genotype. Clinical pharmacology and therapeutics, 96(2), 169–174. https://doi.org/10.1038/clpt.2014.97 \",\n \"5. Wang, L.-Y., Cui, J.-J., OuYang, Q.-Y., Zhan, Y., Wang, Y.-M., Xu, X.-Y., Guo, C.-X., & Yin, J. (2020). Genetic Profiles in Pharmacogenes Indicate Personalized Drug Therapy for COVID-19. Medrxiv, 0. https://doi.org/10.1101/2020.03.23.20041350\"\n ],\n \"active_variants\": 0,\n \"GENES\": {\n \"G6PD\": {\n \"rs1050828\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"G6PD@DUB6\": {\n \"rs5030868\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"G6PD@DUB375\": {\n \"rs5030869\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"G6PD@DUB722\": {\n \"rs72554665\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"G6PD@DUB334\": {\n \"rs78478128\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Response to Hydroxychloroquine\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"LOW\",\n \"result_description\": \"You may have a low concentration of Hydroxychloroquine in blood. This means that the drug may be less bioavailable in your body. \",\n \"star_rating\": 1,\n \"snp_table_caption\": \"The genetic variants used in this report are found in the CYP2D6 gene. This gene encodes the enzyme that is mainly responsible for drug clearance. It is involved in the metabolism of around 25% of clinically used drugs, including Hydroxychloroquine. Basically, this gene affects how well your body uses this drug.\\n\\nThe drug is metabolized into \\\"N-desethyl Hydroxychloroquine,\\\" which is the activated form of the medication. Studies show that polymorphisms in the CYP2D6 gene are associated with the levels of converted N-desethyl Hydroxychloroquine, which may give some insight into your response to the drug.\",\n \"about\": \"Hydroxychloroquine is another form of chloroquine which is used for the treatment of malaria and rheumatic diseases, such as systemic lupus erythematosus and rheumatoid arthritis. It is also one of the most popular drugs being used to treat COVID-19 patients. Some studies have demonstrated its efficacy against the novel coronavirus, and others have shown that it can lower the mortality rate of hospitalized patients.\\n\\nPotential pharmacokinetic effects of Hydroxychloroquine should be considered. This report may give insight into the potential effect your body may have on the drug when administered. We do not suggest the use of Hydroxychloroquine unless prescribed by the attending physician.\",\n \"caption\": \"Side Effects & Risk\",\n \"reference\": [\n \"1. Gautret, P., Lagier, J. C., Parola, P., Meddeb, L., Mailhe, M., Doudier, B., ... & Honoré, S. (2020). Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. International journal of antimicrobial agents, 105949.\",\n \"2. Fanin, A., Calegari, J., Beverina, A., Tiraboschi, S., & di Autoformazione Metodologica, G. (2020). Hydroxychloroquine and azithromycin as a treatment of COVID-19. Internal and Emergency Medicine, 1.\",\n \"3. Arshad, S., Kilgore, P., Chaudhry, Z. S., Jacobsen, G., Wang, D. D., Huitsing, K., ... & O’Neill, W. (2020). Treatment with Hydroxychloroquine, Azithromycin, and Combination in Patients Hospitalized with COVID-19. International Journal of Infectious Diseases.\",\n \"4. Lee, J. Y., Vinayagamoorthy, N., Han, K., Kwok, S. K., Ju, J. H., Park, K. S., ... & Park, S. H. (2016). Association of polymorphisms of cytochrome P450 2D6 with blood Hydroxychloroquine levels in patients with systemic lupus erythematosus. Arthritis & Rheumatology, 68(1), 184-190.\"\n ],\n \"active_variants\": 0,\n \"GENES\": {\n \"CYP2D6@DUB481\": {\n \"rs1135840\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Response to Lopinavir\": {\n \"result_options\": [\n \"LOW\",\n \"INTERMEDIATE\",\n \"HIGH\"\n ],\n \"result\": \"HIGH\",\n \"result_description\": \"You may have a high initial inactivation and clearance of Lopinavir. This means that you have a lower bioavailability of the drug or that lower amounts of the drug reach your blood circulation. A repeated dose may be needed earlier than usual to maintain optimal drug concentration in the blood.\",\n \"star_rating\": 1,\n \"snp_table_caption\": \"The genetic variant that is used in this test is found in the SLCO1B1 gene. This gene is a member of SLCO gene family that encodes transport proteins which react with numerous drugs and compounds. \\n\\nLopinavir and other protease inhibitors have been reported to be affected by SLCO1B1, thus making the gene an important factor of drug uptake. Studies show that genetic variants in the SLCO1B1 gene influence the drug clearance of Lopinavir in HIV-infected patients.\",\n \"about\": \"Lopinavir is an antiviral drug used for the treatment of Human Immunodeficiency Virus (HIV). It is also one of the medications that is being repurposed for the treatment of COVID-19 while waiting for the development of a drug that can actually cure the disease. As a protease inhibitor, this drug may potentially inhibit the coronavirus's genetic material to prevent its replication. Studies suggest that Lopinavir, coupled with another drug Ritonavir, may be associated with a lower risk of severe clinical outcomes and mortality in COVID-19 patients. \\n\\nThe potential pharmacokinetic effects of Lopinavir-Ritonavir should be considered. This report may give insight into the potential effect your body may have on the drug when administered. We do not suggest the use of Lopinavir-Ritonavir unless prescribed by the attending physician.\",\n \"caption\": \"HIV Drug\",\n \"reference\": [\n \"1. Kohlrausch, F. B., de Cássia Estrela, R., Barroso, P. F., & Suarez‐Kurtz, G. (2010). The impact of SLCO1B1 polymorphisms on the plasma concentration of Lopinavir and ritonavir in HIV‐infected men. British journal of clinical pharmacology, 69(1), 95-98.\",\n \"2. Lubomirov, R., di Iulio, J., Fayet, A., Colombo, S., Martinez, R., Marzolini, C., ... & Ledergerber, B. (2010). ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent Lopinavir coformulated with ritonavir. Pharmacogenetics and genomics, 20(4), 217-230.\",\n \"3. Dragović, G., Dimitrijević, B., Kušić, J., Soldatović, I., Jevtović, D., Olagunju, A., & Owen, A. (2020). Influence of SLCO1B1 polymorphisms on Lopinavir Ctrough in Serbian HIV/AIDS patients. British Journal of Clinical Pharmacology.\"\n ],\n \"active_variants\": 1,\n \"GENES\": {\n \"SLCO1B1\": {\n \"rs4149056\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 2\n }\n }\n }\n }\n }\n}"},{"id":"a210c1d0-1130-484b-aa6d-246b930a5efd","name":"COVID Report Customer Not Found Response","originalRequest":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_1c2b7b12b289_709f9fd16bb5_8aafce768660\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/covid/report"},"status":"OK","code":200,"_postman_previewlanguage":"json","header":[{"key":"X-Frame-Options","value":"SAMEORIGIN"},{"key":"X-XSS-Protection","value":"1; mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"26e867123861862d0a6e368c4731295d\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"c06793c1-8670-4d11-b2cb-187ebec43af8"},{"key":"X-Runtime","value":"0.005786"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"404\",\n \"message\": \"Customer Not Found\",\n \"report_json\": {}\n}"}],"_postman_id":"674dd4d0-f9c7-4792-a869-3ad565695fcb"},{"name":"Carrier Report","id":"548e9d4a-ca74-4925-bee8-8fd0cddcfcf5","protocolProfileBehavior":{"disableBodyPruning":true},"request":{"method":"GET","header":[],"body":{"mode":"raw","raw":"{\r\n \"public_key\":\"{{partner_public_key}}\", //Required\r\n \"partner_id\": \"{{partner_id}}\", //Required\r\n \"customer_id\": \"cus_e8eb752b8cd5_ae1977ded026_2a62493df984\" //Required\r\n}","options":{"raw":{"language":"json"}}},"url":"{{base_url}}/request/carrier/report","description":"

Description: This Endpoint generates/retrieves the latest carrier report for any customer

Request Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter	Required/Optional	Type
public_key	Required	String
partner_id	Required	String
customer_id	Required	String

Response Parameters:

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n

Parameter

Type

Note

status

int

200 For Success

4xx for errors

message

String

report_json

JSON

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mode=block"},{"key":"X-Content-Type-Options","value":"nosniff"},{"key":"X-Download-Options","value":"noopen"},{"key":"X-Permitted-Cross-Domain-Policies","value":"none"},{"key":"Referrer-Policy","value":"strict-origin-when-cross-origin"},{"key":"Content-Type","value":"application/json; charset=utf-8"},{"key":"ETag","value":"W/\"6470a7924d6acfc8802be69169b4073d\""},{"key":"Cache-Control","value":"max-age=0, private, must-revalidate"},{"key":"X-Request-Id","value":"1bcb1cd3-b5e4-4625-beee-edf8599b221d"},{"key":"X-Runtime","value":"0.017482"},{"key":"Transfer-Encoding","value":"chunked"}],"cookie":[],"responseTime":null,"body":"{\n \"status\": \"200\",\n \"message\": \"Carrier Report Generated\",\n \"report_json\": {\n \"Sickle Cell Disease and Other Hemoglobanopathies\": {\n \"result_options\": [\n \"0 Genetic Variant\",\n \"1 Genetic Variant\",\n \"2 or more Genetic Variants\"\n ],\n \"result\": \"0 Genetic Variant\",\n \"result_description\": \"Your analysis shows that you have no causal variant/s, which means you are not a carrier of a hemoglobinopathy disease.\",\n \"risk_management\": \"Treatments include generally managing the symptoms. Red blood cell transfusion may be necessary, especially during severe complications. Medication such as hydroxyurea is routinely used, and transplantations are also being explored. \\n\\nIf a variant is detected in your genome or you suspect yourself to be a carrier due to family history, consult a healthcare professional for follow-up tests. You should also consider genetic counseling if you are planning to start a family with your partner, especially if you have a strong family history. \",\n \"risk_factors\": {\n \"Age of Onset\": \" Newborns are usually asymptomatic and only start presenting symptoms later in infancy or early childhood. \",\n \"Ethnicities\": \" Sickle cell trait is most prevalent in the African ancestry. It is also common in the Mediterranean, Middle Eastern, Indian, Caribbean, and Central and South American populations. Beta Thalassemia is widespread in these populations as well, including Central and Southeast Asian populations.\",\n \"Heredity\": \" Individuals with a family history of these blood disorders are more likely to develop the disease. \"\n },\n \"signs_and_symptoms\": \"Symptoms may vary from person to person. These include shortness of breath, anemia, episodes of pain, swelling of hands and feet, jaundice, infectious diseases, and even organ damage.\\n\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"The HBB gene is involved in multiple blood disorders. It synthesizes the beta-globin, a subunit of hemoglobin. Mutations in this gene produce abnormal hemoglobin and, in turn, abnormal red blood cells. Without functional hemoglobin, the cells in the blood cannot efficiently deliver oxygen throughout the body. \",\n \"about\": \"Hemoglobinopathies, including Sickle Cell Disease and Beta Thalassemia, are a group of genetically inherited disorders that affects hemoglobin in red blood cells. It is characterized by either abnormal structure or production of the hemoglobin protein, both of which cause anemia. Differential severity of anemia can be seen across affected individuals. Around 1,100 infants are born with SCD every year in the US. The disease occurs in 1 in 300-500 African Americans and about 1 in 1,400 Hispanic Americans. \",\n \"caption\": \"Hemoglobin-related blood disorders\",\n \"test_interpretation\": \"Interpretation:\\n\\nSCD or β thalassemia only develops if a person has two copies of a genetic variant in the HBB gene. Having just one copy only makes a person a carrier.\\n\\nNo genetic variants detected for this test mean that there is a greater chance that you are not a carrier for a mutation. But it does not completely eliminate the probability of still being a carrier, especially if you belong to the most commonly affected ethnicities. Having one or more variants detected means that you are a carrier of the mutated variant associated with these blood disorders. \\n\\nLimitations:\\n\\nThis tests for a subset of variants that cause SCD or β thalassemia. However, this does not test for all possible variants in the HBB gene. Furthermore, this test does not diagnose you for blood disorders, nor does it offer any medical solutions. \",\n \"main_genes\": \"HBB\",\n \"reference\": [\n \"1. Carlice-dos-Reis, T., Viana, J., Moreira, F. C., Cardoso, G. L., Guerreiro, J., Santos, S., & Ribeiro-dos-Santos, Â. (2017). Investigation of mutations in the HBB gene using the 1,000 genomes database. PLOS ONE, 12(4), e0174637. https://doi.org/10.1371/journal.pone.0174637\",\n \"2. Bender, M. A. (2003). Sickle Cell Disease. In M. P. Adam (Eds.) et. al., GeneReviews®. University of Washington, Seattle.\",\n \"3. Powars, D. R., Chan, L. S., Hiti, A., Ramicone, E., & Johnson, C. (2005). Outcome of Sickle Cell Anemia: a 4-decade observational study of 1056 patients. Medicine, 84(6), 363–376. https://doi.org/10.1097/01.md.0000189089.45003.52\",\n \"4. Alanazi, M., Abduljaleel, Z., Khan, W., Warsy, A. S., Elrobh, M., Khan, Z., Amri, A. A., & Bazzi, M. D. (2011). In Silico Analysis of Single Nucleotide Polymorphism (SNPs) in Human β-Globin Gene. PLoS ONE, 6(10), e25876. https://doi.org/10.1371/journal.pone.0025876\",\n \"5. Origa, R. (2000). Beta-Thalassemia. In M. P. Adam (Eds.) et. al., GeneReviews®. University of Washington, Seattle.\",\n \"6. Gonzalez-Redondo, J. M., Stoming, T. A., Lanclos, K. D., Gu, Y. C., Kutlar, A., Kutlar, F., Nakatsuji, T., Deng, B., Han, I. S., & McKie, V. C. (1988). Clinical and genetic heterogeneity in black patients with homozygous beta-thalassemia from the southeastern United States. Blood, 72(3), 1007–1014.\",\n \"7. Traivaree, C., Monsereenusorn, C., Rujkijyanont, P., Prasertsin, W., & Boonyawat, B. (2018). Genotype-phenotype correlation among beta-thalassemia and beta-thalassemia/HbE disease in Thai children: predictable clinical spectrum using genotypic analysis. Journal of Blood Medicine, Volume 9, 35–41. https://doi.org/10.2147/jbm.s159295\",\n \"8. Gonzalez-Redondo, J. M., Kutlar, F., Kutlar, A., Stoming, T. A., Pablos, J. M. A., Kilinç, Y., & Huisman, T. H. J. (1988). Hb S(C)-β+-thalassaemia: different mutations are associated with different levels of normal Hb A. British Journal of Haematology, 70(1), 85–89. https://doi.org/10.1111/j.1365-2141.1988.tb02438.x\"\n ],\n \"GENES\": {\n \"HBB\": {\n \"rs334\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"HBB@DUB358086ceac79e\": {\n \"rs34598529\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"HBB@DUB503974a258b62\": {\n \"rs34690599\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"HBB@DUB60239c1e1ae96\": {\n \"rs34451549\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"HBB@DUB5392452558af\": {\n \"rs35004220\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HBB@DUB388705fbf9bab\": {\n \"rs35724775\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"HBB@DUB552c8e0f3c745\": {\n \"rs33915217\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HBB@DUB552139f4f944c\": {\n \"rs11549407\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"HBB@DUB166a4133f9077\": {\n \"rs63750783\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Cystic Fibrosis\": {\n \"result_options\": [\n \"0 Genetic Variant\",\n \"1 Genetic Variant\",\n \"2 or more Genetic Variants\"\n ],\n \"result\": \"0 Genetic Variant\",\n \"result_description\": \"Your analysis shows that you have no causal variant/s, which means you are not a carrier of CF. \",\n \"risk_management\": \"There is no known cure for Cystic Fibrosis, but drugs known as CFTR potentiators work by improving the function of the impaired protein. Response to such drugs can be selective to certain mutations that cause CF. Other treatments that manage the symptoms include bronchodilators, mucus thinners, anti-inflammatories, antibiotics, or surgery for more advanced conditions. \\n\\nIf a variant is detected in your genome or you suspect yourself to be a carrier due to family history, consult a healthcare professional for follow-up tests. You should also consider genetic counseling if you are planning to start a family with your partner, especially if you have a strong family history. \",\n \"risk_factors\": {\n \"Age of Onset\": \" From infancy \",\n \"Ethnicities\": \" CF affects all races but is very common in Ashkenazi Jewish and Caucasian populations. \",\n \"Heredity\": \" Individuals with a family history of CF are more likely to develop the disease. \"\n },\n \"signs_and_symptoms\": \"Symptoms may differ from person to person, and it may range from few signs to life-threatening complications. It affects many organs but most notably manifests in the lungs. Typical symptoms include chronic coughing, wheezing, clubbing of fingers, salty sweat, respiratory infections, blockage of the intestine, jaundice, malnutrition, and male infertility. CF is a progressive disease, and without proper management of symptoms, it may lead to respiratory failure and other fatal complications. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"The CFTR or Cystic-fibrosis-transmembrane-conductance-regulator gene is responsible for CF. This gene encodes for a protein that functions as a chloride channel in cells to help regulate the production of mucus, sweat, and digestive enzymes. Mutations in this gene create a faulty protein that produces thick, sticky mucus, which can lead to blockages in the lungs and other organs. \",\n \"about\": \"Cystic Fibrosis (CF) is a genetic disorder that is characterized by abnormal mucus production in the lungs and digestive system. It is one of the most commonly inherited diseases in the caucasian population, with an incidence of 1 in 2,500. Life span and survival rates have increased immensely, since it was first discovered, due to progression in the management of symptoms.\",\n \"caption\": \"Thick and sticky mucus \",\n \"test_interpretation\": \"Interpretation:\\n\\nCystic Fibrosis only manifests if a person has two copies of a genetic variant in the CFTR gene. Having just one copy only makes a person a carrier.\\n\\nNo genetic variants detected for this test mean that there is a greater chance that you are not a carrier for a CF mutation. But it does not completely eliminate the probability of still being a carrier, especially if you belong to the most commonly affected ethnicities. Having one or more variants detected means that you are a carrier of the mutated variant associated with Cystic Fibrosis. \\n\\nLimitations:\\n\\nThis tests for a subset of variants that cause Cystic Fibrosis. However, this does not test for all possible variants in the CFTR gene. Furthermore, this test does not diagnose you for Cystic Fibrosis, nor does it offer any medical solutions. \",\n \"main_genes\": \"CFTR\",\n \"reference\": [\n \"1.\\tPereira, S. V.-N., Ribeiro, J. D., Ribeiro, A. F., Bertuzzo, C. S., & Marson, F. A. L. (2019). Novel, rare and common pathogenic variants in the CFTR gene screened by high-throughput sequencing technology and predicted by in silico tools. Scientific Reports, 9, 6234. https://doi.org/10.1038/s41598-019-42404-6\",\n \"2.\\tOsborne, L., Santis, G., Schwarz, M., Klinger, K., Dörk, T., McIntosh, I., Schwartz, M., Nunes, V., Macek, M., Reiss, J., Highsmith, W. E., McMahon, R., Novelli, G., Malik, N., Bürger, J., Anvret, M., Wallace, A., Williams, C., Mathew, C., … Knight, R. A. (1992). Incidence and expression of the N1303K mutation of the cystic fibrosis (CFTR) gene. Human Genetics, 89(6), 653–658. https://doi.org/10.1007/bf00221957\",\n \"3.\\tAl-abadi, B., Al-hiary, M., Khasawneh, R., momani, A., Salameh, A., Saeidat, S., khlaifat, A., & alsondos, O. (2019). Cystic Fibrosis Gene Mutation Frequency Among a Group of Suspected Children in King Hussein Medical Center. Medical Archives, 73(2), 118. https://doi.org/10.5455/medarh.2019.73.118-120\",\n \"4.\\tNemeti, M., Johnson, J. P., Papp, Z., & Louie, E. (1992). The occurrence of various non-deltaF508 CFTR gene mutations among Hungarian cystic fibrosis patients. Human Genetics, 89(2), 245–246. https://doi.org/10.1007/bf00217133\",\n \"5.\\tWatson, M. S., Cutting, G. R., Desnick, R. J., Driscoll, D. A., Klinger, K., Mennuti, M., Palomaki, G. E., Popovich, B. W., Pratt, V. M., Rohlfs, E. M., Strom, C. M., Richards, C. S., Witt, D. R., & Grody, W. W. (2004). Cystic fibrosis population carrier screening: 2004 revision of American College of Medical Genetics mutation panel. Genetics in Medicine, 6(5), 387–391. https://doi.org/10.1097/01.gim.0000139506.11694.7c\",\n \"6.\\tOng, T., Marshall, S., Karkcezki, B., Sternen, D., Cheng, E., Cutting, G. (2001). Cystic Fibrosis and Congenital Absence of the Vas Deferens. In M. P. Adam (Eds.) et. al., GeneReviews®. University of Washington, Seattle.\"\n ],\n \"GENES\": {\n \"CFTR\": {\n \"rs113993960 \": {\n \"genotype\": \"II\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB38148b2df0e3b\": {\n \"rs113993959 \": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB2771974331de\": {\n \"rs80034486 \": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB619f041f5a3e3\": {\n \"rs74767530 \": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB979471d22b6de\": {\n \"rs121909011 \": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB81972ea4d86c9\": {\n \"rs77010898 \": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB8356fec0306c8\": {\n \"rs74597325 \": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB3552ee9c1001e\": {\n \"rs75961395 \": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB103cb4a15b3ba\": {\n \"rs74551128 \": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB2488f1827b947\": {\n \"rs78655421\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB780c40c2768fd\": {\n \"rs76713772 \": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB75fe4ae178c5\": {\n \"rs78756941\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"CFTR@DUB5015918f12e19\": {\n \"rs75527207\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Tay-Sachs Disease\": {\n \"result_options\": [\n \"0 Genetic Variant\",\n \"1 Genetic Variant\",\n \"2 or more Genetic Variants\"\n ],\n \"result\": \"0 Genetic Variant\",\n \"result_description\": \"Your analysis shows that you have no causal variant/s, which means you are not a carrier of TSD. \",\n \"risk_management\": \"Tay-Sachs disease is currently not curable, but treatments to manage the symptoms are given to the patients. These include managing seizures, treating infectious diseases, supporting adequate nutrition, and maximizing function through the services of physical, occupational, and speech therapists. \\n\\nIf a variant is detected in your genome or you suspect yourself to be a carrier due to family history, consult a healthcare professional for follow-up tests. You should also consider genetic counseling if you are planning to start a family with your partner, especially if you have a strong family history.\",\n \"risk_factors\": {\n \"Age of Onset\": \" Onset varies depending on the clinical forms of the disease, with the most severe presenting at 3 to 6 months of age. Others do not manifest it until 2 to 5 years old, while a later onset only presents during teenage years or young adulthood. \",\n \"Ethnicities\": \" TSD is most prevalent in Ashkenazi Jewish populations, but it is also common in individuals of French-Canadian and Cajun descent. \",\n \"Heredity\": \" Individuals with a family history of TSD are more likely to develop the disease. \"\n },\n \"signs_and_symptoms\": \"TSD symptoms may slightly vary among the three clinical forms of the disease. But all forms include symptoms such as loss of motor skills and coordination, muscle weakness, seizures, impaired speech and cognitive function, and loss of vision. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"The HEXA gene codes for a subunit of beta-hexosaminidase A, an enzyme found in structures called lysosomes inside the cells. The enzyme is an integral part of breaking down fatty substances called GM2 gangliosides. Mutations in the HEXA gene may result in absent or overly reduced amounts of the enzyme. As a consequence, GM2 gangliosides accumulate at excessive levels, which lead to destruction, particularly of neurons in the brain and spinal cord. \",\n \"about\": \"Tay-Sachs Disease (TSD) is a neurodegenerative inherited disorder characterized by a progressive decline of motor skills, muscle weakness, and impaired intellectual ability. This disease is associated with the continuous destruction of neurons in the central nervous system. Severity, onset, and life expectancy differ among its three clinical forms: infantile, juvenile, and late-onset. Incidence for this disease is more prevalent in the Ashkenazi Jewish population, estimated at 1 in 3,600 births and a 1 in 30 mutation carrier rate. \",\n \"caption\": \"Loss of motor skills\",\n \"test_interpretation\": \"Interpretation:\\n\\nTay-Sachs disease only manifests if a person has two copies of a genetic variant in the HEXA gene. Having just one copy only makes a person a carrier.\\n\\nNo genetic variants detected for this test mean that there is a greater chance that you are not a carrier for a TSD mutation. But it does not completely eliminate the probability of still being a carrier, especially if you belong to the most commonly affected ethnicities. Having one or more variants detected means that you are a carrier of the mutated variant associated with TSD. \\n\\nLimitations:\\n\\nThis tests for a subset of variants that cause Tay-Sachs disease. However, this does not test for all possible variants in the HEXA gene. Furthermore, this test does not diagnose you for Tay-Sachs disease, nor does it offer any medical solutions. \",\n \"main_genes\": \"HEXA\",\n \"reference\": [\n \"1.\\tHoffman, J. D., Greger, V., Strovel, E. T., Blitzer, M. G., Umbarger, M. A., Kennedy, C., Bishop, B., Saunders, P., Porreca, G. J., Schienda, J., Davie, J., Hallam, S., & Towne, C. (2013). Next‐generation DNA sequencing of HEXA: a step in the right direction for carrier screening. Molecular Genetics & Genomic Medicine, 1(4), 260–268. https://doi.org/10.1002/mgg3.37\",\n \"2.\\tMontalvo, A. L. E., Filocamo, M., Vlahoviček, K., Dardis, A., Lualdi, S., Corsolini, F., Bembi, B., & Pittis, M. G. (2005). Molecular analysis of the HEXA gene in Italian patients with infantile and late Onset Tay-Sachs disease: detection of fourteen novel alleles. Human Mutation, 26(3), 282. https://doi.org/10.1002/humu.9363\",\n \"3.\\tPark, N. J., Morgan, C., Sharma, R., Li, Y., Lobo, R. M., Redman, J. B., Salazar, D., Sun, W., Neidich, J. A., & Strom, C. M. (2010). Improving Accuracy of Tay Sachs Carrier Screening of the Non-Jewish Population: Analysis of 34 Carriers and Six Late-Onset Patients With HEXA Enzyme and DNA Sequence Analysis. Pediatric Research, 67(2), 217–220. https://doi.org/10.1203/pdr.0b013e3181c6e318\",\n \"4.\\tOhno, K., Saito, S., Sugawara, K., & Sakuraba, H. (2008). Structural consequences of amino acid substitutions causing Tay–Sachs disease. Molecular Genetics and Metabolism, 94(4), 462–468. https://doi.org/10.1016/j.ymgme.2008.04.006\",\n \"5.\\tToro, C., Marshall, S., Shirvan, L., D., Tifft, C., (1999). HEXA Disorders. In M. P. Adam (Eds.) et. al., GeneReviews®. University of Washington, Seattle.\"\n ],\n \"GENES\": {\n \"HEXA\": {\n \"rs387906309\": {\n \"genotype\": \"DD\",\n \"effect_allels\": 0\n }\n },\n \"HEXA@DUB19059915f7096\": {\n \"rs147324677\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HEXA@DUB598678d850c9c\": {\n \"rs76173977 \": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HEXA@DUB4658f9fb7e225\": {\n \"rs28942071\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"HEXA@DUB8974c3fdb8f26\": {\n \"rs121907956\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"HEXA@DUB1817a8586260f\": {\n \"rs138058578\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Canavan Disease\": {\n \"result_options\": [\n \"0 Genetic Variant\",\n \"1 Genetic Variant\",\n \"2 or more Genetic Variants\"\n ],\n \"result\": \"0 Genetic Variant\",\n \"result_description\": \"Your analysis shows that you have no causal variant/s, which means you are not a carrier of CD. \",\n \"risk_management\": \"There is no cure for Canavan disease, but management of symptoms is necessary to support survival. These include controlling seizures and infectious diseases and providing functional support through physical and speech therapies. \\n\\nIf a variant is detected in your genome or you suspect yourself to be a carrier due to family history, consult a healthcare professional for follow-up tests. You should also consider genetic counseling if you are planning to start a family with your partner, especially if you have a strong family history.\",\n \"risk_factors\": {\n \"Age of Onset\": \" The infantile form of CD starts to manifest by 3 to 5 months of age while the juvenile presents at the age of 4 to 5 years. \",\n \"Ethnicities\": \" CD is predominant in the people of Ashkenazi Jewish descent, but it can affect any ethnicity. \",\n \"Heredity\": \" Individuals with a family history of CD are more likely to develop the disease. \"\n },\n \"signs_and_symptoms\": \"Early signs of CD consist of irritability, decreased muscle tone, and head lag. Other symptoms include macrocephaly, developmental delay, seizures, and swallowing difficulties. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"The ASPA gene is responsible for the expression of an important enzyme in the brain called aspartoacylase. ASPA breaks down a compound called N-acetyl-L-aspartic acid (NAA) that is mostly found in brain neurons. In CD, loss or abnormal production of ASPA, caused by mutations in the gene, leads to a toxic build-up of NAA in the brain. \",\n \"about\": \"Canavan Disease (CD) is a neurodegenerative condition that belongs to the group of disorders known as leukodystrophies. CD is characterized by swelling and spongy degeneration of the white matter in the brain, and typical presentations include macrocephaly and psychomotor delay. The infantile and juvenile are the two clinical forms of the disease, with the former being the most common and severe. The incidence of this disorder is rare, and it is most prevalent in the Ashkenazi Jewish people, affecting 1 in 6,400 to 13,500 of the population. \",\n \"caption\": \"Degeneration of brain white matter\",\n \"test_interpretation\": \"Interpretation:\\n\\nCanavan disease only manifests if a person has two copies of a genetic variant in the ASPA gene. Having just one copy only makes a person a carrier.\\n\\nNo genetic variants detected for this test mean that there is a greater chance that you are not a carrier for a CD mutation. But it does not completely eliminate the probability of still being a carrier, especially if you belong to the most commonly affected ethnicities. Having one or more variants detected means that you are a carrier of the mutated variant associated with CD. \\n\\nLimitations:\\n\\nThis tests for a subset of variants that cause Canavan disease. However, this does not test for all possible variants in the ASPA gene. Furthermore, this test does not diagnose you for Canavan disease, nor does it offer any medical solutions. \",\n \"main_genes\": \"ASPA\",\n \"reference\": [\n \"1.\\tKaul, R., Gao, G. P., Aloya, M., Balamurugan, K., Petrosky, A., Michals, K., & Matalon, R. (1994). Canavan disease: mutations among Jewish and non-Jewish patients. American journal of human genetics, 55(1), 34–41.\",\n \"2.\\tKaul, R., Gao, G. P., Matalon, R., Aloya, M., Su, Q., Jin, M., Johnson, A. B., Schutgens, R. B., & Clarke, J. T. (1996). Identification and expression of eight novel mutations among non-Jewish patients with Canavan disease. American journal of human genetics, 59(1), 95–102.\",\n \"3.\\tYaron, Y., Schwartz, T., Mey-Raz, N., Amit, A., Lessing, J. B., & Malcov, M. (2005). Preimplantation Genetic Diagnosis of Canavan Disease. Fetal Diagnosis and Therapy, 20(5), 465–468. https://doi.org/10.1159/000086834\",\n \"4.\\tMatalon, R. (1997). Canavan Disease: Diagnosis and Molecular Analysis. Genetic Testing, 1(1), 21–25. https://doi.org/10.1089/gte.1997.1.21\",\n \"5.\\tMatalon, R., Delgado, L., Michals-Matalon, K. (1999). Canavan Disease. In M. P. Adam (Eds.) et. al., GeneReviews®. University of Washington, Seattle.\"\n ],\n \"GENES\": {\n \"ASPA\": {\n \"rs12948217\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"ASPA@DUB97270b2cfdca6\": {\n \"rs28940279\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"ASPA@DUB87440949378d9\": {\n \"rs28940574\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Familial Hyperinsulinism\": {\n \"result_options\": [\n \"0 Genetic Variant\",\n \"1 Genetic Variant\",\n \"2 or more Genetic Variants\"\n ],\n \"result\": \"0 Genetic Variant\",\n \"result_description\": \"Your analysis shows that you have no causal variant/s, which means you are not a carrier of FHI. \",\n \"risk_management\": \"Management of ABCC8 or KCNJ11-related FHI may need a more aggressive approach. A combination of drugs that suppress insulin secretion is given together with dietary interventions. Surgery may be needed in poor response to medication. \\n\\nIf a variant is detected in your genome or you suspect yourself to be a carrier due to family history, consult a healthcare professional for follow-up tests. You should also consider genetic counseling if you are planning to start a family with your partner, especially if you have a strong family history.\",\n \"risk_factors\": {\n \"Age of Onset\": \" Days after birth to a few months or years of life. \",\n \"Ethnicities\": \" FHI is most common in the Ashkenazi Jewish and Finnish populations, but it can also affect other races. \",\n \"Heredity\": \" Individuals with a family history of CD are more likely to develop the disease. \"\n },\n \"signs_and_symptoms\": \"The extremity of symptoms differs broadly among FHI patients. It ranges from irritability, seizures, reduced muscle tone, lack of energy, high birth weight, low blood sugar, and intellectual disabilities. Interestingly, some may not even present much symptoms. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Around 12-14 genes have been found to be correlated to FHI, with ABCC8 as the most frequent and KCNJ11 as less frequent. Other genes constitute a minuscule proportion of cases. Both ABCC8 and KCNJ11 genes synthesize the subunits that form a protein channel in the pancreatic beta cells. Mutations in these genes produce a faulty channel that disrupts the regulation of insulin resulting in aberrantly high insulin secretion. \",\n \"about\": \"Familial Hyperinsulinism (FHI), or sometimes referred to as Congenital Hyperinsulinism, is characterized by excessive levels of insulin. The hormone insulin manages blood sugar levels in the body. Abnormally high levels of insulin can cause recurring hypoglycemic or low blood sugar episodes. Insulin is synthesized and secreted from pancreatic beta cells. In FHI, two notable forms of the condition are described. Diffuse form occurs when all of the pancreatic beta cells release excessive insulin, while the focal form occurs when over-secretion happens to only some of the beta cells. Clinical presentation of FHI varies depending on the severity and onset of the disease. \",\n \"caption\": \"Frequent episodes of low blood sugar\",\n \"test_interpretation\": \"Interpretation:\\n\\nFamilial Hyperinsulinism most of the time manifests if a person has two copies of a genetic variant in the ABCC8 or KJN11 gene. Having just one copy only makes a person a carrier.\\n\\nNo genetic variants detected for this test mean that there is a greater chance that you are not a carrier for a FHI mutation. But it does not completely eliminate the probability of still being a carrier, especially if you belong to the most commonly affected ethnicities. Having one or more variants detected means that you are a carrier of the mutated variant associated with FHI. \\n\\nLimitations:\\n\\nThis tests for a subset of variants that cause Familial Hyperinsulinism. However, this does not test for all possible variants associated with it. Furthermore, this test does not diagnose you for Familial Hyperinsulinism, nor does it offer any medical solutions.\",\n \"main_genes\": \"ABCC8, KCNJ11\",\n \"reference\": [\n \"1.\\tGlaser, B., Blech, I., Krakinovsky, Y., Ekstein, J., Gillis, D., Mazor-Aronovitch, K., Landau, H., & Abeliovich, D. (2011). ABCC8 mutation allele frequency in the Ashkenazi Jewish population and risk of focal hyperinsulinemic hypoglycemia. Genetics in Medicine, 13(10), 891–894. https://doi.org/10.1097/gim.0b013e31821fea33\",\n \"2.\\tNestorowicz, A. (1996). Mutations in the sulonylurea receptor gene are associated with familial hyperinsulinism in Ashkenazi Jews. Human Molecular Genetics, 5(11), 1813–1822. https://doi.org/10.1093/hmg/5.11.1813\",\n \"3.\\tGalcheva, S., Demirbilek, H., Al-Khawaga, S., & Hussain, K. (2019). The Genetic and Molecular Mechanisms of Congenital Hyperinsulinism. Frontiers in Endocrinology, 10(111). https://doi.org/10.3389/fendo.2019.00111\",\n \"4.\\tOtonkoski, T., Ammala, C., Huopio, H., Cote, G. J., Chapman, J., Cosgrove, K., Ashfield, R., Huang, E., Komulainen, J., Ashcroft, F. M., Dunne, M. J., Kere, J., & Thomas, P. M. (1999). A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland. Diabetes, 48(2), 408–415. https://doi.org/10.2337/diabetes.48.2.408\",\n \"5.\\tGillis, D. (2003). Familial Hyperinsulinism. In M. P. Adam (Eds.) et. al., GeneReviews®. University of Washington, Seattle.\"\n ],\n \"GENES\": {\n \"ABCC8@DUB82526f6f5dfb9\": {\n \"rs137852672\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"ABCC8@DUB899cdfab51508\": {\n \"rs137852671\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"ABCC8@DUB21988588e07f0\": {\n \"rs72559722\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"ABCC8@DUB2473e04c24d95\": {\n \"rs761749884\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"KCNJ11\": {\n \"rs104894248\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"KCNJ11@DUB73664e096c434\": {\n \"rs104894236\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"KCNJ11@DUB73406e0a9ff33\": {\n \"rs267607196\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"KCNJ11@DUB8740ab360b01c\": {\n \"rs780957825\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Phenylketonuria\": {\n \"result_options\": [\n \"0 Genetic Variant\",\n \"1 Genetic Variant\",\n \"2 or more Genetic Variants\"\n ],\n \"result\": \"0 Genetic Variant\",\n \"result_description\": \"Your analysis shows that you have no causal variant/s, which means you are not a carrier of PKU. \",\n \"risk_management\": \"PKU treatment aims to maintain plasma phenylalanine concentrations within the normal range. This is usually accomplished by a carefully planned and controlled diet. Therapy must start at a very early age to avoid a degree of intellectual disability. Studies have consistently shown that PKU children treated with a low phenylalanine diet before the three months old perform well, with an IQ within the average range. \\n\\nIf a variant is detected in your genome or you suspect yourself to be a carrier due to family history, consult a healthcare professional for follow-up tests. You should also consider genetic counseling if you are planning to start a family with your partner, especially if you have a strong family history.\",\n \"risk_factors\": {\n \"Age of Onset\": \" From infancy \",\n \"Ethnicities\": \" All ethnicities are affected, although it is less common among individuals of African-American descent. \",\n \"Heredity\": \" Individuals with a family history of PKU are more likely to develop the disease. \"\n },\n \"signs_and_symptoms\": \"PKU signs and symptoms can range from mild to severe. These include a musty odor in the breath, skin, or urine, skin rashes (eczema), and fair skin and blue eyes. Neurological manifestations consist of seizures, microcephaly, hyperactivity, intellectual disability, delayed development, behavioral, emotional and social problems, and psychiatric disorders. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Hundreds of different variations in the PAH gene have been identified. These mutations lead to different degrees of activity of the PAH enzyme and, in turn, varying amounts of toxic phenylalanine elevation in the blood. \",\n \"about\": \"Phenylketonuria (PKU) is a rare hereditary condition that causes the body to accumulate an amino acid called phenylalanine. The PAH gene synthesizes the enzyme phenylalanine hydroxylase, which is required to break down phenylalanine. A defect in the PAH gene yields a faulty enzyme that causes PKU.\",\n \"caption\": \"Phenylalanine accumulation\",\n \"test_interpretation\": \"Interpretation:\\n\\nIndividuals with Phenylketonuria have two genetic variations in the PAH gene, with one variant being inherited from each parent. Each parent who has an altered gene copy is referred to as a carrier. \\n\\nNo genetic variants detected for this test mean that there is a greater chance that you are not a carrier for a PKU mutation. But it does not completely eliminate the probability of still being a carrier, especially if you belong to the most commonly affected ethnicities. Having one or more variants detected means that you are a carrier of the mutated variant associated with PKU. \\n\\nLimitations: \\n\\nThis tests for a subset of variants that cause Phenylketonuria. However, this does not test for all possible variants associated with it. Furthermore, this test does not diagnose you for Phenylketonuria, nor does it offer any medical solutions.\",\n \"main_genes\": \"PAH\",\n \"reference\": [\n \"1. Apold, J., Eiken, H. G., Svensson, E., Kunert, E., Kozak, L., Cechak, P., Güttler, F., Giltay, J., Lichter-Konecki, U., & Melle, D. (1993). The phenylketonuria G272X haplotype 7 mutation in European populations. Human genetics, 92(2), 107–109. https://doi.org/10.1007/BF00219674 \",\n \"2. Alibakhshi, R., Moradi, K., Mohebbi, Z., & Ghadiri, K. (2014). Mutation analysis of PAH gene in patients with PKU in western Iran and its association with polymorphisms: identification of four novel mutations. Metabolic brain disease, 29(1), 131–138. https://doi.org/10.1007/s11011-013-9432-0 \",\n \"3. Ajami, N., Kazeminezhad, S. R., Foroughmand, A. M., Hasanpour, M., & Aminzadeh, M. (2013). A preliminary mutation analysis of phenylketonuria in southwest Iran. Genetics and molecular research : GMR, 12(4), 4958–4966. https://doi.org/10.4238/2013.October.24.7 \",\n \"4. Bashyam, M. D., Chaudhary, A. K., Kiran, M., Nagarajaram, H. A., Devi, R. R., Ranganath, P., Dalal, A., Bashyam, L., Gupta, N., Kabra, M., Muranjan, M., Puri, R. D., Verma, I. C., Nampoothiri, S., & Kadandale, J. S. (2014). Splice, insertion-deletion and nonsense mutations that perturb the phenylalanine hydroxylase transcript cause phenylketonuria in India. Journal of cellular biochemistry, 115(3), 566–574. https://doi.org/10.1002/jcb.24692 \",\n \"5. Bean, L. J., Tinker, S. W., da Silva, C., & Hegde, M. R. (2013). Free the data: one laboratory's approach to knowledge-based genomic variant classification and preparation for EMR integration of genomic data. Human mutation, 34(9), 1183–1188. https://doi.org/10.1002/humu.22364 \",\n \"6. Bueno, M. A., González-Lamuño, D., Delgado-Pecellín, C., Aldámiz-Echevarría, L., Pérez, B., Desviat, L. R., & Couce, M. L. (2013). Molecular epidemiology and genotype-phenotype correlation in phenylketonuria patients from South Spain. Journal of human genetics, 58(5), 279–284. https://doi.org/10.1038/jhg.2013.16 \",\n \"\",\n \"7. Chen, C., Zhao, Z., Ren, Y., & Kong, X. (2018). Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 35(6), 791–795. https://doi.org/10.3760/cma.j.issn.1003-9406.2018.06.003 \",\n \"8. Couce, M. L., Bóveda, M. D., Fernández-Marmiesse, A., Mirás, A., Pérez, B., Desviat, L. R., & Fraga, J. M. (2013). Molecular epidemiology and BH4-responsiveness in patients with phenylalanine hydroxylase deficiency from Galicia region of Spain. Gene, 521(1), 100–104. https://doi.org/10.1016/j.gene.2013.03.004 \",\n \"9. Polak, E., Ficek, A., Radvanszky, J., Soltysova, A., Urge, O., Cmelova, E., Kantarska, D., & Kadasi, L. (2013). Phenylalanine hydroxylase deficiency in the Slovak population: genotype-phenotype correlations and genotype-based predictions of BH4-responsiveness. Gene, 526(2), 347–355. https://doi.org/10.1016/j.gene.2013.05.057 \",\n \"10. Vieira Neto, E., Laranjeira, F., Quelhas, D., Ribeiro, I., Seabra, A., Mineiro, N., Carvalho, L. M., Lacerda, L., & Ribeiro, M. G. (2019). Genotype-phenotype correlations and BH4 estimated responsiveness in patients with phenylketonuria from Rio de Janeiro, Southeast Brazil. Molecular genetics & genomic medicine, 7(5), e610. https://doi.org/10.1002/mgg3.610 \"\n ],\n \"GENES\": {\n \"PAH\": {\n \"rs62642926 \": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB35352b31b72c8\": {\n \"rs5030841\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB901522651df24\": {\n \"rs75193786 \": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB868090f7e3ba\": {\n \"rs76296470 \": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB95bfb01aad7e\": {\n \"rs5030846\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB89372c3fdd0d6\": {\n \"rs5030849\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB545b037706bde\": {\n \"rs5030850\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB79292efefd83c\": {\n \"rs62514952\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB9977618cab7a8\": {\n \"rs118203925\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB39985744d2cdf\": {\n \"rs5030851 \": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB437a35cee893f\": {\n \"rs5030853\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB6637994657891\": {\n \"rs62516092 \": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB1330f779e21b6\": {\n \"rs5030856\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB286414fa50240\": {\n \"rs5030857\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB26808f8e701ee\": {\n \"rs5030858\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB43357463afbc6\": {\n \"rs5030859\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB4425337c2ab3f\": {\n \"rs5030860\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB30781be847ff3\": {\n \"rs5030855\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"PAH@DUB839257f4a1b23\": {\n \"rs5030861\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Hereditary Fructosuria\": {\n \"result_options\": [\n \"0 Genetic Variant\",\n \"1 Genetic Variant\",\n \"2 or more Genetic Variants\"\n ],\n \"result\": \"0 Genetic Variant\",\n \"result_description\": \"Your analysis shows that you have no causal variant/s, which means you are not a carrier of Hereditary Fructosuria. \",\n \"risk_management\": \"A fructose-free diet is a preferred treatment for Hereditary Fructosuria. In order to avoid irreversible physical harm, it is necessary to diagnose this condition early and to follow a special diet. \\n\\nIf a variant is detected in your genome or you suspect yourself to be a carrier due to family history, consult a healthcare professional for follow-up tests. You should also consider genetic counseling if you are planning to start a family with your partner, especially if you have a strong family history.\",\n \"risk_factors\": {\n \"Age of Onset\": \" From infancy \",\n \"Ethnicities\": \" All ethnicities can be affected, but the disease is studied mostly among the European population. \",\n \"Heredity\": \" Individuals with a family history of Hereditary Fructosuria are more likely to develop the disease. \"\n },\n \"signs_and_symptoms\": \"Among infants, common symptoms may comprise prolonged vomiting, jaundice, growth retardation, occasional episodes of unconsciousness, and failure to thrive. Other symptoms involve liver enlargement and often cirrhosis, and due to deficiency of clotting factors, a tendency towards gastrointestinal bleeding.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Hereditary fructosuria has been associated with several mutations in the human aldolase B or ALDOB gene. This gene encodes the fructose-1,6-bisphosphate aldolase enzyme, which is involved in important metabolic processes in the body. Defects in the ALDOB gene can cause abnormal accumulation of fructose-1-phosphate in specific organs.\",\n \"about\": \"Hereditary fructosuria, also called hereditary fructose intolerance, is an inherited inability to digest fructose (fruit sugar) or its precursors (sugar, sorbitol, and brown sugar). This abnormality is caused by deficient activity of the enzyme fructose-1-phosphate aldolase, resulting in an accumulation of fructose-1-phosphate in the liver, kidney, and small intestine.\",\n \"caption\": \"Inability to digest fruit sugar\",\n \"test_interpretation\": \"Interpretation:\\n\\nIndividuals with Hereditary Fructosuria have two genetic variations in the ALDOB gene, with one variant being inherited from each parent. Each parent who has an altered gene copy is referred to as a carrier. \\n\\nNo genetic variants detected for this test mean that there is a greater chance that you are not a carrier for a mutation. But it does not completely eliminate the probability of still being a carrier, especially if you belong to the most commonly affected ethnicities. Having one or more variants detected means that you are a carrier of the mutated variant associated with this disorder. \\n\\nLimitations: \\n\\nThis tests for a subset of variants that cause Hereditary Fructosuria. However, this does not test for all possible variants associated with it. Furthermore, this test does not diagnose you, nor does it offer any medical solutions.\",\n \"main_genes\": \"ALDOB\",\n \"reference\": [\n \"1. Ferri, L., Caciotti, A., Cavicchi, C., Rigoldi, M., Parini, R., Caserta, M., Chibbaro, G., Gasperini, S., Procopio, E., Donati, M. A., Guerrini, R., & Morrone, A. (2012). Integration of PCR-Sequencing Analysis with Multiplex Ligation-Dependent Probe Amplification for Diagnosis of Hereditary Fructose Intolerance. JIMD reports, 6, 31–37. https://doi.org/10.1007/8904_2012_125 \",\n \"2. Gruchota, J., Pronicka, E., Korniszewski, L., Stolarski, B., Pollak, A., Rogaszewska, M., & Płoski, R. (2006). Aldolase B mutations and prevalence of hereditary fructose intolerance in a Polish population. Molecular genetics and metabolism, 87(4), 376–378. https://doi.org/10.1016/j.ymgme.2005.11.010 \",\n \"3. Morales-Alvarez, M. C., Ricardo-Silgado, M. L., Lemus, H. N., González-Devia, D., & Mendivil, C. O. (2019). Fructosuria and recurrent hypoglycemia in a patient with a novel c.1693T>A variant in the 3' untranslated region of the aldolase B gene. SAGE open medical case reports, 7, 2050313X18823098. https://doi.org/10.1177/2050313X18823098 \",\n \"4. Valadares, E. R., Cruz, A. F., Adelino, T. E., Kanufre, V., Ribeiro, M., Penido, M. G., Peret Filho, L. A., & Valadares, L. M. (2015). Hereditary fructose intolerance in Brazilian patients. Molecular genetics and metabolism reports, 4, 35–38. https://doi.org/10.1016/j.ymgmr.2015.05.007 \"\n ],\n \"GENES\": {\n \"ALDOB\": {\n \"rs1800546\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"ALDOB@DUB4736e1279e7b6\": {\n \"rs76917243 \": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"ALDOB@DUB927af06114def\": {\n \"rs78340951 \": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Autosomal Recessive Polycystic Kidney Disease\": {\n \"result_options\": [\n \"0 Genetic Variant\",\n \"1 Genetic Variant\",\n \"2 or more Genetic Variants\"\n ],\n \"result\": \"0 Genetic Variant\",\n \"result_description\": \"Your analysis shows that you have no causal variant/s, which means you are not a carrier of ARPKD. \",\n \"risk_management\": \"The treatment of ARPKD cases focuses on specific symptoms that are present in each patient. Particular therapies are aimed at preserving the function of the kidneys and liver. Many who have difficulty in breathing may need artificial ventilation to assist in breathing. Medications such as nitric oxide can help provide oxygen to the lungs, angiotensin-converting enzyme (ACE) inhibitors to control high blood pressure, and antibiotics to treat infections. \\n\\nIf a variant is detected in your genome or you suspect yourself to be a carrier due to family history, consult a healthcare professional for follow-up tests. You should also consider genetic counseling if you are planning to start a family with your partner, especially if you have a strong family history.\",\n \"risk_factors\": {\n \"Age of Onset\": \" From infancy to early adulthood \",\n \"Ethnicities\": \" ARPKD can occur in all ethnicities. \",\n \"Heredity\": \" Individuals with a family history of ARPKD are more likely to develop the disease. \"\n },\n \"signs_and_symptoms\": \"The severity and progression of ARPKD can differ considerably from person to person, even among members of the same family. Common symptoms include enlarged kidneys, hypertension, periportal fibrosis, polycystic kidney dysplasia, and abnormality of the intrahepatic bile duct. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"The PKHD1 gene contains instructions for creating a protein known as fibrocystin (or polyductin). The exact role of this protein in the body is still unclear. Fibrocystin may be involved in the proper formation or function of cilia, a hair-like structure found in most cells in the body. Variations in the PKHD1 gene may cause insufficient or no production of the fibrocystin protein in cells. \",\n \"about\": \"Autosomal recessive polycystic kidney disease (ARPKD) is a rare genetic condition characterized by the presence of fluid-filled cysts in the kidneys. Most affected individuals have swollen kidneys during the neonatal phase, and some cases can be fatal at this time. This disease affects 1 in 20,000 children. About 30% of newborns with ARPKD die within their first week of life.\",\n \"caption\": \"Fluid-filled kidney sacs\",\n \"test_interpretation\": \"Interpretation:\\n\\nIndividuals with ARPKD have two genetic variations in the PKHD1 gene, with one variant being inherited from each parent. Each parent who has an altered gene copy is referred to as a carrier. \\n\\nNo genetic variants detected for this test mean that there is a greater chance that you are not a carrier for a ARPKD mutation. But it does not completely eliminate the probability of still being a carrier, especially if you belong to the most commonly affected ethnicities. Having one or more variants detected means that you are a carrier of the mutated variant associated with ARPKD. \\n\\nLimitations: \\n\\nThis tests for a subset of variants that cause ARPKD. However, this does not test for all possible variants associated with it. Furthermore, this test does not diagnose you for ARPKD, nor does it offer any medical solutions.\",\n \"main_genes\": \"PKHD1\",\n \"reference\": [\n \"1. Krall, P., Pineda, C., Ruiz, P., Ejarque, L., Vendrell, T., Camacho, J. A., Mendizábal, S., Oliver, A., Ballarín, J., Torra, R., & Ars, E. (2014). Cost-effective PKHD1 genetic testing for autosomal recessive polycystic kidney disease. Pediatric nephrology (Berlin, Germany), 29(2), 223–234. https://doi.org/10.1007/s00467-013-2657-7 \",\n \"2. Perugorria, M. J., Masyuk, T. V., Marin, J. J., Marzioni, M., Bujanda, L., LaRusso, N. F., & Banales, J. M. (2014). Polycystic liver diseases: advanced insights into the molecular mechanisms. Nature reviews. Gastroenterology & hepatology, 11(12), 750–761. https://doi.org/10.1038/nrgastro.2014.155 \",\n \"3. Wang, J., Qi, D., Yang, J., Zhang, D., Wang, Q., Ju, X., & Zhong, X. (2019). Novel compound heterozygous PKHD1 mutations cause autosomal recessive polycystic kidney disease in a Han Chinese family. Molecular medicine reports, 20(6), 5059–5063. https://doi.org/10.3892/mmr.2019.10738 \"\n ],\n \"GENES\": {\n \"PKHD1 \": {\n \"rs137852944\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PKHD1 @DUB448f37e1d2c69\": {\n \"rs137852949\": {\n \"genotype\": \"GG\",\n \"effect_allels\": 0\n }\n },\n \"PKHD1 @DUB247c8eaa7073\": {\n \"rs398124502\": {\n \"genotype\": \"II\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Familial Mediterranean Fever\": {\n \"result_options\": [\n \"0 Genetic Variant\",\n \"1 Genetic Variant\",\n \"2 or more Genetic Variants\"\n ],\n \"result\": \"0 Genetic Variant\",\n \"result_description\": \"Your analysis shows that you have no causal variant/s, which means you are not a carrier of FMF. \",\n \"risk_management\": \"There is no known cure for FMF at present. Physicians focus on treating the symptoms experienced during FMF attacks. Daily use of colchicine is a popular FMF therapy that decreases inflammation. This therapy has been effective in preventing attacks of fever and amyloidosis. \\n\\nIf a variant is detected in your genome or you suspect yourself to be a carrier due to family history, consult a healthcare professional for follow-up tests. You should also consider genetic counseling if you are planning to start a family with your partner, especially if you have a strong family history.\",\n \"risk_factors\": {\n \"Age of Onset\": \" From infancy to 20 years old \",\n \"Ethnicities\": \" Sephardic (non-Ashkenazi) Jewish, Armenian, Arab, Turkish, Ashkenazi Jewish, Italians, Greeks, Spaniards, Cypriots, Northern Europeans, and Japanese \",\n \"Heredity\": \" Individuals with a family history of FMF are more likely to develop the disease. \"\n },\n \"signs_and_symptoms\": \"FMF is characterized by relatively brief, usually 1 to 3-day episodes of fever with serositis, synovitis, or skin rash. Young children often have frequent fevers. The occurrence of FMF attacks is variable, with an interval of days to years between episodes. In addition, the form of attack-be it abdominal, pleural, or arthritic may differ over time. People are generally symptom-free between attacks.\",\n \"star_rating\": 3,\n \"snp_table_caption\": \"Researchers identified the gene for FMF in 1997 and determined several gene mutations that triggered this hereditary rheumatic disease. The MEFV gene is located on the short arm of chromosome 16 that codes for pyrin, also called marenostrin, found almost exclusively in white blood cells that are essential to the immune response. The protein is likely to help keep inflammation under control by deactivating the immune response — without this \\\"brake,\\\" an unexpected full-blown inflammatory reaction takes place. \",\n \"about\": \"Familial Mediterranean Fever (FMF), also called recurrent polyserositis or familial paroxysmal polyserositis, is a rare hereditary disorder. It is most frequent among individuals with non-Ashkenazi Jewish, Armenian, Arab, and Turkish backgrounds. In these populations, as many as 1 in 200 individuals have the disease, with 1 in 5 acting as a carrier of the illness. \",\n \"caption\": \"Recurrent fever\",\n \"test_interpretation\": \"Interpretation:\\n\\nFMF appears only in individuals who received two copies of the mutant or altered gene, one from each parent. Having only one copy means you are a carrier.\\n\\nNo genetic variants detected for this test mean that there is a greater chance that you are not a carrier for a FMF mutation. But it does not completely eliminate the probability of still being a carrier, especially if you belong to the most commonly affected ethnicities. Having one or more variants detected means that you are a carrier of the mutated variant associated with FMF. \\n\\nLimitations: \\n\\nThis tests for a subset of variants that cause Familial Mediterranean Fever. However, this does not test for all possible variants associated with it. Furthermore, this test does not diagnose you, nor does it offer any medical solutions.\",\n \"main_genes\": \"MEFV\",\n \"reference\": [\n \"1. Celep, G., Durmaz, Z. H., Erdogan, Y., Akpinar, S., Kaya, S. A., & Guckan, R. (2019). The Spectrum of MEFV Gene Mutations and Genotypes in the Middle Northern Region of Turkey. The Eurasian journal of medicine, 51(3), 252–256. https://doi.org/10.5152/eurasianjmed.2019.18396 \",\n \"2. Feng, J., Zhang, Z., Li, W., Shen, X., Song, W., Yang, C., Chang, F., Longmate, J., Marek, C., St Amand, R. P., Krontiris, T. G., Shively, J. E., & Sommer, S. S. (2009). Missense mutations in the MEFV gene are associated with fibromyalgia syndrome and correlate with elevated IL-1beta plasma levels. PloS one, 4(12), e8480. https://doi.org/10.1371/journal.pone.0008480 \",\n \"3. Lee, H., Deignan, J. L., Dorrani, N., Strom, S. P., Kantarci, S., Quintero-Rivera, F., Das, K., Toy, T., Harry, B., Yourshaw, M., Fox, M., Fogel, B. L., Martinez-Agosto, J. A., Wong, D. A., Chang, V. Y., Shieh, P. B., Palmer, C. G., Dipple, K. M., Grody, W. W., Vilain, E., … Nelson, S. F. (2014). Clinical exome sequencing for genetic identification of rare Mendelian disorders. JAMA, 312(18), 1880–1887. https://doi.org/10.1001/jama.2014.14604 \",\n \"4. Li, Z., Akar, S., Yarkan, H., Lee, S. K., Çetin, P., Can, G., Kenar, G., Çapa, F., Pamuk, O. N., Pehlivan, Y., Cremin, K., De Guzman, E., Harris, J., Wheeler, L., Jamshidi, A., Vojdanian, M., Farhadi, E., Ahmadzadeh, N., Yüce, Z., Dalkılıç, E., … Akkoc, N. (2019). Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis. PLoS genetics, 15(4), e1008038. https://doi.org/10.1371/journal.pgen.1008038 \",\n \"5. Mansour, A. R., El-Shayeb, A., El Habachi, N., Khodair, M. A., Elwazzan, D., Abdeen, N., Said, M., Ebaid, R., ElShahawy, N., Seif, A., & Zaki, N. (2019). Molecular Patterns of MEFV Gene Mutations in Egyptian Patients with Familial Mediterranean Fever: A Retrospective Cohort Study. International journal of inflammation, 2019, 2578760. https://doi.org/10.1155/2019/2578760 \",\n \"6. Salehzadeh, F., Azami, A., Motezarre, M., Nematdoust Haghi, R., & Ahmadabadi, F. (2020). Neurological Manifestations in Familial Mediterranean Fever: a Genotype-Phenotype Correlation Study. Open access rheumatology : research and reviews, 12, 15–19. https://doi.org/10.2147/OARRR.S238649 \",\n \"7. Salehzadeh, F., Jafari Asl, M., Hosseini Asl, S., Jahangiri, S., & Habibzadeh, S. (2015). MEFV Gene Profile in Northwest of Iran, Twelve Common MEFV Gene Mutations Analysis in 216 Patients with Familial Mediterranean Fever. Iranian journal of medical sciences, 40(1), 68–72.\"\n ],\n \"GENES\": {\n \"MEFV\\n@DUB1801c7a0cc61d\": {\n \"rs28940578\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"MEFV\\n@DUB7346a37f7841\": {\n \"rs61752717\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"MEFV\\n@DUB481ff0b237aff\": {\n \"rs104895094\": {\n \"genotype\": \"TT\",\n \"effect_allels\": 0\n }\n },\n \"MEFV\\n@DUB42710ea31090a\": {\n \"rs28940579\": {\n \"genotype\": \"AA\",\n \"effect_allels\": 0\n }\n },\n \"MEFV\\n@DUB595ab325b2f38\": {\n \"rs61732874\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n },\n \"MEFV\\n@DUB664b84846bb0e\": {\n \"rs104895097\": {\n \"genotype\": \"CC\",\n \"effect_allels\": 0\n }\n }\n }\n },\n \"Salla Disease\": {\n \"result_options\": [\n \"0 Genetic Variant\",\n \"1 Genetic Variant\",\n \"2 or more Genetic Variants\"\n ],\n \"result\": \"0 Genetic Variant\",\n \"result_description\": \"Your analysis shows that you have no causal variant/s, which means you are not a carrier of the Salla disease. \",\n \"risk_management\": \"There is no specific treatment for free sialic acid storage diseases. Treatment is focused on the management of symptoms and on providing comfort and support for patients and their families. \\n\\nIf a variant is detected in your genome or you suspect yourself to be a carrier due to family history, consult a healthcare professional for follow-up tests. You should also consider genetic counseling if you are planning to start a family with your partner, especially if you have a strong family history.\",\n \"risk_factors\": {\n \"Age of Onset\": \" From infancy \",\n \"Ethnicities\": \" Salla disease is rare, but it is reported to be most common among the Finnish and Swedish populations. \",\n \"Heredity\": \" Individuals with a family history of Salla disease are more likely to develop the disorder. \"\n },\n \"signs_and_symptoms\": \"Some people may be more severely affected by Salla disease than others, even people who have the same form. The symptoms usually appear in the first year of life and may include low muscle tone (hypotonia), developmental delay and intellectual impairment, seizures, uncontrolled or uncoordinated movements (ataxia), stiff or rigid muscles (spasticity), involuntary writhing movement (athetosis), coarsening of facial features, and loss of motor and speech skills. \",\n \"star_rating\": 3,\n \"snp_table_caption\": \"All forms of free sialic acid storage diseases are caused by genetic variations in the SLC17A5 gene. This gene encodes a protein, sialin, which acts as a transport carrier of free sialic acid to various tissues in the body. Defective SLC17A5 gene caused by pathogenic variants may lead to the inefficient expression of the protein sialin.\",\n \"about\": \"Salla disease is a slow progressive adult form of free sialic acid storage disease. This disease is characterized by an intralysosomal accumulation of sialic acid in various tissues. Its general symptoms include developmental delay, low muscle tone, abnormal movements, and seizures. They are gradually progressive, and symptoms get worse over time. \",\n \"caption\": \"Slow developmental delay\",\n \"test_interpretation\": \"Interpretation:\\n\\nSalla disease appears only in individuals who received two copies of the mutant or altered gene, one from each parent. Having only one copy means you are a carrier. \\n\\nNo genetic variants detected for this test mean that there is a greater chance that you are not a carrier for a mutation. But it does not completely eliminate the probability of still being a carrier, especially if you belong to the most commonly affected ethnicities. Having one or more variants detected means that you are a carrier of the mutated variant associated with this disorder. \\n\\nLimitations: \\n\\nThis tests for a subset of variants that cause Salla disease. However, this does not test for all possible variants associated with it. Furthermore, this test does not diagnose you for Salla disease, nor does it offer any medical solutions.\",\n \"main_genes\": \"SLC17A5\",\n \"reference\": [\n \"1. Biancheri, R., Rossi, A., Verbeek, H. A., Schot, R., Corsolini, F., Assereto, S., Mancini, G. M., Verheijen, F. W., Minetti, C., & Filocamo, M. (2005). Homozygosity for the p.K136E mutation in the SLC17A5 gene as cause of an Italian severe Salla disease. Neurogenetics, 6(4), 195–199. https://doi.org/10.1007/s10048-005-0011-3 \",\n \"2. Leano, J. B., Batarni, S., Eriksen, J., Juge, N., Pak, J. E., Kimura-Someya, T., Robles-Colmenares, Y., Moriyama, Y., Stroud, R. M., & Edwards, R. H. (2019). Structures suggest a mechanism for energy coupling by a family of organic anion transporters. PLOS Biology, 17(5), e3000260. https://doi.org/10.1371/journal.pbio.3000260 \",\n \"3. Lindholm Carlström, E., Halvardson, J., Etemadikhah, M., Wetterberg, L., Gustavson, K. H., & Feuk, L. (2019). Linkage and exome analysis implicate multiple genes in non-syndromic intellectual disability in a large Swedish family. 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